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Glycoside Hydrolase Family 15

Known Activitiesglucoamylase (EC 3.2.1.3); glucodextranase (EC 3.2.1.70); α,α-trehalase (EC 3.2.1.28)
Mechanism Inverting
ClanGH-L
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
External resourcesCAZypedia; Glucoamylase Page; HOMSTRAD; InterPro; PFAM; PRINTS; PROSITE;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (1231); Uniprot accession (688); PDB accession (16); 3D entries (7); cryst (1)
Summary
All (1048) Archaea (162) Bacteria (738) Eukaryota (138) unclassified (10) Structure (7 - 1 cryst) Characterized (61)
Archaea
Protein Name EC#OrganismGenBankUniprotPDB/3D
 glucoamylase (MJ1610) 3.2.1.3 Methanocaldococcus jannaschii DSM 2661 AAB99630.1
NP_248620.1		 Q59005  
 glucoamylase (PTO1492) 3.2.1.3 Picrophilus torridus DSM 9790 AAT44077.1 Q6KYX5  
 glucoamylase (PTO0365) 3.2.1.3 Picrophilus torridus DSM 9790 AAT42950.1 Q6L252  
 glucoamylase (Ssg;Sso0990) 3.2.1.3 Sulfolobus solfataricus P2 AAK41262.1
NP_342472.1		 Q97ZD0  
 glucoamylase (STGA;ST0815) 3.2.1.3 Sulfolobus tokodaii str. 7 BAB65828.1
BAK54392.1
NP_376719.1		 Q973T2  
 glucoamylase (TaGA;Ta0342) 3.2.1.3 Thermoplasma acidophilum DSM 1728 CAC11486.1
NP_393821.1		 Q9HL88  
Bacteria
Protein Name EC#OrganismGenBankUniprotPDB/3D
 glucodextranase (G1d) 3.2.1.70 Arthrobacter globiformis I42 BAA90671.1
BAB20416.1		 Q9LBQ9 1UG9[A]
1ULV[A]
 glucodextranase (Gld) 3.2.1.70 Arthrobacter globiformis T-3044 BAA13597.1 P70745  
 glucoamylase (CGA) 3.2.1.3 Clostridium sp. G0005 BAA02251.1 P29761.1  
 glucoamylase 3.2.1.3 Clostridium thermoamylolyticum BAC80264.2 Q765N4  
 glucoamylase (GamA;LegY;lpp0489) 3.2.1.3 Legionella pneumophila str. Paris CAH11637.1 Q5X7W6  
 α,α-trehalase (MSMEG_4535;MSMEG4528) 3.2.1.28 Mycobacterium smegmatis str. MC2 155 ABK72415.1 A0R0W9  
 glucoamylase (VldI) 3.2.1.3 Streptomyces hygroscopicus subsp. limoneus KCCM 11405 ABC67273.1 Q15JF7  
 glucoamylase (TGA) 3.2.1.3 Thermoactinomyces vulgaris R-47 BAA97041.1
BAB40639.1		 Q9KWR2 cryst
 glucoamylase (GA;TTE1813) 3.2.1.3 Thermoanaerobacter tengcongensis MB4 AAM25005.1
NP_623401.1		 Q8R917  
 glucoamylase (Ga1) 3.2.1.3 Thermoanaerobacterium thermosaccharolyticum ATCC 7956 AAC24003.1
ABJ38330.1
ACW20095.1		 O85672 1LF6[A]
1LF9[A]
Eukaryota
Protein Name EC#OrganismGenBankUniprotPDB/3D
 glucoamylase P (GamP) 3.2.1.3 Amorphotheca resinae CAA47945.1
CAA48243.1
CAY05396.1		 Q03045  
 glucoamylase (GaA;Arx) 3.2.1.3 Arxula adeninivorans CAA86997.1 P42042  
