Activities in Family	α-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
	Activities in Sub Family
Mechanism	Retaining
Clan	GH-H
3D Structure Status	( β / α ) 8
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (3659); Uniprot accession (502); PDB accession (40); 3D entries (11); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)	Subf
oligo-α-1,6-glucosidase (MalL)	3.2.1.10	Bacillus cereus ATCC 7064	CAA37583.1	P21332	1UOK[A] 2.00	31
α-1,6-glucosidase (MalL;YvdL;BSU34560)	3.2.1.10	Bacillus subtilis subsp. subtilis str. 168	CAB15461.1 AIY94772.1 AQR83490.1 AQR87705.1 CAB08041.1 NP_391336.1	O06994	4M56[A,B] 2.30 4M8U[A] 1.45 4MAZ[A] 1.60 4MB1[A] 1.40	31
isomaltulose synthase (PalI)	5.4.99.11	Erwinia rhapontici NX-5 / DSM 4484	AAK28735.1 AAY69569.1 ACW35803.1 ADJ56407.2 CAC69266.1 CAC69272.1 CAC69285.1 CAF32986.1 CAF32987.1	D9MPF2 Q9AI64	4HOW[A] 1.70 4HOX[A] 2.00 4HOZ[A] α-D-Glcp 2.00 4HP5[A] α-D-Glcp 2.00 4HPH[A] α-D-Glcp-(1-2)-β-D-Fruf 1.70	31
α-glucosidase (Gsj)	3.2.1.20	Geobacillus sp. HTA-462	BAE48285.1	Q33E90	2ZE0[A] 2.00	31
isomaltulose synthase (PalI)	5.4.99.11	Klebsiella sp. LX3	AAK82938.1 CAF32992.1 CAF32993.1 CBF79192.1	Q8KR84	1M53[A] 2.20	31
oligo-α-1,6-glucosidase (LBA0264)	3.2.1.10	Lactobacillus acidophilus NCFM	AAV42157.1	Q5FMB7	4AIE[A] 2.05	31
α-1,6-glucosidase (Lmo0184)	3.2.1.20	Listeria monocytogenes EGD-e	NP_463715.1 CAC98399.1 CAZ78714.1	Q8YAE6	5DO8[A,B,C] β-D-Glcp 1.80	31
sucrose isomerase (SmuA)	5.4.99.11	Protaminobacter rubrum CBS 547.77	CAF32988.1 AAE36427.1 AAY69568.1 AAY69572.1 ACW35802.1 ACW35805.1 CAF32985.1		3GBD[A] 1.95 3GBE[A] <carb_like_NOJ> 1.70	31
sucrose isomerase / trehalulose synthase (MutB)	5.4.99.11	Pseudomonas mesoacidophila MX-45	ABC33903.1 AAY69574.1 ABT00107.1 ACO05018.1 CAF32995.1	Q2PS28	1ZJA[A,B] 1.60 1ZJB[A,B] 1.80 2PWD[A,B] <carb_like_NOJ> 1.80 2PWE[A,B] α-D-Glcp-(1-2)-β-D-Fruf 2.00 2PWF[A,B,C,D] β-D-Glcp 1.80 2PWG[A,B] <carb_like_CTS> 2.20 2PWH[A,B] 2.00 4GI6[A,B] α-D-Glcp 2.15 4GI8[A,B] 1.95 4GI9[A,B] 2.15 4GIA[A,B] 2.01 4GIN[A] 1.90 4GO8[A,B] 2.15 4GO9[A,B] 2.20 4H2C[A] 1.70 4H7V[A,B] α-D-Glcp 1.80 4H8H[A,B] 2.00 4H8U[A,B] α-D-Glcp-(1-1)-<non_carb> α-D-Glcp-(1-2)-β-D-Fruf 2.00 4H8V[A,B] α-D-Glcp-(1-1)-<non_carb> 1.95 4HA1[A,B] α-D-Glcp α-D-Glcp-(1-1)-<non_carb> 2.20	31
dextran α-1,6-glucosidase (DexB;SmDG)	3.2.1.70	Streptococcus mutans ATCC 25175	BAE79634.1	Q2HWU5	2ZIC[A] 2.20 2ZID[A] α-D-Glcp-(1-6)-α-D-Glcp-(1-6)-α-D-Glcp 2.20	31
dextran α-1,6-glucosidase (DexB;SMU.883)		Streptococcus mutans UA159	AAN58598.1 NP_721292.1	Q99040	4WLC[A] β-D-Glcp-(1-4)-ASP 2.40 4XB3[A] 2.09	31
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