Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (14617); Uniprot accession (3282); PDB accession (301); 3D entries (77); cryst (4)
All (13074) Archaea (61) Bacteria (9464) Eukaryota (3057) Viruses (255) unclassified (237) Structure (77 - 4 cryst) Characterized (477)
| 1 | 2 | 3 | 4 | 5 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 chitinase (Chi1;TfChi1) 3.2.1.14 Talaromyces flavus ADV02754.1
ADV02753.1
   
 chitinase (Chi) 3.2.1.14 Tenebrio molitor AAP92418.1 Q7YZB9  
 chitinase 3.2.1.14 Thermoascus aurantiacus var. aurantiacus ADT82646.1
ADT82647.1
   
 endochitinase (Chit1;TaChit1) 3.2.1.14 Thermoascus aurantiacus var. levisporus ABS00927.1
ABI95802.1
A6YJX1  
 chitinase 2 (Chit2) 3.2.1.14 Thermomyces lanuginosus SSBP AIW06012.1    
 chitinase (ChiT;Chi48) 3.2.1.14 Thermomyces lanuginosus SY2 / RMB AAY99632.1
AAV58834.1
Q4FCX2  
 chitinase 5 / 1 (Cht5;Chi-1) 3.2.1.14 Tribolium castaneum AAV74190.1
NP_001034524.1
Q5QE61  
 chitinase 7 (Cht7) 3.2.1.14 Tribolium castaneum ABG47445.1
NP_001036035.1
Q0Z942  
 chitinase 7 (Cht7) 3.2.1.14 Tribolium castaneum ABG47445.1
NP_001036035.1
Q0Z942  
 chitinase 10 (Cht10) 3.2.1.14 Tribolium castaneum ABG47448.1
NP_001036067.1
Q0Z939  
 chitinase 10 (Cht10) 3.2.1.14 Tribolium castaneum ABG47448.1
NP_001036067.1
Q0Z939  
 chitinase 10 (Cht10) 3.2.1.14 Tribolium castaneum ABG47448.1
NP_001036067.1
Q0Z939  
 chitinase 10 (Cht10) 3.2.1.14 Tribolium castaneum ABG47448.1
NP_001036067.1
Q0Z939  
 chitinase 10 (Cht10) 3.2.1.14 Tribolium castaneum ABG47448.1
NP_001036067.1
Q0Z939  
 chitinase (Ech42;Chit42) 3.2.1.14 Trichoderma asperellum AAF19623.1
AAF19620.1
AAF19624.1
AAF19627.1
AAG44827.1
AAG44828.1
AAP21814.1
AAV98503.1
ADT82645.1
Q86ZR3
Q9HDE4
Q9UV34
Q9UV37
Q9UV38
Q9UV41
 
 endochitinase (Chi2;Tachi2) 3.2.1.14 Trichoderma asperellum TD3104 ADZ48671.1    
 Chi42 3.2.1.14 Trichoderma asperellum TN42 ADI46582.1 D7RZT5  
 endochitinase (Chi1;Tachi1) 3.2.1.14 Trichoderma asperellum Tr10 ADV74846.1
ADV74845.1
   
 42 kDa endochitinase 3.2.1.14 Trichoderma atroviride DAOM 165779 AAF19614.1
AAF19615.1
AAG44825.1
AAG44826.1
Q9HDF0
Q9UV46
Q9UV47
 
 endo-β-N-acetylglucosaminidase (Eng18B;TRIATDRAFT_302173) 3.2.1.96 Trichoderma atroviride IMI 206040 EHK41777.1    
 endo-β-N-acetylglucosamidase (Eng18A;TRIATDRAFT_217415) 3.2.1.96 Trichoderma atroviride IMI 206040 EHK47006.1    
 endochitinase (Chit36P1) 3.2.1.14 Trichoderma atroviride P1 AAM77132.1 Q7Z8C9  
 endochitinase (Chit42) 3.2.1.14 Trichoderma atroviride PTCC5220 AAY84618.1
AAY84619.1
   
