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Glycoside Hydrolase Family 1

Activities in Family[retaining] anthocyanin 5-O-glucosyltransferase / 5-O-transglucosidase (EC 2.4.1.-);
[retaining] anthocyanin 7-O-glucosyltransferase / 7-O-transglucosidase (EC 2.4.1.-);
[retaining] β-transglucosidase (EC 2.4.1.-);
α-L-arabinopyranosidase (EC 3.2.1.-);
β-1,2-glucosidase (EC 3.2.1.-);
β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-);
Isoflavone 7-O-glucosyl β-glucosidase (EC 3.2.1.-);
3-a-(S)-strictosidine β-glucosidase (EC 3.2.1.105);
Lactase (EC 3.2.1.108);
Amygdalin β-glucosidase (EC 3.2.1.117);
Prunasin β-glucosidase (EC 3.2.1.118);
[retaining] vicianin hydrolase (EC 3.2.1.119);
Raucaffricine β-glucosidase (EC 3.2.1.125);
Myrosinase (EC 3.2.1.147);
β-primeverosidase (EC 3.2.1.149);
β-acuminosidase / β-apiosyl β-glucosidase / furcatin hydrolase (EC 3.2.1.161);
ABA-specific β-glucosidase (EC 3.2.1.175);
Exo-α-sialidase (EC 3.2.1.18);
DIMBOA β-glucosidase (EC 3.2.1.182);
Protodioscin 26-O-β-D-glucosidase (EC 3.2.1.186);
0-26-avenacosidase (EC 3.2.1.188);
Oleuropein β-glucosidase (EC 3.2.1.206);
β-glucosidase (EC 3.2.1.21);
β-galactosidase (EC 3.2.1.23);
β-mannosidase (EC 3.2.1.25);
β-glucuronidase (EC 3.2.1.31);
Xylan β-1,4-xylosidase (EC 3.2.1.37);
β-D-fucosidase (EC 3.2.1.38);
β-glucosylceramidase (EC 3.2.1.45);
β-galactosylceramidase (EC 3.2.1.46);
Exo-β-1,3-glucanase (EC 3.2.1.58);
Exo-β-1,4-glucanase / cellodextrinase (EC 3.2.1.74);
6-P-β-galactosidase (EC 3.2.1.85);
6-P-β-glucosidase (EC 3.2.1.86);
Mechanism Retaining e
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental); absent in plant myrosinases
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (66130); Uniprot accession (452); PDB accession (319); 3D entries (88); cryst (0)
Summary
Download GH1 (66258) Taxonomic display Structure (88) Characterized (368)
| 1 | 2 | 3 | 4 |
Archaea
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 multifunctional β-glycosidase (β-Gly; Asβ-Gly; ASAC_1390) 3.2.1.21
3.2.1.23		 pubmed
pubmed
 Acidilobus saccharovorans 345-15 ADL19795.1 D9PZ08 4HA3[A]
4HA4[A]
 Cmaq_0408 3.2.1.21 pubmed
 Caldivirga maquilingensis IC-167 ABW01253.1 A8MBR0  
 Cmaq_0652 3.2.1.21 pubmed
 Caldivirga maquilingensis IC-167 ABW01492.1 A8MCI6  
 β-galactosidase (PTO1453) 3.2.1.23 pubmed
 Picrophilus torridus DSM 9790 AAT44038.1    
 β-galactosidase (CelB) 3.2.1.23 pubmed
 Pyrococcus furiosus B232 AHW49177.1 Q51723  
