Glycoside Hydrolase Family 13 / Subf 22

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (72); Uniprot accession (28);
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 α-1,3-glucan synthase (Ags1) 2.4.1.183 Aspergillus fumigatus AAL28129.1 Q96UQ6   22
 Ags2   Aspergillus fumigatus AAL18964.1 Q96UR0   22
 α-1,3-glucan synthase (AGS3;Afu1g15440) 2.4.1.183 Aspergillus fumigatus Af293 EAL90874.1 Q4WRQ8   22
 α-1,3-glucan synthase (AgsA;AN5885;ANID5885) 2.4.1.183 Aspergillus nidulans FGSC A4 EAA58394.1 C8UZW7
Q5B0P5
  22
 α-1,3-glucan synthase (AgsB;AN3307;ANID3307) 2.4.1.183 Aspergillus nidulans FGSC A4 EAA63275.1 C8VHZ4
Q5B823
  22
 An02g03260 (AgsD)   Aspergillus niger CBS 513.88 CAK47606.1 A2QCE2   22
 An04g09890 (AgsA)   Aspergillus niger CBS 513.88 CAK39048.1 A2QKA2   22
 An09g03070 (AgsE)   Aspergillus niger CBS 513.88 CAK40246.1 A2QTS1   22
 An12g02450 (AgsC)   Aspergillus niger CBS 513.88 CAK41087.1 A2QYT8   22
 An15g07810 (AgsB)   Aspergillus niger CBS 513.88 CAK42668.1 A2R6G0   22
 α-1,3-glucan synthase (AgsA) 2.4.1.183 Aspergillus niger N402 CAD88949.1
AAS99324.1
    22
 AO090003001500   Aspergillus oryzae RIB40 BAE58541.1 Q2UIS4   22
 AO090026000523   Aspergillus oryzae RIB40 BAE59959.1 Q2UEQ6   22
 AO090010000106   Aspergillus oryzae RIB40 BAE66017.1 Q2TXK6   22
 Bofut4_p114550.1   Botrytis cinerea T4 CCD46749.1     22
 CGB_G0300C   Cryptococcus gattii WM276 ADV23282.1     22
 CNAG_03120   Cryptococcus neoformans var. grubii H99 AFR96345.1
AFR96345.2
AGV14519.1
    22
 α-1,3-glucan synthase (Ags1;CNG04420) 2.4.1.183 Cryptococcus neoformans var. neoformans JEC21 AAW44814.1
AAR97368.1
Q5KDD1   22
 α-1,3-glucan synthase (Ags1;HCBG_04272) 2.4.1.183 Histoplasma capsulatum G186AR EEH07393.1     22
 α-1,3-glucan synthase (Ags1;MgAGS1;MG09639;MGG_09639) 2.4.1.183 Magnaporthe oryzae 70-15 EAA48102.1
XP_003721444.1
XP_364794.1
    22
 NCU02478.1 (B1O14.220)   Neurospora crassa OR74A CAE76407.1
XP_331677.1
Q7SG86   22
 NCU08132.1   Neurospora crassa OR74A XP_328838.1     22
 α-1,3-glucan synthase (Ags1;AGS1) 2.4.1.183 Paracoccidioides brasiliensis Pb01 / ATCC-MYA-826 AAV52833.1 Q5S3X6   22
 Pc16g06130   Penicillium rubens Wisconsin 54-1255 CAP93283.1 B6H8S9   22
 Pc21g10560   Penicillium rubens Wisconsin 54-1255 CAP95953.1 B6HIZ1   22
 Pc15g00500   Penicillium rubens Wisconsin 54-1255 CAP82936.1 B6H6J6   22
 Pc22g15390   Penicillium rubens Wisconsin 54-1255 CAP98827.1 B6HVZ7   22
 unnamed protein product   Podospora anserina S mat+ CAP61823.1
CDP28899.1
B2AEF7   22
 unnamed protein product   Podospora anserina S mat+ CAP62025.1
CDP29101.1
B2AF08   22
 SPAC23D3.15 (Mok11)   Schizosaccharomyces pombe 972h- CAB90796.2
BAA76557.1
CAA91250.1
NP_594552.1
Q09854
Q09854
  22
 α-1,3-glucan synthase (Mok12;Pi011;SPBC32H8.13C) 2.4.1.183 Schizosaccharomyces pombe 972h- CAC37503.1
BAA21388.1
BAA76558.1
NP_595619.1
Q9UUL4   22
 α-1,3-glucan synthase (Mok13;SPBC16D10.05) 2.4.1.183 Schizosaccharomyces pombe 972h- BAA76559.1
CAB38509.1
NP_596500.1
Q9Y719   22
 α-1,3-/α-1,4-glucan synthase (Ags1;Mok1;SPCC1281.01;SPCC338.01C;SPCC17A7.01) 2.4.1.-
2.4.1.183
Schizosaccharomyces pombe 972h- AAC31430.1
BAA34054.1
CAA19332.1
CAA19332.2
NP_588165.1
Q9USK8   22
 sscle_07g056980   Sclerotinia sclerotiorum 1980 UF-70 APA10928.1     22
 PIIN_02347 (fragment)   Serendipita indica DSM 11827 CCA68483.1     22
 PIIN_11844 (fragment)   Serendipita indica DSM 11827 CCA68864.1     22
 MYCTH_108416   Thermothelomyces thermophila ATCC 42464 AEO58445.1     22
 a--glucan synthase   Xanthophyllomyces dendrorhous CED84111.1     22
 modular protein with glycoside hydrolase family 13 and glycosyltransferase family 5 domains   Xanthophyllomyces dendrorhous CED84497.1     22
 ZT1A5_G4034   Zymoseptoria tritici ST99CH_1A5 SMY22594.1     22
 ZT1A5_G6398   Zymoseptoria tritici ST99CH_1A5 SMY24956.1     22
 ZT1A5_G1839   Zymoseptoria tritici ST99CH_1A5 SMY20404.1     22
 ZT1E4_G4105   Zymoseptoria tritici ST99CH_1E4 SMR48713.1     22
 ZT1E4_G1853   Zymoseptoria tritici ST99CH_1E4 SMR43075.1     22
 ZT1E4_G6486   Zymoseptoria tritici ST99CH_1E4 SMR53211.1     22
 ZT3D1_G3995   Zymoseptoria tritici ST99CH_3D1 SMR49898.1     22
 ZT3D1_G6381   Zymoseptoria tritici ST99CH_3D1 SMR54883.1     22
 ZT3D1_G1825   Zymoseptoria tritici ST99CH_3D1 SMR45241.1     22
 ZT3D7_G4043   Zymoseptoria tritici ST99CH_3D7 SMQ48893.1     22
 ZT3D7_G6460   Zymoseptoria tritici ST99CH_3D7 SMQ51307.1     22
 ZT3D7_G1863   Zymoseptoria tritici ST99CH_3D7 SMQ46717.1     22
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