Glycoside Hydrolase Family 161

Activities in Familyβ-1,3-glucan phosphorylase (EC 2.4.1.97)
Mechanism inverting
ClanGH-Q
3D Structure Status( α / α ) 6 (inferred)
Catalytic Nucleophile/Basephosphate
Catalytic Proton DonorAsp (inferred)
NoteFamily created after Kuhaudomlarp et al. J. Biol. Chem. (2019) [PMID=30819804] who have shown that the Paenibacillus polymyxa ATCC 842 and Thermosipho africanus TCF52B enzymes are b-1,3-glucan phosphorylases, distantly related to GH149. Hence this family integrates the clan GH-Q with family GH94 and GH149.
Statistics GenBank accession (129); Uniprot accession (0);
All (128) Archaea (12) Bacteria (115) Eukaryota (1) Characterized (2)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-1,3-glucan phosphorylase (PPT_RS0121460; PapP) 2.4.1.97 Paenibacillus polymyxa ATCC 842 WP_019688419.1    
 β-1,3-glucan phosphorylase (THA_1941; TaCDP) 2.4.1.97 Thermosipho africanus TCF52B ACJ76363.1    
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