Glycoside Hydrolase Family 12

Activities in Familyendoglucanase (EC 3.2.1.4); xyloglucan hydrolase (EC 3.2.1.151); β-1,3-1,4-glucanase (EC 3.2.1.73); xyloglucan endotransglycosylase (EC 2.4.1.207)
Mechanism Retaining
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (1030); Uniprot accession (212); PDB accession (48); 3D entries (17); cryst (1)
All (838) Archaea (88) Bacteria (586) Eukaryota (163) unclassified (1) Structure (17 - 1 cryst) Characterized (69)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 cellulase A (CelA) (Cel12A) 3.2.1.4 Rhodothermus marinus ITI378 AAB65594.1
AAR63650.1
AAR67703.1
ABJ29234.1
ACP76253.1
O33897 1H0B[A,B]
2BW8[A,B]
2BWA[A,B]
2BWC[A,B]
3B7M[A,B,C,D]
 Rhom172_1176   Rhodothermus marinus SG0.5JP17-172 AEN73104.1    
 Sare_4899   Salinispora arenicola CNS-205 ABW00649.1 A8LVG0  
 Strop_4424   Salinispora tropica CNB-440 ABP56852.1 A4XD45  
 SARB121R_1 (fragment)   Sinorhizobium arboris LMG14919; HAMBI1552 ABD74851.1 D1CSP7  
 AOX55_00004326   Sinorhizobium fredii CCBAU 25509 AWM29762.1    
 AB395_00004297 (fragment)   Sinorhizobium fredii CCBAU 45436 AWI61822.1    
 SF83666_a40330 (fragment)   Sinorhizobium fredii CCBAU 83666 ASY73621.1    
 SFHH103_04355   Sinorhizobium fredii HH103 CCE98835.1    
 type III effector NopAA   Sinorhizobium fredii USDA207 AGH09914.1    
 type III effector NopAA   Sinorhizobium fredii USDA257 AGH09926.1    
 ORF51   Sinorhizobium meliloti ABA56022.1 Q1WLH8  
 SMRU11_01365   Sinorhizobium meliloti RU11/001 ARS66095.1    
 ORF Orf70 (fragment)   Sinorhizobium meliloti SM11 ABN47076.1 A4KVH5  
 glycosyl hydrolase   Sinorhizobium meliloti USDA1963 (plasmid pHRB800) AJT61687.1    
 SS05631_a48680 (fragment)   Sinorhizobium sp. CCBAU 05631 ASY61251.1    
 SOCE26_078500   Sorangium cellulosum So ce26 AUX46344.1    
 sce5731   Sorangium cellulosum So ce56 CAN95894.1 A9G7R2  
 SCE1572_06285   Sorangium cellulosum So0157-2 AGP34139.1    
 C1T17_00525   Sphingobium sp. SCG-1 AUW56788.1    
 STHERM_c04060   Spirochaeta thermophila DSM 6192 ADN01378.1 E0RPR4  
 STHERM_c20650 3.2.1.4 Spirochaeta thermophila DSM 6192 ADN02999.1 E0RQU3  
 Spith_0373 (StCBM64C)   Spirochaeta thermophila DSM 6578 AEJ60658.1    
 Spith_2106   Spirochaeta thermophila DSM 6578 AEJ62362.1    
 DMT42_28825   Streptomyces actuosus ATCC 25421 AWT45897.1    
 DMT42_28340   Streptomyces actuosus ATCC 25421 AWT45815.1    
 SAM23877_5412   Streptomyces ambofaciens ATCC 23877 AKZ58457.1    
 SAM23877_1270   Streptomyces ambofaciens ATCC 23877 AKZ54319.1    
 SAML1173   Streptomyces ambofaciens ATCC 23877 CAJ90159.1 A3KKC3  
 SAM40697_1111   Streptomyces ambofaciens DSM 40697 ANB05071.1    
 SAM40697_4908   Streptomyces ambofaciens DSM 40697 ANB08865.1    
 cellulase (Cel12B)   Streptomyces argenteolus M178 BAP19008.1    
 BV401_31930   Streptomyces autolyticus CGMCC0516 AQA14333.1    
 SAV2571   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70282.1
NP_823747.1
   
 SAV555 (CelA1)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC68265.1
NP_821730.1
   
 SAV2568 (CelA4)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70279.1
NP_823744.1
   
