Glycoside Hydrolase Family 125

Activities in Familyexo-α-1,6-mannosidase (EC 3.2.1.-)
Mechanism inverting
ClanGH-G
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu
Catalytic Proton DonorAsp
NoteCreated after Gregg, Zandberg, Hehemann, Whitworth, Deng, Vocadlo & Boraston (2011) J Biol Chem 286:15586-96 [PMID:21388958]
External resourcesCAZypedia;
Statistics GenBank accession (1171); Uniprot accession (23); PDB accession (11); 3D entries (6); cryst (0)
| 1 | ... | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 spr1952   Streptococcus pneumoniae R6 NP_359543.1 Q8DN33  
 CGSSp11BS70_05635   Streptococcus pneumoniae SP11-BS70 ZP_01825569.1 A5M1X0  
 CGSSp14BS69_00650   Streptococcus pneumoniae SP14-BS69 ZP_01827900.1 A5M8K1  
 CGSSp19BS75_03083   Streptococcus pneumoniae SP19-BS75 ZP_01833155.1 A5MNK6  
 CGSSp3BS71_10313   Streptococcus pneumoniae SP3-BS71 ZP_01817728.1 A5LBN2  
 BMJ42_02221   Streptococcus pneumoniae SP49 APJ31443.1    
 BOC71_02036   Streptococcus pneumoniae SP61 APJ33463.1    
 BOC72_02038   Streptococcus pneumoniae SP64 APJ35488.1    
 CGSSp9BS68_10975   Streptococcus pneumoniae SP9-BS68 ZP_01821778.1 A5LR29  
 SPN034156_09720   Streptococcus pneumoniae SPN034156 SNP034156 CCP36641.1    
 SPN034183_18950   Streptococcus pneumoniae SPN034183 SNP034183 CCP33605.1    
 SPN994038_18840   Streptococcus pneumoniae SPN994038 SNP994038 CCP31620.1    
 SPN994039_18850   Streptococcus pneumoniae SPN994039 SNP994039 CCP35579.1    
 SPNA45_00065   Streptococcus pneumoniae SPNA45 CCM07355.1    
 MYY_2064   Streptococcus pneumoniae ST556 AFC95716.1    
 SPT_2157   Streptococcus pneumoniae Taiwan19F-14 ACO23347.1    
 HMPREF0837_10146   Streptococcus pneumoniae TCH8431/19A ADI68374.1    
 exo-α-1,6-mannosidase (SpGH125;SP_2144) 3.2.1.- Streptococcus pneumoniae TIGR4 AAK76201.1   3QPF[A,B]
3QRY[A,B]
3QSP[A,B]
 CXP32_11080   Streptococcus pneumoniae Xen35 AUF85820.1    
 SPPN_11010   Streptococcus pseudopneumoniae IS7493 AEL11606.1    
 STAB904_07040   Streptococcus pyogenes 1E1 AIW12142.1    
 SP5448_03005   Streptococcus pyogenes 5448 AKK70037.1    
 STAB1101_05810   Streptococcus pyogenes 7F7 AIT77820.1    
 A20_1350   Streptococcus pyogenes A20 AFV38430.1    
 SPYALAB49_001294   Streptococcus pyogenes Alab49 AEQ24887.1    
 SPAP1_02915   Streptococcus pyogenes AP1 AKG27573.1    
 AUQ45_1303 (Hypo17)   Streptococcus pyogenes AP53 AMY97857.1    
 DP15_384   Streptococcus pyogenes ATCC 19615 AIL11893.1    
 SpyM6D471_06020   Streptococcus pyogenes D471 AKI78168.1    
 AL510_06470   Streptococcus pyogenes FDAARGOS_149 AMH03487.1    
 B2G65_03305   Streptococcus pyogenes GUR ASO73772.1    
 CFA72_03305   Streptococcus pyogenes GURSA1 ASO68056.1    
 SPYH293_01195   Streptococcus pyogenes H293 CDJ55443.1    
 CRD75_06605   Streptococcus pyogenes HarveyGAS ATL57229.1    
 HKU360_01355   Streptococcus pyogenes HKU360 AIW25158.1    
 HKU488_01254   Streptococcus pyogenes HKU488 AKP82183.1    
 L897_06545   Streptococcus pyogenes HSC5 AGQ27955.1    
 JMUB1235_1226   Streptococcus pyogenes JMUB1235 BAV55480.1    
 SPYJRS4_1262   Streptococcus pyogenes JRS4 BAR44762.1
AKI76497.1
   
 CCX85_06540   Streptococcus pyogenes JS12 AUG50776.1    
 SPYKS030_05730   Streptococcus pyogenes KS030 BBB87975.1    
 M1GAS476_1383   Streptococcus pyogenes M1 476 BAM30712.2    
 SPy_1603   Streptococcus pyogenes M1 GAS AAK34380.1    
 FE90_1015   Streptococcus pyogenes M23ND AIQ01778.1    
