Glycoside Hydrolase Family 13

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); amino acid transporter; [retaining] sucrose 6(F)-phosphate phosphorylase (EC 2.4.1.329); [retaining] glucosylglycerol phosphorylase (EC 2.4.1.359); ; Glucosylglycerate phosphorylase (EC 2.4.1.352); [retaining] sucrose α-glucosidase (EC 3.2.1.48); oligosaccharide α-4-glucosyltransferase (EC 2.4.1.161); [retaining] α-amylase (EC 3.2.1.1)
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (117346); Uniprot accession (7841); PDB accession (587); 3D entries (139); cryst (2)
All (112273) Archaea (638) Bacteria (106893) Eukaryota (4608) Viruses (3) unclassified (131) Structure (139 - 2 cryst) Characterized (826)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D Subf
 BVU17_11455   Haloarcula taiwanensis AUG48107.1     16
 BVU17_13580   Haloarcula taiwanensis AUG48503.1    
 BVU17_04730   Haloarcula taiwanensis AUG46856.1     31
 BVU17_04725   Haloarcula taiwanensis AUG46855.1     31
 HARCEL1_05000   Haloarculaceae archaeon HArcel1 AWB27109.1    
 HSBGL_2676 (Amya9) (fragment)   Haloarculaceae archaeon HSR-Bgl QSG13076.1     43
 HSBGL_2045 (Amya7)   Haloarculaceae archaeon HSR-Bgl QSG12454.1     31
 HSBGL_2255 (Amya8)   Haloarculaceae archaeon HSR-Bgl QSG12662.1     31
 HSBGL_1505 (Amya5) (fragment)   Haloarculaceae archaeon HSR-Bgl QSG11922.1     16
 HSBGL_1138 (Amya2)   Haloarculaceae archaeon HSR-Bgl QSG11562.1    
 HSBGL_1054 (AmyA)   Haloarculaceae archaeon HSR-Bgl QSG11481.1    
 HSBGL_1187 (Amya3)   Haloarculaceae archaeon HSR-Bgl QSG11611.1     4
 HSBGL_1492 (Amya4)   Haloarculaceae archaeon HSR-Bgl QSG11909.1    
 HSBGL_1647 (Amya6)   Haloarculaceae archaeon HSR-Bgl QSG12063.1     31
 HSBGL_0716   Haloarculaceae archaeon HSR-Bgl QSG11150.1     43
 HSEST_2720 (Amya14)   Haloarculaceae archaeon HSR-Est QSG16229.1     16
 HSEST_2231 (fragment)   Haloarculaceae archaeon HSR-Est QSG15745.1     43
 HSEST_1643 (Amya9)   Haloarculaceae archaeon HSR-Est QSG15168.1    
 HSEST_1156 (Amya5)   Haloarculaceae archaeon HSR-Est QSG14689.1    
 HSEST_2722 (Amya16)   Haloarculaceae archaeon HSR-Est QSG16231.1     16
 HSEST_1409 (Amya6)   Haloarculaceae archaeon HSR-Est QSG14940.1     43
 HSEST_1934 (Amya10)   Haloarculaceae archaeon HSR-Est QSG15453.1    
 HSEST_0298 (AmyA)   Haloarculaceae archaeon HSR-Est QSG13848.1    
 HSEST_2142 (Amya11)   Haloarculaceae archaeon HSR-Est QSG15657.1    
 HSEST_1628 (Amya8)   Haloarculaceae archaeon HSR-Est QSG15154.1     31
 HSEST_2719 (Amya13)   Haloarculaceae archaeon HSR-Est QSG16228.1     4
 HSEST_2721 (Amya15)   Haloarculaceae archaeon HSR-Est QSG16230.1     31
 HSEST_0875 (Amya3)   Haloarculaceae archaeon HSR-Est QSG14417.1    
 HSEST_1576 (Amya7)   Haloarculaceae archaeon HSR-Est QSG15105.1    
 HSEST_0555 (Amya2) (fragment)   Haloarculaceae archaeon HSR-Est QSG14102.1     43
 HSEST_0896 (Amya4)   Haloarculaceae archaeon HSR-Est QSG14437.1     31
 HSEST_2283 (Amya12)   Haloarculaceae archaeon HSR-Est QSG15795.1    
 HSR121_1150 (Amya3) (fragment)   Haloarculaceae archaeon HSR12-1 QSG05497.1     16
 HSR121_2464 (fragment)   Haloarculaceae archaeon HSR12-1 QSG06785.1     43
 HSR121_2252 (Amya8)   Haloarculaceae archaeon HSR12-1 QSG06581.1     31
 HSR121_2253 (Amya9)   Haloarculaceae archaeon HSR12-1 QSG06582.1     31
 HSR121_2197 (Amya7)   Haloarculaceae archaeon HSR12-1 QSG06527.1     31
 HSR121_1224 (Amya4)   Haloarculaceae archaeon HSR12-1 QSG05570.1     4
 HSR121_1134 (Amya2)   Haloarculaceae archaeon HSR12-1 QSG05481.1    
 HSR121_1527 (Amya5)   Haloarculaceae archaeon HSR12-1 QSG05869.1    
 HSR121_0731 (AmyA) (fragment)   Haloarculaceae archaeon HSR12-1 QSG05085.1     43
 HSR121_1674 (Amya6)   Haloarculaceae archaeon HSR12-1 QSG06011.1    
 HSR122_0387 (AmyA) (fragment)   Haloarculaceae archaeon HSR12-2 QSG07798.1     43
 HSR122_1263 (Amya5)   Haloarculaceae archaeon HSR12-2 QSG08661.1     4
