Glycoside Hydrolase Family 12

Activities in FamilyXyloglucan-specific endo-β-1,4-glucanase / endo-xyloglucanase (EC 3.2.1.151);
Endo-β-1,4-glucanase (EC 3.2.1.4);
Lichenase / endo-β-1,3-1,4-glucanase (EC 3.2.1.73);
Mechanism Retaining e
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (2916); Uniprot accession (90); PDB accession (61); 3D entries (23); cryst (1)
| 1 | ... | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | ... | 21 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Spith_0373 (StCBM64C)   Spirochaeta thermophila DSM 6578 AEJ60658.1    
 Spith_2106   Spirochaeta thermophila DSM 6578 AEJ62362.1    
 GXP74_18930   Streptacidiphilus sp. P02-A3a QMU73907.1    
 GXW83_13815   Streptacidiphilus sp. PB12-B1b QMU76662.1    
 DMT42_28825   Streptomyces actuosus ATCC 25421 AWT45897.1    
 DMT42_28340   Streptomyces actuosus ATCC 25421 AWT45815.1    
 K1J60_12365   Streptomyces akebiae MG28 QYX77212.1    
 K1J60_01285   Streptomyces akebiae MG28 QYX75328.1    
 K1J60_12420   Streptomyces akebiae MG28 QYX77221.1    
 SAM23877_5412   Streptomyces ambofaciens ATCC 23877 AKZ58457.1    
 SAM23877_1270   Streptomyces ambofaciens ATCC 23877 AKZ54319.1    
 SAML1173   Streptomyces ambofaciens ATCC 23877 CAJ90159.1    
 SAM40697_1111   Streptomyces ambofaciens DSM 40697 ANB05071.1    
 SAM40697_4908   Streptomyces ambofaciens DSM 40697 ANB08865.1    
 HCX60_28320   Streptomyces antibioticus DSM 41481 QIT46951.1    
 QR300_13345   Streptomyces antimycoticus FIM95-F1 WJD96887.1    
 cellulase (Cel12B)   Streptomyces argenteolus M178 BAP19008.1    
 HKX69_33345   Streptomyces argyrophyllae Jing01 QJS13785.1    
 DVA86_16415   Streptomyces armeniacus ATCC 15676 AXK34006.1    
 G9272_07370   Streptomyces asoensis H2S5 QJT00126.1    
 G9272_32685   Streptomyces asoensis H2S5 QJT04469.1    
 CD934_00925   Streptomyces asterosporus DSM 41452 QDI67398.1    
 CD934_08620   Streptomyces asterosporus DSM 41452 QDI68742.1    
 O1Q96_26575   Streptomyces aurantiacus Qhu-M197 WAU82935.1    
 O1Q96_35655   Streptomyces aurantiacus Qhu-M197 WAU84564.1    
 G3H79_39915   Streptomyces aureoverticillatus HN6 QIB48335.1    
 G3H79_37630   Streptomyces aureoverticillatus HN6 QIB47938.1    
 BV401_31930   Streptomyces autolyticus CGMCC0516 AQA14333.1    
 SAV2571   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70282.1
NP_823747.1
   
 SAV555 (CelA1)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC68265.1
NP_821730.1
   
 SAV2568 (CelA4)   Streptomyces avermitilis MA-4680 = NBRC 14893 BAC70279.1
NP_823744.1
   
 SAVMC3_29980   Streptomyces avermitilis MC3 BBJ50369.1    
 SAVMC3_30010   Streptomyces avermitilis MC3 BBJ50372.1    
 SAVMC3_07100   Streptomyces avermitilis MC3 BBJ48081.1    
 SBI_02150   Streptomyces bingchenggensis BCW-1 ADI05271.1    
 SBI_03420   Streptomyces bingchenggensis BCW-1 ADI06541.1    
 SBI_09972   Streptomyces bingchenggensis BCW-1 ADI13090.1    
 EJC51_34590   Streptomyces brunneus CR22 AZP20754.1    
 EJC51_44645   Streptomyces brunneus CR22 AZP22548.1    
 EJC51_44370   Streptomyces brunneus CR22 AZP22499.1    
 IHE65_02120   Streptomyces caniscabiei ID-03-3A WEO22028.1    
 IHE65_11790   Streptomyces caniscabiei ID-03-3A WEO23801.1    
 IHE65_11845   Streptomyces caniscabiei ID-03-3A WEO23811.1    
 OG925_04975   Streptomyces canus NBC_01585 WSD83683.1    
 OG925_15715   Streptomyces canus NBC_01585 WSD85652.1    
 N0X72_22880   Streptomyces carpaticus SCPM-O-B-9993 UWM51622.1    
 NRO40_01540   Streptomyces changanensis HL-66 UUS29646.1    
 CP983_12275   Streptomyces chartreusis ATCC 14922 QEV67373.1    
 HUT05_13750   Streptomyces chartreusis NA02069 QKZ18330.1    
 IPT68_29535   Streptomyces chromofuscus DSM 40273 QOV43791.1    
 STRCI_005889   Streptomyces cinnabarinus DSM 40467 WAZ24469.1    
 STRCI_005892   Streptomyces cinnabarinus DSM 40467 WAZ24472.1    
 STRCI_006452   Streptomyces cinnabarinus DSM 40467 WAZ24992.1    
 SCO1187 (CelB;SCG11A.18)   Streptomyces coelicolor A3(2) CAB61599.1
AHA82090.1
NP_625477.1
   
