Glycoside Hydrolase Family 181

Activities in FamilyExo-α-sialidase (EC 3.2.1.18);
Mechanism Inverting e
3D Structure Status6-fold β-propeller
NoteCreated after Shuoker et al. (2023) [PMID= 37005422] who demonstrated the exo-a-sialidase activity of the Amuc_1547 protein from Akkermansia muciniphila and solved its 3D structure.
Statistics GenBank accession (196); Uniprot accession (0); PDB accession (3); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 exo-α-sialidase / neuraminidase (AmGH181; Amuc_1547; Am1757) 3.2.1.18 pubmed
Akkermansia muciniphila ATCC BAA-835 ACD05368.1
QTD80088.1
  8AXI[A,B]
8AXS[A,B]
8AXT[A,B]
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