Glycoside Hydrolase Family 156

Activities in Familyexo-α-sialidase (EC 3.2.1.18)
Mechanism inverting
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp
Catalytic Proton DonorHis
NoteCreated after Chuzel et al. (2018) J. Biol. Chem. (PMID=30249617) who have identified and characterized the founding member of family GH156 via a functional metagenomic screen of DNA from a thermal spring.
Statistics GenBank accession (56); Uniprot accession (1); PDB accession (5); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3D
 exosialidase 3.2.1.18 pubmed
uncultured bacterium pG7 AYA93387.1 A0A5S8WFA6 6RZD[A,B]
6S00[A,B]
6S04[A,B]
6S0E[A,B]
6S0F[A,B]
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