Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (14935); Uniprot accession (3282); PDB accession (301); 3D entries (77); cryst (4)
All (13391) Archaea (61) Bacteria (9754) Eukaryota (3083) Viruses (256) unclassified (237) Structure (77 - 4 cryst) Characterized (477)
| 1 | ... | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | ... | 31 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Cts1 (fragment)   Coccidioides posadasii IFM 4945 BAE20290.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 50993 BAE20301.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 50994 BAE20302.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 51112 BAE20304.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 54194 BAE20305.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 54195 BAE20306.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 54196 BAE20307.1 P0CB51
P54196
 
 complement fixation-chitinase 3.2.1.14 Coccidioides posadasii SILVEIRA AAB48567.1
AAB48566.1
P0CB51
P54196
1D2K[A]
1LL4[A]
1LL6[A]
1LL7[A]
 AR-52 (fragment)   Coffea arabica AAD26856.1 Q9XF03  
 class III chitinase / allergen (Cof a 1) (fragment)   Coffea arabica ADH10372.1 D7REL9  
 Clxip (fragment)   Coffea arabica ADZ48381.1    
 class III chitinase (Chi2)   Coffea arabica CAJ43737.1 A0PD76  
 chitinase (CH1) 3.2.1.14 Coniothyrium minitans CM-2 AAG00504.1 Q9HGU5  
 chitinase 1   Conogethes punctiferalis CQ ASM94206.1    
 chitinase 7   Conogethes punctiferalis CQ ASM94207.1    
 chitinase 7   Conogethes punctiferalis CQ ASM94207.1    
 chitinase 1 (Chi1) 3.2.1.14 Coprinellus congregatus A1 = CC16 CAQ51152.1 B2G3S2  
 chitinase 2 (Chi2) 3.2.1.14 Coprinellus congregatus H99 AFD19009.1    
 chitinase (ChiIII;CC1G_04407) 3.2.1.14 Coprinopsis cinerea okayama7#130 EAU93428.2    
 ORF (fragment)   Coptotermes formosanus AGM32304.1    
 ORF (fragment)   Coptotermes formosanus AGM32594.1    
 chitinase 2   Coptotermes formosanus AHB39935.1    
 chitinase   Cordyceps confragosa 43H AFW90080.1    
 chitinase (VlCHI) 3.2.1.14 Cordyceps confragosa CA-12 AGU42402.1
AGU42403.1
   
 endochitinase (Chit2)   Cordyceps confragosa V3450 AFR13053.1    
 endochitinase (Chit3)   Cordyceps confragosa Vl6063 AFR13054.1    
 endochitinase (Chit1)   Cordyceps confragosa Vp28 AFR13052.1    
 chitinase 2 (fragment)   Cosmopolites sordidus ANW69904.1    
 chitinase 1 (fragment)   Cosmopolites sordidus ANW69903.1    
 chitinase, partial (fragment)   Cossus cossus ANT95798.1    
 Clp2   Crassostrea gigas CAI96023.1 Q1RQ22  
 Clp3   Crassostrea gigas CAI96024.1 Q1RQ21  
 Chit2 (fragment) 3.2.1.14 Crassostrea gigas CAI96025.1 Q1RQ20  
 chitinase (Chit;Chit1;Cg-Chit;Cg-Chit1)   Crassostrea gigas CAI96026.1 Q1RQ19  
 Chit3 (fragment) 3.2.1.14 Crassostrea gigas CAI96027.1 Q1RQ18  
 Clp1   Crassostrea gigas CAI96028.1
CAI96029.1
Q1RQ17  
 chitinase (CVC) (partial)   Crocus vernus     3SIM[B]
3SIM[A]
 acidic endochitinase (ChiA)   Crucihimalaya himalaica JOS18 BAC11880.1 Q8LP08  
 acidic endochitinase (ChiA)   Crucihimalaya wallichii JS5 BAC11883.1 Q8LP05  
 CGB_E2500C   Cryptococcus gattii WM276 ADV22450.1    
 CGB_G4360C   Cryptococcus gattii WM276 ADV23552.1    
 CGB_H4180C   Cryptococcus gattii WM276 ADV24093.1    
 CGB_K3410C   Cryptococcus gattii WM276 ADV25006.1    
 CNAG_02598   Cryptococcus neoformans var. grubii H99 AFR94094.1
AFR94094.2
   
 CNAG_02351   Cryptococcus neoformans var. grubii H99 AFR95478.1    
 CNAG_03412   Cryptococcus neoformans var. grubii H99 AFR96636.1    
 CNAG_04245   Cryptococcus neoformans var. grubii H99 AFR96977.1
AFR96977.2
AGV14596.1
   
