Glycoside Hydrolase Family 13 / Subf 19

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1685); Uniprot accession (118);
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase I (AmyI) (alkaline;thermostable) 3.2.1.1 Bacillus halodurans 38C-2-1 BAF93484.1 A8QWV3   19
 α-amylase G-6 (BH0413) 3.2.1.98 Bacillus halodurans C-125 BAB04132.1
NP_241279.1
Q9KFR4   19
 maltohexaose-forming α-amylase (Amy 34) 3.2.1.98 Bacillus halodurans LBK 34 AAS99099.1 Q5GIA5   19
 maltotetraose-producing α-amylase (AmyA) (alkaline, thermotolerant) 3.2.1.60 Bacillus halodurans MS-2-5 BAG70894.1 B5MEM6   19
 maltohexaose-forming amylase (G6-amylase) 3.2.1.98 Bacillus sp. H-167 CAA39096.1 Q45574   19
 α-amylase (MalS;b3571) 3.2.1.1 Escherichia coli str. K-12 substr. MG1655 AAB18548.1
AAC76595.1
AIZ93631.1
ALI38743.1
AMC96456.1
CAA41740.1
NP_418028.1
P25718   19
 maltohexaose-forming α-amylase (AmyG6) 3.2.1.98 Klebsiella pneumoniae BAA88434.1 Q9RHR1   19
 maltopentaose-forming amylase 3.2.1.- unidentified bacterium UGO163/26 / DSM 5853 CAA37453.1 Q03658   19
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