 β-mannosidase (BglB;PF0356) 3.2.1.25 pubmed
 Pyrococcus furiosus DSM 3638 NP_578085.1
AAL80480.1		 Q8U3U9  
 β-glucosidase / β-rutinosidase (Cel1A;CelB;BGLPf;PfBgl1;PFTG;PF0073;Pf-β-gly) 3.2.1.21
3.2.1.-		 pubmed
pubmed
 Pyrococcus furiosus DSM 3638 AAL80197.1
AAC25555.1
ABC06396.1
NP_577802.1		 E7FHY4
Q51723		 3APG[A,B,C,D]
3WDP[P,Q,R,S]
3WQ8[A,B,C,D,E,F,G,H,I,J,K,L]
 β-mannosidase / β-galactosidase (BmnA;PF1208) 3.2.1.23
3.2.1.25		 pubmed
pubmed
 Pyrococcus furiosus DSM 3638 AAL81332.1
AAC44387.1
AAM56789.1
ABC06395.1
CAH68690.1
CAT81449.1
NP_578937.1		 E7FHC0
Q51733		  
 β-glucosidase (BglA; Bgl; PF0442) (Cel1B) 3.2.1.21 pubmed
 Pyrococcus furiosus DSM 3638 AAL80566.1
AAG28457.1
NP_578171.1		 E7FI48
Q9HHB3		  
 alkyl β-glucosidase (membrane-bound) (BGPh;BglA;PH0366) 3.2.1.21 pubmed
 Pyrococcus horikoshii OT3 BAA29440.1
ABC06393.1
NP_142340.1		 O58104 1VFF[A]
 β-mannosidase (BglB;PH0501) 3.2.1.25 pubmed
 Pyrococcus horikoshii OT3 BAA29589.1
ABC06394.1
NP_142473.1		 O58237  
 β-galactosidase 3.2.1.23 pubmed
 Pyrococcus woesei AAB97862.1 O52629  
 β-glycosidase (Bgly;SSG) 3.2.1.21 pubmed
 Saccharolobus shibatae AAA79030.1 P50388  
 β-glycosidase / β-galactosidase 3.2.1.21
3.2.1.23		 doi
doi
 Saccharolobus solfataricus DSM1616 CAA34074.1 P14288  
 β-glycosidase S (LacS; Ss-β-gly; SSO3019) 3.2.1.21
3.2.1.23		 pubmed
pubmed
 Saccharolobus solfataricus P2 AAA72843.1
AAE29896.1
AAK43121.1
ABC06397.1
ACW34039.1
CAC24042.1
CAJ18790.1
NP_344331.1		 P22498 1GOW[A,B]
1UWI[A,B,C,D]
1UWQ[A,B]
1UWR[A,B]
1UWS[A,B]
1UWT[A,B]
1UWU[A,B]
2CEQ[A,B]
2CER[A,B]
4EAM[A,B]
4EAN[A,B]
5I3D[A,B,C,D]
5IXE[A,B]
7UZ1[A,B]
7UZ2[A,B]
 β-glycosidase (BgaS;Saci_1849) 3.2.1.21 pubmed
 Sulfolobus acidocaldarius DSM 639 AAY81155.1
YP_256448.1		 P14288  
 β-glycosidase (TK1827) 3.2.1.21 pubmed
 Thermococcus kodakarensis KOD1 BAD86016.1
CAT70991.1		 Q5JDV2  
 β-glycosidase (Tkbgly;TK1761) 3.2.1.21
3.2.1.23		 pubmed
pubmed
 Thermococcus kodakarensis KOD1 BAA78713.1
BAD85950.1
CAT70557.1		 Q5JDT7
Q9YGB8		  
 β-glucosidase (BglT) 3.2.1.21 pubmed
 Thermococcus sp. AL662 CAA94187.1 O08324  
 β-glucosidase (TsBGL; B6U94_07015) 3.2.1.21 pubmed
 Thermofilum sp. ex4484_79 OYT30282.1   7F1N[A,B]
 TVG0691226 3.2.1.21
3.2.1.23		 pubmed
pubmed
 Thermoplasma volcanium GSS1 BAB59827.1
NP_111204.1		 Q97AX4  
 β-glucosidase (Tα-β-gly;Gly) 3.2.1.21 pubmed
 Thermosphaera aggregans M11TL AAD43138.1
AAM56782.1		 Q9YGA8 1QVB[A,B]
 β-glucosidase (Vul_Bgl1A) 3.2.1.21 pubmed
 uncultured archaeon QGN01269.1    
