Glycoside Hydrolase Family 16

Activities in Familyxyloglucan:xyloglucosyltransferase (EC; keratan-sulfate endo-1,4-β-galactosidase (EC; endo-1,3-β-glucanase / laminarinase (EC; endo-1,3(4)-β-glucanase (EC; licheninase (EC; β-agarase (EC; κ-carrageenase (EC; xyloglucanase (EC; endo-β-1,3-galactanase (EC; [retaining] β-porphyranase (EC; hyaluronidase (EC; endo-β-1,4-galactosidase (EC 3.2.1.-); chitin β-1,6-glucanosyltransferase (EC 2.4.1.-); β-transglycosidase (EC 2.4.1.-); β-glycosidase (EC 3.2.1.-); endo-β-1,3-galactanase (EC; β-carrageenase (EC 3.2.1.-); β-carrageenase (EC 3.2.1.-);
Mechanism Retaining
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
NoteMany members have been assigned to subfamilies as described by Viborg et al. (2019) J Biol Chem. 2019 Sep 9 (PMID: 31501245).
External resourcesCAZypedia; HOMSTRAD; PRINTS; PROSITE; XTH-World;
Commercial Enzyme Provider(s)MEGAZYME; NZYTech; PROZOMIX;
Statistics GenBank accession (9993); Uniprot accession (1506); PDB accession (95); 3D entries (47); cryst (1)
All (8752) Archaea (26) Bacteria (5475) Eukaryota (3184) Viruses (54) unclassified (13) Structure (47 - 1 cryst) Characterized (214)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ... | 55 |
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 AM1_3194   Acaryochloris marina MBIC11017 ABW28190.1 B0CET5  
 NCTC10138_01103 (Bgla_2)   Acholeplasma axanthum NCTC10138 VEU80723.1     3
 NCTC10138_01091 (Bgla_1)   Acholeplasma axanthum NCTC10138 VEU80711.1     3
 BN85307910   Acholeplasma brassicae O502 CCV65812.1     3
 BN85308030 (BglA)   Acholeplasma brassicae O502 CCV65824.1     3
 BN85312350   Acholeplasma brassicae O502 CCV66256.1     3
 NCTC10116_00734 (Bgla_2)   Acholeplasma laidlawii NCTC10116 SQH56944.1     3
 NCTC10116_01073 (LicB)   Acholeplasma laidlawii NCTC10116 SQH57268.1    
 NCTC10116_00724 (Bgla_1)   Acholeplasma laidlawii NCTC10116 SQH56934.1     3
 ACL_0717   Acholeplasma laidlawii PG-8A ABX81333.1 A9NG53   3
 ACL_0727   Acholeplasma laidlawii PG-8A ABX81343.1 A9NG63   3
 ACL_1063   Acholeplasma laidlawii PG-8A ABX81673.1 A9NH43  
 Aocu_07860   Acholeplasma oculi CDR30859.1     3
 Aocu_07960   Acholeplasma oculi CDR30869.1     3
 ACPOL_1352   Acidisarcina polymorpha SBC82 AXC10700.1     3
 ACPOL_3286   Acidisarcina polymorpha SBC82 AXC12579.1    
 LuPra_03163 (BglA)   Acidobacteria bacterium DSM 100886 AMY09936.1     3
 ACP_3489 (BglA)   Acidobacterium capsulatum ATCC 51196 ACO33098.1 C1F719   3
 Acel_0129   Acidothermus cellulolyticus 11B ABK51904.1 A0LR44   3
 C8243_14840   Acidovorax avenae subsp. avenae NCT3 AVT03625.1    
 UA74_13920   Actinoalloteichus fjordicus ADI127-7 APU14842.1     3
 UA74_18340   Actinoalloteichus fjordicus ADI127-7 APU15696.1     10
 AHOG_13090 (Bgla1)   Actinoalloteichus hoggarensis DSM 45943 ASO20261.1     3
 AHOG_16295   Actinoalloteichus hoggarensis DSM 45943 ASO20885.1     10
 TL08_15200   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS63849.1     10
 TL08_13050   Actinoalloteichus hymeniacidonis HPA177(T) (=DSM 45092(T)) AOS63424.1     3
 C1701_17620   Actinoalloteichus sp. AHMU CJ021 AUS79845.1     3
 UA75_18830   Actinoalloteichus sp. GBA129-24 APU21756.1     10
 UA75_14005   Actinoalloteichus sp. GBA129-24 APU20811.1     3
 NCTC12972_00798 (BglA)   Actinomyces israelii NCTC12972 VEG53774.1    
 NCTC12972_01876   Actinomyces israelii NCTC12972 VEG55954.1    
 AN27039_2609 (fragment)   Actinomyces naeslundii ATCC 27039 BAV85679.1    
 AXE84_10835   Actinomyces oris T14V AMD99846.1    
 CHIBA101_2000   Actinomyces sp. Chiba101 BAW93832.1    
 FBF36_07060   Actinomyces sp. oral taxon 171 str. F0337 QCT33245.1    
 FBF36_02435   Actinomyces sp. oral taxon 171 str. F0337 QCT32466.1    
 BK816_08205   Actinomyces tangfeifanii VUL4_3 AOZ73267.1    
 BK816_07345   Actinomyces tangfeifanii VUL4_3 AOZ73128.1    
