Glycoside Hydrolase Family 130

Activities in Familyβ-1,4-mannosylglucose phosphorylase (EC 2.4.1.281); β-1,4-mannooligosaccharide phosphorylase (EC 2.4.1.319); β-1,4-mannosyl-N-acetyl-glucosamine phosphorylase (EC 2.4.1.320); β-1,2-mannobiose phosphorylase (EC 2.4.1.-); β-1,2-oligomannan phosphorylase (EC 2.4.1.-); β-1,2-mannosidase (EC 3.2.1.-)
Mechanism inverting
3D Structure Status5-fold β-propeller
NoteCreated after Senoura et al. (2011) BBRC 408, 701-706 [PMID: 21539815]
External resourcesCAZypedia;
Statistics GenBank accession (1432); Uniprot accession (32); PDB accession (22); 3D entries (11); cryst (0)
All (1400) Archaea (107) Bacteria (1275) Eukaryota (10) unclassified (8) Structure (11) Characterized (14)
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-1,4-mannosylglucose phosphorylase (MGP;BF0772) 2.4.1.281 Bacteroides fragilis NCTC 9343 CAH06518.1 Q5LH68 3WAS[A,B]
3WAT[A,B]
3WAU[A,B]
4KMI[A,B]
 β-1,2-mannosidase (BACOVA_03624) 3.2.1.- Bacteroides ovatus ATCC 8483 EDO10988.1   3QC2[A,B]
 β-1,4-mannosyl-N-acetyl-glucosamine phosphorylase (BT1033) 2.4.1.320 Bacteroides thetaiotaomicron VPI-5482 AAO76140.1
NP_809946.1
Q8A8Y4  
 β-1,2-mannosidase (BT3780;BT_3780) 3.2.1.- Bacteroides thetaiotaomicron VPI-5482 AAO78885.1   5A7V[A,B]
 CalpoDRAFT_0075 2.4.1.- Caldanaerobius polysaccharolyticus ATCC BAA-17 WP_026485574.1    
 CalpoDRAFT_1209 2.4.1.- Caldanaerobius polysaccharolyticus ATCC BAA-17 WP_026486530.1    
 β-1,4-mannosylglucose phosphorylase (Unk1) 2.4.1.281 Cellvibrio mixtus AAS19693.1 Q6QT44  
 β-1,2-mannosidase (Dfer_3176) 3.2.1.- Dyadobacter fermentans DSM 18053 ACT94389.1    
 β-1,2-mannobiose phosphorylase (Lin0857) 2.4.1.- Listeria innocua Clip11262 CAC96089.1
NP_470199.1
Q92DF6 5B0P[A,B]
5B0Q[A,B]
5B0R[A,B]
5B0S[A,B]
 β-1,4-mannosylglucose phosphorylase (RaMP1;RaMGP;Rumal_0852) 2.4.1.281 Ruminococcus albus 7 = DSM 20455 ADU21379.1 E6UIS7 5AY9[A]
5AYC[A]
 β-1,4-mannooligosaccharide phosphorylase (MOP;RaMP2;Rumal_0099) 2.4.1.319 Ruminococcus albus 7 = DSM 20455 ADU20661.1 E6UBR9 5AYD[A,B,C,D,E,F]
5AYE[A,B,C,D,E,F]
 β-1,2-mannobiose phosphorylase (Teth514_1789) 2.4.1.- Thermoanaerobacter sp. X514 ABY93074.1 B0K2C3  
 β-1,2-oligomannan phosphorylase (Teth514_1788) 2.4.1.- Thermoanaerobacter sp. X514 ABY93073.1 B0K2C2  
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 β-1,4-mannopyranosyl-[N-glycan] phosphorylase / β-1,4-mannopyranosyl-chitobiose phosphorylase (UhgbMP;Uhgb_MP) 2.4.1.319
2.4.1.320
uncultured organism ADD61463.1   4UDG[A,B,C,D,E,F]
4UDI[A,B,C,D,E,F]
4UDJ[A,B,C,D,E,F]
4UDK[A,B,C,D,E,F]
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