 β-glucosidase (Bgl1) 3.2.1.108
3.2.1.21
3.2.1.38		 pubmed
pubmed
pubmed
 uncultured archaeon CDG15325.1 W8W3B8  
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 exo-β-glucosidase 1A (BglA; β-G; HtBgl; Cthe_0212) (Glc1A) 3.2.1.21 pubmed
 Acetivibrio thermocellus ATCC 27405 CAA42814.1
AAQ79758.1
ABN51453.1		 P26208 5OGZ[A,B]
8IVY[A,B]
 β-glucosidase (Acel_0133) 3.2.1.21 pubmed
 Acidothermus cellulolyticus 11B ABK51908.1 A0LR48  
 β-glucosidase (Abg) 3.2.1.21 pubmed
 Agrobacterium sp. ATCC21400 AAA22085.1
AAQ79763.1		 P12614  
 β-glucosidase (AacGH1) 3.2.1.21 pubmed
 Alicyclobacillus acidiphilus WP_067621817.1   6ZIV[AAA,BBB,CCC,DDD,EEE,FFF,GGG,HHH]
 β-glycosidase (GlyB;Aaci_1895) 3.2.1.21
3.2.1.23		 pubmed
pubmed
 Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 ACV58907.1
AAZ81839.1		 C8WXU5
Q0R5R7		  
 β-glucosidase (AheGH1) 3.2.1.21
3.2.1.38
3.2.1.-		 pubmed
pubmed
pubmed
 Alicyclobacillus herbarius   A0A8I3B065 6YN7[A,B,C,D]
 Aflv_2360 3.2.1.21 pubmed
 Anoxybacillus flavithermus WK1 ACJ34717.1 B7GM33  
 β-glucosidase (BglZ) 3.2.1.21 pubmed
 Bacillus amyloliquefaciens ABBD AFS64714.1 J9ZZW8  
 BLi04199 / BL01946 3.2.1.21 pubmed
 Bacillus licheniformis DSM 13 = ATCC 14580 AAU43012.1
AAU25633.1
CBG21160.1		 Q65D52  
 6-P-β-glucosidase (BglH; BlBglH; BLi04214; BL00212) 3.2.1.86 pubmed
 Bacillus licheniformis DSM 13 = ATCC 14580 AAU43027.1
AAU25648.1		 Q65D37 6WGD[A,B,C]
 BLi00387 or BL01718 (YckE; BlBglC) 3.2.1.38 pubmed
 Bacillus licheniformis DSM 13 = ATCC 14580 AAU39345.1
AAU21991.1
CBG21156.1		 Q65NL9 7M1R[A,B,C,D]
 β-glucosidase (Bgl1A; BsBgl1A) 3.2.1.21 pubmed
 Bacillus sp. CGMCC 1.16541 QMX85751.1
WP_110112460.1		 A0A7G5WHW4  
 β-glucosidase A 3.2.1.21 pubmed
 Bacillus sp. GL1 BAA36160.1
CBG21242.1		 Q9ZNN7  
 aryl β-glucosidase (BglC) 3.2.1.21 pubmed
 Bacillus sp. SJ-10 AHC94275.1 V9VGK4  
 6-P-β-glucosidase (YdhP;BSU05840) 3.2.1.86 pubmed
 Bacillus subtilis subsp. subtilis str. 168 BAA19708.1
AIY91871.1
AQR80536.1
AQR84749.1
CAB12403.1
CBG21028.1
NP_388465.1		 A0A6M3Z8A5
O05508		  
 6-P-β-glucosidase (BglA;BSU40110) 3.2.1.86 pubmed
 Bacillus subtilis subsp. subtilis str. 168 AAA22660.1
AIY95329.1
AQR84054.1
AQR88269.1
BAA11270.1
CAB16048.1
CBG21250.1
NP_391891.1		 A0A6M4JR50
P42973		  
 6-P-β-glucosidase 1 (BglH;N17D;BSU39260) 3.2.1.86 pubmed
 Bacillus subtilis subsp. subtilis str. 168 CAB15962.2
AIY95585.1
AQR83968.1
AQR88183.1
CAA84287.1
CBG21247.1
NP_391805.1		 A0A6M3ZHY9
P40740		  
