Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (16535); Uniprot accession (3282); PDB accession (322); 3D entries (84); cryst (3)
All (14978) Archaea (62) Bacteria (11108) Eukaryota (3259) Viruses (312) unclassified (237) Structure (84 - 3 cryst) Characterized (481)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ... | 33 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0081 AFL38019.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0082 AFL38020.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0083 AFL38021.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0084 AFL38022.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0085 AFL38023.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0086 AFL38024.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0087 AFL38025.1    
 CHT-1, partial (fragment)   Caenorhabditis sp. 23 AD-2012 VX0088 AFL38026.1    
 acidic mammalian chitinase (MchiA)   Callithrix jacchus AUE24253.1    
 acidic mammalian chitinase (HchiA)   Callithrix jacchus AUE24252.1    
 CHI3L1-like protein (fragment)   Callithrix jacchus ABQ22343.1 A6MJV2  
 di-N-acetylchitobiase   Callorhinchus milii AFM90998.1    
 Ctbs protein   Callorhinchus milii AFK11362.1    
 ORF (fragment)   Callorhinchus milii AFP12700.1    
 ORF   Callorhinchus milii AFO95717.1    
 concanavalin B   Canavalia ensiformis CAA58450.1 P49347 1CNV[A]
6CAF[A]
 narbonin   Canavalia ensiformis CAA86823.1 Q39486  
 class III chitinase   Canavalia gladiata ANH09332.1    
 chitinase 1 (Cht1) 3.2.1.14 Candida albicans AAC49409.2 P46876  
 chitinase 2 (Cht2) 3.2.1.14 Candida albicans AAA68015.1
AAS66201.1
P40953  
 chitinase 3 (Cht3; CAALFM_CR10110WA) 3.2.1.14 Candida albicans SC5314 AOW31663.1
AAA68016.1
AAV05306.1
EAL00460.1
P40954  
 CAALFM_C202010CA (Cht4)   Candida albicans SC5314 AOW27242.1    
 CAALFM_CR00180CA (Cht1)   Candida albicans SC5314 AOW30789.1    
 CAALFM_C504130CA (Cht2)   Candida albicans SC5314 AOW29822.1    
 CD36_16810 (Cht4)   Candida dubliniensis CD36 CAX43460.1 B9WAP0  
 CD36_53830 (Cht2)   Candida dubliniensis CD36 CAX41761.1 B9WHW6  
 CD36_25200 (Cht1)   Candida dubliniensis CD36 CAX39561.1 B9WKL3  
 CD36_35130 (Cht3)   Candida dubliniensis CD36 CAX40479.1 B9WN12  
 CAGL0M09779g   [Candida] glabrata CBS 138 CAG62749.1 Q6FJ23  
 CAGL0A02904g   [Candida] glabrata CBS 138 CAG57785.1 Q6FY50  
 SAMEA4029010_CIC11G00000001381   [Candida] intermedia CBS 141442 SGZ47291.1    
 SAMEA4029010_CIC11G00000004537   [Candida] intermedia CBS 141442 SGZ49005.1    
 SAMEA4029010_CIC11G00000002085   [Candida] intermedia CBS 141442 SGZ49473.1    
 SAMEA4029009_CIC11G00000005869   [Candida] intermedia PYCC 4715 SGZ49527.1    
 SAMEA4029009_CIC11G00000004933   [Candida] intermedia PYCC 4715 SGZ58721.1    
 SAMEA4029009_CIC11G00000000395 (fragment)   [Candida] intermedia PYCC 4715 SGZ53157.1    
 Cht2 chitinase, partial (fragment)   Candida metapsilosis HS7 BAS29670.1    
 CORT_0A00160   Candida orthopsilosis Co 90-125 CCG20410.1    
 CORT_0A11290   Candida orthopsilosis Co 90-125 CCG21514.1    
 CORT_0B02290   Candida orthopsilosis Co 90-125 CCG21946.1    
 CORT_0B02300   Candida orthopsilosis Co 90-125 CCG21947.1    
 CORT_0D00740   Candida orthopsilosis Co 90-125 CCG22922.1    
 CPAR2_200660   Candida parapsilosis CDC317 CCE42423.1    
 CPAR2_211950   Candida parapsilosis CDC317 CCE43551.1    
 CPAR2_502120   Candida parapsilosis CDC317 CCE43987.1    
 CPAR2_502130   Candida parapsilosis CDC317 CCE43988.1    
 CPAR2_502140   Candida parapsilosis CDC317 CCE43989.1    
 CPAR2_800050   Candida parapsilosis CDC317 CCE41453.1    
