Glycoside Hydrolase Family 13 / Subf 24

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (258); Uniprot accession (90); PDB accession (77); 3D entries (4); cryst (0)
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 α-amylase / allergen (Aca s 4) 3.2.1.1 Acarus siro ABL09312.1 B0KZK1   24
 ORF (fragment)   Amblyomma maculatum AEO32115.1     24
 α-amylase (Amy) 3.2.1.1 Anguilla japonica BAB85635.1 Q8QGW2   24
 alpha amylase 2 (Amy2)   Anoplarchus purpurescens AMQ67314.1     24
 α-amylase (fragment)   Anoplarchus purpurescens ABJ97443.1 A0FCQ4   24
 α-amylase allergen (Blo t 4;Blot4)   Blomia tropicalis AAQ24543.1 A1KXI2   24
 Unknown (protein for MGC:128590)   Bos taurus AAI05234.1 Q3MHH8   24
 ORF (fragment)   Callorhinchus milii AFP03741.1     24
 alpha amylase 2 (Amy2)   Cebidichthys violaceus AMQ67308.1     24
 alpha amylase 2 (Amy2)   Cebidichthys violaceus AMQ67309.1     24
 α-amylase (fragment)   Cebidichthys violaceus ABK57091.1 A0MJA3   24
 pancreatic α-amylase (Amy2) (fragment)   Chelon labrosus CAX64421.1 C0MQV6   24
 α-amylase   Chelon labrosus AIC81809.1     24
 ORF (fragment)   Cichlasoma urophthalmum CDJ79882.1     24
 amylase, partial (fragment)   Cirrhinus cirrhosus AHY00276.1     24
 amylase, partial (fragment)   Clarias batrachus ART46312.1     24
 AmY   Colobus angolensis ABW02886.1 A8HDI0   24
 α-amylase B (AmyB;Amy) 3.2.1.1 Crassostrea gigas AAL37207.1
ABB80387.1
ABB80388.1
ABR37235.1
ACC77978.1
ACC77979.1
ACC77980.1
CAD43101.1
CAD43102.1
CAD43103.1
CAD43104.1
Q8I7E4
Q8I7E5
Q8I7E6
Q8I7E7
Q8WSG9
  24
 α-amylase A (AmyA;Amy) 3.2.1.1 Crassostrea gigas AAL37183.1
ACB29736.1
ACC77975.1
ACC77976.1
ACC77977.1
CAA69658.1
CAD43095.1
CAD43096.1
CAD43097.1
CAD43098.1
CAD43099.1
CAD43100.1
O02622
Q8I080
Q8I0T4
Q8I7E8
Q8WSH2
  24
 α-amylase (Amy2A)   Ctenopharyngodon idella ACX35465.1 D0EM61   24
 pancreatic amylase (AmY) (fragment)   Ctenopharyngodon idella ACV04936.1 D4HNE8   24
 α-amylase (fragment)   Ctenopharyngodon idella ADY39424.1     24
 α-amylase (fragment)   Culter alburnus ADY39430.1     24
 α-amylase   Cynoglossus semilaevis AGT37610.1     24
 α-amylase (fragment)   Cyprinus carpio jian AFB76589.1     24
 Unknown (protein for MGC:66313)   Danio rerio AAH54681.1
AAI65756.1
NP_956722.1
Q7SYK9   24
 α-amylase 3 (Amy2A) (pancreatic)   Danio rerio AAH54669.1
AAH62867.1
CAQ15469.1
Q7SYL6   24
 Unknown (protein for MGC:92137)   Danio rerio AAH75900.1 Q6DHR7   24
 allergen (Der f 4)   Dermatophagoides farinae AHX03180.1     24
 Der f 4 allergen (Der_f_4.0107)   Dermatophagoides farinae AIP86945.1     24
 Der f 4 allergen (Der_f_4.0101)   Dermatophagoides farinae AIP86939.1     24
 Der f 4 allergen (Der_f_4.0104)   Dermatophagoides farinae AIP86942.1     24
 Der f 4 allergen (Der_f_4.0106)   Dermatophagoides farinae AIP86944.1     24
 Der f 4 allergen (Der_f_4.0105)   Dermatophagoides farinae AIP86943.1     24
 Der f 4 allergen (Der_f_4.0103)   Dermatophagoides farinae AIP86941.1     24
 Der f 4 allergen (Der_f_4.0108)   Dermatophagoides farinae AIP86946.1     24