 6-P-β-glucosidase (YckE;BglC;BSU03410) 3.2.1.86 pubmed
 Bacillus subtilis subsp. subtilis str. 168 CAB12135.1
AIY91623.1
AQR80279.1
AQR84492.1
BAA06429.1
BAA08975.1
CBG21248.1
NP_388223.1		 A0A6M3ZAF5
P42403		  
 β-glucosidase / β-xylosidase (BglB;P11-6B) 3.2.1.21
3.2.1.37		 pubmed
pubmed
 bacterium enrichment culture clone P11-6B ADT62000.1 E9KYU3  
 β-glucosidase (BaBgl3B; BAD_1287) 3.2.1.21 pubmed
 Bifidobacterium adolescentis ATCC 15703 BAF40068.1    
 β-glucosidase (Bbg572) 3.2.1.21 pubmed
 Bifidobacterium animalis subsp. lactis AFS33105.1    
 β-glucosidase / β-D-fucosidase 3.2.1.21
3.2.1.38		 pubmed
pubmed
 Bifidobacterium breve 203 / clb BAA19881.1
CBG21199.1		 P94248  
 β-glucosidase / cellodextrinase (CldC; Bbr_0109) 3.2.1.21 pubmed
 Bifidobacterium breve UCC2003 ACT78497.1
ABE94821.1		 F1LL52  
 β-glucosidase (Bgl13;Calkr_2207) 3.2.1.21 URL
 Caldicellulosiruptor acetigenus I77R1B ADQ41669.1 E4S6B1  
 β-glucosidase / cellodextrinase (CbBgl1A;CbCdx1A;Athe_0458) (Bgl1A=Cdx1A) 3.2.1.21 doi
 Caldicellulosiruptor bescii DSM 6725 ACM59590.1 B9MNR1  
 β-glucosidase A (BglA) 3.2.1.21 pubmed
 Caldicellulosiruptor saccharolyticus CAA31087.1
AAQ79759.1
CBG21257.1		 P10482  
 β-glucosidase (BglA;Csac_1089) 3.2.1.21 pubmed
 Caldicellulosiruptor saccharolyticus DSM 8903 ABP66702.1 A4XIG7  
 β-galactosidase 3.2.1.23 doi
 Caldicellulosiruptor sp. enrichment culture clone YTY-70 AFQ98284.1 J7KFN3  
 β-glucosidase (BlgA) 3.2.1.21 pubmed
 Caldicellulosiruptor sp. F32 AFO70070.1 I7DLX2  
 CCNA_02220 3.2.1.21 pubmed
 Caulobacter vibrioides NA1000 ACL95685.1 A0A0H3C9V1
B8GXX8		  
 β-glucosidase (Cba4) 3.2.1.21 pubmed
 Cellulomonas biazotea ATCC 486 ASU50143.1    
 cellobiase / β-glucosidase (Cba3) 3.2.1.21 pubmed
 Cellulomonas biazotea ATCC 486 AEM45802.1 G1C1T5  
 β-glucosidase (CfBgl1;Celf_2783) 3.2.1.21 pubmed
 Cellulomonas fimi ATCC 484 AEE46907.1 F4H7E6  
 Cfla_1084 3.2.1.21 pubmed
 Cellulomonas flavigena DSM 20109 ADG73989.1 D5ULE7  
 Rsph17025_1146 3.2.1.21 pubmed
 Cereibacter sphaeroides ATCC 17025 ABP70047.1 A4WRN3  
 β-glucosidase A (BglA;BG) 3.2.1.21 pubmed
 Clostridium cellulovorans AAQ00997.1
CBG21209.1		 Q53EH2 3AHX[A,B,C,D]
 6-P-β-glucosidase (AbgA) 3.2.1.86 pubmed
 Clostridium longisporum AAC05714.1 Q46130  
 ESA_02547 3.2.1.86 pubmed
 Cronobacter sakazakii ATCC BAA-894 ABU77792.1 A7MJ23  
 β-glucosidase (Deide_00550) 3.2.1.21 pubmed
 Deinococcus deserti VCD115 ACO44852.1 C1CXP6  
 β-glucosidase A (BglA;DP2448) 3.2.1.21 pubmed