 Chi3L1   Canis lupus familiaris ADD17685.1 D3YJ60  
 Di-N-acetylchitobiase (LOC490188)   Canis lupus familiaris XP_547309.2 E2RLQ5  
 signalling protein (SPG-40;MGP-40;BP40;CHI3L1)   Capra hircus AAL87007.1 Q8SPQ0 1LJY[A]
1QZO[A]
1SYT[A]
1ZBV[A]
1ZBW[A]
1ZU6[A]
1ZU7[A]
1ZU8[A]
1ZU9[A]
2A09[A]
2A0O[A]
2AOS[A]
2B2Z[A]
2B31[A]
2B40[A]
2B41[A]
2DSZ[A]
2DT0[A]
2DT1[A]
2DT2[A]
2DT3[A]
2O92[A]
2OLH[A]
 oviductin (Ovn)   Capra hircus ABF20534.1 A4Z8Y2  
 chitinase (Chi3-P1) 3.2.1.14 Capsicum annuum AAN37389.1
AAN37390.1
AAN37391.1
AAN37392.1
AAN37393.1
Q8GRR2
Q8H6X6
Q8H6X7
 
 class III chitinase (CHI3;CgCHI3)   Casuarina glauca ABL74451.1 A1YTJ5  
 ORF (fragment)   Cenchrus americanus AKB08896.1    
 acidic mammalian chitinase (MchiA)   Cercopithecus mitis AUE24254.1    
 chitinase (Chi58) 3.2.1.14 Chaetomium cupreum ABK27625.2
ABI48362.2
Q0GA12  
 endochitinase (Chi46)   Chaetomium cupreum ABV55545.1 A8D8E9  
 endochitinase (Chi46) 3.2.1.14 Chaetomium globosum ABI95486.1
ABI95487.1
Q06HA3  
 chitinase (Chit1;CtChit1) 3.2.1.14 Chaetomium thermophilum CT2 ACD86396.1 B3GGC7  
 chitinase   Charybdis japonica AFF59213.1    
 venom protein (Ci-45)   Chelonus inanitus CBM69270.1    
 venom protein (Ci-48b)   Chelonus inanitus CBM69272.1    
 chitinase 3.2.1.14 Chelonus sp. near curvimaculatus AAA61639.1 Q23737  
 chitinase 2, partial (fragment)   Cherax quadricarinatus ALC79576.1    
 chitinase (fragment)   Cherax quadricarinatus AIN40243.1    
 chitinase 3, partial (fragment)   Chilo suppressalis ALO79340.1    
 chitinase 1 (fragment)   Chilo suppressalis ALO79338.1    
 chitinase 4 (fragment)   Chilo suppressalis ALO79341.1    
 chitinase 10 (fragment)   Chilo suppressalis ALO79347.1    
 chitinase 9, partial (fragment)   Chilo suppressalis ALO79346.1    
 chitinase 7, partial (fragment)   Chilo suppressalis ALO79344.1    
 chitinase 2   Chilo suppressalis ALO79339.1    
 chitinase 12 (fragment)   Chilo suppressalis ALO79349.1    
 chitinase 11   Chilo suppressalis ALO79348.1    
 chitinase 6 (fragment)   Chilo suppressalis ALO79343.1    
 chitinase 8 (fragment)   Chilo suppressalis ALO79345.1    
 chitinase   Chilo suppressalis AAW30162.1
ALO79342.1
Q2TPT7  
 imaginal discs growth factor   Chilo suppressalis AGU16453.1    
 chitinase 3.2.1.14 Chironomus tentans CAA73685.1 O01935  
 chitinase 3.2.1.14 Chironomus tentans CAA73686.1 O01936  
 chitinase (hChti-1) (fragment)   Chlorella sp. NC64A BAF40429.1 A0ZSK1  
 acidic mammalian chitinase (MchiA)   Chlorocebus aethiops AUE24250.1    
 chitinase, partial (fragment)   Choreutis pariana ANT95809.1    
 chitinase (Chit) 3.2.1.14 Choristoneura fumiferana AAM43792.1 Q8MTK0  
 chitinase 1 (Chit-1)   Chrysomela tremulae ACP18829.1 C3UTC0  
 chitinase 2 (Chit-2) (fragment)   Chrysomela tremulae ACP18840.1 C3UTD1  
 ORF (fragment)   Chrysomya megacephala ARA90552.1    
 ORF (fragment)   Chrysomya megacephala ARA90552.1    
 ORF (fragment)   Chrysomya megacephala ARA90549.1    
 Endochitinase, partial   Chrysomya megacephala ARA90543.1    
 ORF (fragment)   Chrysomya megacephala ARA90531.1    
 ORF (fragment)   Chrysomya megacephala ARA90539.1    
 ORF   Chrysomya megacephala ARA90546.1    
 ORF (fragment)   Chrysomya megacephala ARA90556.1    
 ORF (fragment)   Chrysomya megacephala ARA90558.1    
 ORF (fragment)   Chrysomya megacephala ARA90542.1    
 ORF (fragment)   Chrysomya megacephala ARA90553.1    
 ORF (fragment)   Chrysomya megacephala ARA90553.1    
 ORF (fragment)   Chrysomya megacephala ARA90533.1    
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