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Glycoside Hydrolase Family 1

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-D-fucosidase (EC 3.2.1.38); phlorizin hydrolase (EC 3.2.1.62); exo-β-1,4-glucanase (EC 3.2.1.74); 6-phospho-β-galactosidase (EC 3.2.1.85); 6-phospho-β-glucosidase (EC 3.2.1.86); strictosidine β-glucosidase (EC 3.2.1.105); lactase (EC 3.2.1.108); amygdalin β-glucosidase (EC 3.2.1.117); prunasin β-glucosidase (EC 3.2.1.118); vicianin hydrolase (EC 3.2.1.119); raucaffricine β-glucosidase (EC 3.2.1.125); thioglucosidase (EC 3.2.1.147); β-primeverosidase (EC 3.2.1.149); isoflavonoid 7-O-β-apiosyl-β-glucosidase (EC 3.2.1.161); ABA-specific β-glucosidase (EC 3.2.1.175); DIMBOA β-glucosidase (EC 3.2.1.182); β-glycosidase (EC 3.2.1.-); hydroxyisourate hydrolase (EC 3.-.-.-); β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-); protodioscin 26-O-β-D-glucosidase (EC 3.2.1.186)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental); absent in plant myrosinases
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (54203); Uniprot accession (433); PDB accession (291); 3D entries (80); cryst (0)
Summary
Download GH1 (52155) Taxonomic display Structure (80) Characterized (338)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 amygdalin β-glucosidase I (AH I;AH1) 3.2.1.117 pubmed
 Prunus serotina AAA93234.2
AAL07489.1
CAW42871.1
CAW48574.1
CBC08399.1
CBD21367.1		 P29259
P29260
P29261
P29262
Q40984
Q945G7		  
 myrosinase (RMB2) 3.2.1.147 pubmed
 Raphanus sativus BAB17227.1 Q9FXR0  
 myrosinase (RMB1) 3.2.1.147 pubmed
 Raphanus sativus BAB17226.1 Q9FXR1  
 β-glucosidase 1 (Bg1;BglI;BGIV) 3.2.1.21 pubmed
 Rasamsonia emersonii CBS 814.70 AAL34084.2
AAL89551.1		 Q8X214  
 strictosidine β-glucosidase (Sgr1;SG) 3.2.1.105 pubmed
 Rauvolfia serpentina CAC83098.1
CBG21226.1		 Q8GU20 2JF6[A,B]
2JF7[A,B]
3ZJ7[A,B]
3ZJ8[A,B]
 raucaffricine O-β-glucosidase (RG) 3.2.1.125 pubmed
 Rauvolfia serpentina AAF03675.1 Q9SPP9 3U57[A,B]
3U5U[A,B]
3U5Y[A,B]
3ZJ6[A,B]
4A3Y[A,B]
4ATD[A,B]
4ATL[A,B]
4EK7[A,B]
 β-glucosidase (BGluc-1;RfBGluc-1) 3.2.1.21
3.2.1.37
3.2.1.38		 pubmed
pubmed
pubmed
 Reticulitermes flavipes ADK12988.1 D9ILU1  
 male-specific β-glycosidase (Lmα-p72) 3.2.1.23 pubmed
 Rhyparobia maderae AAL40863.1 Q8WQL9  
 β-glucosidase (ScGlu) (plastidic) 3.2.1.21
3.2.1.182		 doi
doi
 Secale cereale AAG00614.1
CAW42885.1
CAW48588.1
CBC08413.1
CBD21381.1
CBG21237.1		 Q9FYS3 3AIU[A]
3AIV[A]
3AIW[A]
 β-glucosidase, partial (fragment) 3.2.1.21 pubmed
 Sicyos edulis QIA00482.1 A0A6C0R7S1  
 myrosinase 3.2.1.147 pubmed
 Sinapis alba CAA42533.1 P29736
Q7SIB0		 1DWA[M]
1DWF[M]
1DWG[M]
1DWH[M]
1DWI[M]
1DWJ[M]
1E4M[M]
1E6Q[M]
1E6S[M]
1E6X[M]
1E70[M]
1E71[M]
1E72[M]
1E73[M]
1MYR[A]
1W9B[M]
1W9D[M]
2MYR[A]
2WXD[M]
 β-mannosidase (LeMside 2) 3.2.1.25 pubmed
 Solanum lycopersicum AAL37719.1
AAL37714.1
CBD28478.1		 Q8VWL8  
 cyanogenic β-glucosidase (dhurrinase-2) 3.2.1.21 doi
 Sorghum bicolor AAK49119.1
CAW42882.1
CAW48585.1
CBC08410.1
CBD21378.1
CBG21230.1		 Q93XR2  
 cyanogenic β-glucosidase / dhurrinase 1 (Dhr1) 3.2.1.21 pubmed
 Sorghum bicolor P721N AAC49177.1
CAW42873.1
CAW48576.1
CBC08401.1
CBD21369.1
CBG21205.1		 Q41290 1V02[A,B,C,D,F]
1V03[A]
 β-glycosidase (β-gly;Sfbgly) 3.2.1.21
3.2.1.23
3.2.1.38		 pubmed
pubmed
pubmed
 Spodoptera frugiperda AAC06038.1 O61594 5CG0[A,B,C,D,E,F]
