Glycoside Hydrolase Family 13 / Subf 25

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (246); Uniprot accession (28); PDB accession (2); 3D entries (1); cryst (0)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 glycogen-debranching enzyme (GDE;CgGDE;CAGL0G09977g) 2.4.1.25 Candida glabrata CBS 138 CAG59721.1 Q6FSK0 5D06[A,B]
5D0F[A,B]
25
 glycogen-debranching enzyme 1 (AGL) 2.4.1.25
3.2.1.33
Homo sapiens AAB48466.1
AAB41040.1
AAB48467.1
AAB48468.1
AAB48469.1
AAB48470.1
AAH78663.1
ALC78881.1
ALN12516.1
BAA88405.1
BAD92104.1
BAK64140.1
NP_000019.1
NP_000633.1
NP_000634.1
NP_000635.1
NP_000636.1
NP_000637.1
D3DT51
P35573
  25
 glycogen-debranching enzyme (Agl) 2.4.1.25
3.2.1.33
Oryctolagus cuniculus AAA16364.1 P35574   25
 glycogen-debranching enzyme (YPR184W;Gdb1) 2.4.1.25
3.2.1.33
Saccharomyces cerevisiae S288c AAB68117.1
BAA34996.1
NP_015510.1
Q06625
Q06625
  25
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