Glycoside Hydrolase Family 1

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-galactosidase (EC 3.2.1.23); β-mannosidase (EC 3.2.1.25); β-glucuronidase (EC 3.2.1.31); β-xylosidase (EC 3.2.1.37); β-D-fucosidase (EC 3.2.1.38); phlorizin hydrolase (EC 3.2.1.62); exo-β-1,4-glucanase (EC 3.2.1.74); 6-phospho-β-galactosidase (EC 3.2.1.85); 6-phospho-β-glucosidase (EC 3.2.1.86); strictosidine β-glucosidase (EC 3.2.1.105); lactase (EC 3.2.1.108); amygdalin β-glucosidase (EC 3.2.1.117); prunasin β-glucosidase (EC 3.2.1.118); vicianin hydrolase (EC 3.2.1.119); raucaffricine β-glucosidase (EC 3.2.1.125); thioglucosidase (EC 3.2.1.147); β-primeverosidase (EC 3.2.1.149); isoflavonoid 7-O-β-apiosyl-β-glucosidase (EC 3.2.1.161); ABA-specific β-glucosidase (EC 3.2.1.175); DIMBOA β-glucosidase (EC 3.2.1.182); β-glycosidase (EC 3.2.1.-); hydroxyisourate hydrolase (EC 3.-.-.-)
Mechanism Retaining
ClanGH-A
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental); absent in plant myrosinases
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (18739); Uniprot accession (2276); PDB accession (243); 3D entries (53); cryst (0)
All (16723) Archaea (143) Bacteria (15512) Eukaryota (1026) Viruses (1) unclassified (41) Structure (53) Characterized (336)
| 1 | 2 |
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Ahos_0285   Acidianus hospitalis W1 AEE93176.1    
 B6F84_04960   Acidianus manzaensis YN-25 ARM75441.1    
 B6F84_03570   Acidianus manzaensis YN-25 ARM75201.1    
 β-glycosidase (β-Gly;As?-Gly;ASAC_1390) 3.2.1.- Acidilobus saccharovorans 345-15 ADL19795.1 D9PZ08 4HA3[A]
4HA4[A]
 SE86_03625   Acidilobus sp. 7A AMD30575.1    
 Aboo_0529   Aciduliprofundum boonei T469 ADD08340.1 B5IA26  
 Cmaq_0408 3.2.1.21 Caldivirga maquilingensis IC-167 ABW01253.1 A8MBR0  
 Cmaq_0652 3.2.1.21 Caldivirga maquilingensis IC-167 ABW01492.1 A8MCI6  
 Cmaq_1537   Caldivirga maquilingensis IC-167 ABW02360.1 A8M9E1  
 Nps_01800   Candidatus Nanopusillus acidilobi 7A AMD29807.1    
 CPM_0938   Cuniculiplasma divulgatum PM4 (=JCM 30641; =VKM B-2940) SJK84780.1    
 CPM_1620   Cuniculiplasma divulgatum PM4 (=JCM 30641; =VKM B-2940) SJK85407.1    
 CPM_0129   Cuniculiplasma divulgatum PM4 (=JCM 30641; =VKM B-2940) SJK84024.1    
 CSP5_0154   Cuniculiplasma divulgatum S5(T) (=JCM 30642; =VKM B-2941) SIM33300.1    
 CSP5_0942   Cuniculiplasma divulgatum S5(T) (=JCM 30642; =VKM B-2941) SIM59545.1    
 CSP5_1651   Cuniculiplasma divulgatum S5(T) (=JCM 30642; =VKM B-2941) SIM79973.1    
 DKAM_0253 (fragment)   Desulfurococcus amylolyticus 1221n ACL10579.1 B8D332  
 Desfe_0624   Desulfurococcus amylolyticus DSM 16532 AFL66525.1    
 Sequence 15 from patent US 6368844   Desulfurococcus sp. CAH68683.1
CAT81435.1
   
