Glycoside Hydrolase Family 13 / Subf 17

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (248); Uniprot accession (58); PDB accession (0); 3D entries (1); cryst (1)
All (143) Eukaryota (143) Structure (1 - 1 cryst) Characterized (18)
Eukaryota
Protein Name EC#Organism GenBankUniprotPDB/3DSubf
 sucrase / α-glucosidase (S1;APS1) 3.2.1.20 Acyrthosiphon pisum ABB55878.1 Q0H3F1   17
 ACYPI000002 (fragment)   Acyrthosiphon pisum LSR1 BAH72291.1 C4WWM1   17
 α-glucosidase (Mal1;MalI; AAEL009524-PA)   Aedes aegypti AAA29352.1
AAA29351.1
ABM68601.1
ACC76784.1
ACC76785.1
ACC76786.1
CBF79241.1
P13080   17
 α-glucosidase (Aam1;AaeL_AAEL010537)   Aedes aegypti Liverpool XP_001660909.1     17
 ORF   Aedes albopictus AAV90637.1
CAZ78874.1
Q5MIZ5   17
 α-amylase (Aamy1) 3.2.1.20 Anopheles albimanus ADD81256.1 D4N3A2   17
 salivary ORF (fragment)   Anopheles darlingi ACI30110.1 B6DDW3   17
 salivary maltase   Anopheles darlingi ACI30102.1 B7T4S1   17
 α-glucosidase (Agm1) 3.2.1.20 Anopheles gambiae G3 CAA60857.1 Q17021   17
 α-glucosidase (Agm2) 3.2.1.20 Anopheles gambiae G3 CAA60858.1
CBF79157.1
Q17022   17
 α-glucosidase / binding-toxin receptor (Agm3;AgAgm3) 3.2.1.20 Anopheles gambiae G3 ABW98683.1 A9YDV2   17
 unnamed protein product   Anopheles gambiae str. PEST CAZ78774.1     17
 unnamed protein product (fragment)   Anopheles gambiae str. PEST CAZ78775.1     17
 α-amylase   Antheraea pernyi Shenhuang No.2 AJR29308.1     17
 α-glucosidase (Hbg2) (fragment)   Apis cerana cerana ABR24827.1 A6NAF4   17
 α-glucosidase II   Apis cerana indica AFR59339.1     17
 α-glucosidase I   Apis cerana indica AGE11865.1     17
 α-glucosidase 3.2.1.20 Apis cerana indica ABO27432.1 A4GVI6   17
 sucrase / α-glucosidase II (JBgII;HBGaseII) 3.2.1.20
3.2.1.-
Apis cerana japonica ACN63343.1 C0LQJ2   17
 α-glucosidase III (JBgIII)   Apis cerana japonica ACQ45697.1 C3VPV8   17
 α-glucosidase I (JBgI) 3.2.1.20 Apis cerana japonica BAF44218.1 A1IHL0   17
 α-glucosidase III 3.2.1.20 Apis dorsata ADB11049.1 D2XNP9   17
 α-glucosidase III (Hbg3;HBG-III;Loc406131) 3.2.1.20 Apis mellifera BAA11466.1
BAE86928.1
CBF79234.1
NP_001011608.1
XP_392790.1
Q17058 cryst 17
 α-glucosidase I (Hbg1;HBG-I;Loc409889) 3.2.1.20 Apis mellifera BAE86926.1
XP_393379.2
Q25BT8   17
 α-glucosidase II (Hbg2;HBG-II;Loc411257) 3.2.1.20 Apis mellifera BAE86927.1
CBF79049.1
XP_394730.1
Q25BT7   17
 maltase D   Bactrocera dorsalis AIT38256.1
AKG06610.1
    17
 glucohydrolase GH13-1, partial (fragment)   Bemisia tabaci AQU43105.1     17
 ORF (fragment)   Bemisia tabaci AID65143.1     17
 α-glucosidase (Bdg3)   Bombus diversus diversus BAI44029.1 C9K1M5   17
 α-glucosidase (Big3)   Bombus ignitus BAI44030.1 C9K1M6   17
 α-amylase   Bombyx mori ACJ49024.1 D8KY55   17
 sucrose hydrolase (BmSuh)   Bombyx mori BAP18683.1     17
 ORF   Callorhinchus milii AFO96573.1     17
 α-glucosidase (CjapalphaGlu)   Camponotus japonicus BAO48210.1     17
 ORF (fragment)   Coptotermes formosanus AGM32281.1     17
 ORF (fragment)   Coptotermes formosanus AGM32321.1     17
 ORF (fragment)   Coptotermes formosanus AGM32822.1     17
 ORF (fragment)   Coptotermes formosanus AGM32823.1     17
 α-glucosidase / maltase 1 (Cpm1) (binary toxin-binding) 3.2.1.20 Culex pipiens AAL05443.1 Q95WY5   17
 maltase 1 (Cpm1) (fragment)   Culex pipiens BP ABN64095.1 A4KVA0   17
 maltase 1 (Cpm1) (possible frameshift)   Culex pipiens BP ABN64096.1 A4KVA1   17
 maltase 1 (Cpm1)   Culex pipiens S-LAB ABN64094.1 A4KV99   17
 binary toxin receptor protein   Culex quinquefasciatus ASO96882.1     17
 binary toxin receptor protein   Culex quinquefasciatus ASO96881.1     17
