Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (14935); Uniprot accession (3282); PDB accession (301); 3D entries (77); cryst (4)
All (13391) Archaea (61) Bacteria (9754) Eukaryota (3083) Viruses (256) unclassified (237) Structure (77 - 4 cryst) Characterized (477)
| 1 | ... | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | ... | 31 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 tandem of 4 chitinases   Drosophila melanogaster AAX33520.1
AAB81858.1
AAF45396.1
AAM50881.1
AGB93232.1
AGB93233.1
EAA46011.1
Q8MS85
Q9W5U2
 
 tandem of 4 chitinases   Drosophila melanogaster AAX33520.1
AAF45397.1
AAM50881.1
AGB93232.1
AGB93233.1
EAA46011.1
Q8MS85
Q9W5U2
 
 CG3044   Drosophila melanogaster AAF46212.1
AAM49996.1
NP_572361.1
Q9W3V1  
 CG2989   Drosophila melanogaster AAF46544.1
AAF46544.2
AAF46544.3
ABW09380.1
ABW09380.2
AFH07312.1
AFH07313.1
AFH07314.1
AFH07315.1
AFH07316.1
NP_572598.1
Q9W2Z3  
 CG9357   Drosophila melanogaster AAF46663.2
AAF46663.1
AAM50644.1
NP_611542.1
Q8MSI4
Q9W2M7
 
 CG10531 (Cht9)   Drosophila melanogaster AAF46665.3
AAL39889.1
AAL39889.2
NP_611543.2
Q7YXW0
Q9W2M5
 
 CG1869 (Cht7)   Drosophila melanogaster AAK93412.1
AAF47714.2
AAF47714.3
NP_647768.2
Q9VZV2  
 CG1869 (Cht7)   Drosophila melanogaster AAK93412.1
AAF47714.2
AAF47714.3
NP_647768.2
Q9VZV2  
 CG9307 (Cht5)   Drosophila melanogaster AAF54987.1
AAL29101.1
NP_650314.1
Q9VFR3  
 CG5154 (Cht14)   Drosophila melanogaster AAF57703.1
AAF57703.2
AAL39252.1
AAS93772.1
NP_611321.2
B5RJG0
Q8T0R7
Q8T0R7
 
 CG5210   Drosophila melanogaster ZBMEL131 CBA35212.1 E1UIC9
Q23997
 
 CG5154   Drosophila melanogaster ZBMEL145 CBA35203.1 E1UIC0  
 CG5154   Drosophila melanogaster ZBMEL157 CBA35204.1 E1UIC1  
 CG5210   Drosophila melanogaster ZBMEL157 CBA35213.1 E1UID0
Q23997
 
 CG5154   Drosophila melanogaster ZBMEL191 CBA35205.1 E1UIC2  
 CG5154   Drosophila melanogaster ZBMEL229 CBA35206.1 E1UIC3  
 CG5210   Drosophila melanogaster ZBMEL229 CBA35216.1 E1UID3
Q23997
 
 CG5154   Drosophila melanogaster ZBMEL377 CBA35207.1 E1UIC4  
 CG5210   Drosophila melanogaster ZBMEL377 CBA35217.1 E1UID4
Q23997
 
