Glycoside Hydrolase Family 18

Activities in Familychitinase (EC 3.2.1.14); lysozyme (EC 3.2.1.17); endo-β-N-acetylglucosaminidase (EC 3.2.1.96); peptidoglycan hydrolase with endo-β-N-acetylglucosaminidase specificity (EC 3.2.1.-); Nod factor hydrolase (EC 3.2.1.-); xylanase inhibitor; concanavalin B; narbonin
Mechanism Retaining
ClanGH-K
3D Structure Status( β / α ) 8
Catalytic Nucleophile/Basecarbonyl oxygen of C-2 acetamido group of substrate
Catalytic Proton DonorGlu (experimental)
NoteContains chitinases of classes III and V. Contains non-catalytic proteins such as xylanase inhibitor; concanavalin B; narbonin
External resourcesCAZypedia; HOMSTRAD; PROSITE;
Commercial Enzyme Provider(s)NZYTech; PROZOMIX;
Statistics GenBank accession (14721); Uniprot accession (3282); PDB accession (301); 3D entries (77); cryst (4)
All (13178) Archaea (61) Bacteria (9567) Eukaryota (3057) Viruses (256) unclassified (237) Structure (77 - 4 cryst) Characterized (477)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Kcr_0727   Candidatus Korarchaeum cryptofilum OPF8 ACB07477.1 B1L4U8  
 Vng0818c   Halobacterium salinarum NRC-1 AAG19275.1
NP_279795.1
Q9HR83  
 chitinase (ChiN1;Chi;VNG_0816G;Vng0816g) 3.2.1.14 Halobacterium salinarum NRC-1 AAG19274.1
NP_279794.1
Q9HR84  
 chitinase (Chia1;HsChiA1;OE2201F) 3.2.1.14 Halobacterium salinarum R1 CAP13543.1 B0R478  
 OE2205F (Chia2)   Halobacterium salinarum R1 CAP13544.1 B0R479  
 BM92_18815   Haloferax mediterranei ATCC 33500 AHZ24256.1    
 BM92_18825   Haloferax mediterranei ATCC 33500 AHZ24258.1    
 BM92_18820   Haloferax mediterranei ATCC 33500 AHZ24257.1    
 BM92_18810   Haloferax mediterranei ATCC 33500 AHZ24255.1    
 HFX_5038 (ChiCHme) 3.2.1.14 Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK20875.1    
 HFX_5037 (ChiBHme) 3.2.1.14 Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK20874.1    
 HFX_5039 (ChiDHme) 3.2.1.14 Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK20876.1    
 HFX_5036 (ChiAHme) 3.2.1.14 Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK20873.1    
 Hbor_35560   Halogeometricum borinquense DSM 11551 ADQ69076.1 E4NV87  
 Hbor_35570   Halogeometricum borinquense DSM 11551 ADQ69077.1 E4NV88  
 Hbor_35580   Halogeometricum borinquense DSM 11551 ADQ69078.1 E4NV89  
 Hbor_35590   Halogeometricum borinquense DSM 11551 ADQ69079.1 E4NV90  
 Hmuk_2923   Halomicrobium mukohataei DSM 12286 ACV49028.1 C7P113  
 Hmuk_1493   Halomicrobium mukohataei DSM 12286 ACV47608.1 C7P3D6  
 Hmuk_2924   Halomicrobium mukohataei DSM 12286 ACV49029.1 C7P114  
 Hmuk_2922   Halomicrobium mukohataei DSM 12286 ACV49027.1 C7P112  
 Hmuk_3148   Halomicrobium mukohataei DSM 12286 ACV49253.1 C7P2D8  
 Hmuk_0883   Halomicrobium mukohataei DSM 12286 ACV47013.1 C7P0N1  
 Hmuk_2921   Halomicrobium mukohataei DSM 12286 ACV49026.1 C7P111  
 Htur_2175   Haloterrigena turkmenica DSM 5511 ADB61056.1 D2RTV5  
 Mpet_2554   Methanolacinia petrolearia DSM 11571 ADN37298.1 E1RF54  
 Mpet_2554   Methanolacinia petrolearia DSM 11571 ADN37298.1 E1RF54  
 Mboo_2180   Methanoregula boonei 6A8 ABS56694.1 A7IAD3  
 MSBR2_2791   Methanosarcina barkeri 227 AKB59307.1    
 MCM1_2974   Methanosarcina barkeri CM1 AKJ39970.1    
 MSBRM_2833   Methanosarcina barkeri MS AKB55831.1    
 MSLAZ_2062   Methanosarcina lacustris Z-7289 AKB75323.1    
 MSKOL_0880   Methanosarcina sp. Kolksee AKB46657.1    
 MSKOL_0005   Methanosarcina sp. Kolksee AKB45782.1    
 MSVAZ_0911   Methanosarcina vacuolata Z-761 AKB43180.1    
 MSVAZ_0021   Methanosarcina vacuolata Z-761 AKB42290.1    
 NJ7G_2699 (Chi1)   Natrinema sp. J7-2 AFO57928.1    
 NJ7G_2700 (Chi2)   Natrinema sp. J7-2 AFO57929.1
AFO57929.2
   