 Desulfotalea psychrophila LSv54 CAG37177.1
YP_066184.1		 Q6AKE8  
 β-glucosidase (DtGH; DICTH_1689) 3.2.1.21 pubmed
 Dictyoglomus thermophilum H-6-12 ACI19973.1 B5YAN1  
 β-glucosidase (Dtur?Glu; Dtur_0462) 3.2.1.21 pubmed
 Dictyoglomus turgidum DSM 6724 ACK41762.1 B8E1X9  
 β-galactosidase (Dtur_1799) 3.2.1.21 pubmed
 Dictyoglomus turgidum DSM 6724 ACK43071.1 B8E0Q1  
 6-P-β-glucosidase (AscB;ECs3572) 3.2.1.86 pubmed
 Escherichia coli O157:H7 str. Sakai BAB36995.1
NP_311599.1		 Q8X841  
 6-P-β-glucosidase (BglB;b3721) 3.2.1.86 pubmed
 Escherichia coli str. K-12 substr. MG1655 AAC76744.1
AAA23511.1
AAA62072.1
AAA83838.1
AAQ79757.1
AIZ93475.1
ALI38586.1
AMC96613.1
AUG18433.1
AVI53891.1
AYG21461.1
NP_418177.1		 P11988  
 6-P-β-glucosidase 2 (AscB;b2716) 3.2.1.86 pubmed
 Escherichia coli str. K-12 substr. MG1655 AAA69226.1
AAA16430.1
AAC75758.1
AIZ93701.1
ALI42228.1
AMC98974.1
AUG19188.1
AVI56782.1
AYG21513.1
NP_417196.1		 P24240  
 6-P-β-glucosidase A (BglA;b2901) 3.2.1.86 pubmed
 Escherichia coli str. K-12 substr. MG1655 AAC75939.1
AAA83082.1
AUG17619.1
AVI53071.1
AYG18126.1
CBG20988.1
NP_417377.1		 Q46829 2XHY[A,B,C,D]
 β-glucosidase (BglA;EaBglA;EaBgl1A;Eab7_0297) 3.2.1.21 pubmed
 Exiguobacterium antarcticum B7 Eab7 AFS69459.1 K0A8J9 5DT5[A,B,C,D,E,F,G,H]
5DT7[A,B,C,D]
 EAT1b_2183 3.2.1.21 doi
 Exiguobacterium sp. AT1b ACQ71106.1 C4L1S4 6WIU[A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P]
 β-glucosidase (BglA) 3.2.1.21 doi
 Exiguobacterium sp. DAU5 ADK47980.1 E0X9H4  
 β-glucosidase / β-glucosaccharase (BglG) 3.2.1.21 pubmed
 Exiguobacterium sp. GXG2 AKA66375.1    
 β-glucosidase (FiBgl1A) (Bgl1A) 3.2.1.21 pubmed
 Fervidobacterium islandicum CCA60742.1 G8YZD7  
 Fnod_1558 3.2.1.21 pubmed
 Fervidobacterium nodosum Rt17-B1 ABS61401.1 A7HNB8  
 β-glucosidase (BglA) 3.2.1.21 pubmed
 Fervidobacterium sp. YNP AAN60220.1 Q8GKQ8  
 6-P-β-glucosidase (PbgA) 3.2.1.86 pubmed
 Fusobacterium mortiferum AAB49339.1 P94793  
 β-galactosidase (GKGal1A;GK2337) (Gal1A) 3.2.1.23 doi
 Geobacillus kaustophilus HTA426 BAD76622.1
CBG21168.1		 Q5KXG4  
 6-phospho-β-glycosidase (GK3214) 3.2.1.85
3.2.1.86		 pubmed
pubmed
 Geobacillus kaustophilus HTA426 BAD77499.1
CBG21169.1		 Q5KUY7  
 6-phospho-β-glycosidase (GK1856) 3.2.1.85
3.2.1.86		 pubmed
pubmed
 Geobacillus kaustophilus HTA426 BAD76141.1
CBG21167.1		 Q5KYU5  
 6-P-β-glucosidase (CelA; Cel1A) 3.2.1.86 pubmed
 Geobacillus stearothermophilus T-1 QKV28200.1    