 CNG01720   Cryptococcus neoformans var. neoformans JEC21 AAW44589.1
AAW44589.2
Q5KE51  
 CNI03860   Cryptococcus neoformans var. neoformans JEC21 AAW45591.1 Q5KB41  
 CNE01990   Cryptococcus neoformans var. neoformans JEC21 AAW43533.1 Q5KGX6  
 CNK00840   Cryptococcus neoformans var. neoformans JEC21 AAW46130.1
AAW46130.2
Q5K9T4  
 chitinase 2   Cucumis melo AMP41495.1
ANB86007.1
   
 chitinase 1 (fragment)   Cucumis melo AMP41494.1
ANB86002.1
ANB86006.1
   
 chitinase (ChT)   Cucumis melo ANB86005.1    
 chitinase 2 (Cht2)   Cucumis melo ANB86003.1    
 chitinase 1 3.2.1.14 Cucumis melo AAF64474.1 Q9M544  
 family 18 chitinase (fragment)   Cucumis melo var. saccharinus APF47213.1    
 chitinase 3.2.1.14 Cucumis sativus AAA33120.1
AAC37395.1
ABK55716.2
ADG56718.1
ALT53700.1
P17541  
 ORF1   Cucumis sativus AAC37394.1 Q39656  
 ORF3   Cucumis sativus AAC37396.1 Q39657  
 acidic class III chitinase   Cucurbita maxima AIM62181.1    
 chitinase (PLC) 3.2.1.14 Cucurbita moschata AAD53006.1 Q9SQI0  
 Chi1 (fragment)   Cutaneotrichosporon cutaneum DSM 70675 AAX59703.1 Q2TIM2  
 CYFA0S_11e00892g   Cyberlindnera fabianii YJS4271 CDR43160.1    
 CYFA0S_11e01992g   Cyberlindnera fabianii YJS4271 CDR43229.1    
 CYFA0S_29e01068g   Cyberlindnera fabianii YJS4271 CDR47159.1    
 chitinase A (ChiA;CrChiA;CrChi-A) 3.2.1.14 Cycas revoluta BAD98525.1 Q4W6L6 3WIJ[A]
4MNJ[A]
4MNK[A]
4MNL[A]
4MNM[A]
4R5E[A]
 chitinase, partial (fragment)   Cyclophora punctaria ANT95794.1    
 pathogenesis related protein 3, partial (Pr3-ch3) (fragment)   Cydonia oblonga AFM77007.1    
 pathogenesis related protein 3, partial (Pr3-ch3) (fragment)   Cydonia oblonga AFM77006.1    
 Pr8   Cydonia oblonga AFQ23971.1    
 Pr8   Cydonia oblonga AFQ23973.1    
 pathogenesis-related protein 3 (Pr3)   Cydonia oblonga AFV46125.1    
 pathogenesis-related protein 3 (Pr3)   Cydonia oblonga AFV46126.1    
 class III endochitinase   Dactylis glomerata AET86622.2    
 Zgc:65788 (CHIA.6)   Danio rerio AAH56337.1
AAH46004.1
AAH65583.1
NP_955897.1
Q6PHU7
Q7ZV48
 
 Zgc:55406 (CHIA.3)   Danio rerio AAH65893.1
AAH45331.1
Q6NZZ8  
 Zgc:56053 (CHIA.1)   Danio rerio AAH45887.1
AAI65730.1
Q7ZVF1  
 Zgc:55941 (CHIA.2)   Danio rerio AAH44549.1
AAH65885.1
Q803B7  
 Zgc:63792 (ChiA;CHIA.4)   Danio rerio AAH54942.1
AAQ97758.1
NP_956740.1
Q7SYA8  
 Zgc:109937 (CTBS)   Danio rerio AAH72723.2
AAH72723.1
AAH95064.1
AAI64759.1
Q6GQL9  
 Zgc:173927 (CHIA.5)   Danio rerio AAI53463.1
AAI71633.1
A8E550  
 chitinase 15, partial (fragment)   Daphnia arenata AFI40013.1    
 chitinase 16, partial (fragment)   Daphnia arenata AFI40033.1    
 chitinase 1, partial (fragment)   Daphnia arenata AFI40035.1    
 chitinase 9, partial (fragment)   Daphnia arenata AFI40049.1    
 chitinase 17, partial (fragment)   Daphnia arenata AFI40060.1    
 chitinase 15, partial (fragment)   Daphnia parvula AFI40004.1    
 chitinase 15, partial (fragment)   Daphnia parvula AFI40014.1    
 chitinase 15, partial (fragment)   Daphnia parvula AFI40018.1    
 chitinase 16, partial (fragment)   Daphnia parvula AFI40027.1
AFI40028.1
   
 chitinase 16, partial (fragment)   Daphnia parvula AFI40029.1    
 chitinase 16, partial (fragment)   Daphnia parvula AFI40030.1    
 chitinase 17, partial (fragment)   Daphnia parvula AFI40053.1
AFI40054.1
   
 chitinase 17, partial (fragment)   Daphnia parvula AFI40062.1    
 chitinase 15, partial (fragment)   Daphnia pulex AFI40005.1    
 chitinase 15, partial (fragment)   Daphnia pulex AFI40006.1    
 chitinase 15, partial (fragment)   Daphnia pulex AFI40007.1    
 chitinase 15, partial (fragment)   Daphnia pulex AFI40008.1    
 chitinase 15, partial (fragment)   Daphnia pulex AFI40009.1    
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