Glycoside Hydrolase Family 134

Activities in Familyendo-β-1,4-mannanase (EC 3.2.1.78);
Mechanism inverting
NoteCreated after the work by Shimizu and collaborators. J. Biol. Chem. (2015). [ PMID:26385921 ]. Presents an inverting mechanism in what is a unique feature compared to all other b-mannanases [see Jin et al. ACS Cent. Sci (2016) doi:10.1021/acscentsci.6b00232 ]
External resourcesCAZypedia;
Statistics GenBank accession (138); Uniprot accession (0); PDB accession (3); 3D entries (1); cryst (0)
| 1 | 2 |
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 EGX54366.1   Arthrobotrys oligospora ATCC 24927 EGX54366.1    
 ACLA_044460   Aspergillus clavatus NRRL 1 EAW13726.1    
 ACLA_032970   Aspergillus clavatus NRRL 1 EAW08561.1    
 NFIA_023140   Aspergillus fischeri NRRL 181 EAW23603.1    
 AFLA70_56g003981   Aspergillus flavus AF70 KOC17749.1    
 AFLA70_465g000530   Aspergillus flavus AF70 KOC13974.1    
 AFLA70_20g004951   Aspergillus flavus AF70 KOC10525.1    
 AFLA_069880   Aspergillus flavus NRRL3357 EED50166.1    
 AFLA_023360 (fragment)   Aspergillus flavus NRRL3357 EED55065.1    
 AFUB_079280   Aspergillus fumigatus A1163 EDP49895.1    
 AFUA_1G01520   Aspergillus fumigatus Af293 EAL87863.2    
 BA78_7752   Aspergillus fumigatus var. RP-2014 niveus KEY76251.1    
 endo-β-1,4-mannanase (AN2710;ANID_02710) (Man134A) 3.2.1.78 Aspergillus nidulans FGSC A4 EAA63112.1    
 AN6833.2 (fragment)   Aspergillus nidulans FGSC A4 EAA58232.1    
 AN6951.2   Aspergillus nidulans FGSC A4 EAA57706.1    
 AN7638.2 (fragment)   Aspergillus nidulans FGSC A4 EAA61824.1    
 ANOM_007857   Aspergillus nomius NRRL 13137 KNG83759.1    
 ANOM_008649   Aspergillus nomius NRRL 13137 KNG82748.1    
 ANOM_008685   Aspergillus nomius NRRL 13137 KNG84541.1    
 Ao3042_06936   Aspergillus oryzae 3.042 EIT76902.1    
 AO090038000445   Aspergillus oryzae RIB40 BAE64233.1    
 AO090102000262 (fragment)   Aspergillus oryzae RIB40 BAE61341.1    
 AOR_1_744074   Aspergillus oryzae RIB40 XP_001825366.2    
 AOR_1_456134   Aspergillus oryzae RIB40 XP_001822474.2    
 AOR_1_2660154   Aspergillus oryzae RIB40 XP_003189654.1    
 P875_00010040   Aspergillus parasiticus SU-1 KJK65677.1    
 ATEG_04915   Aspergillus terreus NIH2624 EAU35362.1    
 AUD_8993   Aspergillus udagawae IFM 46973 GAO90033.1    
 BOTBODRAFT_34959   Botryobasidium botryosum FD-172 SS1 KDQ11869.1    
 W97_07402   Coniosporium apollinis CBS 100218 EON67905.1    
 AW171_hschr73998   Eremothecium sinecaudum ATCC 58844 AMD21995.1    
 FAVG1_02222   Fusarium avenaceum Fa05001 KIL93662.1    
 FAVG1_12643   Fusarium avenaceum Fa05001 KIL84067.1    
 FFUJ_14310   Fusarium fujikuroi IMI 58289 CCT69197.1    
 LW93_14999   Fusarium fujikuroi KSU X-10626 KLO83329.1    
 FOC1_g10001987   Fusarium oxysporum f. sp. cubense race 1 ENH75837.1    
 FOC1_g10000068   Fusarium oxysporum f. sp. cubense race 1 ENH63549.1    
 FOC4_g10008822   Fusarium oxysporum f. sp. cubense race 4 EMT70377.1    
 FOWG_17427   Fusarium oxysporum f. sp. lycopersici MN25 EWZ78279.1    
 FOVG_16986   Fusarium oxysporum f. sp. pisi HDV247 EXA31749.1    
 FOQG_16189   Fusarium oxysporum f. sp. raphani 54005 EXK79170.1    
 FOTG_18401   Fusarium oxysporum f. sp. vasinfectum 25433 EXM13141.1    
 FOXB_07366   Fusarium oxysporum Fo5176 EGU82120.1    
 FOXB_07826   Fusarium oxysporum Fo5176 EGU81657.1    
 FOYG_09022   Fusarium oxysporum FOSC 3-a EWY92126.1    
 FVEG_09417 (fragment)   Fusarium verticillioides 7600 EWG50090.1    
