Glycoside Hydrolase Family 13 / Subf 2

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (289); Uniprot accession (77); PDB accession (54); 3D entries (9); cryst (0)
All (249) Archaea (29) Bacteria (220) Structure (9) Characterized (51)
Archaea
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 α-cyclomaltodextrin glucanotransferase (Cgt) 2.4.1.19 Haloferax mediterranei CAI46245.1 Q53I75   2
 BM92_06580   Haloferax mediterranei ATCC 33500 AHZ22336.1     2
 HFX_0535 (Amyp1)   Haloferax mediterranei ATCC 33500 CGMCC 1.2087 AFK18262.1     2
 Hmuk_0210   Halomicrobium mukohataei DSM 12286 ACV46347.1 C7NWY2   2
 PAP_01075   Palaeococcus pacificus DY20341 AIF68657.1     2
 PFC_01505   Pyrococcus furiosus COM1 AFN03272.1     2
 β-cyclodextrin glucanotransferase (PfCgt;PF0478;PF0478*) 2.4.1.19 Pyrococcus furiosus DSM 3638 ABA33720.1
AAL80602.1
ABA30024.1
ABA30025.1
NP_578207.1
Q3HUR2
Q8U3I8
  2
 PYCH_18540   Pyrococcus yayanosii CH1 AEH25509.1     2
 TBCH5v1_1707   Thermococcus barophilus CH5 ALM75617.1     2
 TERMP_01455   Thermococcus barophilus MP ADT84430.1     2
 A3L01_08030   Thermococcus barossii SHCK-94 ASJ05313.1     2
 A3L02_06140   Thermococcus celer Vu 13 ASI99171.1     2
 CL1_1275   Thermococcus cleftensis AFL95474.1     2
 TEU_01265   Thermococcus eurythermalis A501 AIU69076.1     2
 A3K92_00110   Thermococcus gorgonarius W-12 ASI99994.1     2
 β-cyclodextrin glucanotransferase (Cgt;TK-cgt;TK2172) 2.4.1.19 Thermococcus kodakarensis KOD1 BAB78538.1
BAD86361.1
CAT70763.1
Q8X268   2
 TON_1451   Thermococcus onnurineus NA1 ACJ16941.1 B6YXX8   2
 A3L08_01160   Thermococcus pacificus P-4 ASJ07607.1     2
 TES1_1436   Thermococcus paralvinellae ES1 AHF80814.1     2
 A0127_04445   Thermococcus peptonophilus OG-1 AMQ18471.1     2
 A3L09_02000   Thermococcus profundus DT 5432 ASJ02127.1     2
 A3L10_07420   Thermococcus radiotolerans EJ2 ASJ14969.1     2
 A3L11_01395   Thermococcus siculi RG-20 ASJ07951.1     2
 GQS_08270   Thermococcus sp. 4557 AEK73548.1     2
 CDI07_07550   Thermococcus sp. 5-4 ASA78160.1     2
 α-cyclodextrin glucanotransferase (CgtA) 2.4.1.19 Thermococcus sp. B1001 BAA88217.1
BAB18101.1
CAZ78889.1
Q9UWN2   2
 A3L14_10420   Thermococcus thioreducens OGL-20P ASJ13269.1     2
 Tpen_1454   Thermofilum pendens Hrk 5 ABL78851.1 A1S071   2
 ORF   uncultured marine thaumarchaeote AD1000_100_C06 AIE90996.1     2
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