Glycoside Hydrolase Family 1

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-D-fucosidase (EC 3.2.1.38); phlorizin hydrolase (EC 3.2.1.62); exo-β-1,4-glucanase (EC 3.2.1.74); 6-phospho-β-galactosidase (EC 3.2.1.85); 6-phospho-β-glucosidase (EC 3.2.1.86); strictosidine β-glucosidase (EC 3.2.1.105); lactase (EC 3.2.1.108); amygdalin β-glucosidase (EC 3.2.1.117); prunasin β-glucosidase (EC 3.2.1.118); vicianin hydrolase (EC 3.2.1.119); raucaffricine β-glucosidase (EC 3.2.1.125); thioglucosidase (EC 3.2.1.147); β-primeverosidase (EC 3.2.1.149); isoflavonoid 7-O-β-apiosyl-β-glucosidase (EC 3.2.1.161); ABA-specific β-glucosidase (EC 3.2.1.175); DIMBOA β-glucosidase (EC 3.2.1.182); β-glycosidase (EC 3.2.1.-); hydroxyisourate hydrolase (EC 3.-.-.-); β-rutinosidase /α-L-rhamnose-(1,6)-β-D-glucosidase (EC 3.2.1.-); protodioscin 26-O-β-D-glucosidase (EC 3.2.1.186)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental); absent in plant myrosinases
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (54203); Uniprot accession (433); PDB accession (291); 3D entries (80); cryst (0)
| 1 | 2 | 3 | 4 |
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 amygdalin β-glucosidase I (AH I;AH1) 3.2.1.117 pubmed
Prunus serotina AAA93234.2
AAL07489.1
CAW42871.1
CAW48574.1
CBC08399.1
CBD21367.1
P29259
P29260
P29261
P29262
Q40984
Q945G7
 
