Glycoside Hydrolase Family 13 / Subf 7

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (143); Uniprot accession (28); PDB accession (4); 3D entries (2); cryst (0)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase (AmyA;PF0477) 3.2.1.1 Pyrococcus furiosus DSM 3638 AAL80601.1
AAB67705.1
AAC45663.1
NP_578206.1
O08452
Q8U3I9
  7
 α-amylase (AmyA) 3.2.1.1 Pyrococcus woesei AAD54338.1
AAF44693.1
ACH26211.1
Q7LYT7
Q9P9L0
1MWO[A]
1MXD[A]
1MXG[A]
7
 α-amylase (Amy) 3.2.1.1 Thermococcus hydrothermalis AL662 AAC97877.1
AAC97878.1
ACH26213.1
O93647
O93648
  7
 α-amylase (ApkA;TK1884) 3.2.1.1 Thermococcus kodakarensis KOD1 BAA21130.1
ACH26210.1
BAD86073.1
CAT70635.1
O33476
Q5JER7
  7
 α-amylase (TO_Amyl;TON_1660) 3.2.1.1 Thermococcus onnurineus NA1 ABA26948.1
ACJ17150.1
B6YUG5   7
 α-amylase (BD5031) 3.2.1.1 Thermococcus sp. AEPII 1a AAM48113.1
ACH26099.1
Q8NKR4   7
 α-amylase (BD5064) 3.2.1.1 Thermococcus sp. GU5L5 AAM48112.1
ACH26098.1
Q8NKR5   7
 α-amylase (THJA) 3.2.1.1 Thermococcus sp. HJ21 ABU98335.1 B4X9V8   7
 α-amylase 3.2.1.1 Thermococcus sp. Rt3 AAB87860.1
ACH26212.1
O50200   7
 α-amylase (Amy) 3.2.1.1 Thermococcus thioreducens AAT11125.1 Q66SB4   7
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase (BD5063) 3.2.1.1 uncultured organism AAM48114.1
ACH26097.1
Q8JZK3   7
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