 glucoamylase (GA I) 3.2.1.3 Aspergillus awamori KT-11 BAD06004.1
CAY05390.1		 Q76L97  
 glucoamylase G1 (GlaA) 3.2.1.3 Aspergillus awamori NRRL 3112 AAB59296.1
AAB59297.1
AEI58995.1		 P04064
P69327		  
 glucoamylase (Gla) 3.2.1.3 Aspergillus awamori X-100 AAB02927.1
CAY05380.1		 Q12537 1AGM[A]
1DOG[A]
1GAH[A]
1GAI[A]
1GLM[A]
3GLY[A]
 glucoamylase (GluA-G) 3.2.1.3 Aspergillus ficuum HENNINAS 3.432 AAT58037.1
CAY05388.1		 Q6DUY5  
 glucoamylase (GaI) 3.2.1.3 Aspergillus kawachii BAA00331.1 P23176.1  
 glucoamylase (GlaA;An03g06550) 3.2.1.3 Aspergillus niger CBS 513.88 AAE51533.1
AAP60775.1
AAQ77828.1
AAR61399.1
AAT67041.1
ABH92240.1
ABH92241.1
ABL16522.1
ABL22839.1
ACJ91357.1
ACP59407.1
ADX86749.1
AEE60909.1
CAA25219.1
CAA25303.1
CAA25304.1
CAC22383.1
CAC28418.1
CAK38411.1
CAX21649.1
CAY05387.1		 A2QHE1
P69328.1
Q6DNH5		 3EQA[A]
 glucoamylase (peptide fragments) 3.2.1.3 Aspergillus niveus URM-WFCC604      
 glucoamylase (GlaB) 3.2.1.3 Aspergillus oryzae O-1013 BAA25205.1
CAY05377.1		 O59846  
 glucoamylase (GlaB;AO090003000321) 3.2.1.3 Aspergillus oryzae RIB40 BAE57516.1    
 glucoamylase (GlaA; AO090010000746) 3.2.1.3 Aspergillus oryzae RIB40 AAB20818.1
ABA62323.1
BAA00841.1
BAA01540.1
BAE66563.1
CAY05395.1		 P36914.2  
 glucoamylase (Gla) 3.2.1.3 Aspergillus shirousami ABJ38329.1
ACW20094.1
BAA01254.1		 P22832.1  
 glucoamylase (Gla1) 3.2.1.3 Aspergillus terreus 4      
 glucoamylase G2 3.2.1.3 Athelia rolfsii AHU9627 ABL22841.1
BAA08436.1
CAI45339.1
CAI45340.1
CAI45341.1
CAI45342.1
CAI45344.1
CAI45345.1
CAT03378.1
CAY05381.1		 Q12596  
 glucoamylase (GLA) 3.2.1.3 Chaetomium thermophilum CT2 ABD96025.1 Q0H9W2  
 glucoamylase / steroidal saponin-rhamnosidase (peptide fragments) 3.2.1.3 Cochliobolus lunatus      
 glucoamylase (Gla1;HfGla1) 3.2.1.3 Cyberlindnera fabianii J640 BAJ21225.1 E1CJT1  
 glucoamylase (GlA) 3.2.1.3 Fomitopsis palustris FFPRI 0507 BAE47183.1 Q33CE4  
 glucoamylase 3.2.1.3 Fusarium venenatum AAM17546.1
AAP00500.1
AAS37043.1		    
 glucoamylase (Gla1) 3.2.1.3 Humicola grisea var. thermoidea NRLL 15219 AAA33386.1
ACC34981.1
CAY05382.1		 Q12623  
 glucoamylase (GA) 3.2.1.3 Hypocrea jecorina AAB34091.1
ACP59416.1		   2VN4[A]
2VN7[A]
 glucoamylase (GLA) 3.2.1.3 Lentinula edodes L54 AAF75523.1 Q9P4C5  
 glucoamylase (Sga1;MGG_01096;MG01096.4) (vacuolar) 3.2.1.3 Magnaporthe grisea 70-15 CAY05367.1
EAA49438.1
XP_368148.1		    
 glucoamylase (GA-I) (peptide fragment) 3.2.1.3 Monascus purpureus RY3410      