 chitinase (Ech42) 3.2.1.14 Trichoderma aureoviride AAW31950.1 Q5I6E0  
 endochitinase (Chit-HAM) 3.2.1.14 Trichoderma hamatum BAB40592.1 Q9C1T6  
 chitinase (Chit42) 3.2.1.14 Trichoderma hamatum LU593 AAC60385.1
AAP15043.1
O43111
Q86ZV4
 
 chitinase 3.2.1.14 Trichoderma hamatum TAM-61 CAA96021.1 Q99006  
 chitinase 37 (Chit37) 3.2.1.14 Trichoderma harzianum CECT 2413 AAM93195.1 Q8NJQ5  
 chitinase (Chit42) 3.2.1.14 Trichoderma harzianum CECT 2413 AAB34355.1 P48827  
 chitinase (Chit33) 3.2.1.14 Trichoderma harzianum CECT 2413 CAA56315.1 Q12713  
 chitinase (Chit42;ech-42;ECH42) 3.2.1.14 Trichoderma harzianum P1 / IMI206040 AAA18167.1
CAA55928.1
EHK45530.1
Q12735  
 endochitinase (Chit36) 3.2.1.14 Trichoderma harzianum RIFAI TM AAK54377.1 Q96VR2  
 endochitinase (Chit-HAR3) 3.2.1.14 Trichoderma harzianum SK-55 BAB40591.1 Q12735  
 chitinase I (Chit1;Ech42) 3.2.1.14 Trichoderma harzianum T-25-1 AAA98644.1
AAG44821.1
AAG44822.1
AAG44823.1
AAG44824.1
Q12710
Q9HDP2
 
 endochitinase (Chit-HAR2) 3.2.1.14 Trichoderma harzianum TH-2 BAB40590.1
ACJ38679.1
ACM47359.1
AEF28830.1
AEF28831.1
AEF28836.1
AEF28837.1
AEF28839.1
AEF28841.1
AEF28842.1
AEF28843.1
AEF28844.1
AEF28845.1
AEF28846.1
Q9C1T7  
 endochitinase (Chit-HAR1) 3.2.1.14 Trichoderma harzianum TMI-60638 BAB40589.1 Q9C1T8  
 chitinase 3.2.1.14 Trichoderma koningii ATCC 64262 AAF19612.1 Q9UV49  
 endochitinase (Chit-P) 3.2.1.14 Trichoderma pseudokoningii TMI-60683 BAB40594.1 Q9C1T4  
 chitinase (Chi46) 3.2.1.14 Trichoderma reesei BAD44715.1 Q65YQ7  
 mannosyl-glycoprotein endo-β-N-acetylglucosaminidase T (EndoT;Endo T;ENGase;Eng18A) 3.2.1.96 Trichoderma reesei RUT-C30 CAZ16624.1
CAL49862.1
CAL49863.1
C4RA89 4AC1[X]
 endochitinase 3.2.1.14 Trichoderma sp. HZ012 ABU41786.1 A7UGE4  
 endochitinase (Chit-G1) 3.2.1.14 Trichoderma virens FM-2 BAB40587.1 Q9C1U0  
 endochitinase (Cht42;Ech1) 3.2.1.14 Trichoderma virens Gv29-8 AAL78813.1
AAC05829.1
CAJ34422.1
O59928
Q8TGW8
 
 endochitinase (Chit-G2) 3.2.1.14 Trichoderma virens TMI-61314 BAB40588.1 Q9C1T9  
 endochitinase (Ech1) 3.2.1.14 Trichoderma virens UKM-1 ABI30336.1
ABI30335.1
Q8TGW8  
 chitinase 3.2.1.14 Trichoderma viride (VARIOUS STRAINS) AAF19618.1
AAF19613.1
AAF19619.1
AAF19621.1
AAF19622.1
Q9UV39
Q9UV40
Q9UV42
Q9UV43
Q9UV48
 
 chitinase (Chi42) 3.2.1.14 Trichoderma viride LTR-2 ABR27743.1 A6YNL9  
 chitinase (TYchi) 3.2.1.14 Trichosanthes kirilowii AAL01886.1 Q945U2  
 chitinase (Chi1) 3.2.1.14 Trichothecium roseum ADV02752.1
ADV02751.1
   
