Glycoside Hydrolase Family 13 / Subf 41

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (85); Uniprot accession (19);
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 alkaline amylase-pullulanase 3.2.1.1
3.2.1.41
Bacillus sp. KSM-1378 AAS36537.1
AAS36538.1
BAA11332.1
P70983   41
 multidomain α-amylase (EUR_21100) (cell-wall anchored) 3.2.1.1 [Eubacterium] rectale DSM 17629 CBK91127.1 D6DYI9   41
 α-amylase 3.2.1.1 Micrococcus sp. 207 CAA39321.1 Q06812   41
 α-amylase (AmyB) (Amy13A) 3.2.1.1 Roseburia sp. A2-194 CAJ20070.1 Q3LB10   41
 bifunctional amylopullulanase (ApuA;SSU1849) 3.2.1.1
3.2.1.41
Streptococcus suis P1/7 CAR47543.1 C5VVZ9   41
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