Glycoside Hydrolase Family 13 / Subf 19

Activities in Familyα-amylase (EC; pullulanase (EC; cyclomaltodextrin glucanotransferase (EC; cyclomaltodextrinase (EC; trehalose-6-phosphate hydrolase (EC; oligo-α-glucosidase (EC; maltogenic amylase (EC; neopullulanase (EC; α-glucosidase (EC; maltotetraose-forming α-amylase (EC; isoamylase (EC; glucodextranase (EC; maltohexaose-forming α-amylase (EC; maltotriose-forming α-amylase (EC; branching enzyme (EC; trehalose synthase (EC; 4-α-glucanotransferase (EC; maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC ; sucrose phosphorylase (EC; malto-oligosyltrehalose trehalohydrolase (EC; isomaltulose synthase (EC; malto-oligosyltrehalose synthase (EC; amylo-α-1,6-glucosidase (EC; α-1,4-glucan: phosphate α-maltosyltransferase (EC; 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (1607); Uniprot accession (118);
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 α-amylase I (AmyI) (alkaline;thermostable) Bacillus halodurans 38C-2-1 BAF93484.1 A8QWV3   19
 α-amylase G-6 (BH0413) Bacillus halodurans C-125 BAB04132.1
Q9KFR4   19
 maltohexaose-forming α-amylase (Amy 34) Bacillus halodurans LBK 34 AAS99099.1 Q5GIA5   19
 maltotetraose-producing α-amylase (AmyA) (alkaline, thermotolerant) Bacillus halodurans MS-2-5 BAG70894.1 B5MEM6   19
 maltohexaose-forming amylase (G6-amylase) Bacillus sp. H-167 CAA39096.1 Q45574   19
 α-amylase (MalS;b3571) Escherichia coli str. K-12 substr. MG1655 AAB18548.1
P25718   19
 maltohexaose-forming α-amylase (AmyG6) Klebsiella pneumoniae BAA88434.1 Q9RHR1   19
 maltopentaose-forming amylase 3.2.1.- unidentified bacterium UGO163/26 / DSM 5853 CAA37453.1 Q03658   19

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