Glycoside Hydrolase Family 13 / Subf 5

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (2577); Uniprot accession (238); PDB accession (24); 3D entries (8); cryst (0)
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Bacteria
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 I872_03470   Streptococcus cristatus AS 1.3089 AGK70794.1     5
 SDSE167_0599 (AmyS)   Streptococcus dysgalactiae subsp. equisimilis 167 BAN92991.1     5
 SDSE_0576 (AmyS)   Streptococcus dysgalactiae subsp. equisimilis AC-2713 CCI62074.1     5
 SDE12394_02755   Streptococcus dysgalactiae subsp. equisimilis ATCC 12394 ADX24083.1     5
 SDEG_0546 (AmyS)   Streptococcus dysgalactiae subsp. equisimilis GGS_124 BAH81048.1 C5WF83   5
 GGS_0522 (AmyS)   Streptococcus dysgalactiae subsp. equisimilis RE378 BAM60678.1     5
 SEQ_1595   Streptococcus equi subsp. equi 4047 CAW94579.1 C0M9U2   5
 SE071780_01621   Streptococcus equi subsp. equi ATCC 39506 ASB97210.1     5
 SeseC_01821 (AmyA)   Streptococcus equi subsp. zooepidemicus ATCC 35246 AEJ25702.1     5
 Q426_02075   Streptococcus equi subsp. zooepidemicus CY AIA67285.1     5
 Sez_1409 (AmyS)   Streptococcus equi subsp. zooepidemicus MGCS10565 ACG62745.1 B4U428   5
 α-amylase II (Amy II) 3.2.1.1 Streptococcus equinus 148 BAA24178.1 O50583   5
 A6J79_00180   Streptococcus equinus FDAARGOS_251 ARC32987.1     5
 α-amylase 3.2.1.1 Streptococcus equinus JB1 AAA97431.1 Q53786   5
 AU077_04860   Streptococcus gallolyticus ICDDRB-NRC-S1 ALT80912.1     5
 SGGB_1033 (AmyS)   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143 BAK27902.1     5
 SGGBAA2069_c10200 (Amya1)   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069 CBZ48192.1     5
 BTR42_05520   Streptococcus gallolyticus subsp. gallolyticus DSM 16831 AQP42088.1     5
 GALLO_1043   Streptococcus gallolyticus UCN34 CBI13535.1 D3HDC5   5
 A6J85_09280   Streptococcus gordonii FDAARGOS_257 ARC47546.1     5
 CO687_08295   Streptococcus gordonii FDAARGOS_371 ATF65454.1     5
 WH25_06125   Streptococcus gordonii IE35 AOS71471.1     5
 RN86_08710   Streptococcus gordonii KCOM 1506 (= ChDC B679) ALD72483.1     5
 SGO_1075   Streptococcus gordonii str. Challis substr. CH1 ABV10115.1     5
 AU079_04060   Streptococcus infantarius ICDDRB-NRC-S5 ALT82526.1     5
 Sinf_0846   Streptococcus infantarius subsp. infantarius CJ18 AEZ62184.1     5
 SIR_0857 (AmY)   Streptococcus intermedius B196 AGU76222.1     5
 SII_0874 (AmY)   Streptococcus intermedius C270 AGU78052.1     5
 A6J72_01145   Streptococcus intermedius FDAARGOS_233 ARC25952.1     5
 SCIM_0786 (AmY)   Streptococcus intermedius JTH08 BAM23440.1     5
 RN88_04105   Streptococcus intermedius KCOM 1545 ALF27712.1     5
 SITYG_09110 (AmY)   Streptococcus intermedius TYG1620 BAW16894.1     5
 KE3_0908   Streptococcus lutetiensis 033 AGS05403.1     5
 SMA_0972 (AmyA)   Streptococcus macedonicus ACA-DC 198 CCF02263.1     5
 SAMEA4412692_00891   Streptococcus merionis NCTC13788 SNU88089.1     5
 smi_0750   Streptococcus mitis B6 CBJ21997.1 D3H805   5
 RN80_08005   Streptococcus mitis KCOM 1350 (= ChDC B183) ALD68383.1     5
 AXK38_03525   Streptococcus mitis SVGS_061 AMH88378.1     5
 SMUGS5_07160   Streptococcus mutans GS-5 AFM81927.1     5
 RO10_06420   Streptococcus mutans KCOM 1054 (= ChDC YM3) ARS62847.1     5
 SMULJ23_0536 (AmyA)   Streptococcus mutans LJ23 BAL68870.1     5
 α-amylase (intracellular) (Amy) 3.2.1.1 Streptococcus mutans LT11 AAC35010.1 O68875   5
 APQ13_00635   Streptococcus mutans NG8 AMF84980.1     5
 SmuNN2025_0522 (AmyA)   Streptococcus mutans NN2025 BAH87548.1 C6SPA6   5
 α-amylase (AmyA;SMU.1590) 3.2.1.1 Streptococcus mutans UA159 AAN59233.1
NP_721927.1
    5
 SMUFR_1380   Streptococcus mutans UA159-FR AJD55851.1     5
 CO686_03040   Streptococcus oralis FDAARGOS_367 ATF56454.1     5