 α-glucosidase / maltase 1 (Cqm1) (mid-gut)   Culex quinquefasciatus ABC59609.1 Q1PQK2   17
 salivary α-glucosidase   Culex tarsalis ACJ64288.1 B8RIZ0   17
 α-glucosidase (fragment)   Culex tarsalis ACJ64310.1 C4N154   17
 maltase   Culicoides nubeculosus ACM40914.1 B9URL7   17
 maltase / allergen (Cul n 8)   Culicoides nubeculosus ADJ67272.1 D9IL18   17
 maltase / allergen (Cul o 1)   Culicoides obsoletus AGI16774.1     17
 maltase / allergen (Mal1;CsMAL1;Cul s 1)   Culicoides sonorensis AAU06480.1 Q66UC5   17
 ORF (fragment)   Culicoides sonorensis AAV84200.1 Q5QBM4   17
 rBAT protein (RbaT)   Cyprinus carpio AEX13745.1     17
 DKEY-202M23.2-001 (partial)   Danio rerio CAX14245.1 B8JJX3   17
 unknown (fragment)   Dendroctonus ponderosae AEE61835.1     17
 sucrase (fragment)   Diuraphis noxia AEP03183.1
AFK66761.1
    17
 Dbus_chr2Rg503   Drosophila busckii ALC40924.1     17
 Dbus_chr2Lg1433 (fragment)   Drosophila busckii ALC39348.1     17
 Dbus_chr2Rg506   Drosophila busckii ALC40927.1     17
 Dbus_chr2Rg511   Drosophila busckii ALC40932.1     17
 Dbus_chr2Rg507   Drosophila busckii ALC40928.1     17
 Dbus_chr2Rg505 (fragment)   Drosophila busckii ALC40926.1     17
 Dbus_chr2Rg510   Drosophila busckii ALC40931.1     17
 Dbus_chr2Rg508   Drosophila busckii ALC40929.1     17
 Dbus_chr2Rg509   Drosophila busckii ALC40930.1     17
 α-glucosidase D (LvpD) 3.2.1.20 Drosophila melanogaster AAF59088.1
AAL49188.1
CAA23492.1
NP_476625.2
P07191
P07191
  17
 α-glucosidase H (LvpH; RE72980p) 3.2.1.20 Drosophila melanogaster AAF59089.3
AAF59089.2
AAL48097.2
CAA23491.1
NP_476627.1
P07190   17
 α-glucosidase L (LvpL) 3.2.1.20 Drosophila melanogaster AAM50308.1
AAF59087.2
CAA23493.1
NP_476628.2
P07192
P07192
  17
 CG30360   Drosophila melanogaster AAM68846.1
AAM68846.2
AAS64893.1
AAS64893.2
AAY55205.1
AAY55241.1
AEQ72803.1
CBF79036.1
NP_724679.1
A1Z7F1
Q4V531
  17
 CG14934   Drosophila melanogaster AAF53127.1
AAY55235.1
AAY55260.1
ACH92362.1
NP_609522.1
Q9VKE6   17
 CG14935   Drosophila melanogaster AAF53128.2
AAF53128.3
AAN10789.1
ABY20539.1
ACT67257.1
ADV37041.1
AEW68188.1
CBF78950.1
NP_609523.2
NP_723693.1
Q8IPA2
Q9VKE5
  17
 CG8690   Drosophila melanogaster AAF59083.2
AAM50891.1
AFA28424.1
NP_610384.1
A1Z7F3
Q8MS80
  17
 CG11669   Drosophila melanogaster AAF59084.2
AEA30986.1
AHN55996.1
NP_610383.1
A1Z7F2   17
 CG30359   Drosophila melanogaster AAV36953.1
AAF59085.2
AAL39303.1
ACZ94367.1
AHN55995.1
NP_610382.2
Q5U124
Q8T0N3
  17
 CG8693   Drosophila melanogaster AAF59086.1
ABY20547.1
NP_610381.1
A1Z7E8   17
 α-glucosidase 1 (Mav1) 3.2.1.20 Drosophila virilis AAB82327.1
CAZ78900.1
CBF79236.1
O16098   17
 α-glucosidase 2 (Mav2) 3.2.1.20 Drosophila virilis AAB82328.1
CBF79239.1
O16099   17
 ORF   Musca domestica ALHF AFP60283.1     17
 ORF   Musca domestica ALHF AFP59562.1     17
 ORF   Musca domestica ALHF AFP61790.1     17
 ORF   Musca domestica ALHF AFP62021.1     17
 ORF   Musca domestica ALHF AFP62166.1     17
 ORF (fragment)   Musca domestica ALHF AFP62143.1     17
 ORF (fragment)   Musca domestica ALHF AFP62365.1     17
 ORF (fragment)   Musca domestica ALHF AFP62760.1     17
 ORF (fragment)   Musca domestica ALHF AFP63944.1     17
 ORF (fragment)   Musca domestica ALHF AFP64434.1     17
 sucrase, partial (Suc1)   Myzus persicae AKM95031.1     17
 sucrase, partial (Su1) (fragment)   Nilaparvata bakeri AGE93921.1     17
 ORF   Nilaparvata lugens ANJ04656.1     17
 sucrase (Su1)   Nilaparvata lugens AEO89448.1
AGE93915.1
AGE93916.1
AGE93917.1
AGE93918.1
AGE93919.1
    17
 sucrase, partial (Su1) (fragment)   Nilaparvata muiri AGE93920.1     17
