Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (14617); Uniprot accession (3282); PDB accession (301); 3D entries (77); cryst (4)
All (13074) Archaea (61) Bacteria (9464) Eukaryota (3057) Viruses (255) unclassified (237) Structure (77 - 4 cryst) Characterized (477)
| 1 | 2 | 3 |
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 ORF41   Helicoverpa armigera NPV NNg1 BAG74606.1 B5X036  
 Orf40   Helicoverpa armigera NPV strain Australia AEN03965.1    
 chitinase   Helicoverpa armigera nucleopolyhedrovirus AAM78589.1 Q8JMJ8  
 chitinase 3.2.1.14 Helicoverpa armigera nucleopolyhedrovirus AAD22958.1 Q9WFU7  
 chitinase 3.2.1.14 Helicoverpa armigera nucleopolyhedrovirus AAK96293.1
AAK28347.1
NP_203597.1
Q91BX5
Q995W8
 
 HanGV4gp041   Helicoverpa armigera nucleopolyhedrovirus G4 AAK56504.1
AAG53784.1
NP_075110.1
Q99H06  
 chitinase   Helicoverpa armigera nucleopolyhedrovirus L1 ALD88488.1    
 ORF-39   Helicoverpa armigera nucleopolyhedrovirus LB1 AJP07193.1    
 ORF-39   Helicoverpa armigera nucleopolyhedrovirus LB3 AJP07328.1    
 ORF-39   Helicoverpa armigera nucleopolyhedrovirus LB6 AJP07463.1    
 ORF-39   Helicoverpa armigera nucleopolyhedrovirus SP1A AJP07598.1    
 ORF-39   Helicoverpa armigera nucleopolyhedrovirus SP1B AJP07734.1    
 HaSNPV-H25EA1_041   Helicoverpa armigera SNPV AIG63220.1    
 HaSNPV-AC53_041   Helicoverpa SNPV AC53 AIG63083.1    
 chitinase   Helicoverpa SNPV AC53 AC53C1 AMN15222.1    
 chitinase   Helicoverpa SNPV AC53 AC53C3 AMN15360.1    
 chitinase   Helicoverpa SNPV AC53 AC53C5 AMN15498.1    
 chitinase   Helicoverpa SNPV AC53 AC53C6 AMN15636.1    
 chitinase   Helicoverpa SNPV AC53 AC53C9 AMN15774.1    
 chitinase   Helicoverpa SNPV AC53 AC53T2 AMN15912.1    
 chitinase   Helicoverpa SNPV AC53 AC53T4.1 AMN16050.1    
 chitinase   Helicoverpa SNPV AC53 AC53T4.2 AMN16188.1    
 chitinase   Helicoverpa SNPV AC53 AC53T5 AMN16326.1    
 Chitinase   Helicoverpa zea single nucleopolyhedrovirus AKN50534.1    
 ORF41   Helicoverpa zea single nucleopolyhedrovirus AAL56186.1    
 chitinase   Helicoverpa zea single nucleopolyhedrovirus AAB54004.1 O10621  
 HzsnnVgp041   Helicoverpa zea single nucleopolyhedrovirus HS-18 AHN05416.1
NP_542664.1
Q8V5U9  
 Hesp058   Hemileuca sp. nucleopolyhedrovirus AGR56810.1    
 chitinase (ChiA) 3.2.1.14 Hyphantria cunea nucleopolyhedrovirus AAD31762.1
BAE72319.1
Q9WGG2  
 IIV22A_084R   Invertebrate iridescent virus 22 CCV01928.1    
 IIV30_086R   Invertebrate iridescent virus 30 CCV02281.1    
 IIV22_080R   Invertebrate iridovirus 22 CCV01757.1    
 IIV25_085R   Invertebrate iridovirus 25 CCV02103.1    
 chitinase   Lambdina fiscellaria nucleopolyhedrovirus AKC91706.1    
 chitA   Leucania separata nuclear polyhedrosis virus AH1 AAR28821.1 Q0IL62  
