Glycoside Hydrolase Family 13 / Subf 16

Activities in Sub Family	Trehalose synthase / maltose glucosylmutase (EC 5.4.99.16);
Mechanism	Retaining a
Clan	GH-H
3D Structure Status	( β / α ) ₈ barrel
Catalytic Nucleophile/Base	Asp (experimental)
Catalytic Proton Donor	Glu (experimental)
Note	New: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resources	CAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)	MEGAZYME; PROZOMIX;
Statistics	GenBank accession (2); Uniprot accession (23); PDB accession (11); 3D entries (5); cryst (0)

Summary

Download GH13_16 (8354) Taxonomic display Structure (5) Characterized (19)


Archaea
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D	Subf
trehalose synthase (PTO0069)	5.4.99.16		Picrophilus torridus DSM 9790	AAT42654.1 CBF79071.1	Q6L2Z7		16
Bacteria
Protein Name	EC#	Reference	Organism	GenBank	Uniprot	PDB/3D	Subf
trehalose synthase (TreS)	5.4.99.16		Actinoplanes sp. SN223/29	ABV26719.1	A8QX00		16
trehalose synthase (TreS;Deide_07350)	5.4.99.16	pubmed	Deinococcus deserti VCD115	ACO45593.1	C1D169		16
trehalose synthase (DrTS;DR2036)	5.4.99.16		Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539	AAF11586.1 AEJ36289.1 ANC70889.1 CAZ78703.1 CBF78903.1 NP_295759.1	I3NX86 Q9RST7	4TVU[A,B,C,D,E,F,G,H] 4WF7[A,B,C,D] 5GTV[A,B,C,D] 5GTW[A,B,C,D] 5YKB[A,B,C,D]	16
trehalose synthase (TreS)	5.4.99.16		Enterobacter hormaechei 7	ACI16355.1	B6E9W1		16
trehalose synthase (TreS)	5.4.99.16		Meiothermus ruber CBS-01	ACA35051.1	B1PK99		16
trehalose synthase (TreS;MtTS;Rv0126;RVBD_0126)	5.4.99.16	pubmed	Mycobacterium tuberculosis H37Rv	CAB09454.1 AFN47974.1 CCP42851.1 NP_214640.1	O07176 P9WQ19	4LXF[A,B]	16
trehalose synthase (TreS;MsTS;MSMEG_6515)	5.4.99.16		Mycolicibacterium smegmatis MC2 155	ABK71531.1 AFP42769.1 AIU11490.1	A0R6E0	3ZO9[A,B] 3ZOA[A,B] 5JY7[A,B,C,D,E,F,G,H]	16
trehalose synthase (TreS)	5.4.99.16		Paenarthrobacter aurescens CGMCC 1.1892	ACL80570.1	B8YM30		16
trehalose synthase (TreS)	5.4.99.16	doi	Pimelobacter sp. R48	BAA11303.1 CBF79254.1	P72235		16
trehalose synthase (TreS)	5.4.99.16		Propionibacterium freudenreichii subsp. shermanii NIZO B365	ABC88240.1 AAV63798.1	A1XGB1 A4FTT7		16
trehalose synthase (TreS;ROP_61000)	5.4.99.16	pubmed	Rhodococcus opacus B4	BAH54347.1	C1AZS6		16
SVEN_5096 (TreS)	5.4.99.16	pubmed	Streptomyces venezuelae ATCC 10712	CCA58382.1 QES01365.1	F2R410		16
trehalose synthase (TreS; TtTS; Tter_0330)	5.4.99.16	pubmed	Thermobaculum terrenum ATCC BAA-798	ACZ41252.1	D1CE96	5X7U[A]	16
trehalose synthase (TreS;Tfu_0584)	5.4.99.16		Thermobifida fusca YX	AAZ54622.1 CAZ78814.1 CBF79133.1	Q47SE5		16
trehalose synthase (TreS)	5.4.99.16		Thermus aquaticus ATCC 33923	BAA19934.1	O06458		16
trehalose synthase (TreS)	5.4.99.16		Thermus caldophilus GK24	AAD50660.3 AAD50660.1	Q9RA59		16
trehalose synthase (TTHA0478)	5.4.99.16		Thermus thermophilus HB8	BAD70301.1 AAW21753.1	Q5MCN4 Q5SL15		16
trehalose synthase (TreS;TtTS)	5.4.99.16	URL	Thermus thermophilus HJ6	ABW87308.1	A8WAD0		16
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