Glycoside Hydrolase Family 13 / Subf 17

Activities in Sub Family	α-glucosidase (EC 3.2.1.20);[retaining] sucrose α-glucosidase (EC 3.2.1.48)
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) ₈ barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (486); Uniprot accession (19); PDB accession (10); 3D entries (3); cryst (1)

Eukaryota

Protein Name

EC#

Organism

GenBank

Uniprot

PDB/3D

Carbohydrate Ligands

Resolution (Å)

Subf

α-glucosidase III (Hbg3; HBG-III; Loc406131)

BAA11466.1
BAE86928.1
CBF79234.1
NP_001011608.1
XP_392790.1

cryst

sucrose hydrolase (BmSUH)

Bombyx mori

6LGA[A,B]		1.85
6LGB[A,B]	α-D-Glcp	1.70
6LGC[A,B]	<carb_like_NOJ>	1.90
6LGD[A,B]	<carb_like_1AB>	1.75
6LGE[A,B]	<non_carb>-(1-4)-α-D-6-deoxy-Glcp4N-(1-4)-α-D-Glcp-(1-4)-β-D-Glcp	1.75
6LGF[A,B]	α-D-Glcp-(1-2)-β-D-Fruf	1.85
6LGG[A,B]	α-D-Glcp-(1-2)-β-D-Fruf	1.84
6LGH[A,B]	β-D-Glcp-(1-4)-ASP	1.70
6LGI[A,B]	β-D-Fruf β-D-Frup β-D-Glcp-(1-4)-ASP	1.60

binary toxin receptor protein (Cqm1)

1.81