Activities in Sub Family	[retaining] β-porphyranase (EC 3.2.1.178); β-agarase (EC 3.2.1.81);
Mechanism	Retaining e
Clan	GH-B
3D Structure Status	β-jelly roll
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	Many members have been assigned to subfamilies as described by Viborg et al. (2019) J Biol Chem. 2019 Sep 9 (PMID: 31501245).
External resources	CAZypedia; HOMSTRAD; PRINTS; PROSITE; XTH-World;
Commercial Enzyme Provider(s)	MEGAZYME; NZYTech; PROZOMIX;
Statistics	GenBank accession (256); Uniprot accession (40); PDB accession (10); 3D entries (7); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
Glycoside hydrolase		Aquimarina sp.			7FGZ[A] 2.20	16
endo-β-agarase (NP1_8; BuGH16B)	3.2.1.81	Bacteroides uniformis NP1			5T9X[B,C] 2.50 5T9X[A] 2.50	16
β-agarase (AgaA; MtAgaA)	3.2.1.81	Microbulbifer thermotolerans JAMB-A94	BAD29947.1 BAK08910.1	Q6F4N4	3WZ1[A] 1.60	16
neoagarabiose-producing β-agarase (PdAgaC)	3.2.1.81	Persicobacter sp. CCB-QB2	WP_053404800.1	A0A5S8WF47	6AII[A] 1.63	16
β-agarase D (AgaD;zobellia_4243)	3.2.1.81	Zobellia galactanivorans DsijT	CAZ98378.1 CBM41186.1	D7GXG4	4ASM[B] 1.50	16
β-agarase B (AgaB; ZgAgaB; zobellia_3573)	3.2.1.81	Zobellia galactanivorans DsijT	CAZ97711.1 AAF21821.1 AAO99183.1 CAC07427.1	Q9RGX8	1O4Z[A,B,C,D] 2.30 4ATF[A,B,C,D] α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp 1.90	16
β-agarase A (AgaA; zobellia_4203)	3.2.1.81	Zobellia galactanivorans DsijT	CAZ98338.1 AAF21820.1 AAO99182.1 AAO99184.1 CAC07425.1	G0L322 Q9RGX9	1O4Y[A] 1.48 1URX[A] α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp-(1-3)-β-D-Galp-(1-4)-α-L-3,6-anhydro-Galp 1.7	16
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