 Der f 4 allergen (Der_f_4.0102)   Dermatophagoides farinae AIP86940.1     24
 Der f 4 allergen   Dermatophagoides farinae AJF93907.1     24
 α-amylase (Der p 4;Derp4) (allergen) 3.2.1.1 Dermatophagoides pteronyssinus AAD38942.1 P49274
Q9Y197
  24
 alpha amylase 2 (Amy2)   Dictyosoma burgeri AMQ67310.1     24
 α-amylase 1   Diplodus sargus ABX89620.1 B6CGL7   24
 ORF (fragment)   Dreissena polymorpha AEF56576.1     24
 amylase, partial (fragment)   Dreissena rostriformis bugensis CTQ87316.1     24
 α-amylase   Eisenia fetida BAV13234.1     24
 α-amylase (pancreatic)   Epinephelus coioides ACJ26844.1 D3TJK0   24
 pancreatic α-amylase (Amy2)   Equus caballus AGL52553.1     24
 salivary α-amylase (Amy1)   Equus caballus AGL52552.1     24
 amylase   Eriocheir sinensis ANG56301.1     24
 α-amylase (Eur m 4) (allergen) 3.2.1.1 Euroglyphus maynei AAD38943.1 Q9Y196   24
 pancreatic amylase (fragment)   Felis catus ACO24947.1 C1JYI4   24
 a- amylase (fragment)   Gadus morhua ADG64732.1 D6MXY8   24
 α-amylase (Amy) 3.2.1.1 Gallus gallus AAC60246.1 Q98942   24
 α-amylase (hepatic)   Gallus gallus AAT34994.1 Q6JG52   24
 amylase B (Amy2B) (pancreatic)   Gorilla gorilla gorilla ABW02890.1 A8HDH7   24
 amylase A (Amy2A) (pancreatic)   Gorilla gorilla gorilla ABW02893.1 A8HDH1   24
 amylase (Amy1) (salivary)   Gorilla gorilla gorilla ABW02895.1 A8HDG5   24
 α-amylase 1 (AmyI;HdAmyI) 3.2.1.1 Haliotis discus discus ABO26610.1 B6RB08   24
 α-amylase (HdAmy58) 3.2.1.1 Haliotis discus hannai BAM74656.1     24
 α-amylase   Haliotis gigantea AFQ98378.1     24
 α-amylase   Haliotis tuberculata AFQ98377.1     24
 α-amylase (Amy2A) (pancreatic) 3.2.1.1 Homo sapiens AAA51724.1
AAA51723.1
AAA51725.1
AAA52280.1
AAH07060.1
AAI46998.1
BAD97183.1
CAA30099.1
CAA30100.1
CAN87444.1
NP_000690.1
P04746
P04746
1B2Y[A]
1BSI[A]
1CPU[A]
1HNY[A]
1KB3[A]
1KBB[A]
1KBK[A]
1KGU[A]
1KGW[A]
1KGX[A]
1U2Y[A]
1U30[A]
1U33[A]
1XCW[A]
1XCX[A]
1XD0[A]
1XD1[A]
1XGZ[A]
1XH0[A]
1XH1[A]
1XH2[A]
2CPU[A]
2QMK[A]
2QV4[A]
3BAI[A]
3BAJ[A]
3BAK[A]
3BAW[A]
3BAX[A]
3BAY[A]
3CPU[A]
3IJ7[A]
3IJ8[A]
3IJ9[A]
3OLD[A]
3OLE[A]
3OLG[A]
3OLI[A]
4GQQ[A]
4GQR[A]
4W93[A]
4X9Y[A]
5E0F[A]
5EMY[A]
5KEZ[A]
5TD4[A]
24
 α-amylase (salivary) (Amy1A;Amy1;HSA) 3.2.1.1 Homo sapiens AAH63129.1
AAA16183.1
AAA52279.1
AAA57345.1
AAA58368.1
AAH69347.1
AAH69463.1
AAH70302.1
AAH92444.1
AAI32986.1
AAI32988.1
AAI32996.1
AAI32998.1
AAI44453.1
BAF85030.1
CAI14928.1
CAI14929.1
CAI14930.1
CAI14932.1
NP_004029.2
P04745 1C8Q[A]
1JXJ[A]
1JXK[A]
1MFU[A]
1MFV[A]
1NM9[A]
1Q4N[X]
1SMD[A]
1XV8[A,B]
1Z32[X]
3BLK[A]
3BLP[X]
3DHP[A]
24
 α-amylase C (Amy2B) 3.2.1.1 Homo sapiens AAA35525.1
AAH11179.1
AAH20861.1
BAA14130.1
BAG53093.1
BAG54429.1
NP_066188.1
B3KXB7
D3DT76
P19961
P19961
  24
 ORF (fragment)   Hymenochirus curtipes AEQ17685.1     24
 α-amylase (fragment)   Hypomesus transpacificus ADF80265.1 D6NLA8   24
 α-amylase (fragment)   Hypophthalmichthys molitrix ADY39425.1     24
 α-amylase (fragment)   Hypophthalmichthys nobilis ADY39426.1     24
 α-amylase (HcAMY)   Hyriopsis cumingii AGW45296.1     24
 amylase, partial (fragment)   Labeo rohita AHY00275.1     24