 CG5154   Drosophila melanogaster ZBMEL384 CBA35208.1 E1UIC5  
 CG5154   Drosophila melanogaster ZBMEL398 CBA35209.1 E1UIC6  
 CG5154   Drosophila melanogaster ZBMEL82 CBA35201.1 E1UIB8  
 CG5154   Drosophila melanogaster ZBMEL84 CBA35202.1 E1UIB9  
 moj9 (fragment)   Drosophila mojavensis 15081-1351.03 AAZ42646.1 Q2VKK9  
 moj9 (fragment)   Drosophila mojavensis 15081-1351.09 AAZ42647.1 Q2VKK6  
 moj9 (fragment)   Drosophila mojavensis 15081-1351.12 AAZ42648.1 Q2VKK7  
 moj9 (fragment)   Drosophila mojavensis 15081-1351.14 AAZ42649.1 Q2VKK6  
 moj9 (fragment)   Drosophila mojavensis 15081-1352.00 AAZ42650.1 Q2VKK6  
 moj9 (fragment)   Drosophila mojavensis 15081-1352.01 AAZ42651.1 Q2VKK6  
 moj9 (fragment)   Drosophila mojavensis 15081-1352.02 AAZ42652.1 Q2VKK6  
 moj9 (fragment)   Drosophila mulleri 15081-1371.00 AAZ42653.1 Q2VKK2  
 imaginal disc growth factor 3 (Idgf3)   Drosophila simulans 5F AAM69665.1 Q8MX32  
 imaginal disc growth factor 1 (Idgf1)   Drosophila simulans 5F AAM69643.1 Q8MX41  
 imaginal disc growth factor 3 (Idgf3)   Drosophila yakuba #14021-0261.0 AAM69666.1 Q8MX31  
 imaginal disc growth factor 1 (Idgf1)   Drosophila yakuba #14021-0261.0 AAM69644.1 Q8MX40  
 chitinase   Eisenia andrei ALG76037.1    
 chitinase (Ef-chI)   Eisenia fetida BAS18737.1    
 Chit3-1   Elaeis guineensis AFV30205.1    
 Chit5-1   Elaeis guineensis AFV30206.1    
 EMIHUDRAFT_415154 (fragment)   Emiliania huxleyi CCMP1516 EOD34344.1    
 EMIHUDRAFT_225160 (fragment)   Emiliania huxleyi CCMP1516 EOD37614.1    
 chitinase, partial (fragment)   Endromis versicolora ANT95802.1    
 chitinase 3.2.1.14 Entamoeba dispar SAW 1734 AAB52722.1 P92134  
 EDI_120190   Entamoeba dispar SAW760 EDR28415.1 B0EAL9  
 chitinase (EhCHT1;EHI_109890) 3.2.1.14 Entamoeba histolytica HM-1:IMSS AAB52723.1
EAL46819.1
P90546  
 chitinase 1 (Chi1;Chit1;EiChit1) 3.2.1.14 Entamoeba invadens IP-1 AAB52724.1 P90547  
 chitinase 4 (Chit4;EiChit4)   Entamoeba invadens IP-1 BAK18782.1    
 chitinase 2 (Chi2;Chit2;EiChit2) 3.2.1.14 Entamoeba invadens IP-1 ABC59330.2
ABC59330.1
Q2LEA8  
 chitinase 3 (Chi3;Chit3;EiChit3) 3.2.1.14 Entamoeba invadens IP-1 ABC59331.1 Q2LEA7  
 Cht1 (fragment)   Entomophthora planchoniana ADK37845.1 E2EYZ0  
 Cht2 (fragment)   Entomophthora planchoniana ADK37847.1 E2EYZ2  
 chitinase, partial (fragment)   Epermenia illigerella ANT95806.1    
 gastric chitinase (fragment)   Epinephelus bruneus AEB31342.1    
 chitinase 1   Epinephelus coioides ACN38311.1 D2CZD2  
 chitinase 2   Epinephelus coioides ACN38310.1 D2CZD1  
 chitinase (fragment)   Epinephelus coioides ADG29187.1 D6PVU2  
 chitinase A (EaChiA) 3.2.1.14 Equisetum arvense BAI22848.1 C7G3I3  
 chitotriosidase (Chit1) 3.2.1.14 Equus caballus ABV53445.1
ABX82529.1
B7S833  
 Ecym_3107   Eremothecium cymbalariae DBVPG#7215 AET38615.1    
 Ecym_4512   Eremothecium cymbalariae DBVPG#7215 AET39549.1    
 ACL166W   Eremothecium gossypii ATCC 10895 AAS51062.1 Q75CT5  
 FAGOS_FACL166W   Eremothecium gossypii FDAG1 AEY95352.1    
 AW171_hschr74041   Eremothecium sinecaudum ATCC 58844 AMD22033.1    
 chitinase 1 (fragment)   Eriocheir sinensis AKP18000.1    
 chitinase 4   Eriocheir sinensis AKP18003.1    
 chitinase 6 (fragment)   Eriocheir sinensis AKP18004.1    
 chitinase 2   Eriocheir sinensis AKP18001.1    
 chitinase 3   Eriocheir sinensis AKP18002.1    
 chitinase   Eriocheir sinensis AHZ21076.1    
 ORF (fragment)   Esteya vermicola CBS 115803 AGU16972.1    
 chitinase, partial (fragment)   Ethmia pusiella ANT95796.1    
 chitinase III (ELC) (fragment) 3.2.1.14 Euphorbia characias AGX26690.2
AGX26690.1
   
 chitotriosidase   Euprymna scolopes AHM92582.1    
 EsChit1   Euprymna scolopes AIZ97492.1    
 oviductal glycoprotein (Muc9)   Felis catus ADU04380.1    
 chitinase 3 (Chi3;FcChi-3) 3.2.1.14 Fenneropenaeus chinensis AAY44300.1 Q1L837  
 chitinase 1 (Chi1;FcChi-1)   Fenneropenaeus chinensis ABB85237.1 A0S0E3  
 acidic chitinase 3.2.1.14 Ficus pumila var. awkeotsang AAQ07267.1 Q71HN4  
 endo-β-N-acetylglucosaminidase (Endo FV;EndO) 3.2.1.96 Flammulina velutipes ACV60538.1 D1GA49  
 ORF   Flammulina velutipes KACC 42777 ADX07298.1    
 chitinase 3 (Chi3) 3.2.1.14 Fragaria x ananassa AAD22114.1 Q9XF93  
 FFUJ_08250   Fusarium fujikuroi IMI 58289 CCT71657.1    
 FFUJ_10978   Fusarium fujikuroi IMI 58289 CCT74905.1    
 FFUJ_01301   Fusarium fujikuroi IMI 58289 CCT62173.1    
 FFUJ_00649   Fusarium fujikuroi IMI 58289 CCT62766.1    
 FFUJ_02318   Fusarium fujikuroi IMI 58289 CCT65379.1    
 FFUJ_02425   Fusarium fujikuroi IMI 58289 CCT65482.1    
 FFUJ_13162   Fusarium fujikuroi IMI 58289 CCT66985.1    
 FFUJ_14326   Fusarium fujikuroi IMI 58289 CCT69181.1    
 FFUJ_05909   Fusarium fujikuroi IMI 58289 CCT69979.1    
 FFUJ_08481   Fusarium fujikuroi IMI 58289 CCT71444.1    
 FFUJ_12892   Fusarium fujikuroi IMI 58289 CCT72994.1    
 FFUJ_09588   Fusarium fujikuroi IMI 58289 CCT73606.1    
 FFUJ_10531   Fusarium fujikuroi IMI 58289 CCT74476.1    
 FFUJ_02254   Fusarium fujikuroi IMI 58289 CCT65320.1    
 FFUJ_14547 (fragment)   Fusarium fujikuroi IMI 58289 CCT67606.1    
 FFUJ_12107   Fusarium fujikuroi IMI 58289 CCT76082.1    
 FFUJ_05118   Fusarium fujikuroi IMI 58289 CCT65062.1    
 FGRAMPH1_01T02775   Fusarium graminearum PH-1 SCB64187.1    
 unnamed protein product   Fusarium graminearum PH-1 CEF87375.1    
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