Glycoside Hydrolase Family 13 / Subf 17

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (248); Uniprot accession (58); PDB accession (0); 3D entries (1); cryst (1)
All (143) Eukaryota (143) Structure (1 - 1 cryst) Characterized (18)
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 sucrase / α-glucosidase (S1;APS1) 3.2.1.20 Acyrthosiphon pisum ABB55878.1 Q0H3F1   17
 α-amylase (Aamy1) 3.2.1.20 Anopheles albimanus ADD81256.1 D4N3A2   17
 α-glucosidase (Agm1) 3.2.1.20 Anopheles gambiae G3 CAA60857.1 Q17021   17
 α-glucosidase (Agm2) 3.2.1.20 Anopheles gambiae G3 CAA60858.1
CBF79157.1
Q17022   17
 α-glucosidase / binding-toxin receptor (Agm3;AgAgm3) 3.2.1.20 Anopheles gambiae G3 ABW98683.1 A9YDV2   17
 α-glucosidase 3.2.1.20 Apis cerana indica ABO27432.1 A4GVI6   17
 sucrase / α-glucosidase II (JBgII;HBGaseII) 3.2.1.20
3.2.1.-
Apis cerana japonica ACN63343.1 C0LQJ2   17
 α-glucosidase I (JBgI) 3.2.1.20 Apis cerana japonica BAF44218.1 A1IHL0   17
 α-glucosidase III 3.2.1.20 Apis dorsata ADB11049.1 D2XNP9   17
 α-glucosidase III (Hbg3;HBG-III;Loc406131) 3.2.1.20 Apis mellifera BAA11466.1
BAE86928.1
CBF79234.1
NP_001011608.1
XP_392790.1
Q17058 cryst 17
 α-glucosidase I (Hbg1;HBG-I;Loc409889) 3.2.1.20 Apis mellifera BAE86926.1
XP_393379.2
Q25BT8   17
 α-glucosidase II (Hbg2;HBG-II;Loc411257) 3.2.1.20 Apis mellifera BAE86927.1
CBF79049.1
XP_394730.1
Q25BT7   17
 α-glucosidase / maltase 1 (Cpm1) (binary toxin-binding) 3.2.1.20 Culex pipiens AAL05443.1 Q95WY5   17
 α-glucosidase D (LvpD) 3.2.1.20 Drosophila melanogaster AAF59088.1
AAL49188.1
CAA23492.1
NP_476625.2
P07191
P07191
  17
 α-glucosidase H (LvpH; RE72980p) 3.2.1.20 Drosophila melanogaster AAF59089.3
AAF59089.2
AAL48097.2
CAA23491.1
NP_476627.1
P07190   17
 α-glucosidase L (LvpL) 3.2.1.20 Drosophila melanogaster AAM50308.1
AAF59087.2
CAA23493.1
NP_476628.2
P07192
P07192
  17
 α-glucosidase 1 (Mav1) 3.2.1.20 Drosophila virilis AAB82327.1
CAZ78900.1
CBF79236.1
O16098   17
 α-glucosidase 2 (Mav2) 3.2.1.20 Drosophila virilis AAB82328.1
CBF79239.1
O16099   17
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