Glycoside Hydrolase Family 13 / Subf 31

Activities in Family	α-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
	Activities in Sub Family
Mechanism	Retaining
Clan	GH-H
3D Structure Status	( β / α ) ₈
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (3659); Uniprot accession (502); PDB accession (40); 3D entries (11); cryst (0)

Summary

All (3417) Archaea (15) Bacteria (3400) unclassified (2) Structure (11) Characterized (34)


Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D	Subf
oligo-α-1,6-glucosidase (BC4015)	3.2.1.10	Bacillus cereus ATCC 14579	AAP10934.1 NP_833733.1	Q819G7		31
oligo-α-1,6-glucosidase (MalL)	3.2.1.10	Bacillus cereus ATCC 7064	CAA37583.1	P21332	1UOK[A]	31
oligo-α-1,6-glucosidase (MalL)	3.2.1.10	Bacillus coagulans ATCC7050	BAA11354.1	Q45101		31
oligo-α-1,6-glucosidase	3.2.1.10	Bacillus sp. F5	BAA00534.1	P29093		31
α-glucosidase	3.2.1.20	Bacillus sp. SAM1606	CAA54266.1 CBF79159.1	Q45517		31
oligosaccharide-producing multifunctional amylase (OPMA)	2.4.1.-	Bacillus sp. ZW2531-1	ACE77085.1	B3VDZ7		31
oligo-α-1,6-glucosidase	3.2.1.10	Bacillus subtilis HB002	AAG23399.1 CBF79210.1	Q9F4G4		31
α-1,6-glucosidase (MalL;YvdL;BSU34560)	3.2.1.10	Bacillus subtilis subsp. subtilis str. 168	CAB15461.1 AIY94772.1 AQR83490.1 AQR87705.1 CAB08041.1 NP_391336.1	O06994	4M56[A,B] 4M8U[A] 4MAZ[A] 4MB1[A]	31
oligo α-glucosidase (AglA)	3.2.1.10	Bifidobacterium adolescentis DSM 20083	AAK27723.1	Q9AF93		31
α-1,6-glucosidase 1 (Agl1; Bbr_1855)	3.2.1.10 3.2.1.20	Bifidobacterium breve UCC2003	ACM89182.1 ABE96517.1	C0JP82		31
α-1,6-glucosidase 2 (Agl2; Bbr_0559)	3.2.1.10 3.2.1.20	Bifidobacterium breve UCC2003	ACM89183.1 ABE95255.1	C0JP83		31
sucrose isomerase (EsI)	5.4.99.11	Enterobacter sp. FMB-1	ACF42098.1	B5ABD8		31
α-glucosidase (PalZ)	3.2.1.20	Erwinia rhapontici DSM 4484	AAK28739.1 CAC69267.1 CAC69279.1 CBF79203.1	Q9AI60		31
oligo-α-glucosidase / palatinase (PalQ)	3.2.1.10 3.2.1.-	Erwinia rhapontici DSM 4484	AAK28737.1 CAC69265.1 CAC69271.1 CBF79205.1	Q9AI62		31
isomaltulose synthase (PalI)	5.4.99.11	Erwinia rhapontici NX-5 / DSM 4484	AAK28735.1 AAY69569.1 ACW35803.1 ADJ56407.2 CAC69266.1 CAC69272.1 CAC69285.1 CAF32986.1 CAF32987.1	D9MPF2 Q9AI64	4HOW[A] 4HOX[A] 4HOZ[A] 4HP5[A] 4HPH[A]	31
isomaltulose synthase	5.4.99.11	Erwinia rhapontici WAC2928	AAP57084.1 ACR90553.1	Q6XNK5		31
α-glucosidase (Gsj)	3.2.1.20	Geobacillus sp. HTA-462	BAE48285.1	Q33E90	2ZE0[A]	31
α-glucosidase / exo-α-1,4-glucosidase	3.2.1.20	Geobacillus stearothermophilus ATCC12016	BAA12704.1 CBF79155.1	P94451		31
isomaltulose synthase (PalI)	5.4.99.11	Klebsiella sp. LX3	AAK82938.1 CAF32992.1 CAF32993.1 CBF79192.1	Q8KR84	1M53[A]	31
sucrose isomerase (PalI)	5.4.99.11	Klebsiella sp. NK33-98-8	AAM96902.1	Q4L2Q1		31
oligo-α-1,6-glucosidase (LBA0264)	3.2.1.10	Lactobacillus acidophilus NCFM	AAV42157.1	Q5FMB7	4AIE[A]	31
α-1,6-glucosidase (Lmo0184)	3.2.1.20	Listeria monocytogenes EGD-e	NP_463715.1 CAC98399.1 CAZ78714.1	Q8YAE6	5DO8[A,B,C]	31
isomaltulose synthase	5.4.99.11	Pantoea dispersa UQ68J	AAP57083.1	Q6XNK6		31
oligo-α-1,6-glucosidase (MalL)	3.2.1.10	Parageobacillus thermoglucosidans KP1006	BAA01368.1 CBF79249.1	P29094		31
sucrose isomerase (PCSI;SIase)	5.4.99.11	Pectobacterium carotovorum KKH 3-1	AGT14432.1			31
α-glucosidase (Agl)	3.2.1.20	Pediococcus pentosaceus PPE1.0	AAA25570.1 CAA83671.1 CBF79225.1	P43473		31
sucrose isomerase (SmuA)	5.4.99.11	Protaminobacter rubrum CBS 547.77	CAF32988.1 AAE36427.1 AAY69568.1 AAY69572.1 ACW35802.1 ACW35805.1 CAF32985.1		3GBD[A] 3GBE[A]	31
sucrose isomerase / trehalulose synthase (MutB)	5.4.99.11	Pseudomonas mesoacidophila MX-45	ABC33903.1 AAY69574.1 ABT00107.1 ACO05018.1 CAF32995.1	Q2PS28	1ZJA[A,B] 1ZJB[A,B] 2PWD[A,B] 2PWE[A,B] 2PWF[A,B,C,D] 2PWG[A,B] 2PWH[A,B] 4GI6[A,B] 4GI8[A,B] 4GI9[A,B] 4GIA[A,B] 4GIN[A] 4GO8[A,B] 4GO9[A,B] 4H2C[A] 4H7V[A,B] 4H8H[A,B] 4H8U[A,B] 4H8V[A,B] 4HA1[A,B]	31
palatinase / trehalulose hydrolase (MutA)	3.2.1.10 3.2.1.-	Pseudomonas mesoacidophila MX-45	CAA02858.1 AAE36430.1 AAY69575.1 ACO05017.1 ACO05017.2	C1K2X6		31
isomaltulose synthase	5.4.99.11	Raoultella planticola	AAP57085.1 CBF79174.1	Q6XKX6		31
sucrose isomerase	5.4.99.11	Serratia plymuthica ATCC 15928	CAF32996.1 CAF32990.1			31
α-1,4-glucosidase (MalA)	3.2.1.20	Staphylococcus xylosus	CAA55409.1	Q60015		31
dextran α-1,6-glucosidase (DexB;SmDG)	3.2.1.70	Streptococcus mutans ATCC 25175	BAE79634.1	Q2HWU5	2ZIC[A] 2ZID[A]	31
dextran α-1,6-glucosidase (DexB)	3.2.1.70	Streptococcus mutans INGBRITT	AAA26939.1	Q99040		31
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