 BWR56_1224   Streptococcus oralis S.MIT/ORALIS-351 AQA07782.1     5
 STO1_006610 (AmY)   Streptococcus oralis subsp. tigurinus osk_001 BBA08265.1     5
 SOR_0748   Streptococcus oralis Uo5 CBZ00410.1     5
 A0O21_02485   Streptococcus pantholopis TA 26 AND78965.1     5
 HMPREF0833_10727 (AmyA)   Streptococcus parasanguinis ATCC 15912 AEH55758.1     5
 Spaf_1294 (AmyA)   Streptococcus parasanguinis FW213 AFJ26277.1     5
 STP_0342   Streptococcus parauberis KCTC 11537 AEF24790.1     5
 CTY44_01064   Streptococcus parauberis SpOF 3k ATX06136.1     5
 SPSF3K_00831 (AmyA)   Streptococcus parauberis SPOF3K AUT05557.1     5
 SGPB_0905 (AmyS)   Streptococcus pasteurianus ATCC 43144 BAK29982.1     5
 C0J00_02735   Streptococcus pluranimalium TH11417 AUW96116.1     5
 Sequence 3535 from patent US 6699703   Streptococcus pneumoniae AAT16165.1
ABI03496.1
ABI08537.1
ABJ32053.1
ABJ49666.1
ABL17409.1
ACC20077.1
ACK13955.1
ACW44674.1
    5
 BUM80_04220   Streptococcus pneumoniae 11A AUC45620.1     5
 CWI64_02385   Streptococcus pneumoniae 19F AUB32589.1     5
 SP670_0915   Streptococcus pneumoniae 670-6B ADM90980.1 E0TMD1   5
 SP70585_1420   Streptococcus pneumoniae 70585 ACO18012.1 C1C7Y2   5
 T308_04120   Streptococcus pneumoniae A026 AGZ47589.1     5
 A66_01222   Streptococcus pneumoniae A66 CRI61933.1     5
 SPAP_1412   Streptococcus pneumoniae AP200 ADM84998.1 E0SUR4   5
 SPN23F13470   Streptococcus pneumoniae ATCC 700669 CAR69147.1 B8ZKN0   5
 SPCG_1371 (Amy)   Streptococcus pneumoniae CGSP14 ACB90623.1 B2IQJ9   5
 SPND122_01324   Streptococcus pneumoniae D122 AOG56199.1     5
 SPND141_01327   Streptococcus pneumoniae D141 AOG58344.1     5
 SPD_1215   Streptococcus pneumoniae D39 ABJ54813.1 Q04JW6   5
 SPG_1322   Streptococcus pneumoniae G54 ACF54809.1 B5E5N9   5
 HMPREF1038_01370 (AmY)   Streptococcus pneumoniae gamPNI0373 AFS43402.1     5
 SPNHU15_01428   Streptococcus pneumoniae Hu15 ARD37202.1     5
 SPNHU17_01434   Streptococcus pneumoniae Hu17 ARD35004.1     5
 SPH_1513   Streptococcus pneumoniae Hungary19A-6 ACA37514.1 B1ICI2   5
 INV104_11770   Streptococcus pneumoniae INV104 CBW36858.1 E1XRW0   5
 SPNINV200_12270   Streptococcus pneumoniae INV200 CBW34860.1 E1XKH3   5
 SPJ_1281   Streptococcus pneumoniae JJA ACO18360.1 C1CEX0   5
 KK0381_08500   Streptococcus pneumoniae KK0381 BAX31034.1     5
 KK0981_33540   Streptococcus pneumoniae KK0981 BAW84844.1     5
 KK1157_09010   Streptococcus pneumoniae KK1157 BAX33262.1     5
 MDRSPN_00704 (AmY)   Streptococcus pneumoniae MDRSPN001 BBA58910.1     5
 ERS445053_01390 (AmyS)   Streptococcus pneumoniae NCTC7465 COT20290.1     5
 SpnNT_00884 (AmyS)   Streptococcus pneumoniae NT_110_58 AJD71825.1     5
 SPNOXC_12150   Streptococcus pneumoniae OXC141 CBW32869.1 E1XH16   5
 SPP_1401   Streptococcus pneumoniae P1031 ACO20564.1 C1CL90   5
 AMY   Streptococcus pneumoniae R6 AAL00043.1
NP_358832.1
Q8DPC8   5
 BMJ42_01357   Streptococcus pneumoniae SP49 APJ30656.1     5
 BOC71_00822 (AmyS)   Streptococcus pneumoniae SP61 APJ32330.1     5
 BOC72_00822   Streptococcus pneumoniae SP64 APJ34355.1     5
 SPN034156_03010   Streptococcus pneumoniae SPN034156 SNP034156 CCP35970.1     5
 SPN034183_12130   Streptococcus pneumoniae SPN034183 SNP034183 CCP32923.1     5
 SPN994038_12020   Streptococcus pneumoniae SPN994038 SNP994038 CCP30938.1     5
 SPN994039_12030   Streptococcus pneumoniae SPN994039 SNP994039 CCP34897.1     5
 SPNA45_00821   Streptococcus pneumoniae SPNA45 CCM08107.1     5
 MYY_0907   Streptococcus pneumoniae ST556 AFC94568.1     5
 SPT_0892   Streptococcus pneumoniae Taiwan19F-14 ACO22550.1 C1CQX4   5
 HMPREF0837_11165   Streptococcus pneumoniae TCH8431/19A ADI69393.1 D6ZS04   5
 SP1382   Streptococcus pneumoniae TIGR4 AAK75480.1
NP_345840.1
Q97Q49   5
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