 ABO05_02680   Streptococcus pyogenes M28PF1 AKJ92193.1    
 M3B_0650   Streptococcus pyogenes M3-b BAU60020.1    
 AWM59_02720   Streptococcus pyogenes MEW123 AMA70171.1    
 AWM58_06375   Streptococcus pyogenes MEW427 AMA69269.1    
 MGAS10270_Spy1432   Streptococcus pyogenes MGAS10270 ABF34497.1    
 M6_Spy1334   Streptococcus pyogenes MGAS10394 AAT87469.1    
 MGAS10750_Spy1425 (fragment)   Streptococcus pyogenes MGAS10750 ABF38375.1    
 MGAS11027_1271   Streptococcus pyogenes MGAS11027 ANC24261.1    
 MGAS15252_1201   Streptococcus pyogenes MGAS15252 AFC66537.1    
 MGAS1882_1262   Streptococcus pyogenes MGAS1882 AFC68467.1    
 MGAS2096_Spy1337   Streptococcus pyogenes MGAS2096 ABF36389.1    
 MGAS23530_1180   Streptococcus pyogenes MGAS23530 ANC25856.1    
 MGAS27061_1216   Streptococcus pyogenes MGAS27061 ANC27485.1    
 SpyM3_1296 (fragment)   Streptococcus pyogenes MGAS315 AAM79903.1    
 M5005_Spy1316   Streptococcus pyogenes MGAS5005 AAZ51934.1    
 M28_Spy1357   Streptococcus pyogenes MGAS6180 AAX72467.1    
 spyM18_1610   Streptococcus pyogenes MGAS8232 AAL98165.1    
 MGAS9429_Spy1310   Streptococcus pyogenes MGAS9429 ABF32497.1    
 MTB313_1333   Streptococcus pyogenes MTB313 BAQ51740.1    
 MTB314_1252   Streptococcus pyogenes MTB314 BAQ53415.1    
 ERS445054_01438   Streptococcus pyogenes NCTC8198 CKH04937.1    
 SD89_02730   Streptococcus pyogenes NGAS322 AKZ50038.1    
 DK93_02695   Streptococcus pyogenes NGAS327 AKI38370.1    
 DK92_02810   Streptococcus pyogenes NGAS596 AKI36761.1    
 SD90_06070   Streptococcus pyogenes NGAS638 AKZ52497.1    
 DI45_07485   Streptococcus pyogenes NGAS743 AKI35835.1    
 A4265_05850   Streptococcus pyogenes NS53 ANC74793.1    
 A4265_05850   Streptococcus pyogenes NS53 ANC74793.2    
 Spy49_1238   Streptococcus pyogenes NZ131 ACI61524.1    
 ORF   Streptococcus pyogenes SSI-1 BAC63660.1    
 VT08_06490   Streptococcus pyogenes STAB09014 ANP29861.1    
 B4W66_06555   Streptococcus pyogenes STAB090229 ASQ21557.1    
 VU19_06975   Streptococcus pyogenes STAB10015 AKL63574.1    
 STAB1102_06485   Streptococcus pyogenes STAB1102 AIG49219.1    
 B5D85_07225   Streptococcus pyogenes STAB120304 ASQ23432.1    
 AXK13_06425   Streptococcus pyogenes STAB13021 AND05197.1    
 AYM92_07035   Streptococcus pyogenes STAB14018 ARV01659.1    
 STAB901_06565   Streptococcus pyogenes STAB901 AIG50642.1    
 STAB902_03215   Streptococcus pyogenes STAB902 AIG46860.1    
 SpyM50539   Streptococcus pyogenes str. Manfredo CAM29877.1    
 HMPREF0847_01776   Streptococcus sp. 2_1_36FAA ZP_06061174.1 D0RWV5  
 ATM98_07860   Streptococcus sp. A12 AMP67632.1    
 N596_08230   Streptococcus sp. I-G2 AGY40724.1    
 N597_00140   Streptococcus sp. I-P16 AGY37406.1    
 SNAG_1799   Streptococcus sp. NPS 308 BAV80668.1    
 AXF18_03855   Streptococcus sp. oral taxon 064 W10853 ANR75088.1    
 AXE83_00005   Streptococcus sp. oral taxon 431 F0610 (5-114) AMD96071.1    
 V470_09465   Streptococcus sp. VT 162 AHZ48633.1    
 SSU05_1920   Streptococcus suis 05ZYH33 ABP90886.1    
 ID09_09840   Streptococcus suis 6407 AIG44309.1    
 SSU98_1924   Streptococcus suis 98HAH33 ABP93082.1    
 SSUA7_1740   Streptococcus suis A7 AER45057.1    
 SSUBM407_1784   Streptococcus suis BM407 CAZ56640.1    
 SSUD12_1891   Streptococcus suis D12 AER20159.1    
 A6M16_09095   Streptococcus suis DN13 AND00633.1    
 BFP66_08990   Streptococcus suis GZ0565 AOM75356.1    
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