Activities in Family	glucoamylase (EC 3.2.1.3); glucodextranase (EC 3.2.1.70); α,α-trehalase (EC 3.2.1.28); dextran dextrinase (EC 2.4.1.2)
Mechanism	Inverting
Clan	GH-L
3D Structure Status	( α / α ) 6 barrel
Catalytic Nucleophile/Base	Glu (experimental)
Catalytic Proton Donor	Glu (experimental)
External resources	CAZypedia; Glucoamylase Page; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)	MEGAZYME;
Statistics	GenBank accession (8567); Uniprot accession (715); PDB accession (25); 3D entries (10); cryst (1)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
glucodextranase (G1d)	3.2.1.70	Arthrobacter globiformis I42	BAA90671.1 BAB20416.1	Q9LBQ9	1UG9[A] 1.65 1ULV[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-D-1-deoxy-Glcp 1.80
α-1,6-glucosidase / isomaltase (Kfla_1896)	3.2.1.205	Kribbella flavida DSM 17836	ADB30990.1	D2PPM8	5Z3A[A] 1.57 5Z3B[A] 1.65 5Z3C[A] 2.21 5Z3D[A] 2.00 5Z3E[A] 1.70 5Z3F[A] β-D-Glcp 1.40
glucoamylase (TGA)	3.2.1.3	Thermoactinomyces vulgaris R-47	BAA97041.1 BAB40639.1	Q9KWR2	cryst
glucoamylase (Ga1)	3.2.1.3	Thermoanaerobacterium thermosaccharolyticum ATCC 7956	AAC24003.1 ABJ38330.1 ACW20095.1	O85672	1LF6[A] 1.99 1LF9[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 1.90
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
glucoamylase P (GamP)	3.2.1.3	Amorphotheca resinae ATCC 20495	CAA47945.1 CAA48243.1 CAY05396.1	Q03045	6FHW[A,B] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 2.80
glucoamylase (Gla)	3.2.1.3	Aspergillus awamori X-100	AAB02927.1 CAY05380.1	Q12537	1AGM[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 1.92 1DOG[A] <carb_like_NOJ> 1.04 1GAH[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 1.26 1GAI[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp 1.36 1GLM[A] 1.65 3GLY[A] 2.21
glucoamylase (GlaA;An03g06550)	3.2.1.3	Aspergillus niger CBS 513.88	CAK38411.1 AAE51533.1 AAP60775.1 AAQ77828.1 AAR61399.1 AAT67041.1 ABH92240.1 ABH92241.1 ABL16522.1 ABL22839.1 ACJ91357.1 ACP59407.1 ADX86749.1 AEE60909.1 CAA25219.1 CAA25303.1 CAA25304.1 CAC22383.1 CAC28418.1 CAX21649.1 CAY05387.1	A2QHE1 P69328 Q6DNH5	3EQA[A] 2.40 6FRV[A] 1.60
glucoamylase (PoGA;PDE_05527)	3.2.1.3	Penicillium oxalicum 114-2	EPS30575.1		6FHV[A] 1.50
glucoamylase (Glu;Glu1)	3.2.1.3	Saccharomycopsis fibuligera HUT 7212	AAA34649.1 AAA83997.1 CAY05397.1	P08017	1AYX[A] 2.00 2F6D[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp 2.30 2FBA[A] 2.10
glucoamylase (GA)	3.2.1.3	Trichoderma reesei	AAB34091.1 ACP59416.1		2VN4[A] 3.0 2VN7[A] 1.80
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