Glycoside Hydrolase Family 13 / Subf 10

Activities in Familyα-amylase (EC 3.2.1.1); pullulanase (EC 3.2.1.41); cyclomaltodextrin glucanotransferase (EC 2.4.1.19); cyclomaltodextrinase (EC 3.2.1.54); trehalose-6-phosphate hydrolase (EC 3.2.1.93); oligo-α-glucosidase (EC 3.2.1.10); maltogenic amylase (EC 3.2.1.133); neopullulanase (EC 3.2.1.135); α-glucosidase (EC 3.2.1.20); maltotetraose-forming α-amylase (EC 3.2.1.60); isoamylase (EC 3.2.1.68); glucodextranase (EC 3.2.1.70); maltohexaose-forming α-amylase (EC 3.2.1.98); maltotriose-forming α-amylase (EC 3.2.1.116); branching enzyme (EC 2.4.1.18); trehalose synthase (EC 5.4.99.16); 4-α-glucanotransferase (EC 2.4.1.25); maltopentaose-forming α-amylase (EC 3.2.1.-) ; amylosucrase (EC 2.4.1.4) ; sucrose phosphorylase (EC 2.4.1.7); malto-oligosyltrehalose trehalohydrolase (EC 3.2.1.141); isomaltulose synthase (EC 5.4.99.11); malto-oligosyltrehalose synthase (EC 5.4.99.15); amylo-α-1,6-glucosidase (EC 3.2.1.33); α-1,4-glucan: phosphate α-maltosyltransferase (EC 2.4.99.16); 6'-P-sucrose phosphorylase (EC 2.4.1.-); amino acid transporter
Activities in Sub Family
Mechanism Retaining
ClanGH-H
3D Structure Status( β / α ) 8
Catalytic Nucleophile/BaseAsp (experimental)
Catalytic Proton DonorGlu (experimental)
NoteNew: many members have been assigned to subfamilies as described by Stam et al. (2006) Protein Eng Des Sel. 19, 555-562 (PMID: 17085431)
External resourcesCAZypedia; EBI Protein of the Month; HOMSTRAD; PDB Molecule of the Month; PRINTS;
Commercial Enzyme Provider(s)MEGAZYME; PROZOMIX;
Statistics GenBank accession (2488); Uniprot accession (303); PDB accession (18); 3D entries (3); cryst (0)
All (2415) Archaea (35) Bacteria (2380) Structure (3) Characterized (15)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 maltooligosyltrehalose trehalohydrolase (TreZ;MTH) 3.2.1.141 Metallosphaera hakonensis JCM 8857 AAR18372.1 Q6SZP6   10
 α-amylase/maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.1
3.2.1.141
Sulfolobus acidocaldarius BAA11011.1
BAA11863.1
Q53641   10
 maltooligosyl trehalose trehalohydrolase (TreZ) 3.2.1.141 Sulfolobus shibatae AAF17553.1
AAM81589.1
Q9UWN9   10
 α-amylase / maltooligosyltrehalose trehalohydrolase (GTHase) 3.2.1.1
3.2.1.141
Sulfolobus solfataricus KM1 AAR46454.1
BAA11010.1
Q55088 1EH9[A]
1EHA[A]
3VGB[A]
3VGD[A]
3VGE[A]
3VGF[A]
3VGG[A]
3VGH[A]
10
 maltooligosyltrehalose trehalohydrolase (TreZ;MTHase;SSO2093;c06020) 3.2.1.141 Sulfolobus solfataricus P2 AAK42272.1
CAA69503.1
CAC23737.1
NP_343482.1
P95867   10
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3DSubf
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Actinoplanes sp. SN223/29 ABV26726.1 A8QX08   10
 malto-oligosyltrehalose trehalohydrolase (MTHase;TreZ) 3.2.1.141 Arthrobacter ramosus S34 BAB40766.1 Q9AJN6   10
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Arthrobacter sp. Q36 AAE13738.1
AAE13730.1
AAE15470.1
AAE15478.1
BAA09668.1
Q44316   10
 maltooligosyltrehalose trehalohydrolase (TreZ;BvMth) 3.2.1.141 Brevibacterium helvolum AAB95369.1 O52520   10
 maltooligosyltrehalose trehalohydrolase(TreZ;Cgl2125;cg2333) 3.2.1.141 Corynebacterium glutamicum ATCC 13032 BAB99519.1
ACK11454.1
CAC25671.1
CAD43537.1
CAD88152.1
CAF20463.1
CCH25265.1
NP_601327.2
Q8NNR1   10
 malto-oligosyltrehalose trehalohydrolase (DR0464) 3.2.1.141 Deinococcus radiodurans R1 AAF10042.1
ANC72786.1
NP_294187.1
Q9RX51 2BHU[A]
2BHY[A]
2BHZ[A]
2BXY[A]
2BXZ[A]
2BY0[A]
2BY1[A]
2BY2[A]
2BY3[A]
10
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Kocuria rosea QS412 AAY83363.1 Q4JQI8   10
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Nostoc flagelliforme ADM32915.1 E1ANS4   10
 maltooligosyltrehalose trehalohydrolase (TreZ) 3.2.1.141 Nostoc punctiforme IAM M-15 BAG85336.1 B6ZIU9   10
 Malto-oligosyltrehalose trehalohydrolase 3.2.1.141 Rhizobium sp. M-11 AAE13737.1
AAE13729.1
AAE15469.1
AAE15477.1
BAA11187.1
Q53238   10
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