Glycoside Hydrolase Family 12

Activities in Familyendoglucanase (EC 3.2.1.4); xyloglucan hydrolase (EC 3.2.1.151); β-1,3-1,4-glucanase (EC 3.2.1.73); xyloglucan endotransglycosylase (EC 2.4.1.207)
Mechanism Retaining
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (953); Uniprot accession (212); PDB accession (48); 3D entries (17); cryst (1)
All (762) Archaea (81) Bacteria (532) Eukaryota (148) unclassified (1) Structure (17 - 1 cryst) Characterized (68)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 T2812B_05955   Thermotoga sp. 2812B AIY86724.1    
 T2812B_05935 (fragment)   Thermotoga sp. 2812B AIY86720.1    
 CELL2_06605   Thermotoga sp. Cell2 AIY88589.1    
 CELL2_06600   Thermotoga sp. Cell2 AIY88588.1    
 TRQ2_1187   Thermotoga sp. RQ2 ACB09531.1 B1LB33  
 TRQ2_1188   Thermotoga sp. RQ2 ACB09532.1 B1LB34  
 TRQ7_07010   Thermotoga sp. RQ7 AJG41199.1    
 TRQ7_07005   Thermotoga sp. RQ7 AJG41198.1    
 GH12 protein   uncultured Bacillus sp. ALA15661.1    
 endoglucanase (RSC-EG1)   uncultured bacterium AFD36891.1    
 cellulase (Lc-CelA) 3.2.1.4 uncultured bacterium AHL27894.1   3WX5[A,B]
 cellulase (Lc-CelD) 3.2.1.4 uncultured bacterium AHL27897.1    
 cellulase (Lc-CelE) 3.2.1.4 uncultured bacterium AHL27898.1    
 Cel12E   unidentified prokaryotic organism CRL09147.1    
 CMV30_09020   Verrucomicrobia bacterium HZ-65 ATC64082.1    
 VAB18032_10320   Verrucosispora maris AB-18-032 AEB43182.1    
 BSQ33_03960   Vibrio gazogenes ATCC 43942 ASA54962.1    
 XALc_0865   Xanthomonas albilineans GPE PC73 CBA15383.1    
 AKJ12_14810   Xanthomonas arboricola pv. juglandis Xaj 417 AKU50917.1    
 XAC3507 + XAC3506 (CelS) (two fragments)   Xanthomonas axonopodis pv. citri str. 306 AAM38349.1
AAM38350.1
NP_643813.1
NP_643814.1
   
 XACM_3403 (CelS)   Xanthomonas axonopodis pv. citrumelo F1 AEO43650.1    
 XB05_12325   Xanthomonas campestris 17 AKC79434.1    
 AAW18_16680   Xanthomonas campestris pv. campestris 17 ALE69939.1    
 AAW18_16675   Xanthomonas campestris pv. campestris 17 ALE69938.1    
 AEA01_03880   Xanthomonas campestris pv. campestris 4013 AKS19163.1    
 AEA01_03885   Xanthomonas campestris pv. campestris 4013 AKS19164.1    
 AEA00_03850   Xanthomonas campestris pv. campestris ICMP 21080 AKS15134.1    
 AEA00_03845   Xanthomonas campestris pv. campestris ICMP 21080 AKS15133.1    
 XC_0783   Xanthomonas campestris pv. campestris str. 8004 AAY47861.1 Q4UYL2  
 XC_0784   Xanthomonas campestris pv. campestris str. 8004 AAY47862.1 Q4UYL1  
 XCC3380   Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42650.1
NP_638726.1
Q8P5G1  
 CelS   Xanthomonas campestris pv. campestris str. ATCC 33913 AAM42651.1
NP_638727.1
Q8P5G0  
 xcc-b100_0818   Xanthomonas campestris pv. campestris str. B100 CAP50159.1 Q8P5G0  
 xcc-b100_0819   Xanthomonas campestris pv. campestris str. B100 CAP50160.1 Q8P5G1  
 XCR_3716   Xanthomonas campestris pv. raphani 756C AEL08576.1    
 XCR_3717   Xanthomonas campestris pv. raphani 756C AEL08577.1    
 XCV3634 (CelS)   Xanthomonas campestris pv. vesicatoria str. 85-10 CAJ25365.1
AOY66992.1
Q3BPE8  
 XcfCFBP4885P_14440   Xanthomonas citri pv. phaseoli var. fuscans CFBP4885 ATS64467.1    
 XcfCFBP6165P_11115   Xanthomonas citri pv. phaseoli var. fuscans CFBP6165 ATS67962.1    
 XcfCFBP6166P_01745   Xanthomonas citri pv. phaseoli var. fuscans CFBP6166 ATS70471.1    
 XcfCFBP6167P_02445   Xanthomonas citri pv. phaseoli var. fuscans CFBP6167 ATS87344.1    
 XcfCFBP6975P_16100   Xanthomonas citri pv. phaseoli var. fuscans CFBP6975 ATS77054.1    
 XcfCFBP6988P_20380   Xanthomonas citri pv. phaseoli var. fuscans CFBP6988R ATS40190.1    
 XcfCFBP6989P_00110   Xanthomonas citri pv. phaseoli var. fuscans CFBP6989 ATS40995.1    
 XcfCFBP6990P_17250   Xanthomonas citri pv. phaseoli var. fuscans CFBP6990 ATS48198.1    
 XcfCFBP6991P_16980   Xanthomonas citri pv. phaseoli var. fuscans CFBP6991 ATS85421.1    
 XcfCFBP7767P_05585   Xanthomonas citri pv. phaseoli var. fuscans CFBP7767 ATS79446.1    
