Glycoside Hydrolase Family 1

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-D-fucosidase (EC 3.2.1.38); phlorizin hydrolase (EC 3.2.1.62); exo-β-1,4-glucanase (EC 3.2.1.74); 6-phospho-β-galactosidase (EC 3.2.1.85); 6-phospho-β-glucosidase (EC 3.2.1.86); strictosidine β-glucosidase (EC 3.2.1.105); lactase (EC 3.2.1.108); amygdalin β-glucosidase (EC 3.2.1.117); prunasin β-glucosidase (EC 3.2.1.118); vicianin hydrolase (EC 3.2.1.119); raucaffricine β-glucosidase (EC 3.2.1.125); thioglucosidase (EC 3.2.1.147); β-primeverosidase (EC 3.2.1.149); isoflavonoid 7-O-β-apiosyl-β-glucosidase (EC 3.2.1.161); ABA-specific β-glucosidase (EC 3.2.1.175); DIMBOA β-glucosidase (EC 3.2.1.182); β-glycosidase (EC 3.2.1.-); hydroxyisourate hydrolase (EC 3.-.-.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental); absent in plant myrosinases
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (19256); Uniprot accession (2276); PDB accession (243); 3D entries (53); cryst (0)
All (17237) Archaea (143) Bacteria (16013) Eukaryota (1033) Viruses (1) unclassified (47) Structure (53) Characterized (336)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 11 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF (fragment)   Elymus libanoticus AER62650.1    
 ORF (fragment)   Elymus libanoticus AER62651.1    
 ORF (fragment)   Elymus libanoticus AER62656.1    
 ORF (fragment)   Elymus spicatus AER62657.1    
 ORF (fragment)   Elymus spicatus AER62658.1    
 ORF (fragment)   Eremopyrum bonaepartis AER62665.1    
 ORF (fragment)   Eremopyrum triticeum AER62666.1    
 myrosinase (fragment)   Erysimum crepidifolium AKU41634.1    
 unnamed protein product   Eutrema halophilum BAJ34410.1 E4MXS7  
 unnamed protein product   Eutrema halophilum BAJ33819.1 E4MW36  
 unnamed protein product   Eutrema halophilum BAJ33862.1 E4MW79  
 unnamed protein product   Eutrema halophilum BAJ34035.1 E4MWQ2  
 unnamed protein product   Eutrema halophilum BAJ34435.1 E4MXV2  
 myrosinase (WjMYR)   Eutrema japonicum BAE16356.1 Q4AE75  
 rutin degrading enzyme   Fagopyrum tataricum ATW21594.1    
 β-glucosidase 1 (Bg1;FaBG1)   Fragaria x ananassa AFU61920.1    
 β-glucosidase 3 (Bg3;FaBG3)   Fragaria x ananassa AFU61922.1    
 β-glucosidase 2 (Bg2;FaBG2) (fragment)   Fragaria x ananassa AFU61921.1    
 β-glucosidase 1 (Bg1)   Fragaria x ananassa AHC04401.1    
 FFUJ_03187   Fusarium fujikuroi IMI 58289 CCT66182.1    
 FFUJ_01901   Fusarium fujikuroi IMI 58289 CCT61610.1    
 FFUJ_12099   Fusarium fujikuroi IMI 58289 CCT76035.1    
 FFUJ_03724   Fusarium fujikuroi IMI 58289 CCT65005.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF83012.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF83492.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF73859.1    
 β-glucosidase (Bgl1;BGL) 3.2.1.21 Fusarium oxysporum KCTC 16909 AGF69228.1    
 hydroxyisourate hydrolase (HIUHase) 3.5.2.17 Glycine max AAL92115.1
CAW42880.1
CAW48583.1
CBC08408.1
CBD21376.1
Q8S3J3  
 unnamed protein product   Glycine max CAW48549.1
ACU24039.1
CAW42846.1
CAW42903.1
CAW48606.1
CBC08374.1
CBD21342.1
   
 unnamed protein product   Glycine max CAW48550.1
CAW42847.1
CBC08375.1
CBD21343.1
   
 unnamed protein product   Glycine max CAW48553.1
CAW42850.1
CBC08378.1
CBD21346.1
   
 unnamed protein product   Glycine max CAW48554.1
CAW42851.1
CBC08379.1
CBD31974.1
   
 unnamed protein product   Glycine max CAW48555.1
CAW42852.1
CBC08380.1
CBD21348.1
   
 unnamed protein product   Glycine max CAW48600.1
CAW42897.1
CBC08425.1
CBD21393.1
   
 unnamed protein product   Glycine max CAW48602.1
ACU18054.1
CAW42899.1
CBC08427.1
CBD31945.1
   
