Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (14617); Uniprot accession (3282); PDB accession (301); 3D entries (77); cryst (4)
All (13074) Archaea (61) Bacteria (9464) Eukaryota (3057) Viruses (255) unclassified (237) Structure (77 - 4 cryst) Characterized (477)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 31 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CD36_35130 (Cht3)   Candida dubliniensis CD36 CAX40479.1 B9WN12  
 CAGL0M09779g   Candida glabrata CBS 138 CAG62749.1 Q6FJ23  
 CAGL0A02904g   Candida glabrata CBS 138 CAG57785.1 Q6FY50  
 SAMEA4029010_CIC11G00000001381   [Candida] intermedia CBS 141442 SGZ47291.1    
 SAMEA4029010_CIC11G00000004537   [Candida] intermedia CBS 141442 SGZ49005.1    
 SAMEA4029010_CIC11G00000002085   [Candida] intermedia CBS 141442 SGZ49473.1    
 SAMEA4029009_CIC11G00000005869   [Candida] intermedia PYCC 4715 SGZ49527.1    
 SAMEA4029009_CIC11G00000004933   [Candida] intermedia PYCC 4715 SGZ58721.1    
 SAMEA4029009_CIC11G00000000395 (fragment)   [Candida] intermedia PYCC 4715 SGZ53157.1    
 Cht2 chitinase, partial (fragment)   Candida metapsilosis HS7 BAS29670.1    
 CORT_0A00160   Candida orthopsilosis Co 90-125 CCG20410.1    
 CORT_0A11290   Candida orthopsilosis Co 90-125 CCG21514.1    
 CORT_0B02290   Candida orthopsilosis Co 90-125 CCG21946.1    
 CORT_0B02300   Candida orthopsilosis Co 90-125 CCG21947.1    
 CORT_0D00740   Candida orthopsilosis Co 90-125 CCG22922.1    
 CPAR2_200660   Candida parapsilosis CDC317 CCE42423.1    
 CPAR2_211950   Candida parapsilosis CDC317 CCE43551.1    
 CPAR2_502120   Candida parapsilosis CDC317 CCE43987.1    
 CPAR2_502130   Candida parapsilosis CDC317 CCE43988.1    
 CPAR2_502140   Candida parapsilosis CDC317 CCE43989.1    
 CPAR2_800050   Candida parapsilosis CDC317 CCE41453.1    
 Chi3L1   Canis lupus familiaris ADD17685.1 D3YJ60  
 Di-N-acetylchitobiase (LOC490188)   Canis lupus familiaris XP_547309.2 E2RLQ5  
 signalling protein (SPG-40;MGP-40;BP40;CHI3L1)   Capra hircus AAL87007.1 Q8SPQ0 1LJY[A]
1QZO[A]
1SYT[A]
1ZBV[A]
1ZBW[A]
1ZU6[A]
1ZU7[A]
1ZU8[A]
1ZU9[A]
2A09[A]
2A0O[A]
2AOS[A]
2B2Z[A]
2B31[A]
2B40[A]
2B41[A]
2DSZ[A]
2DT0[A]
2DT1[A]
2DT2[A]
2DT3[A]
2O92[A]
2OLH[A]
 oviductin (Ovn)   Capra hircus ABF20534.1 A4Z8Y2  
 chitinase (Chi3-P1) 3.2.1.14 Capsicum annuum AAN37389.1
AAN37390.1
AAN37391.1
AAN37392.1
AAN37393.1
Q8GRR2
Q8H6X6
Q8H6X7
 