 SBI_02150   Streptomyces bingchenggensis BCW-1 ADI05271.1 D7BT56  
 SBI_03420   Streptomyces bingchenggensis BCW-1 ADI06541.1 D7CAI4  
 SBI_09972   Streptomyces bingchenggensis BCW-1 ADI13090.1 D7CF74  
 SCO1187 (CelB;SCG11A.18)   Streptomyces coelicolor A3(2) CAB61599.1
AHA82090.1
NP_625477.1
Q9RJY3  
 SCO5691 or SC5H4.15   Streptomyces coelicolor A3(2) CAB91127.1
AHA82092.1
NP_629819.1
Q9KYS4  
 TU94_24000   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04081.1    
 TU94_04665   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP00870.1    
 BN159_2113 (Cela1)   Streptomyces davaonensis JCM 4913 CCK26492.1    
 SGLAU_26650   Streptomyces glaucescens GLA.O AIS01268.1    
 SGLAU_24490   Streptomyces glaucescens GLA.O AIS00840.1    
 AVL59_24080   Streptomyces griseochromogenes ATCC 14511 ANP52219.1    
 endo-β-1,4-glucanase (CelA2;Cel2) 3.2.1.4 Streptomyces halstedii JM8 AAC45429.1 O08468  
 SHJG_1894   Streptomyces hygroscopicus subsp. jinggangensis 5008 AEY87169.1    
 SHJGH_1659   Streptomyces hygroscopicus subsp. jinggangensis TL01 AGF61325.1    
 SHL15_0383   Streptomyces hygroscopicus subsp. limoneus KCTC 1717 ALO91588.1    
 SHXM_07212   Streptomyces hygroscopicus XM201 AQW53749.1    
 ABB07_10530   Streptomyces incarnatus NRRL 8089 AKJ10438.1    
 SIRAN3033   Streptomyces iranensis CDR06119.1    
 SLA_6235   Streptomyces laurentii ATCC 31255 BAU87104.1    
 Sle_19910   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR61452.1    
 Sle_59080   Streptomyces leeuwenhoekii C34 (= DSM 42122 = NRRL B-24963) CQR65364.1    
 SLINC_6733   Streptomyces lincolnensis NRRL 2936 ANS68957.1    
 SLINC_6107   Streptomyces lincolnensis NRRL 2936 ANS68331.1    
 SLINC_8275   Streptomyces lincolnensis NRRL 2936 ANS70499.1    
 SLINC_0625   Streptomyces lincolnensis NRRL 2936 ANS62849.1    
 endo-β-1,4-glucanase (CelB;CelB2;EGI) 3.2.1.4 Streptomyces lividans 1326 AAB71950.1
AAR63649.1
AAR67702.1
ABH87634.1
ABJ29233.1
ACP76252.1
Q54331 1NLR[A]
2NLR[A]
 cellulase (11AG8) 3.2.1.4 Streptomyces lividans TK23 AAQ31831.1
ABH87633.1
   
 SLIV_31860   Streptomyces lividans TK24 AIJ17260.1    
 SLIV_10170   Streptomyces lividans TK24 AIJ13034.1    
 SMALA_5611   Streptomyces malaysiensis DSM 4137 ATL85841.1    
 SMALA_8047   Streptomyces malaysiensis DSM 4137 ATL88257.1    
 SNOD_25355   Streptomyces nodosus ATCC 14899 AJE42988.1    
 SNOD_24165   Streptomyces nodosus ATCC 14899 AJE42792.1    
 B1H29_10270   Streptomyces pactum ACT12 AQS67261.1    
 B1H29_31990   Streptomyces pactum ACT12 AQS70901.1    
 Spa2297_04285   Streptomyces parvulus 2297 ANJ06270.1    
 Sfla_6354   Streptomyces pratensis ATCC 33331 ADW07712.1 C9N590  
 Sfla_0771   Streptomyces pratensis ATCC 33331 ADW02233.1 C9NF61  
 SPRI_6750   Streptomyces pristinaespiralis HCCB 10218 ALC25056.1    
 SPRI_6625   Streptomyces pristinaespiralis HCCB 10218 ALC24931.1    
 BFF78_11660   Streptomyces puniciscabiei TW1S1 AOR31621.1    
 M271_15500   Streptomyces rapamycinicus NRRL 5491 AGP54676.1    
 TUE45_06190 (CelS)   Streptomyces reticuli CUW31447.1    
 TUE45_pSRTUE45c_0481 (CeX)   Streptomyces reticuli CUW33113.1    
 endo-β-1,4-glucanase S (EglS) 3.2.1.4 Streptomyces rochei A2 CAA52139.1 Q59963  
 SCAB_5981 (CelB)   Streptomyces scabiei 87.22 CBG67793.1 C9YVP5  
 SCAB_25571   Streptomyces scabiei 87.22 CBG69663.1 C9Z271  
 SCAB_90081   Streptomyces scabiei 87.22 CBG75942.1 C9Z9L5  
 CGL27_33255   Streptomyces sp. 11-1-2 ASQ97258.1    
 cellulase 12A (Cel12A) 3.2.1.4 Streptomyces sp. 11AG8 AAF91283.1
AAE59731.1
AAQ25310.1
AAQ31830.1
AAR63648.1
AAR67701.1
ACP76251.1
Q9KIH1 1OA4[A]
 SAMN05428941_5778   Streptomyces sp. 2114.2 SDT76171.1    
 SAMN05428941_1220   Streptomyces sp. 2114.2 SDS81576.1    
 SAMN05444521_2491   Streptomyces sp. 3214.6 SHH90108.1    
 DC008_26015   Streptomyces sp. 452 AWE54793.1    
 ASR50_33355   Streptomyces sp. 4F ALV53826.1    
 ASR50_25700   Streptomyces sp. 4F ALV52474.1    
 GZL_09191 (fragment)   Streptomyces sp. 769 AJC61712.1    
 glycosyl hydrolase family 5, partial (fragment)   Streptomyces sp. AGERI-TA1 BBE15447.1    
 C2142_14235   Streptomyces sp. CB01881 AUY49888.1    
 NI25_10825   Streptomyces sp. CCM_MD2014 AIV33924.1    
 NI25_33295   Streptomyces sp. CCM_MD2014 AIV37792.1    
 AS200_04800   Streptomyces sp. CdTB01 ALV31448.1    
 AS200_13735   Streptomyces sp. CdTB01 ALV32999.1    
 CAC01_14350   Streptomyces sp. CLI2509 CLI2905 ASY33705.1    
Top


Last update: 2018-07-09 © Copyright 1998-2018
AFMB - CNRS - Université d'Aix-Marseille