Glycoside Hydrolase Family 161

Activities in Familyβ-1,3-glucan phosphorylase (EC 2.4.1.97)
Mechanism inverting
ClanGH-Q
3D Structure Status( α / α ) 6 (inferred)
Catalytic Nucleophile/Basephosphate
Catalytic Proton DonorAsp (inferred)
NoteFamily created after Kuhaudomlarp et al. J. Biol. Chem. (2019) [PMID=30819804] who have shown that the Paenibacillus polymyxa ATCC 842 and Thermosipho africanus TCF52B enzymes are b-1,3-glucan phosphorylases, distantly related to GH149. Hence this family integrates the clan GH-Q with family GH94 and GH149.
Statistics GenBank accession (166); Uniprot accession (2);
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 β-1,3-glucan phosphorylase (PPT_RS0121460; PapP) 2.4.1.97 pubmed
Paenibacillus polymyxa ATCC 842 WP_019688419.1 A0A378Y2K9  
 β-1,3-glucan phosphorylase (THA_1941; TaCDP) 2.4.1.97 pubmed
Thermosipho africanus TCF52B ACJ76363.1 B7IED6  
Eukaryota
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 1,3-β-glucan phosphorylase (OdBGP) 2.4.1.97 pubmed
Ochromonas danica NIES-2142 BAU78234.1    
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