 unnamed protein product   Glycine max CAW48603.1
CAW42900.1
CBC08428.1
CBD21396.1
CBD31941.1
   
 unnamed protein product   Glycine max CAW48546.1
CBC08371.1
CBD21339.1
   
 unnamed protein product   Glycine max CAW48547.1
CBC08372.1
CBD31943.1
   
 unnamed protein product   Glycine max CAW48548.1
CBC08373.1
CBD21341.1
   
 unnamed protein product (fragment)   Glycine max CAW48551.1
CBC08376.1
CBD21344.1
   
 unnamed protein product   Glycine max CAW48552.1
CBC08377.1
CBD21345.1
   
 unnamed protein product   Glycine max CAW48596.1
CBC08421.1
CBD21389.1
CBD31898.1
CBD31951.1
   
 unnamed protein product   Glycine max CAW48597.1
CBC08422.1
CBD21390.1
CBD31942.1
   
 unnamed protein product   Glycine max CAW48598.1
ACU24532.1
CBC08423.1
CBD21391.1
CBD31944.1
CBD31955.1
   
 unnamed protein product   Glycine max CAW48601.1
ACU22725.1
CBC08426.1
CBD21394.1
   
 unnamed protein product   Glycine max CAW48604.1
CBC08429.1
CBD31946.1
   
 unnamed protein product   Glycine max CAW48605.1
CBC08430.1
CBD21398.1
   
 unknown (fragment)   Glycine max ACU17400.1 C6T6G9  
 unnamed protein product   Glycine max CBD31896.1    
 unnamed protein product   Glycine max CBD31947.1    
 unnamed protein product   Glycine max CBD31950.1    
 unnamed protein product   Glycine max CBD31952.1    
 unnamed protein product   Glycine max CBD31953.1    
 unnamed protein product   Glycine max CBD31954.1    
 unnamed protein product   Glycine max CBD31897.1    
 unnamed protein product   Glycine max CBD31948.1    
 unnamed protein product   Glycine max CBD31949.1    
 unnamed protein product   Glycine max CBD31956.1    
 isoflavone conjugate-specific β-glucosidase (GmICHG) 3.2.1.161
3.2.1.21
Glycine max BAF34333.1 Q08IT7  
 Klotho (fragment)   Grampus griseus ADZ57973.1    
 ORF (fragment)   Griffithsia japonica AAM93923.1 Q7XZA1  
 β-galactosidase/β-glucosidase (BglA) 3.2.1.21
3.2.1.23
Hamamotoa singularis ATCC 24193 BAD95570.1 Q564N5  
 seminal fluid protein HACP047 (fragment)   Heliconius erato ADJ58542.1 D9HQ54  
 glucosidase (fragment)   Helicoverpa armigera GR ADF43507.1 D5G3H8  
 ORF (fragment)   Henrardia persica AER62667.1    
 P66 protein   Hevea brasiliensis AAO49267.1
ACH11662.1
CAW42879.1
CAW48582.1
CBC08407.1
CBD21375.1
CBG21222.1
Q84L69  
 cyanogenic β-glucosidase   Hevea brasiliensis AAP51059.1
CAW42878.1
CAW48581.1
CBC08406.1
CBD21374.1
CBG21220.1
Q7Y073  
 β-glucosidase (Vsp1;HbVSP1)   Hevea brasiliensis ABL01537.1    
 Klotho (fragment)   Hippopotamus amphibius AEB78523.1    
 lactase-phlorizin hydrolase (Lct) 3.2.1.108
3.2.1.62
Homo sapiens CAA30801.1
AAA59504.1
AAP12677.1
AAQ79768.1
AAX88924.1
ACM80708.1
ACM82337.1
NP_002290.1
P09848  
 lactase-phlorizin hydrolase (Lct) 3.2.1.108
3.2.1.62
Homo sapiens CAA30801.1
AAA59504.1
AAP12677.1
AAX88924.1
ACM80708.1
ACM82337.1
NP_002290.1
P09848  
 klotho (KL)   Homo sapiens BAA23382.1
AAQ41828.1
AAQ41829.1
ACP57343.1
ACP57344.1
BAA24940.1
BAA24941.1
BAG53456.1
CAH71888.1
CAR95139.1
CAR95140.1
Q9UEF7
Q9UEF7
Q9UEI9
Q9Y4F0
 
 klotho (KL)   Homo sapiens BAA23382.1
AAQ41828.1
AAQ41829.1
ACP57343.1
ACP57344.1
BAA24940.1
BAA24941.1
BAG53456.1
CAC94767.1
CAH71888.1
CAR95139.1
CAR95140.1
Q9UEF7
Q9UEF7
Q9UEI9
Q9Y4F0
 