 chitinase 3.2.1.14 Trifolium repens CAB65476.2 Q9SC03  
 chitinase 2 3.2.1.14 Tulipa bakeri   Q7M443  
 chitinase 3.2.1.14 Turritis glabra BAA21876.1 O22075  
 chitinase 3.2.1.14 uncultured Neotyphodium AAP49451.1 Q7Z9Z5  
 chitinase (Cts1;Um10419) 3.2.1.14 Ustilago maydis AAG35111.1    
 chitinase A 3.2.1.14 Vigna angularis BAA01948.1 P29024  
 acidic chitinase 3 (Chi3A) 3.2.1.14 Vigna unguiculata CAA61280.1 Q43683  
 chitinase 3.2.1.14 Vigna unguiculata CAA61279.1 Q43684  
 chitinase III (Chit3;Chi-III) 3.2.1.14 Vitis vinifera CAA92207.1
BAC65326.1
P51614
Q84S31
 
 chitinase (Chit3; VITISV_035040) 3.2.1.14 Vitis vinifera CAC14016.1
CAN64487.1
Q9FS44  
 endochitinase 3.2.1.14 Wuchereria bancrofti AAF66988.1 Q9NGK8  
 endochitinase (Zm.9675;ChiIVA;ChiIII9675;LOC100285638;ZM_BFc0133D17) 3.2.1.14 Zea mays B73 ACG45330.1
ACF88258.1
B4G1L5
B6U7J7
 
Viruses
Protein Name EC#OrganismGenBank UniprotPDB/3D
 chitinase (ChiA;ACNVgp127) 3.2.1.14 Autographa californica nucleopolyhedrovirus NP_054156.1 P41684  
 chitinase (ChiA;bAcMK128) 3.2.1.14 Autographa californica nucleopolyhedrovirus C6 AGQ56829.1 P41684  
 chitinase (ChiA;Chi-A;orf126;BmNPVgp110) 3.2.1.14 Bombyx mori nucleopolyhedrovirus T3 AAC63792.1
NP_047523.1
O92482  
 chitinase 3.2.1.14 Choristoneura fumiferana multiple nucleopolyhedrovirus AAB68594.1 O41478
Q6LCC0
 
 chitinase (ChiA;Chi;ORF10) 3.2.1.14 Cydia pomonella granulosis virus (isolate Mexican) AAK70677.1
BAA31200.1
NP_148794.1
O91465  
 chitinase (Chi;DkChi) 3.2.1.14 Dendrolimus kikuchii nucleopolyhedrovirus AFP66961.1    
 exochitinase (Chi;Orf110) 3.2.1.14 Epiphyas postvittana nucleopolyhedrovirus AAK85674.1
NP_203279.1
Q91GE4  
 chitinase 3.2.1.14 Helicoverpa armigera nucleopolyhedrovirus AAD22958.1 Q9WFU7  
 chitinase 3.2.1.14 Helicoverpa armigera nucleopolyhedrovirus AAK96293.1
AAK28347.1
NP_203597.1
Q91BX5
Q995W8
 
 chitinase (ChiA) 3.2.1.14 Hyphantria cunea nucleopolyhedrovirus AAD31762.1
BAE72319.1
Q9WGG2  
 chitinase (A260R;PBCV1_A260R) 3.2.1.14 Paramecium bursaria Chlorella virus 1 AAC96628.1
AAC96628.3
AAC97066.2
NP_048613.1
O41019
Q84577
 
 endochitinase (A181/182R;PBCV1_A181/182R) 3.2.1.14 Paramecium bursaria Chlorella virus 1 AAC96549.2
AAC96549.3
NP_048529.1
Q84501  
 endochitinase (A181/182R;PBCV1_A181/182R) 3.2.1.14 Paramecium bursaria Chlorella virus 1 AAC96549.2
AAC96549.3
NP_048529.1
Q84501  
 chitinase (vChti-1) 3.2.1.14 Paramecium bursaria Chlorella virus CVK2 BAA78554.1 Q9WAX4  
 chitinase (vChti-1) 3.2.1.14 Paramecium bursaria Chlorella virus CVK2 BAA78554.1 Q9WAX4  
 chitinase A (ChiA) 3.2.1.14 Spodoptera litura nucleopolyhedrovirus AGN92862.1    
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