 NJ7G_2701 (fragment)   Natrinema sp. J7-2 AFO57930.1    
 NJ7G_2702 (Chi3) (fragment)   Natrinema sp. J7-2 AFO57931.1    
 PFC_05385 (fragment)   Pyrococcus furiosus COM1 AFN04020.1    
 PFC_05385 (fragment)   Pyrococcus furiosus COM1 AFN04020.1    
 PFC_05390 (fragment)   Pyrococcus furiosus COM1 AFN04021.1    
 chitinase (PF1234+PF1233;ChiA+ChiB) (Chi18B+Chi18A) 3.2.1.14
3.2.1.14
Pyrococcus furiosus DSM 3638 AAL81357.1
AAL81358.1
NP_578962.1
NP_578963.1
Q8U1H4
Q8U1H5
 
 chitinase (PF1234+PF1233;ChiA+ChiB) (Chi18B+Chi18A) 3.2.1.14
3.2.1.14
Pyrococcus furiosus DSM 3638 AAL81357.1
NP_578962.1
Q8U1H5 2DSK[A,B]
3A4W[A,B]
3A4X[A,B]
 L593_04100   Salinarchaeum sp. Harcht-Bsk1 AGN00771.1    
 L593_04105   Salinarchaeum sp. Harcht-Bsk1 AGN00772.1    
 L593_04110   Salinarchaeum sp. Harcht-Bsk1 AGN00773.1    
 L593_10665   Salinarchaeum sp. Harcht-Bsk1 AGN02078.1    
 L593_10660   Salinarchaeum sp. Harcht-Bsk1 AGN02077.1    
 chitinase (ChiC;CHITON_1716)   Thermococcus chitonophagus DSM 10152 BAU88508.1
CUX78495.1
   
 chitinase A (ChiA;CHITON_1717) 3.2.1.14 Thermococcus chitonophagus DSM 10152 CUX78496.1
AAR13021.1
BAU88507.1
Q6T390  
 chitinase A (ChiA;CHITON_1717) 3.2.1.14 Thermococcus chitonophagus DSM 10152 CUX78496.1
AAR13021.1
BAU88507.1
Q6T390  
 A3L04_07955   Thermococcus chitonophagus GC74 ASJ17008.1    
 A3L04_07960   Thermococcus chitonophagus GC74 ASJ17009.1    
 chitinase A (ChiA;TK1765) 3.2.1.14
3.2.1.-
Thermococcus kodakarensis KOD1 BAD85954.1
CAT70561.1
Q9UWR7  
 chitinase A (ChiA;TK1765) 3.2.1.14
3.2.1.-
Thermococcus kodakarensis KOD1 BAD85954.1
CAT70561.1
Q9UWR7  
 BD01_1064   Thermococcus nautili 30-1 AHL22681.1    
 BD01_1065   Thermococcus nautili 30-1 AHL22682.1    
 BD01_1065   Thermococcus nautili 30-1 AHL22682.1    
 BD01_1065   Thermococcus nautili 30-1 AHL22682.1    
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