 NCTC10951_00748 (ExsH)   Actinomyces viscosus NCTC10951 VEI14872.1    
 SAMN04489716_3019   Actinoplanes derwentensis DSM 43941 SDT25471.1     3
 SAMN04489716_2237   Actinoplanes derwentensis DSM 43941 SDT00724.1    
 SAMN04489716_7826   Actinoplanes derwentensis DSM 43941 SDT77088.1     3
 SAMN04489716_3348   Actinoplanes derwentensis DSM 43941 SDT33716.1    
 AFR_10820   Actinoplanes friuliensis DSM 7358 AGZ40453.1     3
 AFR_23560   Actinoplanes friuliensis DSM 7358 AGZ42982.1     21
 AFR_33795   Actinoplanes friuliensis DSM 7358 AGZ45017.1     3
 AFR_38190   Actinoplanes friuliensis DSM 7358 AGZ45892.1     3
 AFR_13795   Actinoplanes friuliensis DSM 7358 AGZ41045.1    
 AFR_32085   Actinoplanes friuliensis DSM 7358 AGZ44675.1     3
 AFR_32590   Actinoplanes friuliensis DSM 7358 AGZ44776.1     3
 AFR_38185   Actinoplanes friuliensis DSM 7358 AGZ45891.1    
 AFR_42535   Actinoplanes friuliensis DSM 7358 AGZ46761.1    
 AMIS_72550   Actinoplanes missouriensis 431 BAL92475.1     3
 AMIS_73120   Actinoplanes missouriensis 431 BAL92532.1     3
 AMIS_73110 (fragment)   Actinoplanes missouriensis 431 BAL92531.1    
 AMIS_38790   Actinoplanes missouriensis 431 BAL89099.1     3
 AMIS_38340   Actinoplanes missouriensis 431 BAL89054.1    
 AMIS_38780   Actinoplanes missouriensis 431 BAL89098.1     3
 L083_3578   Actinoplanes sp. N902-109 AGL17088.1     3
 L083_6514   Actinoplanes sp. N902-109 AGL20024.1     3
 L083_7169   Actinoplanes sp. N902-109 AGL20679.1     3
 L083_7236 (GlcA)   Actinoplanes sp. N902-109 AGL20746.1     3
 L083_2909   Actinoplanes sp. N902-109 AGL16419.1    
 L083_6264   Actinoplanes sp. N902-109 AGL19774.1     3
 L083_6467   Actinoplanes sp. N902-109 AGL19977.1    
 L083_7235   Actinoplanes sp. N902-109 AGL20745.1    
 ACTI_49840   Actinoplanes sp. OR16 BBH68299.1    
 ACTI_57360   Actinoplanes sp. OR16 BBH69051.1    
 ACTI_56890   Actinoplanes sp. OR16 BBH69004.1    
 ACTI_57370   Actinoplanes sp. OR16 BBH69052.1     3
 ACTI_13210 (fragment)   Actinoplanes sp. OR16 BBH64636.1    
 ACTI_13220   Actinoplanes sp. OR16 BBH64637.1     3
 ACTI_12680   Actinoplanes sp. OR16 BBH64583.1     3
 ACWT_3117   Actinoplanes sp. SE50 ATO82532.1     3
 ACWT_1510   Actinoplanes sp. SE50 ATO80925.1    
 ACWT_7393   Actinoplanes sp. SE50 ATO86808.1     3
 ACWT_4834   Actinoplanes sp. SE50 ATO84249.1     3
 ACWT_2719   Actinoplanes sp. SE50 ATO82134.1     3
 ACWT_7448   Actinoplanes sp. SE50 ATO86863.1     3
 ACPL_2827   Actinoplanes sp. SE50/110 AEV83722.1
 ACPL_3245 (GlcA)   Actinoplanes sp. SE50/110 AEV84140.1
 ACPL_7523 (BglA)   Actinoplanes sp. SE50/110 AEV88403.1
 ACPL_7578   Actinoplanes sp. SE50/110 AEV88458.1
 ACPL_1632   Actinoplanes sp. SE50/110 AEV82529.1
 ACPL_4964   Actinoplanes sp. SE50/110 AEV85853.1
 SAMN04489717_4293   Actinopolymorpha singaporensis DSM 22024 SDS90535.1    
 CDG81_16980   Actinopolyspora erythraea YIM 90600 ASU79683.1     3
 Amir_1077   Actinosynnema mirum DSM 43827 ACU35033.1 C6WPX7   3
 Amir_5321   Actinosynnema mirum DSM 43827 ACU39141.1 C6W969   3
 Amir_5074   Actinosynnema mirum DSM 43827 ACU38896.1 C6WS76   10
 Amir_6912   Actinosynnema mirum DSM 43827 ACU40707.1 C6WR14  
 APASM_6848   Actinosynnema pretiosum subsp. pretiosum ATCC 31280 AXX34213.1    
 APASM_5374   Actinosynnema pretiosum subsp. pretiosum ATCC 31280 AXX32739.1     3
 APASM_1041   Actinosynnema pretiosum subsp. pretiosum ATCC 31280 AXX28406.1     3
 APASM_5123   Actinosynnema pretiosum subsp. pretiosum ATCC 31280 AXX32488.1     10
 CNX65_05415   Actinosynnema pretiosum X47 ATE52790.1     3
 CNX65_15355   Actinosynnema pretiosum X47 ATE54498.1    
 CNX65_34160   Actinosynnema pretiosum X47 ATE57730.1    
 CNX65_25225   Actinosynnema pretiosum X47 ATE56170.1     10
 CNX65_26500   Actinosynnema pretiosum X47 ATE56384.1     3

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