 α-amylase (fragment)   Ochlerotatus procax AFL90688.1     17
 α-amylase (fragment)   Ochlerotatus theobaldi AFL90691.1     17
 maltase (salivary)   Ochlerotatus triseriatus ACU30949.1 C6ZQU5   17
 α-amylase, partial (fragment)   Ochlerotatus vigilax AFN68795.1
AFN68784.1
AFN68785.1
AFN68786.1
AFN68790.1
AFN68791.1
AFN68798.1
AFN68803.1
AFN68805.1
AFN68814.1
AFN68819.1
AFN68826.1
AFN68827.1
AFN68830.1
    17
 α-amylase, partial (fragment)   Ochlerotatus vigilax AFN68836.1
AFN68782.1
AFN68783.1
AFN68789.1
AFN68794.1
AFN68796.1
AFN68797.1
AFN68800.1
AFN68810.1
AFN68813.1
AFN68815.1
AFN68816.1
AFN68820.1
AFN68828.1
AFN68831.1
AFN68832.1
AFN68839.1
AFN68840.1
AFN68843.1
AFN68846.1
    17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68822.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68837.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68809.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68781.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68801.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68838.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68788.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68824.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68793.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68787.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68799.1
AFN68792.1
    17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68818.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68834.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68812.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68825.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68817.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68804.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68842.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68829.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68821.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68811.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68802.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68806.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68807.1
AFN68808.1
AFN68835.1
    17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68823.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68833.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68841.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68844.1     17
 alpha amylase, partial (fragment)   Ochlerotatus vigilax AFN68845.1     17
 α-glucosidase   Periplaneta americana AIA09343.1     17
 ORF (fragment)   Phlebotomus perniciosus Spain ADL40395.1     17
 α-glucosidase (AgluI) (fragment)   Rhodnius prolixus ACI96031.1 B6V6H0   17
 alpha amylase, partial (fragment)   Rhynchophorus ferrugineus AMK48611.1     17
 α-glucosidase, partial (fragment)   Rhynchophorus ferrugineus AMK48651.1     17
 ORF   Riptortus pedestris BAN20159.1     17
 ORF   Riptortus pedestris BAN20192.1     17
 ORF   Riptortus pedestris BAN20149.1     17
 rBAT (Slc31)   Salmo salar ACN11390.1
ACN60293.1
C0HBH1
C0PUL0
  17
 sucrose hydrolase (ScSuh)   Samia ricini BAP18685.1     17
 salivary α-amylase (fragment)   Simulium guianense AEB96554.1     17
 salivary α-amylase (fragment)   Simulium nigrimanum ACZ28333.1 D1FQ78   17
 salivary α-amylase (fragment)   Simulium nigrimanum ACZ28334.1 D1FQ79   17
 ORF (fragment)   Simulium nigrimanum ACZ28335.1 D1FQ80   17
 salivary α-amylase (fragment)   Simulium vittatum ACH56864.1 B5M0Q0   17
 α-amylase, partial (fragment)   Spodoptera litura AGV76304.1     17
 sucrose hydrolase (TvSuh)   Trilocha varians BAP18684.1     17
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