 FACI_IFERC00001G0136   Ferroplasma acidarmanus fer1 AGO60116.1    
 FACI_IFERC00001G1310   Ferroplasma acidarmanus fer1 AGO61290.1    
 FAD_0324   Ferroplasma acidiphilum Y ARD84246.1    
 Igag_0909   Ignisphaera aggregans DSM 17230 ADM27725.1 E0STV9  
 Igag_0940   Ignisphaera aggregans DSM 17230 ADM27756.1 E0STZ0  
 PAP_04145   Palaeococcus pacificus DY20341 AIF69244.1    
 PTO1259   Picrophilus torridus DSM 9790 AAT43844.1 Q6KZK8  
 PTO1453   Picrophilus torridus DSM 9790 AAT44038.1 Q6KZ14  
 PAE1736 (possible fragment)   Pyrobaculum aerophilum str. IM2 AAL63693.1
NP_559511.1
Q8ZWK9  
 Pars_0741   Pyrobaculum arsenaticum DSM 13514 ABP50327.1 A4WIW0  
 Pcal_0630   Pyrobaculum calidifontis JCM 11548 ABO08056.1 A3MTT9  
 P186_0066   Pyrobaculum ferrireducens 1860 AET31535.1    
 Pisl_1708   Pyrobaculum islandicum DSM 4184 ABL88859.1 A1RV77  
 Tneu_0727   Pyrobaculum neutrophilum V24Sta ACB39666.1 B1YD03  
 Pogu_1602   Pyrobaculum oguniense TE7 AFA39629.1    
 PYWP30_00777 (fragment)   Pyrobaculum sp. WP30 AKT34419.1    
 PAB1740 (BmnA)   Pyrococcus abyssi GE5 CAB49848.1
NP_126617.1
Q9V058  
 PAB2376 (Bgal;BglB)   Pyrococcus abyssi GE5 CAB50447.1
NP_127217.1
Q9UYG5  
 β-galactosidase (CelB) 3.2.1.23 Pyrococcus furiosus B232 AHW49177.1    
 PFC_01325   Pyrococcus furiosus COM1 AFN03236.1    
 PFC_00985   Pyrococcus furiosus COM1 AFN03170.1    
 PFC_05250   Pyrococcus furiosus COM1 AFN03997.1    
 PFC_07835 (fragment)   Pyrococcus furiosus COM1 AFN04501.1    
 PFC_03860 (short fragment)   Pyrococcus furiosus COM1 AFN03721.1    
 β-mannosidase (BglB;PF0356) 3.2.1.25 Pyrococcus furiosus DSM 3638 AAL80480.1
NP_578085.1
Q8U3U9  
 β-glucosidase / β-glycosidase / β-rutinosidase (Cel1A;CelB;BGLPf;PfBgl1;PFTG;PF0073;Pf-β-gly) 3.2.1.21
3.2.1.-
Pyrococcus furiosus DSM 3638 AAL80197.1
AAC25555.1
ABC06396.1
NP_577802.1
E7FHY4
Q51723
3APG[A,B,C,D]
3WDP[P,Q,R,S]
3WQ8[A,B,C,D,E,F,G,H,I,J,K,L]
 β-mannosidase / β-galactosidase (BmnA;PF1208) 3.2.1.23
3.2.1.25
Pyrococcus furiosus DSM 3638 AAL81332.1
AAC44387.1
AAM56789.1
ABC06395.1
CAH68690.1
CAT81449.1
NP_578937.1
E7FHC0
Q51733
 
 β-glucosidase (BglA;PF0442) (Cel1B) 3.2.1.21 Pyrococcus furiosus DSM 3638 AAL80566.1
AAG28457.1
NP_578171.1
E7FI48
Q9HHB3
 