 GALMADRAFT_213725   Galerina marginata CBS 339.88 KDR71904.1    
 Lema_p106070.1   Leptosphaeria maculans JN3 v23.1.3 CBX97476.1    
 MAM1_0057c03638   Mucor ambiguus NBRC 6742 GAN04178.1    
 MAM1_0800c11253   Mucor ambiguus NBRC 6742 GAN11672.1    
 HMPREF1544_07588   Mucor circinelloides f. circinelloides 1006PhL EPB85595.1    
 NECHADRAFT_89135   Nectria haematococca mpVI 77-13-4 EEU33800.1    
 PMG11_01414   Penicillium brasilianum CEJ55139.1    
 PCAMFM013_S033g000022   Penicillium camemberti FM013 CRL29102.1    
 PCAMFM013_S018g000024   Penicillium camemberti FM013 CRL26331.1    
 PCAMFM013_S034g000067   Penicillium camemberti FM013 CRL29269.1    
 PCAMFM013_S003g000055   Penicillium camemberti FM013 CRL19264.1    
 PEXP_092440   Penicillium expansum d1 KGO43875.1    
 PEXP_094870   Penicillium expansum d1 KGO43585.1    
 PEXP_069390   Penicillium expansum d1 KGO46769.1    
 PEXP_069380   Penicillium expansum d1 KGO46768.1    
 PEXP_005260   Penicillium expansum d1 KGO36727.1    
 ACN38_g7896   Penicillium nordicum DAOM 185683 KOS41266.1    
 ACN38_g602   Penicillium nordicum DAOM 185683 KOS48391.1    
 ACN38_g1620   Penicillium nordicum DAOM 185683 KOS47468.1    
 ACN38_g5388   Penicillium nordicum DAOM 185683 KOS43693.1    
 Pc21g05480   Penicillium rubens Wisconsin 54-1255 CAP95445.1    
 Pc12g13760   Penicillium rubens Wisconsin 54-1255 CAP81003.1    
 Pc16g03640   Penicillium rubens Wisconsin 54-1255 CAP93034.1    
 U727_00431140191   Penicillium solitum RS1 KJJ26098.1    
 U727_0043436001   Penicillium solitum RS1 KJJ09669.1    
 U727_00433592421   Penicillium solitum RS1 KJJ15877.1    
 U727_0043105021   Penicillium solitum RS1 KJJ26324.1    
 U727_0043109051 (fragment)   Penicillium solitum RS1 KJJ26202.1    
 V499_06905   Pseudogymnoascus sp. VKM F-103 KFY72999.1    
 V499_01291   Pseudogymnoascus sp. VKM F-103 KFY79750.1    
 V490_06010   Pseudogymnoascus sp. VKM F-3557 KFX91241.1    
 V491_03355   Pseudogymnoascus sp. VKM F-3775 KFY20876.1    
 V491_05769   Pseudogymnoascus sp. VKM F-3775 KFY15132.1    
 V491_00893 (fragment)   Pseudogymnoascus sp. VKM F-3775 KFY27465.1    
 O988_05594   Pseudogymnoascus sp. VKM F-3808 KFX95858.1    
 V492_05467   Pseudogymnoascus sp. VKM F-4246 KFY09542.1    
 V492_06650   Pseudogymnoascus sp. VKM F-4246 KFY07977.1    
 V493_05084   Pseudogymnoascus sp. VKM F-4281 (FW-2241) KFY24696.1    
 V495_06073   Pseudogymnoascus sp. VKM F-4514 (FW-929) KFY39220.1    
 V496_00343   Pseudogymnoascus sp. VKM F-4515 (FW-2607) KFY69341.1    
 V496_07542   Pseudogymnoascus sp. VKM F-4515 (FW-2607) KFY53482.1    
 V498_03884   Pseudogymnoascus sp. VKM F-4517 (FW-2822) KFY94407.1    
 V498_07457   Pseudogymnoascus sp. VKM F-4517 (FW-2822) KFY86580.1    
 V500_08829   Pseudogymnoascus sp. VKM F-4518 (FW-2643) KFY84966.1    
 V500_02850   Pseudogymnoascus sp. VKM F-4518 (FW-2643) KFY95297.1    
 V501_00483   Pseudogymnoascus sp. VKM F-4519 (FW-2642) KFZ19809.1    
 V501_01477   Pseudogymnoascus sp. VKM F-4519 (FW-2642) KFZ17922.1    
 V502_10314   Pseudogymnoascus sp. VKM F-4520 (FW-2644) KFZ04219.1    
 V502_11421   Pseudogymnoascus sp. VKM F-4520 (FW-2644) KFZ02892.1    
 PCON_02213   Pyronema omphalodes CBS 100304 CBS100304 CCX33950.1    
 RO3G_11308   Rhizopus delemar RA 99-880 EIE86597.1    
 RO3G_00915   Rhizopus delemar RA 99-880 EIE76211.1    
 RO3G_11298   Rhizopus delemar RA 99-880 EIE86587.1    
 RO3G_01113   Rhizopus delemar RA 99-880 EIE76409.1    
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