 class III chitinase (CHI3;CgCHI3)   Casuarina glauca ABL74451.1 A1YTJ5  
 ORF (fragment)   Cenchrus americanus AKB08896.1    
 chitinase (Chi58) 3.2.1.14 Chaetomium cupreum ABK27625.2
ABI48362.2
Q0GA12  
 endochitinase (Chi46)   Chaetomium cupreum ABV55545.1 A8D8E9  
 endochitinase (Chi46) 3.2.1.14 Chaetomium globosum ABI95486.1
ABI95487.1
Q06HA3  
 chitinase (Chit1;CtChit1) 3.2.1.14 Chaetomium thermophilum CT2 ACD86396.1 B3GGC7  
 chitinase   Charybdis japonica AFF59213.1    
 venom protein (Ci-45)   Chelonus inanitus CBM69270.1    
 venom protein (Ci-48b)   Chelonus inanitus CBM69272.1    
 chitinase 3.2.1.14 Chelonus sp. near curvimaculatus AAA61639.1 Q23737  
 chitinase 2, partial (fragment)   Cherax quadricarinatus ALC79576.1    
 chitinase (fragment)   Cherax quadricarinatus AIN40243.1    
 chitinase 3, partial (fragment)   Chilo suppressalis ALO79340.1    
 chitinase 1 (fragment)   Chilo suppressalis ALO79338.1    
 chitinase 4 (fragment)   Chilo suppressalis ALO79341.1    
 chitinase 10 (fragment)   Chilo suppressalis ALO79347.1    
 chitinase 9, partial (fragment)   Chilo suppressalis ALO79346.1    
 chitinase 7, partial (fragment)   Chilo suppressalis ALO79344.1    
 chitinase 2   Chilo suppressalis ALO79339.1    
 chitinase 12 (fragment)   Chilo suppressalis ALO79349.1    
 chitinase 11   Chilo suppressalis ALO79348.1    
 chitinase 6 (fragment)   Chilo suppressalis ALO79343.1    
 chitinase 8 (fragment)   Chilo suppressalis ALO79345.1    
 chitinase   Chilo suppressalis AAW30162.1
ALO79342.1
Q2TPT7  
 imaginal discs growth factor   Chilo suppressalis AGU16453.1    
 chitinase 3.2.1.14 Chironomus tentans CAA73685.1 O01935  
 chitinase 3.2.1.14 Chironomus tentans CAA73686.1 O01936  
 chitinase (hChti-1) (fragment)   Chlorella sp. NC64A BAF40429.1 A0ZSK1  
 chitinase, partial (fragment)   Choreutis pariana ANT95809.1    
 chitinase (Chit) 3.2.1.14 Choristoneura fumiferana AAM43792.1 Q8MTK0  
 chitinase 1 (Chit-1)   Chrysomela tremulae ACP18829.1 C3UTC0  
 chitinase 2 (Chit-2) (fragment)   Chrysomela tremulae ACP18840.1 C3UTD1  
 chitinase class III (CpCC-III) 3.2.1.14 Cicer arietinum CAA49998.1 P36908  
 chitinase   Cicer arietinum AII99856.1    
 chitinase   Cicer arietinum AII99857.1    
 chitinase   Cicer arietinum AII99858.1    
 chitinase (fragment)   Cicer arietinum AII99854.1    
 chitinase (fragment)   Cicer arietinum AII99855.1    
 chitinase (Ci-GH18)   Ciona intestinalis BAF74591.1 A7BK23  
 acidic class III chitinase   Citrullus colocynthis AFK31317.1    
 ORF   Citrullus lanatus ABA26457.1 Q09Y38  
 Ech37 (CrEch37)   Clonostachys rosea ABD48217.1 A2SW11  
 Ech58 (CrEch58)   Clonostachys rosea ABD48218.1 A2SW12  
 Ech42 (CrEch42) (fragment)   Clonostachys rosea ABG02418.1 A2T243  
 endochitinase (Chi67)   Clonostachys rosea 67-1 ANA50873.1    
 chitinase (CrChi1) 3.2.1.14 Clonostachys rosea CGMCC 0806 ABV57861.1 A9LI60 3G6L[A]
3G6M[A]
 CHIB2 (fragment)   Clonostachys rosea IK276 AIZ66850.1    
 chitinase 3, partial (fragment)   Cnaphalocrocis medinalis AJG44543.1    
 chitinase 3, partial (fragment)   Cnaphalocrocis medinalis AJG44543.1    
 chitinase 3, partial (fragment)   Cnaphalocrocis medinalis AJG44543.1    
 chitinase 5   Cnaphalocrocis medinalis AJG44545.1    
 chitinase 2   Cnaphalocrocis medinalis AJG44542.1    
 chitinase   Cnaphalocrocis medinalis AII78788.1    
 Cts2 (fragment)   Coccidioides immitis CAC29128.1
CAC29131.1
CAC29132.1
CAC29133.1
Q1E3R8  
 Cts1 (fragment)   Coccidioides immitis IFM 45815 BAE20296.1 Q1E3R8  
 Cts1 (fragment)   Coccidioides immitis IFM 45816 BAE20297.1 Q1E3R8  
 Cts1 (fragment)   Coccidioides immitis IFM 46868 BAE20299.1 Q1E3R8  
 Cts1 (fragment)   Coccidioides immitis IFM 50992 BAE20300.1 Q1E3R8  
 Cts1 (fragment)   Coccidioides immitis IFM 50995 BAE20303.1 Q1E3R8  
 chitinase 1 (Cts1) 3.2.1.14 Coccidioides posadasii AAA92643.1
AAA96515.1
AAB06687.1
CAC29129.1
CAC29130.1
P54196
P54196
 
 chitinase 2 (Cts2) 3.2.1.14 Coccidioides posadasii AAA92642.1
ACC06929.1
P54197  
 chitinase 8 (Cts8)   Coccidioides posadasii ACT90641.1 C7B798  
 chitinase 3 (Cts3)   Coccidioides posadasii AAO88269.1 Q874H8  
 chitinase 4 (Cts4)   Coccidioides posadasii AAP46398.1 Q7ZA41  
 chitinase 6 (Cts6) (fragment)   Coccidioides posadasii AAP80452.1 Q7Z962  
 chitinase 5 (Cts5)   Coccidioides posadasii AAR18253.1 Q5VHW7  
 chitinase 7 (Cts7)   Coccidioides posadasii AAR18252.1 Q5VHW8  
 Cts1 (fragment)   Coccidioides posadasii IFM 45809 BAE20291.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 45810 BAE20292.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 45811 BAE20293.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 45812 BAE20294.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 45813 BAE20295.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 45817 BAE20298.1 P0CB51
P54196
 
 Cts1 (fragment)   Coccidioides posadasii IFM 4935 BAE20289.1 P0CB51
P54196
 
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