 glucoamylase (GA-II) (peptide fragment) 3.2.1.3 Monascus purpureus RY3410      
 glucoamylase (Glα-1;NCU01517.1;B5O22.70) 3.2.1.3 Neurospora crassa OR74A AAE15056.1
AAE15057.1
CAA47707.1
CAB91426.1
XP_327956.1		 P14804.3  
 glucoamylase (peptide fragment) 3.2.1.3 Paecilomyces variotii      
 glucoamylase (RaGa) 3.2.1.3 Rhizopus oryzae 3.2893 ABI75077.1 Q09GR5  
 glucoamylase (AmyB) 3.2.1.3 Rhizopus oryzae NBRC 4785 BAH09873.1 B7XC01  
 glucoamylase (AmyC;RO3G_00127.1) 3.2.1.3 Rhizopus oryzae RA 99-880      
 glucoamylase (AmyD;RO3G_06101.1) 3.2.1.3 Rhizopus oryzae RA 99-880      
 glucoamylase 3.2.1.3 Rhizopus oryzae SAM0034 AAQ18643.1
ABJ38331.1
ACW20096.1
BAA00033.1		 P07683.2
Q7Z7X9		  
 glucoamylase (Sga1;Sga;YIL099W) 3.2.1.3 Saccharomyces cerevisiae S288c AAA35042.1
CAA32071.1
CAA86282.1
CAY05366.1
NP_012167.1		 P08019
P08019.2		  
 glucoamylase S1 (STA1;DEX2;MAL5) (frameshift) 3.2.1.3 Saccharomyces cerevisiae var. diastaticus BAA00332.1
CAA26487.1
CAY05400.1		 P04065.2  
 glucoamylase S2 (STA2) (frameshift) 3.2.1.3 Saccharomyces cerevisiae var. diastaticus AAA20560.1
AAA35107.1
CAY05401.1		 P29760.1  
 glucoamylase (Glu;Glu1) 3.2.1.3 Saccharomycopsis fibuligera HUT 7212 AAA34649.1
AAA83997.1
CAY05397.1		 P08017.1 1AYX[A]
2F6D[A]
2FBA[A]
 glucoamylase (Glu 0111;Glm) 3.2.1.3 Saccharomycopsis fibuligera IFO 0111 CAC83969.1
CAY05393.1		 Q8TFE5  
 glucoamylase (Gla;Gla1) 3.2.1.3 Saccharomycopsis fibuligera KZ CAA41120.1
CAY05399.1		 P26989.2  
 glucoamylase (GAI;GAII) (fragment) 3.2.1.3 Scytalidium thermophilum 15.8      
 glucoamylase (GA) 3.2.1.3 Talaromyces emersonii AAR61398.1
AAR61400.1
ABH92236.1
ABH92239.1
ABH92242.1
ABL22840.1
CAC28076.1
CAY05394.1		 Q9C1V4  
 glucoamylase 3.2.1.3 Thermoascus crustaceus      
 glucoamylase (fragment) 3.2.1.3 Thermomucor indicae-seudaticae      
 glucoamylase (Gla1) 3.2.1.3 Thermomyces lanuginosus AAX49506.1
ABQ23180.1
CAY05385.1		 Q58HN1  
 glucoamylase (GlaA) 3.2.1.3 Thielavia terrestris ATCC20627 AAE85601.1    

Footnotes

Experimental characterization exclusively covers enzyme activities at present. If you are aware of any missing experimental characterization that should be mentioned here, we encourage you to send your comment and support of the experimental evidence, including an electronic copy or appropriate link to the support material (i.e., article(s), thesis, database, etc), to cazy@afmb.univ-mrs.fr.





Last update: 2012-01-31 © Copyright 1998-2012
AFMB - CNRS - Universités Aix-Marseille I & II