Glycoside Hydrolase Family 13 / Subf 2

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (286); Uniprot accession (77); PDB accession (54); 3D entries (9); cryst (0)
All (246) Archaea (29) Bacteria (217) Structure (9) Characterized (51)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-cyclomaltodextrin glucanotransferase (Cgt) 2.4.1.19 Haloferax mediterranei CAI46245.1 Q53I75   2
 β-cyclodextrin glucanotransferase (PfCgt;PF0478;PF0478*) 2.4.1.19 Pyrococcus furiosus DSM 3638 ABA33720.1
AAL80602.1
ABA30024.1
ABA30025.1
NP_578207.1
Q3HUR2
Q8U3I8
  2
 β-cyclodextrin glucanotransferase (Cgt;TK-cgt;TK2172) 2.4.1.19 Thermococcus kodakarensis KOD1 BAB78538.1
BAD86361.1
CAT70763.1
Q8X268   2
 α-cyclodextrin glucanotransferase (CgtA) 2.4.1.19 Thermococcus sp. B1001 BAA88217.1
BAB18101.1
CAZ78889.1
Q9UWN2   2
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 acarviosyltransferase (AcbD; ACPL_3684) 2.4.1.- Actinoplanes sp. SE50/110 CAC02971.1
AAE37556.1
AEV84579.1
CAJ81031.1
SLM00379.1
Q9K5L5   2
 β-cyclodextrin glycosyltransferase (CGTase) 2.4.1.19 Anaerobranca gottschalkii CAH61550.1 Q5ZEQ7   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus circulans 251 CAA55023.1 P43379 1CDG[A]
1CGV[A]
1CGW[A]
1CGX[A]
1CGY[A]
1CXE[A]
1CXF[A]
1CXH[A]
1CXI[A]
1CXK[A]
1CXL[A]
1D3C[A]
1DTU[A]
1EO5[A]
1EO7[A]
1KCK[A]
1KCL[A]
1OT1[A]
1OT2[A]
1PEZ[A]
1PJ9[A]
1TCM[A,B]
2CXG[A]
2DIJ[A]
2
 β-cyclodextrin glucanotransferase (CGTase) 2.4.1.19 Bacillus circulans 8 CAA48401.1 P30920 1CGT[A]
1CGU[A]
3CGT[A]
4CGT[A]
5CGT[A]
6CGT[A]
7CGT[A]
8CGT[A]
9CGT[A]
2
 a/β-cyclodextrin glycosyltransferase 2.4.1.19 Bacillus circulans DF 9R ACF42340.2
ACF42340.1
C4MH58   2
 α-amylase 2.4.1.19
3.2.1.1
Bacillus circulans F-2 AAA22229.1 P08137   2
 β-cyclodextrin glycosyltransferase 2.4.1.19 Bacillus circulans STB01 AIS84204.1     2
 g-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus clarkii 7364 BAH14968.1
ABC06412.1
BAB91217.1
BAB91217.2
CAD87625.1
B9A1J6
Q8L3E0
4JCM[A] 2
 g-cyclodextrin glucanotransferase 2.4.1.19 Bacillus firmus DSM 5850 / 290-3 CAA01436.1     2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus halodurans US193 CAL25733.1 Q0JW31   2
 a/β-cyclodextrin glucanotransferase (CgtA) 2.4.1.19 Bacillus licheniformis CAA33763.1 P14014   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus ohbensis C-1400 BAA14289.2
I39805
P27036   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 1-1   P31746   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 1011 AAA22308.1 P05618 1D7F[A]
1DED[A]
1I75[A]
1PAM[A]
1UKQ[A,B]
1UKS[A,B]
1UKT[A,B]
1V3J[A,B]
1V3K[A,B]
1V3L[A,B]
1V3M[A,B]
2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 17-1 AAA22310.1 P30921   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 20RF AEL33336.1     2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 38-2 AAA22309.1
BAA00077.1
P09121   2
 cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 6.3.3 CAA46901.1 P31747   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. 8SB AEL33337.1     2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. A2-5A BAA31539.1 O82984   2