 chitinase   Lymantria dispar multiple nucleopolyhedrovirus ANS70953.1    
 chitinase   Lymantria dispar multiple nucleopolyhedrovirus AOW42762.1    
 chitinase   Lymantria dispar multiple nucleopolyhedrovirus AMO65560.1    
 chitinase (v-ChiA;LdOrf-70;LdnVgp071)   Lymantria dispar multiple nucleopolyhedrovirus AAC70256.1
NP_047707.1
Q9YMQ7  
 chitinase   Lymantria dispar multiple nucleopolyhedrovirus AHC69568.1    
 chitinase   Lymantria dispar multiple nucleopolyhedrovirus AJR20344.1
AQQ80090.1
   
 ChiA; chitinase   Lymantria dispar multiple nucleopolyhedrovirus 3029 AIX47908.1    
 Chitinase   Lymantria dispar multiple nucleopolyhedrovirus 3041 AMO27740.1    
 Chitinase   Lymantria dispar multiple nucleopolyhedrovirus 3054 AMO27568.1    
 Chitinase   Lymantria dispar multiple nucleopolyhedrovirus Ab-a624 AMO27924.1    
 chitinase   Lymantria xylina MNPV ADD73775.1 D4N2A3  
 chitinase   Malacosoma sp. alphabaculovirus ANW09681.1    
 chitinase (Masp6.2)   Malacosoma sp. alphabaculovirus 164 ANW12332.1    
 v-chiA   Mamestra brassicae multiple nucleopolyhedrovirus AIL25096.1    
 Mb_orf19   Mamestra brassicae multiple nucleopolyhedrovirus CHb1 AFP95738.1    
 MabrNPVgp018   Mamestra brassicae multiple nucleopolyhedrovirus K1 AFL64869.1    
 ORF 22 (Chit)   Mamestra configurata nucleopolyhedrovirus A AAQ11041.1
AAM09130.1
NP_613105.1
Q8QLL2  
 Chit   Mamestra configurata nucleopolyhedrovirus B AAM95006.1
NP_689194.1
Q8JMD3  
 chitinase   Maruca vitrata MNPV ABL76047.1 A1YRF7  
 SAGO17_0013   Mimivirus AB-566-O17 ARR74933.1    
 Os5_119R   Only Syngen Nebraska virus 5 APC25632.1    
 Os5_117L   Only Syngen Nebraska virus 5 APC25630.1    
 chitinase (ChiA)   Orgyia ericae nucleopolyhedrovirus AAR90602.1 Q6R8F1  
 chitinase   Orgyia leucostigma nucleopolyhedrovirus ABY65750.1 B0FDP2  
 chitinase (ORF124)   Orgyia pseudotsugata multiple nucleopolyhedrovirus AAC59123.1
NP_046280.1
O10363  
 chitinase (A260R;PBCV1_A260R) 3.2.1.14 Paramecium bursaria Chlorella virus 1 AAC96628.1
AAC96628.3
AAC97066.2
NP_048613.1
O41019
Q84577
 
 endochitinase (A181/182R;PBCV1_A181/182R) 3.2.1.14 Paramecium bursaria Chlorella virus 1 AAC96549.2
AAC96549.3
NP_048529.1
Q84501  
 endochitinase (A181/182R;PBCV1_A181/182R) 3.2.1.14 Paramecium bursaria Chlorella virus 1 AAC96549.2
AAC96549.3
NP_048529.1
Q84501  
 PBCVAN69C_204R   Paramecium bursaria Chlorella virus AN69C AGE48399.1    
 PBCVAN69C_204R   Paramecium bursaria Chlorella virus AN69C AGE48399.1    
 PBCVAN69C_297R   Paramecium bursaria Chlorella virus AN69C AGE48437.1    
 PBCVAP110A_942R   Paramecium bursaria Chlorella virus AP110A AGE48989.1    
 PBCVAP110A_106R   Paramecium bursaria Chlorella virus AP110A AGE48698.1    
