Glycoside Hydrolase Family 13 / Subf 29

Activities in Sub Familyα-glucosidase (EC 3.2.1.20);
[retaining] a,α-trehalose-6-phosphate hydrolase (EC 3.2.1.93);
Mechanism Retaining a
ClanGH-H
3D Structure Status( β / α ) 8 barrel
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1); Uniprot accession (10); PDB accession (2); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#ReferenceOrganismGenBank UniprotPDB/3DSubf
 trehalose-6-P hydrolase (TreA;BlTreA;BLi00797;BL03069) 3.2.1.93   Bacillus licheniformis DSM 13 = ATCC 14580 AAU39732.1
AAU22384.1
CBF79089.1
Q65MI2 5BRP[A,B,C,D]
5BRQ[A,B,C,D]
29
 α-glucosidase 3.2.1.20   Bacillus sp. DG0303 AAF71997.1 Q9L872   29
 trehalose-6-phosphate hydrolase (TreA;BSU07810) 3.2.1.93 pubmed
Bacillus subtilis subsp. subtilis str. 168 CAB12610.1
AIY92070.1
AQR80734.1
AQR84947.1
CAA56495.1
CAA91015.1
NP_388662.1
A0A6M3Z8J1
P39795
  29
 trehalose-6-phosphate hydrolase (TreC) 3.2.1.93 pubmed
Escherichia coli str. K-12 substr. MG1655 AAC77196.1
AAA24225.1
AAA97136.1
AAC43382.1
AIZ92996.1
ALI38108.1
AMC97092.1
AUG18922.1
AVI54385.1
AYG20987.1
NP_418660.1
P28904   29
 trehalose-6-phosphate hydrolase (TreC;KP1_0530) 3.2.1.93 pubmed
Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 BAG86620.1
BAH61402.1
B6ZN43
C4X1I2
  29
 LBA1014 (TreC;La1014) 3.2.1.93 pubmed
Lactobacillus acidophilus NCFM AAV42863.1
ACH26473.1
Q5FKB1   29
 trehalose-6-phosphate hydrolase (TreA) 3.2.1.93   Pseudomonas fluorescens ATCC 17400 AAG31032.1 Q9F8X2   29
 MGAS10750_Spy1875 (DexS) 3.2.1.93   Streptococcus pyogenes MGAS10750 ABF38825.1 Q1J4B1   29
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