Glycoside Hydrolase Family 15

Activities in Familyglucoamylase (EC 3.2.1.3); glucodextranase (EC 3.2.1.70); α,α-trehalase (EC 3.2.1.28); dextran dextrinase (EC 2.4.1.2)
Mechanism Inverting
ClanGH-L
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; Glucoamylase Page; HOMSTRAD; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (4278); Uniprot accession (715); PDB accession (16); 3D entries (7); cryst (1)
All (4054) Archaea (347) Bacteria (3363) Eukaryota (331) unclassified (13) Structure (7 - 1 cryst) Characterized (64)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 glucodextranase (G1d) 3.2.1.70 Arthrobacter globiformis I42 BAA90671.1
BAB20416.1
Q9LBQ9
1UG9[A] 2.50
1ULV[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-D-1-deoxy-Glcp
2.42
 glucoamylase (TGA) 3.2.1.3 Thermoactinomyces vulgaris R-47 BAA97041.1
BAB40639.1
Q9KWR2
cryst    
 glucoamylase (Ga1) 3.2.1.3 Thermoanaerobacterium thermosaccharolyticum ATCC 7956 AAC24003.1
ABJ38330.1
ACW20095.1
O85672
1LF6[A] 2.10
1LF9[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
2.20
Eukaryota
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 glucoamylase (Gla) 3.2.1.3 Aspergillus awamori X-100 AAB02927.1
CAY05380.1
Q12537
1AGM[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
2.30
1DOG[A] <carb_like_NOJ>
2.30
1GAH[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
2.00
1GAI[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-α-D-Glcp
1.70
1GLM[A] 2.40
3GLY[A] 2.20
 glucoamylase (GlaA;An03g06550) 3.2.1.3 Aspergillus niger CBS 513.88 CAK38411.1
AAE51533.1
AAP60775.1
AAQ77828.1
AAR61399.1
AAT67041.1
ABH92240.1
ABH92241.1
ABL16522.1
ABL22839.1
ACJ91357.1
ACP59407.1
ADX86749.1
AEE60909.1
CAA25219.1
CAA25303.1
CAA25304.1
CAC22383.1
CAC28418.1
CAX21649.1
CAY05387.1
A2QHE1
P69328
Q6DNH5
3EQA[A] 1.90
 glucoamylase (Glu;Glu1) 3.2.1.3 Saccharomycopsis fibuligera HUT 7212 AAA34649.1
AAA83997.1
CAY05397.1
P08017
1AYX[A] 1.70
2F6D[A] <non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp
1.60
2FBA[A] 1.10
 glucoamylase (GA) 3.2.1.3 Trichoderma reesei AAB34091.1
ACP59416.1
 
2VN4[A] 1.85
2VN7[A] 1.90
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