 bifunctional 6-P-β-galactosidase / 6-P-β-glucosidase (Gan1D) 3.2.1.85
3.2.1.86		 pubmed
pubmed
 Geobacillus stearothermophilus T-1 AHL67640.1 W8QF82 4ZE4[A,B]
4ZE5[A,B,C,D]
4ZEH[A,B,C,D]
4ZEN[A,B]
4ZEP[A,B]
4ZFM[A,B,C,D]
5OK7[A,B,C,D]
5OKA[A,B,C,D]
5OKB[A,B,C,D]
5OKE[A,B,C,D]
5OKG[A,B,C,D]
5OKH[A,B]
5OKJ[A,B]
5OKK[A,B]
5OKQ[A,B]
5OKR[A,B]
5OKS[A,B]
8B80[A,B]
8B81[A,B]
 HCH_06907 3.2.1.21 pubmed
 Hahella chejuensis KCTC 2396 ABC33525.1 Q2S749  
 β-glucosidase (BglA;BH1923) 3.2.1.21 pubmed
 Halalkalibacterium halodurans C-125 BAB05642.1
CBG20998.1
NP_242789.1		 Q9KBK3  
 β-galactosidase (BgalH) 3.2.1.23 pubmed
 Halomonas sp. S62 AFA35120.1 H6WX44  
 β-glucosidase A (BglA;HoBGLA;Hore_15280) 3.2.1.21 pubmed
 Halothermothrix orenii H 168 ACL70277.1 B8CYA8 3TA9[A,B]
4PTV[A,B]
4PTW[A,B]
4PTX[A,B]
 β-glucosidase (BglD5; JMA_34740) 3.2.1.21   Jeotgalibacillus malaysiensis D5 AJD92791.1 A0A0B5ARU7  
 6-P-β-glucosidase (BglB) 3.2.1.86 pubmed
 Klebsiella aerogenes AN292 AAM82757.1 Q8KP24  
 6-P-β-glucosidase / phospho-cellobiase (CasB) 3.2.1.86 pubmed
 Klebsiella oxytoca P2 AAB51564.1
CBG21258.1		 Q48409  
 [ginsenoside] β-glucosidase (KfGH01W; Kfla_5268) 3.2.1.21 pubmed
 Kribbella flavida DSM 17836 ADB34282.1   6M6L[A,B]
6M6M[A,B]
 6-P-β-galactosidase 3.2.1.85 pubmed
 Lacticaseibacillus casei AAD15134.1
AAA25238.1
AAQ79754.1
CAB02557.1
CBG21260.1		 P14696  
 aryl 6-P-β-glucosidase (BglH;BglT) 3.2.1.86 pubmed
 Lactiplantibacillus plantarum B21 CAA75906.1 O86291  
 β-galactosidase (Pbg6; lp_3011) 3.2.1.23 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD65191.1
CBG21084.1
CCC80068.1
NP_786331.1		    
 6-P-β-galactosidase (Pbg5; lp_2778) 3.2.1.85 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD65007.1
CBG21083.1
CCC79886.1
NP_786156.1		    
 β-galactosidase (Pbg7; lp_3132) 3.2.1.23 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD65295.1
CBG21085.1
CCC80172.1
NP_786432.1		    
 6-P-β-galactosidase / 6-P-β-glucosidase (Pbg9; lp_3525) 3.2.1.85
3.2.1.86		 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD65609.1
CBG21087.1
CCC80491.1
NP_786731.1		    
 β-galactosidase (Bgl; lp_3629) 3.2.1.23 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD65701.1
AAS68346.1
CBG21089.1
CCC80585.1
NP_786823.1		   5NAQ[A,B,C,D,E,F]
5NAV[A,B,C,D,E,F]
 β-galactosidase (Pbg2; lp_0906) 3.2.1.23 pubmed
 Lactiplantibacillus plantarum WCFS1 CAD63475.1
CBG21080.1
CCC78348.1
NP_784630.1		    
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