Glycoside Hydrolase Family 12

Activities in Familyendoglucanase (EC 3.2.1.4); xyloglucan hydrolase (EC 3.2.1.151); β-1,3-1,4-glucanase (EC 3.2.1.73); xyloglucan endotransglycosylase (EC 2.4.1.207)
Mechanism Retaining
ClanGH-C
3D Structure Statusβ-jelly roll
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorGlu (experimental)
Noteformerly known as cellulase family H.
External resourcesCAZypedia; HOMSTRAD;
Commercial Enzyme Provider(s)MEGAZYME;
Statistics GenBank accession (953); Uniprot accession (212); PDB accession (48); 3D entries (17); cryst (1)
All (762) Archaea (81) Bacteria (532) Eukaryota (148) unclassified (1) Structure (17 - 1 cryst) Characterized (68)
| 1 | 2 | 3 | 4 | 5 | 6 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 DICTH_0465   Dictyoglomus thermophilum H-6-12 ACI19111.1
AAE50602.1
B5YCT9  
 Dtur_0628   Dictyoglomus turgidum DSM 6724 ACK41916.1 B8DZI3  
 SJ05684_a38100 (fragment)   Ensifer sojae CCBAU 05684 ASY67124.1    
 FLA_2599   Filimonas lacunae NBRC 104114 BAV06580.1    
 AciX8_3578   Granulicella mallensis MP5ACTX8 AEU37871.1    
 Kfla_1833   Kribbella flavida DSM 17836 ADB30927.1 D2PPG5  
 KALB_6077   Kutzneria albida DSM 43870 AHH99437.1    
 Cphy_1640   Lachnoclostridium phytofermentans ISDg ABX42012.1 A9KRD8  
 BBK82_34710   Lentzea guizhouensis DHS C013 ANZ40407.1    
 BBK82_39665   Lentzea guizhouensis DHS C013 ANZ43404.1    
 A6B35_33930   Mesorhizobium amorphae CCNWGS0123 ANT54932.1    
 MCHK_8157   Mesorhizobium huakuii 7653R AID34747.1    
 Micau_1146   Micromonospora aurantiaca ATCC 27029 ADL44708.1 D9TD70  
 GA0070611_5722   Micromonospora auratinigra DSM 44815 SBT52643.1    
 GA0070611_1216   Micromonospora auratinigra DSM 44815 SBT40329.1    
 GA0070612_0114   Micromonospora chokoriensis DSM 45160 SCE67032.1    
 GA0070607_1436   Micromonospora coriariae DSM 44875 SCE77676.1    
 GA0070614_4389   Micromonospora coxensis DSM 45161 SCG68428.1    
 GA0070609_4691   Micromonospora echinaurantiaca DSM 43904 SCG72344.1    
 GA0070610_4471   Micromonospora echinofusca DSM 43913 SCG18134.1    
 GA0070618_0797   Micromonospora echinospora DSM 43816 SCE77089.1    
 GA0070620_3176   Micromonospora krabiensis DSM 45344 SBV27650.1    
 GA0070621_5881   Micromonospora narathiwatensis DSM 45248 SBT55060.1    
 GA0074696_5473   Micromonospora purpureochromogenes DSM 43821 SCF40982.1    
 GA0070623_2551   Micromonospora rifamycinica DSM 44983 SCG57761.1    
 GA0074704_4041   Micromonospora siamensis DSM 45097 SCG64634.1    
 GA0074704_1807   Micromonospora siamensis DSM 45097 SCG45894.1    
 ML5_1409   Micromonospora sp. L5 ADU06947.1 D3CAR1  
 CO540_13740   Micromonospora sp. WMMA2032 ATO14757.1    
 GA0070619_0351   Micromonospora zamorensis DSM 45600 SCG36477.1    
 glycoside hydrolase family GH12 protein (Cel12) (fragment)   Mycobacterium africanum ADG63154.1 D6MNR4  
 RN09_1352 (fragment)   Mycobacterium africanum 25 AMC63100.1    
 MAF_11050 (Cela2B) (fragment)   Mycobacterium africanum GM041182 CCC26177.1    
 AZ248_06165 (fragment)   Mycobacterium africanum UT307 AMQ38043.1    
 Mb1595_p1235 (fragment)   Mycobacterium bovis 1595 AKR00758.1    
 RN07_1193 (fragment)   Mycobacterium bovis 30 AMC54424.1    
 Mb1120 (CelA2b) (fragment)   Mycobacterium bovis AF2122/97 SIT99720.1
CAD93981.1
CDO42366.1
NP_854776.1
   
 LH58_06005 (fragment)   Mycobacterium bovis ATCC BAA-935 AIR46387.1    
 RN06_1368 (fragment)   Mycobacterium bovis BCG 26 AMC49821.1    
 GS11_1187 (fragment)   Mycobacterium bovis BCG 3281 AKO24113.1    
 BCGR_1219 (Cela2B) (fragment)   Mycobacterium bovis BCG Russia 368 ALA77536.1    
 BCGT_0915 (fragment)   Mycobacterium bovis BCG str. ATCC 35743 63839 AHM06836.1    
 K60_011740 (fragment)   Mycobacterium bovis BCG str. Korea 1168P AGE67084.1    
 BCGMEX_1122 (fragment)   Mycobacterium bovis BCG str. Mexico AET18405.1    
 BCGM_1116 (Cela2B) (fragment)   Mycobacterium bovis BCG str. Moreau RDJ CCC63709.1    
 BCG_1150 (fragment)   Mycobacterium bovis BCG str. Pasteur 1173P2 CAL71137.1 A1KHN0  