 SCO5691 or SC5H4.15   Streptomyces coelicolor A3(2) CAB91127.1
AHA82092.1
NP_629819.1
   
 FQ762_05970   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI41414.1    
 FQ762_29400   Streptomyces coelicolor A3(2) CFB_NBC_0001 QFI45547.1    
 JCM4020_57830   Streptomyces coelicolor JCM 4020 BDD75163.1    
 JCM4020_13150   Streptomyces coelicolor JCM 4020 BDD70695.1    
 HCU77_05750   Streptomyces coelicolor M1154/pAMX4/pGP1416 QKN65066.1    
 HCU77_28840   Streptomyces coelicolor M1154/pAMX4/pGP1416 QKN69138.1    
 RE436_05800   Streptomyces coelicolor M22 WMT31941.1    
 RE436_28540   Streptomyces coelicolor M22 WMT36132.1    
 CP976_31310   Streptomyces coeruleorubidus ATCC 13740 QEV28160.1    
 PV963_33340   Streptomyces coeruleorubidus DM WDV54897.1    
 R5U08_06905   Streptomyces coeruleorubidus WT-48 WOT33896.1    
 RFN52_29295   Streptomyces collinus CGMCC 4.1623 WMX67237.1    
 QU709_10925   Streptomyces coralus SX92 WLW51854.1    
 QU709_10960   Streptomyces coralus SX92 WLW51861.1    
 EJ357_02120   Streptomyces cyaneochromogenes MK-45 AZQ32392.1    
 EJ357_45590   Streptomyces cyaneochromogenes MK-45 AZQ39807.1    
 EJ357_42250   Streptomyces cyaneochromogenes MK-45 AZQ39250.1    
 TU94_24000   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP04081.1    
 TU94_04665   Streptomyces cyaneogriseus subsp. noncyanogenus NMWT 1 AJP00870.1    
 S1361_02135 (CeX)   Streptomyces cyanogenus S136 QTD96124.1    
 N8I84_33915   Streptomyces cynarae HUAS 13-4 UXY23141.1    
 N8I84_28695   Streptomyces cynarae HUAS 13-4 UXY22231.1    
 D9753_09715   Streptomyces dangxiongensis Z022 AYN39137.1    
 D9753_09200   Streptomyces dangxiongensis Z022 AYN39063.1    
 BN159_2113 (Cela1)   Streptomyces davaonensis JCM 4913 CCK26492.1    
 L3078_42550   Streptomyces deccanensis KCTC 19241 ULR55429.1    
 L3078_32810   Streptomyces deccanensis KCTC 19241 ULR53679.1    
 L3078_32865   Streptomyces deccanensis KCTC 19241 ULR53688.1    
 NEH16_03890   Streptomyces drozdowiczii MDA8-470 UZK53385.1    
 M4V62_37445   Streptomyces durmitorensis MS405 UQT60296.1    
 PS783_26355   Streptomyces enissocaesilis NBF 715 WDI20907.1    
 PS783_05815   Streptomyces enissocaesilis NBF 715 WDI17122.1    
 GFH48_02010   Streptomyces fagopyri QMT-28 QFZ72192.1    
 IM697_34855   Streptomyces ferrugineus CCTCC AA2014009 QOV35212.1    
 CNQ36_33210   Streptomyces fungicidicus TXX3120 AYL40285.1    
 CNQ36_28460   Streptomyces fungicidicus TXX3120 AYL38990.1    
 CP966_26540   Streptomyces galilaeus ATCC 14969 QEU68418.1    
 IAG43_02950   Streptomyces genisteinicus CRPJ-33 QNP61983.1    
 SGLAU_26650   Streptomyces glaucescens GLA.O AIS01268.1    
 SGLAU_24490   Streptomyces glaucescens GLA.O AIS00840.1    
 SGFS_038770   Streptomyces graminofaciens A-8890 BBC32583.1    
 SGFS_100500   Streptomyces graminofaciens A-8890 BBC38756.1    
 AVL59_24080   Streptomyces griseochromogenes ATCC 14511 ANP52219.1    
 HEP81_00532   Streptomyces griseofuscus DSM 40191 QNT90868.1    
 UBV09_24755   Streptomyces griseoincarnatus HNS054 WPW21694.1    
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