 β-cyclomaltodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. B1018 AAA22239.1
BAA14140.1
P17692   2
 g-cyclomaltdextrin glucanotransferase (CgtS) 2.4.1.19 Bacillus sp. G-825-6 BAE87038.1 Q25CB6   2
 β-cyclodextrin glucanotransferase 2.4.1.19 Bacillus sp. G1-2004 AAV38118.2 Q5U9V9   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. I-5 AAR32682.1 Q6S3E3   2
 β-cyclodextrin glucanotransferase 2.4.1.19 Bacillus sp. KC201 BAA02380.1
2009322A
Q59239   2
 β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Bacillus sp. NR5 UPM ADY17981.1     2
 β-cyclodextrin glucanotransferase 2.4.1.19 Bacillus sp. TS1-1 AAV38117.1 Q5U9W0   2
 β-cyclodextrin glycosyltransferase (Cgt) 2.4.1.19 Brevibacillus brevis CD162 AAB65420.1 O30565   2
 maltogenic α-amylase (BSuA;Novamyl) 3.2.1.133 Geobacillus stearothermophilus C599 ABA38666.1
AAA22233.1
AAY11155.1
ALJ77020.1
CAL60144.1
CAZ67881.1
P19531 1QHO[A]
1QHP[A]
2
 β-cyclodextrin glucanotransferase (Cgt;BsCgt) 2.4.1.19 Geobacillus stearothermophilus ET1 AAD00555.1 Q9ZAQ0   2
 a/β-cyclodextrin glucanotransferase (Cgt;CgtS;Aga2) 2.4.1.19 Geobacillus stearothermophilus No. 2 / NO2 CAA41770.1
CAA41771.1
CAA41772.1
P31797 1CYG[A] 2
 α-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Klebsiella pneumoniae M5a1 AAA25059.1
AAE32693.1
AAP61132.1
AAP61133.1
P08704   2
 maltotriose-producing α-amylase (AmyA) 3.2.1.116 Microbulbifer thermotolerans DAU221 AID53183.1
AMX04264.1
    2
 a/β-cyclodextrin glucanotranferase (Cgt) (fragment) 2.4.1.19 Paenibacillus graminis MC22.13 ACA01964.1 B2XY82   2
 β-cyclodextrin glucanotransferase (CGTase) 2.4.1.19 Paenibacillus illinoisensis ZY-08 / ZY-8 ACO70966.1 C9WB02   2
 α-cyclodextrin glucanotransferase 2.4.1.19 Paenibacillus macerans   P31835   2
 α-cyclodextrin glucanotransferase (partial) 2.4.1.19 Paenibacillus macerans 602-1 AGT21379.1   3WMS[A] 2
 α-cyclodextrin glucanotransferase (CD;Cgt;CgtM) 2.4.1.19 Paenibacillus macerans IAM1243/ IB7 / IFO 3490 (NRRL B-388) / JFB05-01 (CCTCC M203062) CAA41773.1
AAA22298.1
AAC04359.1
O52766
P04830
4JCL[A] 2
 β-cyclodextrin glycosyltransferase (CGTase) 2.4.1.19 Paenibacillus pabuli US132 CAO05752.1     2
 β-cyclodextrin glucanotransferase 2.4.1.19 Paenibacillus sp. A11 AAG31622.1 Q9F5W3   2
 cyclodextrin glucanotransferase 2.4.1.19 Paenibacillus sp. JB-13 ACB71089.1 B2D1U4   2
 cyclomaltodextrin glucanotransferase (AmyA;M5005_Spy_1065) 2.4.1.19 Streptococcus pyogenes MGAS5005 AAZ51683.1     2
 α-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Thermoanaerobacter sp. 5K AJE25826.1     2
 a/β-cyclodextrin glucanotransferase 2.4.1.19 Thermoanaerobacter sp. ATCC 53627 CAJ84380.1     2
 a/β-cyclodextrin glucanotransferase (Cgt) 2.4.1.19 Thermoanaerobacter sp. P4 AJE25827.1     2
 a/β-cyclodextrin glucanotransferase (AmyA) 2.4.1.19 Thermoanaerobacterium thermosulfurigenes EM1 AAB00845.1 P26827 1A47[A]
1CIU[A]
3BMV[A]
3BMW[A]
2
 a/β-cyclodextrin glycosyltransferase (Cgt13;CspCGT13) (partial) 2.4.1.19 uncultured Carboxydocella sp. AIL25792.1     2
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