 HSR122_1595 (Amya6)   Haloarculaceae archaeon HSR12-2 QSG08986.1    
 HSR122_2063 (Amya9)   Haloarculaceae archaeon HSR12-2 QSG09447.1    
 HSR122_1212 (Amya4)   Haloarculaceae archaeon HSR12-2 QSG08610.1    
 HSR122_1825 (Amya8)   Haloarculaceae archaeon HSR12-2 QSG09211.1     31
 HSR122_1608 (Amya7) (fragment)   Haloarculaceae archaeon HSR12-2 QSG08999.1     16
 HSR122_0805 (Amya2)   Haloarculaceae archaeon HSR12-2 QSG08209.1     31
 HSR122_1017 (Amya3)   Haloarculaceae archaeon HSR12-2 QSG08419.1     31
 HSR122_2378 (fragment)   Haloarculaceae archaeon HSR12-2 QSG09755.1     43
 AArcS_0416 (Amya2)   Halobacteriaceae archaeon AArc-S QSG01645.1    
 AArcS_0863 (Amya4)   Halobacteriaceae archaeon AArc-S QSG02086.1    
 AArcS_1062   Halobacteriaceae archaeon AArc-S QSG02283.1     43
 AArcS_2696   Halobacteriaceae archaeon AArc-S QSG03892.1     43
 AArcS_2697 (Amya9)   Halobacteriaceae archaeon AArc-S QSG03893.1    
 AArcS_1404 (Amya6)   Halobacteriaceae archaeon AArc-S QSG02619.1     31
 AArcS_3130 (Amya10)   Halobacteriaceae archaeon AArc-S QSG04317.1    
 AArcS_1405 (Amya7)   Halobacteriaceae archaeon AArc-S QSG02620.1     31
 AArcS_0501 (Amya3)   Halobacteriaceae archaeon AArc-S QSG01730.1    
 AArcS_0289 (AmyA)   Halobacteriaceae archaeon AArc-S QSG01523.1    
 AArcS_1411 (Amya8)   Halobacteriaceae archaeon AArc-S QSG02626.1    
 AArcS_1202 (Amya5)   Halobacteriaceae archaeon AArc-S QSG02420.1     31
 DV707_09090   Halobellus limi CGMCC 1.10331 QCC47800.1    
 DV707_13520   Halobellus limi CGMCC 1.10331 QCC48595.1     31
 DV707_12370   Halobellus limi CGMCC 1.10331 QCC48393.1     31
 DV707_08085   Halobellus limi CGMCC 1.10331 QCC48907.1     31
 DV707_07410   Halobellus limi CGMCC 1.10331 QCC47500.1    
 CHINAEXTREME_10100   Halobiforma lacisalsi AJ5 APW98117.1    
 CHINAEXTREME_12360   Halobiforma lacisalsi AJ5 APW98517.1     31
 HUG10_17745   Halobonum sp. Gai3-2 QLG29261.1     31
 HUG10_17750   Halobonum sp. Gai3-2 QLG29262.1     16
 HUG12_18430   Halobonum sp. NJ-3-1 QLG63596.1     31
 HUG12_18425   Halobonum sp. NJ-3-1 QLG63595.1     16
 G3A49_02875   Haloferax alexandrinus wsp1 QIB77145.1    
 G3A49_11660   Haloferax alexandrinus wsp1 QIB80089.1    
 ABY42_09415   Haloferax gibbonsii ARA6 AKU07947.1     31
 ABY42_02600   Haloferax gibbonsii ARA6 AKU06683.1    
 ABY42_09420   Haloferax gibbonsii ARA6 AKU07948.1     31
 ABY42_08360   Haloferax gibbonsii ARA6 AKU07761.1    
 HfgLR_02625   Haloferax gibbonsii LR2-5 QOS10678.1    
 HfgLR_08695   Haloferax gibbonsii LR2-5 QOS11880.1    
 α-cyclomaltodextrin glucanotransferase (Cgt) 2.4.1.19 Haloferax mediterranei CAI46245.1 Q53I75   2
 BM92_03985   Haloferax mediterranei ATCC 33500 AHZ21871.1     31
 BM92_06595   Haloferax mediterranei ATCC 33500 AHZ22338.1    
 BM92_00090   Haloferax mediterranei ATCC 33500 AHZ21153.1    
 BM92_06580   Haloferax mediterranei ATCC 33500 AHZ22336.1     2
 HFX_0535 (Amyp1)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK18262.1
QCQ74785.1
    2
 HFX_0533 (Amy1)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK18260.1
QCQ74783.1
   
 HFX_1044 (Amy3)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK18760.1
QCQ75255.1
    31
 HFX_1802 (Amy4)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK19506.1
AFK19506.2
QCQ76659.1
   
 HVO_0567   Haloferax volcanii DS2 ADE03517.1 D4GSG2  
 HVO_1710   Haloferax volcanii DS2 ADE04704.1 D4H055  
 Hbor_26440   Halogeometricum borinquense DSM 11551 ADQ68196.1 E4NT99  
 GL213_13105   Halogeometricum borinquense wsp3 QIQ77384.1    
 G3I44_02340   Halogeometricum borinquense wsp4 QIB73220.1    
 Hmuk_0209   Halomicrobium mukohataei DSM 12286 ACV46346.1 C7NWY1   20
 Hmuk_2260   Halomicrobium mukohataei DSM 12286 ACV48372.1 C7NXD8   31
 Hmuk_0052   Halomicrobium mukohataei DSM 12286 ACV46203.1 C7NVT8   31
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