Activities in Family	β-1,3-glucanase (EC 3.2.1.39); β-1,3-glucosidase (EC 3.2.1.-)
Mechanism	Retaining
Clan	GH-A
3D Structure Status	( β / α ) 8 barrel
Catalytic Nucleophile/Base	Glu
Catalytic Proton Donor	Glu
Note	Created following a paper by Sakamoto and colleagues (PMID:21965406); distantly related to clan GH-A; Mechanism, Fold and catalytic aminoacids have been determinated by Santos and al. (10.1038/s41589-020-0554-5)
Statistics	GenBank accession (672); Uniprot accession (7); PDB accession (24); 3D entries (8); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
endo-β-1,3-glucanase (AmGH128_I;RAM_19160)	3.2.1.39	Amycolatopsis mediterranei S699	AEK42318.1 AFO77254.1	G0FQ07	6UAQ[A] 1.15 6UAR[A] β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.40 6UAS[A] β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-α-D-Glcp 1.91 6UAT[A] β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.90 6UAU[A] β-D-Glcp-(1-3)-β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.90 6UFL[A] β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.61 6UFZ[A] 1.90
endo-β-1,3-glucanase (PvGH128_II;CFBP1590__2373)	3.2.1.39	Pseudomonas viridiflava CFBP 1590	SMS09959.1	A0A1Y6JJH6	6UAV[A] 1.50 6UAW[A] β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.50
endo-β-1,3-glucanase (ScGH128_II;sce3275)	3.2.1.39	Sorangium cellulosum So ce56	CAN93434.1	A9GMG4	6UAX[A,B] 1.30
Eukaryota
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
AnGH128_VI (M436DRAFT_66913)	3.2.1.-	Aureobasidium namibiae CBS 147.97	KEQ69643.1	A0A074W9U7	6UB8[A,B,C,D,E,F,G,H,I,J] 1.90 6UBA[A,B,C,D,E,F,G,H,I,J] β-D-Glcp-(1-3)-β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 2.40 6UBB[A,B,C,D,E,F,G,H,I,J] β-D-Glcp-(1-3)-β-D-Glcp 2.35
BgGH128_III (BDBG_03339)	3.2.1.-	Blastomyces gilchristii SLH14081	OAT07255.1	A0A179UGT5	6UAY[A,B] 1.80 6UAZ[A,B] β-D-Glcp 1.85 6UB0[A] β-D-Glcp-(1-3)-α-D-Glcp 1.75 6UB1[A,B,C,D] β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp 1.60
CnGH128_V (CNAG_02661)	3.2.1.-	Cryptococcus neoformans var. grubii H99	AFR94030.1	J9VQQ4	6UB7[A] 1.80
endo-β-1,3-glucanase (LeGH128_IV;GLU1)	3.2.1.39	Lentinula edodes H600	BAL27560.1	G9M5R4	6UB2[A,B,C,D] 1.80 6UB3[A,B] β-D-Glcp-(1-3)-β-D-Glcp 1.85 6UB4[A,B] β-D-Glcp-(1-3)-β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.60 6UB5[A] β-D-Glcp-(1-3)-β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.30 6UB6[A] β-D-Glcp-(1-3)-β-D-Glcp β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp-(1-3)-β-D-Glcp 1.25
TgGH128_VII (TGAMA5MH_01007)		Trichoderma gamsii A5MH	PNP47955.1		6UBD[A] 1.25
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