 AmY (fragment)   Lagothrix lagotricha ABW02887.1 A8HDI3   24
 amylase (fragment)   Larimichthys crocea AHK13976.1     24
 α-amylase (pancreatic)   Lates calcarifer AAL84163.1 Q8QGJ0   24
 α-amylase (fragment)   Lingula anatina ACA34391.1 D2YVP9   24
 α-amylase (Amy1)   Lithobius forficatus ACA34374.1
AAO17926.1
D2YVN2
Q8I9P9
  24
 α-amylase (Amy4) (fragment)   Litopenaeus vannamei CAB63937.1 Q9U0F7   24
 α-amylase 1 3.2.1.1 Litopenaeus vannamei CAA54524.1
AAR19061.1
Q26193   24
 α-amylase (Amy) 3.2.1.1 Litopenaeus vannamei CAB65553.1
AAR19062.1
CAD43060.1
Q9U0F6   24
 α-amylase (Amy) 3.2.1.1 Litopenaeus vannamei CAB65552.2 Q9U0F9   24
 amylase   Litopenaeus vannamei AIJ02083.1     24
 α-amylase (fragment)   Luciobrama macrocephalus ADY39432.1     24
 amylase, partial (fragment)   Lutjanus guttatus AIS23634.1     24
 pancreatic α-amylase precursor (Amy2B)   Macaca mulatta AFE66952.1
AFH29027.1
AFI35759.1
    24
 pancreatic α-amylase precursor (Amy2A)   Macaca mulatta AFJ70167.1     24
 pancreatic α-amylase precursor (Amy2A)   Macaca mulatta AFJ70125.1     24
 α-amylase   Marsupenaeus japonicus AHN91843.1
AHN91844.1
    24
 α-amylase (fragment)   Megalobrama amblycephala ADY39428.1     24
 α-amylase   Meretrix meretrix ALG64482.1     24
 α-amylase 3.2.1.1 Mus musculus AAA37221.1
AAA37219.1
AAA37220.1
AAH04698.1
AAH09121.1
BAC26543.1
CAA24097.1
CAA24099.1
CAA24100.1
NP_031472.1
P00687
Q921Y7
Q99KE6
  24
 α-amylase 3.2.1.1 Mus musculus AAA37230.1
AAA37222.1
AAA37223.1
AAA37224.1
AAA37225.1
AAA37226.1
AAA37227.1
AAA37228.1
AAA37229.1
AAA37232.1
AAA37233.1
AAH94924.1
AAI00580.1
BAC37484.1
BAE21706.1
CAA24098.1
CAA26202.1
CAA26413.1
CAA26414.1
CAA26415.1
CAA26417.1
CAA26418.1
NP_033799.1
P00688
Q61297
Q61298
Q61299
Q8C5B4
  24
 ORF (fragment)   Mustela putorius furo AES10950.1     24
 pancreatic amylase alpha 2A (fragment)   Mylopharyngodon piceus ADY39423.1     24
 salivary α-amylase   Myodes glareolus ABB96226.1 Q2V6H2   24
 α-amylase   Myxocyprinus asiaticus ABQ45553.1 A5JTT8   24
 α-amylase, partial (fragment)   Neohelice granulata APQ41574.1     24
 α-amylase (fragment)   Opsariichthys bidens ADY39431.1     24
 α-amylase (partial) 3.2.1.1 Oryzias latipes     3VM5[A] 24
 amylase   Pagrus major BAL14133.1     24
 α-amylase (Amy1) (fragment)   Pagrus pagrus AAU93830.1 Q5XPY5   24
 amylase B (Amy2B) (pancreatic)   Pan paniscus ABW02889.1 A8HDH5   24
 amylase A (Amy2A) (pancreatic)   Pan paniscus ABW02892.1 A8HDH0   24
 amylase B (Amy2B) (pancreatic)   Pan troglodytes troglodytes ABW02888.1 A8HDH3   24
 amylase A (Amy2A) (pancreatic)   Pan troglodytes troglodytes ABW02891.1
CAG28985.1
A8HDG8   24
 amylase (Amy1;Amy1A) (salivary)   Pan troglodytes troglodytes ABW02894.1
CAG28984.1
A8HDG3   24
 amylase (fragment)   Pangasianodon hypophthalmus BAT70077.1     24
 amylase, partial (fragment)   Pangasianodon hypophthalmus BAT70077.1     24
 α-amylase (Pre-amylasE)   Panulirus argus CDU84835.1     24
 α-amylase 3.2.1.1 Pecten maximus CAA68065.1 P91778   24
 α-amylase (potential fragment)   Pelophylax nigromaculatus AHJ09866.1     24
