Glycoside Hydrolase Family 116

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-xylosidase (EC 3.2.1.37); acid β-glucosidase/β-glucosylceramidase (EC 3.2.1.45); β-N-acetylglucosaminidase (EC 3.2.1.52)
Mechanism Retaining
ClanGH-O
3D Structure Status( α / α ) 6 barrel
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorAsp (experimental)
NoteSubfamilies described in Ferrara et al. (2013) BBA 1840:367-377 (PMID:24060745)
External resourcesCAZypedia;
Statistics GenBank accession (1095); Uniprot accession (10); PDB accession (22); 3D entries (1); cryst (0)
Bacteria
Protein Name EC#OrganismGenBankUniprot
PDB/3D Carbohydrate Ligands Resolution (Å)
 β-glucosidase (TxGH116;Thexy_2211) 3.2.1.21 Thermoanaerobacterium xylanolyticum LX-11 AEF18218.1 F6BL85
5BVU[A] 1.61
5BX2[A] α-D-Glcp2F-(1-4)-GLU
1.61
5BX3[A] <carb_like_NOJ>
1.96
5BX4[A] <carb_like_GIM>
1.65
5BX5[A] β-D-Glcp
1.85
5FJS[A,B] 2.60
5NCX[A] 1.70
5NPF[A] 1.38
5O0S[A] 1.16
5OST[A] 2.10
7DKS[A] 1.65
7DKT[A] α-D-Glcp1F
1.65
7DKU[A] β-D-Glcp-(1-4)-β-D-Glcp
1.60
7DKV[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp
1.70
7DKW[A,B] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp
β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp
1.78
7DKX[A] β-D-Glcp-(1-4)-β-D-Glcp
1.70
7DKY[A] β-D-Glcp-(1-4)-β-D-Glcp-(1-4)-β-D-Glcp
1.95
7W2S[A] β-D-Glcp
1.85
7W2T[A,B] β-D-Glcp
2.15
7W2V[A] β-D-Glcp
1.80
7W2W[A] α-D-Glcp
1.79
7W2X[A] 1.80
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