 myrosinase (RMB2) 3.2.1.147 pubmed
Raphanus sativus BAB17227.1 Q9FXR0  
 myrosinase (RMB1) 3.2.1.147 pubmed
Raphanus sativus BAB17226.1 Q9FXR1  
 β-glucosidase 1 (Bg1;BglI;BGIV) 3.2.1.21 pubmed
Rasamsonia emersonii CBS 814.70 AAL34084.2
AAL89551.1
Q8X214  
 strictosidine β-glucosidase (Sgr1;SG) 3.2.1.105 pubmed
Rauvolfia serpentina CAC83098.1
CBG21226.1
Q8GU20 2JF6[A,B]
2JF7[A,B]
3ZJ7[A,B]
3ZJ8[A,B]
 raucaffricine O-β-glucosidase (RG) 3.2.1.125 pubmed
Rauvolfia serpentina AAF03675.1 Q9SPP9 3U57[A,B]
3U5U[A,B]
3U5Y[A,B]
3ZJ6[A,B]
4A3Y[A,B]
4ATD[A,B]
4ATL[A,B]
4EK7[A,B]
 β-glucosidase (BGluc-1;RfBGluc-1) 3.2.1.21
3.2.1.37
3.2.1.38
pubmed
pubmed
pubmed
Reticulitermes flavipes ADK12988.1 D9ILU1  
 male-specific β-glycosidase (Lmα-p72) 3.2.1.23 pubmed
Rhyparobia maderae AAL40863.1 Q8WQL9  
 β-glucosidase (ScGlu) (plastidic) 3.2.1.21
3.2.1.182
doi
doi
Secale cereale AAG00614.1
CAW42885.1
CAW48588.1
CBC08413.1
CBD21381.1
CBG21237.1
Q9FYS3 3AIU[A]
3AIV[A]
3AIW[A]
 β-glucosidase, partial (fragment) 3.2.1.21 pubmed
Sicyos edulis QIA00482.1 A0A6C0R7S1  
 myrosinase 3.2.1.147 pubmed
Sinapis alba CAA42533.1 P29736
Q7SIB0
1DWA[M]
1DWF[M]
1DWG[M]
1DWH[M]
1DWI[M]
1DWJ[M]
1E4M[M]
1E6Q[M]
1E6S[M]
1E6X[M]
1E70[M]
1E71[M]
1E72[M]
1E73[M]
1MYR[A]
1W9B[M]
1W9D[M]
2MYR[A]
2WXD[M]
 β-mannosidase (LeMside 2) 3.2.1.25 pubmed
Solanum lycopersicum AAL37719.1
AAL37714.1
CBD28478.1
Q8VWL8  
 cyanogenic β-glucosidase (dhurrinase-2) 3.2.1.21 doi
Sorghum bicolor AAK49119.1
CAW42882.1
CAW48585.1
CBC08410.1
CBD21378.1
CBG21230.1
Q93XR2  
 cyanogenic β-glucosidase / dhurrinase 1 (Dhr1) 3.2.1.21 pubmed
Sorghum bicolor P721N AAC49177.1
CAW42873.1
CAW48576.1
CBC08401.1
CBD21369.1
CBG21205.1
Q41290 1V02[A,B,C,D,F]
1V03[A]
 β-glycosidase (β-gly;Sfbgly) 3.2.1.21
3.2.1.23
3.2.1.38
pubmed
pubmed
pubmed
Spodoptera frugiperda AAC06038.1 O61594 5CG0[A,B,C,D,E,F]
 β-glucosidase (Bgl1A) 3.2.1.21 pubmed
Stachybotrys microspora AZK36092.1 A0A3Q8S5Z0  
 β-glucosidase (Bgl1B) 3.2.1.21 pubmed
Stachybotrys microspora AZK36093.1 A0A3S5HJU9  
 β-1,2-glucosidase 1 (BGL-1; BGL1; Bgl) (fragment) 3.2.1.- pubmed
Talaromyces amestolkiae CIB AKK32387.1    
 β-glucosidase (β-gly;Tmbgly) 3.2.1.21 pubmed
Tenebrio molitor AAG26008.1 Q9GSE6  
 β-glucosidase (Tt_BG;THITE_2171046) 3.2.1.21 pubmed
Thermothielavioides terrestris NRRL 8126 AEO69521.1 G2R9H7  
 β-1,4-glucosidase (Bgl2;ThBgl) 3.2.1.21 pubmed
Trichoderma harzianum T7 ABN50090.1
ABN50091.1
A0A0F9ZQA8
A0A2T4AR08
A3FPG4
5BWF[A,B]
5JBK[A,B]
6EFU[A,B]
 β-glucosidase (Cel1b) (Cel1B) 3.2.1.21 pubmed
Trichoderma reesei QM6A / QM9414 AAP57758.1
ABE22339.1
CBG21221.1
G0RIF5
Q7Z9M2
6KHT[A,B,C]
 β-glucosidase 2 (CEL1a;Bgl2;BGLII;BGL) (Cel1A) 3.2.1.21 pubmed
Trichoderma reesei QM9414 BAA74959.1 O93785 3AHY[A,B,C,D]
 β-glucosidase 1 (non-cyanogenic) 3.2.1.21 pubmed
Trifolium repens CAA40058.1
AAQ79767.1
CAW42889.1
CAW48592.1
CBC08417.1
CBD21385.1
P26204  
 β-glucosidase 2 (cyanogenic) 3.2.1.21 pubmed
Trifolium repens ABV54716.1
ABV54717.1
ABV54718.1
ABV54719.1
ABV54720.1
ABV54721.1
ABV54722.1
ABV54723.1
ABV54724.1
ABV54725.1
ABV54726.1
ABV54727.1
ABV54728.1
ABV54729.1
ABV54730.1
ABV54731.1
ABV54732.1
ABV54733.1
ABV54734.1
ABV54735.1
ABV54736.1
ABV54737.1
ABV54738.1
ABV54739.1
ABV54740.1
ABV54741.1
ABV54742.1
ABV54743.1
ABV54744.1
ABV54745.1
ABV54746.1
ABV54747.1
ABV54748.1
ABV54749.1
CAA40057.1
A8C6G0
A8C6H2
A8C6J3
A8C6K7
A8C6L1
A8C6M3
P26205
1CBG[A]
 β-glucosidase (Glu1B;TaGlu1b) 3.2.1.21
3.2.1.182
pubmed
pubmed
Triticum aestivum BAE92259.1
AEV76983.1
J7F1W6
Q1XH05
2DGA[A]
3AIQ[A]
3AIR[A]
3AIS[A]
 β-glucosidase (VmGlu2) 3.2.1.21   Valsa mali var. mali ANA91018.1    
 β-acuminosidase / furcatin hydrolase (FH) 3.2.1.161 pubmed
Viburnum furcatum BAD14925.1 Q75W17  
 vicianin hydrolase (VH) 3.2.1.119 pubmed
Vicia sativa subsp. nigra ABD03937.1 A2SY66  
 zeatin β-glucosidase (Glu1;p60.1;Zm-p60.1) 3.2.1.21 pubmed
Zea mays CAA52293.1
CAM55487.1
CAM55549.1
CAW42858.1
CAW42907.1
CAW48561.1
CAW48562.1
CAW48610.1
CBC08386.1
CBC08387.1
CBD21354.1
CBD21355.1
P49235
Q53WW9
1HXJ[A,B]
 β-glucosidase 2 (Glu2) 3.2.1.21 pubmed
Zea mays AAD09850.1
AEM17055.1
CAM55515.1
CAM55640.1
CAW42861.1
CAW42874.1
CAW48564.1
CAW48577.1
CBC08389.1
CBC08402.1
CBD21357.1
CBD21370.1
G0YVY6
Q41761
 
 β-glucosidase 1 (Glu1) 3.2.1.21
3.2.1.182
pubmed
pubmed
Zea mays AAA65946.1
AAB03266.1
AAD10503.1
ACF82863.1
ACG32200.1
CAM55450.1
CAM55655.1
CAW42888.1
CAW48591.1
CBC08416.1
CBD21384.1
P49235
Q53WW9
1E1E[A,B]
1E1F[A,B]
1E4L[A,B]
1E4N[A,B]
1E55[A,B]
1E56[A,B]
1H49[A,B]
1V08[A,B]
unclassified
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-glucosidase 3.2.1.21 pubmed
uncultured microorganism BAV69317.1 A0A1E1FFN6 5XGZ[A,B]
 6-phospho-β-glucosidase (Pbgl25-217) 3.2.1.86 pubmed
uncultured organism AGD88872.1 L7Y2Z6  
 CelEx-SF309 3.2.1.21 doi
uncultured organism AGK74983.1 N0CN28  
 β-glucosidase (Ambgl-lP) 3.2.1.21 pubmed
unidentified SOU12973.1 A0A2I2LGB3 5WKA[A,B,C,D]
 β-glucosidase (Td2F2) 3.2.1.21 pubmed
unidentified     3WH5[A]
3WH7[A]
3WH8[A]
5AYB[A]
5AYI[A]
3WH6[A]
 CR_5_Cow_Rumen 3.2.1.86 pubmed
unidentified      
Top


Last update: 2022-07-07 © Copyright 1998-2022
AFMB - CNRS - Université d'Aix-Marseille