 XcvCFBP7111P_05435   Xanthomonas citri pv. vignicola CFBP7111 ASK91014.1    
 XcvCFBP7113P_17950   Xanthomonas citri pv. vignicola CFBP7113 ASL01977.1    
 J152_03687 (fragment)   Xanthomonas citri subsp. citri 5208 AJZ41319.1    
 J152_03686 (fragment)   Xanthomonas citri subsp. citri 5208 AJZ41318.1    
 J151_03694 (fragment)   Xanthomonas citri subsp. citri A306 AJD70100.1    
 J151_03693 (fragment)   Xanthomonas citri subsp. citri A306 AJD70099.1    
 XCAW_04205 (fragment)   Xanthomonas citri subsp. citri Aw12879 AGI09970.1    
 XCAW_04204 (fragment)   Xanthomonas citri subsp. citri Aw12879 AGI09969.1    
 J165_04179 (fragment)   Xanthomonas citri subsp. citri AW13 AJZ46263.1    
 J165_04180 (fragment)   Xanthomonas citri subsp. citri AW13 AJZ46264.1    
 J166_04184 (fragment)   Xanthomonas citri subsp. citri AW14 AJZ50883.1    
 J166_04185 (fragment)   Xanthomonas citri subsp. citri AW14 AJZ50884.1    
 J167_04186 (fragment)   Xanthomonas citri subsp. citri AW15 AJZ55505.1    
 J167_04185 (fragment)   Xanthomonas citri subsp. citri AW15 AJZ55504.1    
 J168_04180 (fragment)   Xanthomonas citri subsp. citri AW16 AJZ68294.1    
 J168_04181 (fragment)   Xanthomonas citri subsp. citri AW16 AJZ68295.1    
 J170_03684 (fragment)   Xanthomonas citri subsp. citri BL18 AJZ36851.1    
 J170_03685 (fragment)   Xanthomonas citri subsp. citri BL18 AJZ36852.1    
 J171_03686 (fragment)   Xanthomonas citri subsp. citri FB19 AJZ32388.1    
 J171_03685 (fragment)   Xanthomonas citri subsp. citri FB19 AJZ32387.1    
 J154_03671 (fragment)   Xanthomonas citri subsp. citri gd2 AJZ27949.1    
 J154_03670 (fragment)   Xanthomonas citri subsp. citri gd2 AJZ27948.1    
 J155_03673 (fragment)   Xanthomonas citri subsp. citri gd3 AJZ23525.1    
 J155_03672 (fragment)   Xanthomonas citri subsp. citri gd3 AJZ23524.1    
 J156_03668 (fragment)   Xanthomonas citri subsp. citri jx4 AJZ19096.1    
 J156_03669 (fragment)   Xanthomonas citri subsp. citri jx4 AJZ19097.1    
 J157_03673 (fragment)   Xanthomonas citri subsp. citri jx5 AJZ14672.1    
 J157_03674 (fragment)   Xanthomonas citri subsp. citri jx5 AJZ14673.1    
 J172_03683 (fragment)   Xanthomonas citri subsp. citri mf20 AJZ10219.1    
 J172_03684 (fragment)   Xanthomonas citri subsp. citri mf20 AJZ10220.1    
 J162_03673 (fragment)   Xanthomonas citri subsp. citri MN10 AJZ05781.1    
 J162_03672 (fragment)   Xanthomonas citri subsp. citri MN10 AJZ05780.1    
 J163_03667 (fragment)   Xanthomonas citri subsp. citri MN11 AJZ01352.1    
 J163_03668 (fragment)   Xanthomonas citri subsp. citri MN11 AJZ01353.1    
 J164_03668 (fragment)   Xanthomonas citri subsp. citri MN12 AJY96928.1    
 J164_03669 (fragment)   Xanthomonas citri subsp. citri MN12 AJY96929.1    
 J169_03691 (fragment)   Xanthomonas citri subsp. citri NT17 AJY92480.1    
 J169_03690 (fragment)   Xanthomonas citri subsp. citri NT17 AJY92479.1    
 J158_03670 (fragment)   Xanthomonas citri subsp. citri UI6 AJY88035.1    
 J158_03671 (fragment)   Xanthomonas citri subsp. citri UI6 AJY88036.1    
 BER92_03010   Xanthomonas fragariae AOD13876.1    
 BER93_03015   Xanthomonas fragariae AOD17268.1    
 NBC2815_03389 (fragment)   Xanthomonas fragariae SMQ96709.1    
 PD5205_00624   Xanthomonas fragariae SMR01944.1    
 PD885_03385 (CelS)   Xanthomonas fragariae SMR00606.1    
 AC028_02875   Xanthomonas fuscans subsp. aurantifolii 1566 AMV05895.1    
 TP37_03830 (fragment)   Xanthomonas fuscans subsp. aurantifolii FDC 1559 AMV00707.1    
 TP50_04320 (fragment)   Xanthomonas fuscans subsp. aurantifolii FDC 1609 AMV05030.1    
 CKU38_03559   Xanthomonas fuscans subsp. fuscans FX01 ATB59929.1    
 XFF4834R_chr11400   Xanthomonas fuscans subsp. fuscans str. 4834-R CDF60739.1    
 BI317_19730   Xanthomonas gardneri ICMP 7383 APP86053.1    
 BI317_19725   Xanthomonas gardneri ICMP 7383 APP87086.1    
 BJD10_20980   Xanthomonas gardneri JS749-3 APP82498.1    
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