 amylase (fragment)   Pelteobagrus fulvidraco AAX37668.1 Q58LW4   24
 alpha amylase 2 (Amy2)   Phytichthys chirus AMQ67313.1     24
 amylase   Pinctada fucata AGN55419.1
AGN55420.1
    24
 amylase   Pinctada maxima AEI58897.1
AFD28988.1
    24
 α-amylase   Platynereis dumerilii AIZ77504.1     24
 amylase, partial   Procambarus clarkii AKN79742.1     24
 α-amylase (Amy2A) 3.2.1.1 Pseudopleuronectes americanus AAF65827.1 Q9I9H6   24
 amylase   Pteria penguin AEI58894.1     24
 α-amylase (Amy1) 3.2.1.1 Rattus norvegicus AAA40725.1
AAA40731.1
NP_113690.1
P00689   24
 α-amylase (Amy1) 3.2.1.1 Rattus norvegicus AAH88228.1
BAB39466.1
Q5I0L0
Q99N59
  24
 α-amylase   Saccostrea forskali AHA11414.1     24
 α-amylase   Salmo salar ABD13895.1 A0SEG1   24
 amylase, alpha 2A, partial (Amy2A) (fragment)   Scaphiopus couchii AEZ53693.1     24
 amylase, alpha 2A, partial (Amy2A) (fragment)   Scaphiopus holbrookii AEZ53694.1     24
 α-amylase   Siganus canaliculatus AHN13897.1
AKA86463.1
    24
 α-amylase (pancreatic)   Siniperca chuatsi ACH53601.1
ACJ06746.1
D3TJH5   24
 amylase, partial (fragment)   Solea senegalensis ASW27225.1     24
 α-amylase, partial (fragment)   Solea solea AGS43576.1     24
 α-amylase (Amy2A)   Sparus aurata ALB35087.1     24
 amylase, alpha 2A, partial (Amy2A) (fragment)   Spea bombifrons AEZ53691.1     24
 amylase, alpha 2A, partial (Amy2A) (fragment)   Spea multiplicata AEZ53692.1     24
 α-amylase   Spondylus violaceus AFE48186.1     24
 α-amylase (fragment)   Squaliobarbus curriculus ADY39427.1     24
 α-amylase (PA) (pancreatic) 3.2.1.1 Struthio camelus   P83053   24
 α-amylase (Ppa;PPA) (pancreatic) 3.2.1.1 Sus scrofa AAF02828.1 P00690 1BVN[P]
1DHK[A]
1HX0[A]
1JFH[A]
1KXQ[A]
1KXT[A]
1KXV[A]
1OSE[A]
1PIF[A]
1PIG[A]
1PPI[A]
1UA3[A]
1VAH[A]
1WO2[A]
3L2L[A]
3L2M[A]
4X0N[A]
24
 amylase-1 3.2.1.1 Tetraodon nigroviridis CAC87125.1 Q8UWE5   24
 amylase-2   Tetraodon nigroviridis CAC87126.1 Q8UWE4   24
 amylase-3 3.2.1.1 Tetraodon nigroviridis CAC87127.1 Q8UWE3   24
 amylase   Tetraodon nigroviridis CAD20312.1
CAD20263.1
Q8QFS2   24
 amylase-2   Thunnus orientalis BAL14132.1     24
 amylase-1   Thunnus orientalis BAL14131.1     24
 α-amylase (Amy2) (fragment)   Thunnus thynnus CAX33863.1 B9WPP5   24
 mite allergen (Tyr p 4)   Tyrophagus putrescentiae ABM53754.1 B0KZL5   24
 α-amylase (fragment)   Xenocypris argentea ADY39429.1     24
 pancreatic α-amylase (fragment)   Xenopus laevis AAL87102.1 Q8QGF5   24
 Mgc64337   Xenopus laevis AAH56841.1 Q6PGT2   24
 Unknown (protein for MGC:116539)   Xenopus laevis AAH99344.1 Q4FZM9   24
 Unknown (protein for MGC:89676)   Xenopus tropicalis AAH80454.1
CAJ83859.1
Q66KD1   24
 Unknown (protein for IMAGE:7625771)   Xenopus tropicalis AAI35719.1
AAI58293.1
A4QNI3   24
 alpha amylase 2 (Amy2)   Xiphister atropurpureus AMQ67312.1     24
 α-amylase (fragment)   Xiphister atropurpureus ABJ97444.1 A0FCQ5   24
 alpha amylase 2 (Amy2)   Xiphister mucosus AMQ67311.1     24
 α-amylase (fragment)   Xiphister mucosus ABJ97442.1 A0FCQ3   24
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