 alkyl β-glucosidase (membrane-bound) (BGPh;BglA;PH0366) 3.2.1.21 Pyrococcus horikoshii OT3 BAA29440.1
ABC06393.1
NP_142340.1
O58104 1VFF[A]
 β-mannosidase (BglB;PH0501) 3.2.1.25 Pyrococcus horikoshii OT3 BAA29589.1
ABC06394.1
NP_142473.1
O58237  
 TQ32_01545   Pyrococcus kukulkanii NCB100 AMM53326.1    
 Py04_0550   Pyrococcus sp. ST04 AFK22152.1    
 β-galactosidase 3.2.1.23 Pyrococcus woesei AAB97862.1 O52629  
 Shell_1057   Staphylothermus hellenicus DSM 12710 ADI32161.1 D7D8R5  
 Shell_0804   Staphylothermus hellenicus DSM 12710 ADI31917.1 D7D821  
 Smar_1391   Staphylothermus marinus F1 ABN70482.1
AAM56784.1
CAH68685.1
CAT81439.1
A3DPC2  
 β-glycosidase (BgaS;Saci_1849) 3.2.1.- Sulfolobus acidocaldarius DSM 639 AAY81155.1
YP_256448.1
P14288  
 SacN8_09030   Sulfolobus acidocaldarius N8 AGE71766.1    
 SacRon12I_09050   Sulfolobus acidocaldarius Ron12/I AGE74039.1    
 SUSAZ_08905   Sulfolobus acidocaldarius SUSAZ AHC52032.1    
 SiH_2277   Sulfolobus islandicus HVE10/4 ADX83617.1    
 LD85_2633   Sulfolobus islandicus L.D.8.5 ADB88250.1 D2PGB0  
 LS215_2510   Sulfolobus islandicus L.S.2.15 ACP36466.1 C3ML64  
 SiL_2186   Sulfolobus islandicus LAL14/1 AGJ63624.1    
 M1425_2338   Sulfolobus islandicus M.14.25 ACP39066.1 C3MSC3  
 M1627_2417   Sulfolobus islandicus M.16.27 ACP56269.1 C3N1P2  
 M164_2345   Sulfolobus islandicus M.16.4 ACR42944.1 C4KL63  
 LacS   Sulfolobus islandicus REN1H1 ABY78030.1 B1P2F7  
 SiRe_2224   Sulfolobus islandicus REY15A ADX86277.1    
 YG5714_2480   Sulfolobus islandicus Y.G.57.14 ACP46718.1 C3NAC5  
 YN1551_0427   Sulfolobus islandicus Y.N.15.51 ACP47593.1 C3NL79  
 β-glycosidase (Bgly;SSG) 3.2.1.- Sulfolobus shibatae AAA79030.1 P50388  
 β-glycosidase (LacS;Ssol98_010100014373) 3.2.1.21
3.2.1.23
Sulfolobus solfataricus 98/2 AAD21094.1
AET42942.1
G8GCT7  
 SULC_0798   Sulfolobus solfataricus 98/2 SULC AKA75868.1    
 β-glycosidase / β-galactosidase 3.2.1.- Sulfolobus solfataricus DSM1616 CAA34074.1 P14288  
 SSOP1_3114   Sulfolobus solfataricus P1 SAI86668.1    
 β-glycosidase S (LacS;Ss-β-gly;SSO3019) 3.2.1.21
3.2.1.23
3.2.1.-
Sulfolobus solfataricus P2 AAA72843.1
AAE29896.1
AAK43121.1
ABC06397.1
ACW34039.1
CAC24042.1
CAJ18790.1
NP_344331.1
P22498 1GOW[A,B]
1UWI[A,B,C,D]
1UWQ[A,B]
1UWR[A,B]
1UWS[A,B]
1UWT[A,B]
1UWU[A,B]
2CEQ[A,B]
2CER[A,B]
4EAM[A,B]
4EAN[A,B]
5I3D[A,B,C,D]
5IXE[A,B]
 SULA_0798   Sulfolobus solfataricus SULA AKA78560.1    
 SULB_0800   Sulfolobus solfataricus SULB AKA73170.1    
 BFU36_07165   Sulfolobus sp. A20 AOL16512.1    
 ST0773   Sulfolobus tokodaii str. 7 BAB65785.1
NP_376676.1
Q973X5  
 Sequence 20 from patent US 6368844   Thermococcus alcaliphilus CAH68688.1
AAM56787.1
CAT81445.1
   
 TBCH5v1_1155   Thermococcus barophilus CH5 ALM75089.1    
 TERMP_00966   Thermococcus barophilus MP ADT83942.1    
 A3L01_07405   Thermococcus barossii SHCK-94 ASJ05205.1    
 A3L01_09460   Thermococcus barossii SHCK-94 ASJ05578.1    
 A3L02_03385   Thermococcus celer Vu 13 ASI98671.1    
 A3L02_03345   Thermococcus celer Vu 13 ASI98663.1    
 β-mannanase (63GB1)   Thermococcus chitonophagus CAH68694.1
AAM56793.1
ACM94264.1
CAT81457.1
   
 CHITON_0577   Thermococcus chitonophagus DSM 10152 CUX77356.1    
 CHITON_2151   Thermococcus chitonophagus DSM 10152 CUX78930.1
AAM56788.1
CAH68689.1
CAT81447.1
   
 A3L04_02920   Thermococcus chitonophagus GC74 ASJ16103.1    
 A3L04_00020 (fragment)   Thermococcus chitonophagus GC74 ASJ17527.1    
 TEU_03570   Thermococcus eurythermalis A501 AIU69500.1    
 A3K92_03780   Thermococcus gorgonarius W-12 ASJ00654.1    
 A3K92_03745   Thermococcus gorgonarius W-12 ASJ00648.1    
 X802_02925   Thermococcus guaymasensis DSM 11113 AJC71232.1    
 X802_02965   Thermococcus guaymasensis DSM 11113 AJC71239.1    
 β-glycosidase (TK1827) 3.2.1.- Thermococcus kodakarensis KOD1 BAD86016.1
CAT70991.1
Q5JDV2  
 β-glycosidase (Tk?gly;TK1761) 3.2.1.- Thermococcus kodakarensis KOD1 BAA78713.1
BAD85950.1
CAT70557.1
Q9YGB8  
 OCC_04445   Thermococcus litoralis DSM 5473 EHR78077.1    
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