Glycoside Hydrolase Family 13 / Subf 22

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (66); Uniprot accession (28);
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-1,3-glucan synthase (Ags1) 2.4.1.183
2.4.1.183
Aspergillus fumigatus AAL28129.1 Q96UQ6   22
 α-1,3-glucan synthase (AGS3;Afu1g15440) 2.4.1.183 Aspergillus fumigatus Af293 EAL90874.1 Q4WRQ8   22
 α-1,3-glucan synthase (AgsA;AN5885;ANID5885) 2.4.1.183
2.4.1.183
Aspergillus nidulans FGSC A4 EAA58394.1 C8UZW7
Q5B0P5
  22
 α-1,3-glucan synthase (AgsB;AN3307;ANID3307) 2.4.1.183
2.4.1.183
Aspergillus nidulans FGSC A4 EAA63275.1 C8VHZ4
Q5B823
  22
 α-1,3-glucan synthase (AgsA) 2.4.1.183 Aspergillus niger N402 CAD88949.1
AAS99324.1
    22
 α-1,3-glucan synthase (Ags1;CNG04420) 2.4.1.183 Cryptococcus neoformans var. neoformans JEC21 AAW44814.1
AAR97368.1
Q5KDD1   22
 α-1,3-glucan synthase (Ags1;HCBG_04272) 2.4.1.183
2.4.1.183
Histoplasma capsulatum G186AR EEH07393.1     22
 α-1,3-glucan synthase (Ags1;MgAGS1;MG09639;MGG_09639) 2.4.1.183 Magnaporthe oryzae 70-15 EAA48102.1
XP_003721444.1
XP_364794.1
    22
 α-1,3-glucan synthase (Ags1;AGS1) 2.4.1.183
2.4.1.183
Paracoccidioides brasiliensis Pb01 / ATCC-MYA-826 AAV52833.1 Q5S3X6   22
 α-1,3-glucan synthase (Mok12;Pi011;SPBC32H8.13C) 2.4.1.183
2.4.1.183
Schizosaccharomyces pombe 972h- CAC37503.1
BAA21388.1
BAA76558.1
NP_595619.1
Q9UUL4   22
 α-1,3-glucan synthase (Mok13;SPBC16D10.05) 2.4.1.183 Schizosaccharomyces pombe 972h- BAA76559.1
CAB38509.1
NP_596500.1
Q9Y719   22
 α-1,3-/α-1,4-glucan synthase (Ags1;Mok1;SPCC1281.01;SPCC338.01C;SPCC17A7.01) 2.4.1.-
2.4.1.183
2.4.1.183
Schizosaccharomyces pombe 972h- AAC31430.1
BAA34054.1
CAA19332.1
CAA19332.2
NP_588165.1
Q9USK8   22
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