Glycoside Hydrolase Family 13 / Subf 34

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (76); Uniprot accession (22); PDB accession (2); 3D entries (1); cryst (0)
All (29) Eukaryota (29) Structure (1)
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 solute carrier family 3 (SLC3A2)   Bos taurus AAX08732.1
AAI02421.1
AAI23691.1
AAX46388.1
Q5EA54   34
 solute carrier family 3 member 2 (Slc3a2)   Bubalus bubalis AIP90167.1     34
 ORF   Callorhinchus milii AFP01274.1     34
 ORF (fragment)   Callorhinchus milii AFP02854.1     34
 4F2 cell-surface antigen heavy chain (4f2hC)   Canis lupus familiaris BAO65809.1     34
 CD98-related protein   Cricetulus griseus AAB97631.1 O55221   34
 ORF   Danio rerio AAH44497.1
AAH63982.1
Q803G1   34
 Unknown (protein for MGC:158423)   Danio rerio AAI28866.1 A1A5Y9   34
 solute carrier (Slc3a2)   Danio rerio AAH53236.1
AAG37838.1
AAI59203.1
NP_571676.1
Q7T2P3
Q9DDS9
  34
 4F2 heavy chain antigen (4f2hc)   Homo sapiens AAA52497.1
AAA35489.1
AAA35536.1
AAA51540.1
AAH01061.1
AAH01061.2
AAH03000.1
AAH03000.2
AAS26022.1
AAS26189.1
ABA66456.1
ACC10874.1
ACJ91468.1
ACR85919.1
ACR85923.1
ACW43720.1
BAA84649.1
BAG65305.1
CAY39141.1
NP_002385.2
NP_002385.3
P08195 2DH2[A]
2DH3[A,B]
34
 ORF   Macaca fascicularis BAE01592.1
BAE87247.1
Q4R5N3   34
 4F2 cell-surface antigen heavy chain isoform b (Slc3a2)   Macaca mulatta AFE67000.1     34
 4F2 cell-surface antigen heavy chain isoform c (Slc3a2)   Macaca mulatta AFE67118.1
AFH28051.1
AFI33834.1
    34
 4F2 cell-surface antigen heavy chain isoform c (Slc3a2)   Macaca mulatta AFJ70224.1     34
 cell surface antigen 4F2 heavy chain   Mus musculus AAB03769.1
AAH65173.1
BAA90555.1
BAC41063.1
BAE33656.1
BAE36291.1
BAE38172.1
BAE38250.1
CAA32490.1
NP_032603.2
P10852
Q60849
Q8BTJ9
  34
 Sequence 3 from patent US 7307145   Mus musculus ABY16135.1
ACJ97625.1
BAE39805.1
P10852   34
 ORF (partial)   Mustela putorius furo AES06878.1     34
 ORF   Oryctolagus cuniculus AAP47190.1 Q7YQK3   34
 unnamed protein product   Pan troglodytes CAY39140.1
BAK63499.1
    34
 CD98 solute carrier family 3 member 2 (SLC3A2)   Petromyzon marinus AAN64301.1 Q8AV90   34
 DKFZp469L1516   Pongo abelii CAH90818.1 Q5RBP2   34
 cell surface antigen 4F2 heavy chain   Rattus norvegicus AAC53560.1
AAH61989.1
ACJ91469.1
BAA33036.1
CAA61509.1
NP_062156.1
Q64304
Q794F9
  34
 4F2 cell-surface antigen heavy chain (4f2)   Salmo salar ACI33885.1 B5X3K4   34
 4F2   Salmo salar ACN11142.1 C0HAS3   34
 solute carrier family 3 member 2   Siniperca chuatsi AKI29975.1     34
 SLC3A2 (fragment)   Sus scrofa ACB46190.1 B2D2K7   34
 ORF   Xenopus laevis AAH42294.1 Q7ZYQ1   34
 ORF   Xenopus laevis AAH42234.1 Q7ZYR3   34
 Unknown (protein for IMAGE:7025754) (fragment)   Xenopus tropicalis AAH81372.1 Q66IF2   34
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