 AR158_C220R   Paramecium bursaria Chlorella virus AR158 ABU43766.1 A7RB24  
 AR158_C220R   Paramecium bursaria Chlorella virus AR158 ABU43766.1 A7RB24  
 PBCVCan184_944R (Can18-4_944R)   Paramecium bursaria Chlorella virus Can18-4 AGE50008.1    
 PBCVCan184_113R (Can18-4_113R)   Paramecium bursaria Chlorella virus Can18-4 AGE49710.1    
 PBCVCVA1_942R (Cvα-1_942R)   Paramecium bursaria Chlorella virus CVA-1 AGE50671.1    
 PBCVCVA1_102R (Cvα-1_102R)   Paramecium bursaria Chlorella virus CVA-1 AGE50385.1    
 PBCVCVB1_890R (Cvβ-1_890R)   Paramecium bursaria Chlorella virus CVB-1 AGE51009.1    
 PBCVCVB1_129R (Cvβ-1_129R)   Paramecium bursaria Chlorella virus CVB-1 AGE50730.1    
 PBCVCVG1_896R (Cvg-1_896R)   Paramecium bursaria Chlorella virus CVG-1 AGE51335.1    
 PBCVCVG1_105R (Cvg-1_105R)   Paramecium bursaria Chlorella virus CVG-1 AGE51059.1    
 PBCVCviKI_194R   Paramecium bursaria Chlorella virus CviKI AGE51440.1    
 PBCVCviKI_194R   Paramecium bursaria Chlorella virus CviKI AGE51440.1    
 chitinase (vChti-1) 3.2.1.14 Paramecium bursaria Chlorella virus CVK2 BAA78554.1 Q9WAX4  
 chitinase (vChti-1) 3.2.1.14 Paramecium bursaria Chlorella virus CVK2 BAA78554.1 Q9WAX4  
 PBCVCVM1_927R (Cvm-1_927R)   Paramecium bursaria Chlorella virus CVM-1 AGE52009.1    
 PBCVCVM1_122R (Cvm-1_122R)   Paramecium bursaria Chlorella virus CVM-1 AGE51723.1    
 PBCVCVR1_948R (Cvr-1_948R)   Paramecium bursaria Chlorella virus CVR-1 AGE52349.1    
 PBCVCVR1_109R (Cvr-1_109R)   Paramecium bursaria Chlorella virus CVR-1 AGE52062.1    
 PBCVCvsA1_200R   Paramecium bursaria Chlorella virus CvsA1 AGE52455.1    
 PBCVCvsA1_200R   Paramecium bursaria Chlorella virus CvsA1 AGE52455.1    
 PBCVCZ2_902R (Cz-2_902R)   Paramecium bursaria Chlorella virus CZ-2 AGE53016.1    
 PBCVCZ2_070R (Cz-2_070R)   Paramecium bursaria Chlorella virus CZ-2 AGE52727.1    
 FR483_N779R   Paramecium bursaria Chlorella virus FR483 ABT16064.1 A7J8D3  
 FR483_N779R   Paramecium bursaria Chlorella virus FR483 ABT16064.1 A7J8D3  
 PBCVFr5L_897R   Paramecium bursaria Chlorella virus Fr5L AGE53360.1    
 PBCVFr5L_098R   Paramecium bursaria Chlorella virus Fr5L AGE53069.1    
 PBCVIL3A_196R (Il-3a_196R)   Paramecium bursaria Chlorella virus IL-3A AGE53811.1    
 PBCVIL3A_196R (Il-3a_196R)   Paramecium bursaria Chlorella virus IL-3A AGE53811.1    
 PBCVIL3A_285R (Il-3a_285R)   Paramecium bursaria Chlorella virus IL-3A AGE53845.1    
 PBCVIL52s1_262R (Il-5-2s1_262R)   Paramecium bursaria Chlorella virus IL-5-2s1 AGE54161.1    
 PBCVIL52s1_262R (Il-5-2s1_262R)   Paramecium bursaria Chlorella virus IL-5-2s1 AGE54161.1    
 PBCVIL52s1_373R (Il-5-2s1_373R)   Paramecium bursaria Chlorella virus IL-5-2s1 AGE54203.1    
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