Glycoside Hydrolase Family 13 / Subf 26

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (2379); Uniprot accession (287); PDB accession (2); 3D entries (2); cryst (0)
All (2324) Archaea (34) Bacteria (2289) Eukaryota (1) Structure (2) Characterized (12)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 maltooligosyltrehalose synthase (TreY;MTS) 5.4.99.15 Metallosphaera hakonensis JCM 8857 AAR18371.1 Q6SZP7   26
 maltooligosyltrehalose synthase (TreY;MTSase) 5.4.99.15 Sulfolobus acidocaldarius BAA11009.1
BAA11865.1
Q53688 1IV8[A] 26
 maltooligosyltrehalose synthase (TreY) 5.4.99.15 Sulfolobus shibatae AAF17554.1
AAM81591.1
Q9UWN8   26
 glycosyltrehalose-producing enzyme 5.4.99.15 Sulfolobus solfataricus KM1 BAA11008.1 Q55262   26
 maltooligosyltrehalose synthase (TreY;SSO2095) 5.4.99.15 Sulfolobus solfataricus P2 AAK42274.1
CAA69505.1
NP_343484.1
P95869
Q7LX98
  26
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 malto-oligosyltrehalose synthase (TreY) 5.4.99.15 Actinoplanes sp. SN223/29 ABV26725.1 A8QX07   26
 malto-oligosyltrehalose synthase (MTSase;TreY) 5.4.99.15 Arthrobacter ramosus S34 BAB40765.1 Q9AJN7   26
 maltooligosyltrehalose synthase (TreY) 5.4.99.15 Arthrobacter sp. Q36 BAA09667.1
BAA94843.1
Q44315   26
 maltooligosyltrehalose synthase (TreY;BvMts) 5.4.99.15 Brevibacterium helvolum AAB95368.1 O52519   26
 maltooligosyl trehalose synthase (TreY;CgI2118;cg2323) 5.4.99.15 Corynebacterium glutamicum ATCC 13032 BAB99511.1
ABY16668.1
CAD43536.1
CAF20454.1
CCH25257.1
NP_601318.1
Q8NNR9   26
 maltooligosyltrehalose synthase (TreY) 5.4.99.15 Nostoc punctiforme IAM M-15 BAG85337.1 B6ZIV0   26
 maltooligosyltrehalose synthase (TreY) 5.4.99.15 Rhizobium sp. M-11 BAA11186.1 Q53237   26
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