 β-glucosidase (Bgl1A) 3.2.1.21 pubmed
 Stachybotrys microspora AZK36092.1 A0A3Q8S5Z0  
 β-glucosidase (Bgl1B) 3.2.1.21 pubmed
 Stachybotrys microspora AZK36093.1 A0A3S5HJU9  
 β-1,2-glucosidase 1 (BGL-1; BGL1; Bgl) (fragment) 3.2.1.- pubmed
 Talaromyces amestolkiae CIB AKK32387.1    
 β-glucosidase (β-gly;Tmbgly) 3.2.1.21 pubmed
 Tenebrio molitor AAG26008.1 Q9GSE6  
 β-glucosidase (Tt_BG;THITE_2171046) 3.2.1.21 pubmed
 Thermothielavioides terrestris NRRL 8126 AEO69521.1 G2R9H7  
 β-1,4-glucosidase (Bgl2;ThBgl) 3.2.1.21 pubmed
 Trichoderma harzianum T7 ABN50090.1
ABN50091.1		 A0A0F9ZQA8
A0A2T4AR08
A3FPG4		 5BWF[A,B]
5JBK[A,B]
6EFU[A,B]
 β-glucosidase (Cel1b) (Cel1B) 3.2.1.21 pubmed
 Trichoderma reesei QM6A / QM9414 AAP57758.1
ABE22339.1
CBG21221.1		 G0RIF5
Q7Z9M2		 6KHT[A,B,C]
 β-glucosidase 2 (CEL1a;Bgl2;BGLII;BGL) (Cel1A) 3.2.1.21 pubmed
 Trichoderma reesei QM9414 BAA74959.1 O93785 3AHY[A,B,C,D]
 β-glucosidase 1 (non-cyanogenic) 3.2.1.21 pubmed
 Trifolium repens CAA40058.1
AAQ79767.1
CAW42889.1
CAW48592.1
CBC08417.1
CBD21385.1		 P26204  
 β-glucosidase 2 (cyanogenic) 3.2.1.21 pubmed
 Trifolium repens ABV54716.1
ABV54717.1
ABV54718.1
ABV54719.1
ABV54720.1
ABV54721.1
ABV54722.1
ABV54723.1
ABV54724.1
ABV54725.1
ABV54726.1
ABV54727.1
ABV54728.1
ABV54729.1
ABV54730.1
ABV54731.1
ABV54732.1
ABV54733.1
ABV54734.1
ABV54735.1
ABV54736.1
ABV54737.1
ABV54738.1
ABV54739.1
ABV54740.1
ABV54741.1
ABV54742.1
ABV54743.1
ABV54744.1
ABV54745.1
ABV54746.1
ABV54747.1
ABV54748.1
ABV54749.1
CAA40057.1		 A8C6G0
A8C6H2
A8C6J3
A8C6K7
A8C6L1
A8C6M3
P26205		 1CBG[A]
 β-glucosidase (Glu1B;TaGlu1b) 3.2.1.21
3.2.1.182		 pubmed
pubmed
 Triticum aestivum BAE92259.1
AEV76983.1		 J7F1W6
Q1XH05		 2DGA[A]
3AIQ[A]
3AIR[A]
3AIS[A]
 β-glucosidase (VmGlu2) 3.2.1.21   Valsa mali var. mali ANA91018.1    
 β-acuminosidase / furcatin hydrolase (FH) 3.2.1.161 pubmed
 Viburnum furcatum BAD14925.1 Q75W17  
 vicianin hydrolase (VH) 3.2.1.119 pubmed
 Vicia sativa subsp. nigra ABD03937.1 A2SY66  
 zeatin β-glucosidase (Glu1;p60.1;Zm-p60.1) 3.2.1.21 pubmed
 Zea mays CAA52293.1
CAM55487.1
CAM55549.1
CAW42858.1
CAW42907.1
CAW48561.1
CAW48562.1
CAW48610.1
CBC08386.1
CBC08387.1
CBD21354.1
CBD21355.1		 P49235
Q53WW9		 1HXJ[A,B]
 β-glucosidase 2 (Glu2) 3.2.1.21 pubmed
 Zea mays AAD09850.1
AEM17055.1
CAM55515.1
CAM55640.1
CAW42861.1
CAW42874.1
CAW48564.1
CAW48577.1
CBC08389.1
CBC08402.1
CBD21357.1
CBD21370.1		 G0YVY6
Q41761		  
 β-glucosidase 1 (Glu1) 3.2.1.21
3.2.1.182		 pubmed
pubmed
 Zea mays AAA65946.1
AAB03266.1
AAD10503.1
ACF82863.1
ACG32200.1
CAM55450.1
CAM55655.1
CAW42888.1
CAW48591.1
CBC08416.1
CBD21384.1		 P49235
Q53WW9		 1E1E[A,B]
1E1F[A,B]
1E4L[A,B]
1E4N[A,B]
1E55[A,B]
1E56[A,B]
1H49[A,B]
1V08[A,B]
unclassified
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-glucosidase 3.2.1.21 pubmed
 uncultured microorganism BAV69317.1 A0A1E1FFN6 5XGZ[A,B]
 6-phospho-β-glucosidase (Pbgl25-217) 3.2.1.86 pubmed
 uncultured organism AGD88872.1 L7Y2Z6  
 CelEx-SF309 3.2.1.21 doi
 uncultured organism AGK74983.1 N0CN28  
 β-glucosidase (Ambgl-lP) 3.2.1.21 pubmed
 unidentified SOU12973.1 A0A2I2LGB3 5WKA[A,B,C,D]
 β-glucosidase (Td2F2) 3.2.1.21 pubmed
 unidentified     3WH5[A]
3WH7[A]
3WH8[A]
5AYB[A]
5AYI[A]
3WH6[A]
 CR_5_Cow_Rumen 3.2.1.86 pubmed
 unidentified      
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