 neutral β-glycosylceramidase / β-glucosidase (Gba3;CbgCBgl1;GluC;KLrP) (cytosolic) 3.2.1.21
3.2.1.62
Homo sapiens CAC08178.1
AAG39217.1
AAH29362.1
AAI01830.1
AAI09378.1
AAL37305.1
BAB18741.1
BAD96683.1
BAF85435.1
BAG36006.1
BAH12772.1
NP_066024.1
A8K9N1
Q9H227
2E9L[A]
2E9M[A]
2JFE[X]
2ZOX[A]
3VKK[A]
 LOC152831 (KLB;G6VTS68545) (klotho-like)   Homo sapiens BAC56857.1
AAH33021.1
AAI04872.1
AAI13654.1
AAI43576.1
AAQ41832.1
BAG63737.1
NP_783864.1
Q86Z14  
 LOC152831 (KLB;G6VTS68545) (klotho-like)   Homo sapiens BAC56857.1
AAI04872.1
AAI13654.1
AAI43576.1
AAQ41832.1
NP_783864.1
Q86Z14  
 KPVW3022/UNQ3022   Homo sapiens AAQ89091.1
ABA66378.1
ABH82958.1
ABI02344.1
ABI12629.1
ABJ30855.1
ABJ38985.1
ABJ43341.1
ABN29974.1
ABN30161.1
ABX91624.1
ABX91900.1
ABX92176.1
ABX92452.1
ABX92728.1
ABX93162.1
ABX93669.1
ABX94403.1
ABX95410.1
ABX95686.1
ABX95962.1
ABY04184.1
ABY04460.1
ABY04736.1
ABY05322.1
ABY16428.1
ABY17920.1
ABY18196.1
ABY18472.1
ACC17005.1
ACC30665.1
ACC36886.1
ACE07531.1
ACE09369.1
ACE10581.1
ACJ96144.1
ACN02410.1
ACN06820.1
ACP73535.1
ACP89063.1
ACR89013.1
ACR89565.1
ACW28655.1
BAG52192.1
NP_997221.1
NP_997221.2
Q6UWM7  
 ORF (fragment)   Hordeum marinum subsp. marinum AER62670.1    
 unnamed protein product   Hordeum vulgare CBD31906.1    
 unnamed protein product   Hordeum vulgare CBD31960.1    
 β-mannosidase / β-glucosidase (HvbMANNOS1) 3.2.1.21
3.2.1.25
Hordeum vulgare AAA87339.1
CAW42869.1
CAW48572.1
CBC08397.1
CBD21365.1
CBG21202.1
Q40025  
 NIASHv1004L05   Hordeum vulgare subsp. vulgare BAJ85274.1
CBD31959.1
   
 unnamed protein product   Hordeum vulgare subsp. vulgare BAJ93784.1
CBD31961.1
   
 unnamed protein product   Hordeum vulgare subsp. vulgare CBD31962.1
BAJ89480.1
   
 unnamed protein product   Hordeum vulgare subsp. vulgare CBD31958.1
BAJ89678.1
   
 predicted protein   Hordeum vulgare subsp. vulgare BAJ93012.1    
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAK08154.1    
 β-mannosidase / β-glucosidase (HvBII) 3.2.1.21
3.2.1.25
3.2.1.74
Hordeum vulgare subsp. vulgare ACF07998.1 B5A496  
 β-glucosidase (Bgl4;Bglhi) 3.2.1.21 Humicola grisea var. thermoidea IFO9854 / Humicola insolens RP86 BAA74958.1 O93784 4MDO[A]
4MDP[A]
 β-glucosidase (BglhI)   Humicola insolens RP86 AII80277.1    
 β-glucosidase (fragment)   Hyacinthus orientalis AAT08711.1 Q677B3  
 β-glucosidase 30 (Bglu30)   Hylocereus polyrhizus ASZ85203.1    
 ORF LCTL   Ictalurus punctatus AHH40387.1    
 ORF   Ipomoea nil BAN58137.1    
 JHL23J11.2   Jatropha curcas Palawan BAJ53147.1    
 Klotho (fragment)   Kogia sima ADZ57979.1    
 β-glucosidase 3.2.1.21 Lasiodiplodia theobromae CBS 247.96 CAJ81226.1    
 ArbB   Leishmania infantum AAG46031.1 Q9GPU3  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX97760.1 E5A243  
 ORF   Leptosphaeria maculans JN3 v23.1.3 CBX98890.1 E5A5J2  
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