Activities in Family	Exo-α-sialidase (EC 3.2.1.18);
Mechanism	Inverting e
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Asp
Catalytic Proton Donor	His
Note	Created after Chuzel et al. (2018) J. Biol. Chem. (PMID=30249617) who have identified and characterized the founding member of family GH156 via a functional metagenomic screen of DNA from a thermal spring.
External resources	CAZypedia;
Statistics	GenBank accession (67); Uniprot accession (1); PDB accession (5); 3D entries (1); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D
B7X34_04165 (fragment)		Acidobacteriia bacterium 12-62-4	OYW10819.1
HG15A2_26190		Adhaeretor mobilis HG15A2	QDS99297.1
HG15A2_26230		Adhaeretor mobilis HG15A2	QDS99301.1
HG15A2_21450		Adhaeretor mobilis HG15A2	QDS98859.1
HG15A2_26160		Adhaeretor mobilis HG15A2	QDS99294.1
AI2BBH_08410		Alistipes indistinctus 2BBH45	BCG53795.1
NQ495_07900		Alistipes indistinctus YIT 12060	UWN58649.1
COW34_09095		Armatimonadetes bacterium CG17_big_fil_post_rev_8_21_14_2_50_66_6	PIW13520.1
COZ05_14480 (fragment)		Armatimonadetes bacterium CG_4_10_14_3_um_filter_59_10	PIY42111.1
M4951_08445		Blastopirellula sp. J2-11	UUO08331.1
F183_07080		Bryobacterales bacterium F-183	BCS36836.1
F183_A07120		Bryobacterales bacterium F-183	BDC48396.1
UZ16_OP3001001684 (Xynz_1)		Candidatus Hinthialibacteria bacterium OLB16	KXK35835.1
DF168_00379		Candidatus Moanabacter tarae TARA_B100001123	AWT59198.1
DF168_00743		Candidatus Moanabacter tarae TARA_B100001123	AWT59553.1
DF168_00693 (fragment)		Candidatus Moanabacter tarae TARA_B100001123	AWT59503.1
DF168_00832		Candidatus Moanabacter tarae TARA_B100001123	AWT59639.1
CVU38_18320		Chloroflexi bacterium HGW-Chloroflexi-1	PKO20768.1
DBY04_02790		Clostridiales bacterium	PWL98936.1
DBX47_00500		Clostridiales bacterium	PWM47548.1
LL033_16265		Clostridium estertheticum CF002	WAG54186.1
LL065_09540		Clostridium estertheticum CF016	WAG42893.1
RBU49_00610		Clostridium sp. MB40-C1	WMJ80778.1
SH580_03170		Coraliomargarita sp. J2-16	WPJ96704.1
SH580_03280		Coraliomargarita sp. J2-16	WPJ96726.1
GmarT_48210 (fragment)		Gimesia maris DSM 8797	QEG18926.1
F1729_05600		Gimesia maris DSM 8797	QGQ28171.1
K0B96_12635		Horticoccus luteus KSB-15	QYM78151.1
SAMN04515669_3133		Jiangella sp. DSM 45060	SDT21651.1
L21SP4_00372		Kiritimatiella glycovorans L21-Fru-AB	AKJ63652.1
A2283_17630		Lentisphaerae bacterium RIFOXYA12_FULL_48_11	OGV62276.1
DBX90_12595		Lentisphaerota bacterium	PWM75538.1
SMSP2_02518		Limihaloglobus sulfuriphilus SM-Chi-D1	AQQ72137.1
OPIT5_23810		Opitutaceae bacterium TAV5	AHF92766.1
OPIT5_16845		Opitutaceae bacterium TAV5	AHF91630.1
OPIT5_14045		Opitutaceae bacterium TAV5	AHF91164.1
B9S28_02745		Opitutae bacterium Tous-C10FEB	PAW86540.1
SAMN05444173_3022		Opitutus sp. GAS368	SDS48178.1
DQG23_19160		Paenibacillus contaminans CKOBP-6	RAV19586.1
H7F31_32050		Paenibacillus sp. PAMC21692	QNK57070.1
IRI77_35630		Paludibaculum fermentans P105	QOY88011.1
NQ564_16735		Parabacteroides johnsonii DSM 18315	UWP42532.1
NQ542_15490		Parabacteroides merdae ATCC 43184	UWP46118.1
K6V24_12090		Parabacteroides merdae BFG-280	UBD60225.1
INE87_02366		Parabacteroides merdae CL06T03C08	QUT49878.1
QG516_02840		Pedobacter gandavensis WB7	WGQ10591.1
PEIBARAKI_4714 (fragment)		Petrimonas sp. IBARAKI	BBD44721.1
PBC10988_36770		Planctomycetales bacterium 10988	QGJ71964.1
CA11_47170 (fragment)		Planctomycetes bacterium CA11	QDU16880.1
Mal33_39790		Planctomycetes bacterium Mal33	QDV57963.1
Mal35_46410 (fragment)		Planctomycetes bacterium Mal35	QDT81162.1
MalM14_29720		Planctomycetes bacterium MalM14	QDT85304.1
Pan258_59750		Planctomycetes bacterium Pan258	QDT51878.1
Pla110_40870		Polystyrenella longa Pla110	QDU82332.1
G5S37_09955		Roseimicrobium sp. ORNL1	QIF01836.1
Poly24_42530		Rosistilla carotiformis Poly24	QDV70529.1
EC9_40330		Rosistilla ulvae EC9	QDS89832.1
QYC40_04240		Sphingobacterium sp. BN32	WKK59441.1
GFH32_12200		Sphingobacterium sp. dk4302	QGA27036.1
Mal52_61130		Symmachiella dynata Mal52	QDU47578.1
Mal48_21640		Thalassoglobus polymorphus Mal48	QDT32916.1
GT409_10390		Tichowtungia aerotolerans S-5007	QHI69841.1
GT409_10385		Tichowtungia aerotolerans S-5007	QHI69840.1
exosialidase	3.2.1.18	uncultured bacterium pG7	AYA93387.1	A0A5S8WFA6	6RZD[A,B] 6S00[A,B] 6S04[A,B] 6S0E[A,B] 6S0F[A,B]
ORF		uncultured Planctomycetales bacterium HF0500_40D21	ADI19485.1
ORF		uncultured Planctomycetales bacterium HF0500_40D21	ADI23018.1
C8D82_1282		Victivallis vadensis DSM 14823	PVY38102.1
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