 JTY_1123 (Cela2B) (fragment)   Mycobacterium bovis BCG str. Tokyo 172 BAH25413.1 C1AM84  
 AZH48_05805   Mycobacterium bovis BCG str. Tokyo 172 substrain TRCS AMO09690.1    
 AA885_05855 (fragment)   Mycobacterium bovis BCG-1 ALE42928.1    
 BOVR_05810 (fragment)   Mycobacterium bovis BCG-1 (Russia) ALV10280.1    
 SZ58_000615 (fragment)   Mycobacterium bovis SP38 ANG87005.1    
 glycoside hydrolase family GH12 protein (Cel12) (fragment)   Mycobacterium canettii ADG63155.1 D6MNR5  
 MCAN_10991 (Cela2B) (fragment)   Mycobacterium canettii CIPT 140010059 CCC43435.1    
 glycoside hydrolase family GH12 protein (Cel12) (fragment)   Mycobacterium caprae ADG63157.1 D6MNR7  
 B1T51_19920   Mycobacterium kansasii 10MK ARG76359.1    
 B1T52_20365   Mycobacterium kansasii 11MK ARG81895.1    
 B1T43_08285   Mycobacterium kansasii 1MK ARG55862.1    
 B1T45_08480   Mycobacterium kansasii 4MK ARG61325.1    
 B1T45_08305 (fragment)   Mycobacterium kansasii 4MK ARG61298.1    
 B1T47_08120   Mycobacterium kansasii 6MK ARG69011.1    
 B1T50_20805   Mycobacterium kansasii 9MK ARG93983.1    
 glycoside hydrolase family GH12 protein (Cel12) (fragment)   Mycobacterium microti ADG63156.1 D6MNR6  
 RN08_1224 (fragment)   Mycobacterium microti 12 AMC58651.1    
 glycoside hydrolase family GH12 protein (Cel12) (fragment)   Mycobacterium pinnipedii ADG63158.1 D6MNR8  
 CP498_06130 (fragment)   Mycobacterium sp. 3/86Rv ATI67031.1    
 IU21_14050 (fragment)   Mycobacterium tuberculosis 0A005DS AIH99696.1    
 IU23_13660 (fragment)   Mycobacterium tuberculosis 0A012DS AIH96764.1    
 IU20_13660 (fragment)   Mycobacterium tuberculosis 0A029DS AIH93005.1    
 IU19_13735 (fragment)   Mycobacterium tuberculosis 0A033DS AIH89276.1    
 IU15_14220 (fragment)   Mycobacterium tuberculosis 0A036DS AIH85949.1    
 IU22_13720 (fragment)   Mycobacterium tuberculosis 0A087DS AIH82905.1    
 IU14_13605 (fragment)   Mycobacterium tuberculosis 0A092DS AIH79158.1    
 IU24_13635 (fragment)   Mycobacterium tuberculosis 0A093DS AIH75416.1    
 IU18_13700 (fragment)   Mycobacterium tuberculosis 0A094DS AIH71702.1    
 IU17_13730 (fragment)   Mycobacterium tuberculosis 0A115DS AIH68119.1    
 IU16_13850 (fragment)   Mycobacterium tuberculosis 0A117DS AIH64806.1    
 IU13_13900 (fragment)   Mycobacterium tuberculosis 0B026XDR AIH61475.1    
 IU12_14545 (fragment)   Mycobacterium tuberculosis 0B049XDR AIH58654.1    
 IQ41_13350 (fragment)   Mycobacterium tuberculosis 0B070XDR AIH56009.1    
 IQ38_14280 (fragment)   Mycobacterium tuberculosis 0B076XDR AIH52705.1    
 IQ39_13435 (fragment)   Mycobacterium tuberculosis 0B123ND AIH49761.1    
 IQ40_13755 (fragment)   Mycobacterium tuberculosis 0B169XDR AIH46276.1    
 IQ48_13775 (fragment)   Mycobacterium tuberculosis 0B218DS AIH43180.1    
 IQ42_13915 (fragment)   Mycobacterium tuberculosis 0B222DS AIH39811.1    
 IQ47_13705 (fragment)   Mycobacterium tuberculosis 0B228DS AIH36473.1    
 IQ45_13730 (fragment)   Mycobacterium tuberculosis 0B229DS AIH32996.1    
 T209_13685 (fragment)   Mycobacterium tuberculosis 0B235DS AIH29531.1    
 IQ46_13575 (fragment)   Mycobacterium tuberculosis 0B259XDR AIH25860.1    
 IQ43_13560 (fragment)   Mycobacterium tuberculosis 0B329XDR AIH22066.1    
 BTB1458_1215 (Cela2B) (fragment)   Mycobacterium tuberculosis 1458 AOZ42219.1    
 MT18B_1443 (fragment)   Mycobacterium tuberculosis 18b AJK61120.1    
 RN14_1174 (fragment)   Mycobacterium tuberculosis 22103 AMC85222.1    
 RN12_1176 (fragment)   Mycobacterium tuberculosis 22115 AMC76785.1    
 RN10_1251 (fragment)   Mycobacterium tuberculosis 2242 AMC67797.1    
 RN11_1283 (fragment)   Mycobacterium tuberculosis 2279 AMC72293.1    
 RN15_1175 (fragment)   Mycobacterium tuberculosis 26105 AMC89407.1    
 RN13_1176 (fragment)   Mycobacterium tuberculosis 37004 AMC80995.1    
 MT49_1188 (Cela2B) (fragment)   Mycobacterium tuberculosis 49-02 CDM09351.1    
 IQ44_13650 (fragment)   Mycobacterium tuberculosis 6A024XDR AIH18280.1    
 MT7199_1117 (fragment)   Mycobacterium tuberculosis 7199-99 CCG10966.1    
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