Glycoside Hydrolase Family 116

Activities in Familyβ-glucosidase (EC 3.2.1.21); β-xylosidase (EC 3.2.1.37); acid β-glucosidase/β-glucosylceramidase (EC 3.2.1.45); β-N-acetylglucosaminidase (EC 3.2.1.52)
Mechanism Retaining
ClanGH-O
3D Structure Status( α / α ) 6
Catalytic Nucleophile/BaseGlu (experimental)
Catalytic Proton DonorAsp (experimental)
NoteSubfamilies described in Ferrara et al. (2013) BBA 1840:367-377 (PMID:24060745)
External resourcesCAZypedia;
Statistics GenBank accession (488); Uniprot accession (131); PDB accession (9); 3D entries (1); cryst (0)
Archaea
Protein Name EC#OrganismGenBank UniprotPDB/3D
 Ahos_0327   Acidianus hospitalis W1 AEE93218.1    
 Ahos_0332   Acidianus hospitalis W1 AEE93223.1    
 Ahos_0346   Acidianus hospitalis W1 AEE93237.1    
 B6F84_05115   Acidianus manzaensis YN-25 ARM75470.1    
 B6F84_04930   Acidianus manzaensis YN-25 ARM75436.1    
 B6F84_00180   Acidianus manzaensis YN-25 ARM74600.1    
 B6F84_05070   Acidianus manzaensis YN-25 ARM75461.1    
 ASAC_0609   Acidilobus saccharovorans 345-15 ADL19016.1 D9Q128  
 SE86_03575   Acidilobus sp. 7A AMD30568.1    
 Cmaq_1276   Caldivirga maquilingensis IC-167 ABW02103.1 A8ME97  
 Cmaq_1638   Caldivirga maquilingensis IC-167 ABW02461.1 A8M9Z0  
 BglU (fragment)   Sulfolobus islandicus ADO41147.1 E3VNG8  
 BglU (fragment)   Sulfolobus islandicus ADO41148.1 E3VNG9  
 BglU (fragment)   Sulfolobus islandicus ADO41149.1 E3VNH0  
 BglU (fragment)   Sulfolobus islandicus ADO41150.1 E3VNH1  
 SiH_2258   Sulfolobus islandicus HVE10/4 ADX83599.1    
 SiH_2592   Sulfolobus islandicus HVE10/4 ADX83929.1    
 SiH_0384   Sulfolobus islandicus HVE10/4 ADX81753.1    
 LD85_0902 (probable fragment)   Sulfolobus islandicus L.D.8.5 ADB86607.1 D2PIB3  
 LD85_0961   Sulfolobus islandicus L.D.8.5 ADB86661.1 D2PIG7  
 LD85_2606   Sulfolobus islandicus L.D.8.5 ADB88227.1 D2PFW1  
 LD85_2956   Sulfolobus islandicus L.D.8.5 ADB88551.1 D2PHW6  
 LS215_0672   Sulfolobus islandicus L.S.2.15 ACP34750.1 C3MMC7  
 LS215_2489   Sulfolobus islandicus L.S.2.15 ACP36451.1 C3ML49  
 LS215_2801   Sulfolobus islandicus L.S.2.15 ACP36736.1 C3MML9  
 SiL_2481   Sulfolobus islandicus LAL14/1 AGJ63914.1    
 SiL_0365   Sulfolobus islandicus LAL14/1 AGJ61840.1    
 SiL_2167   Sulfolobus islandicus LAL14/1 AGJ63608.1    
 M1425_0924   Sulfolobus islandicus M.14.25 ACP37718.1 C3MX38  
 M1425_2317   Sulfolobus islandicus M.14.25 ACP39048.1 C3MSA5  
 M1425_2640   Sulfolobus islandicus M.14.25 ACP39349.1 C3MT56  
 M1627_0991   Sulfolobus islandicus M.16.27 ACP54914.1 C3N4I9  
 M1627_2396   Sulfolobus islandicus M.16.27 ACP56253.1 C3N1M6  
 M1627_2694   Sulfolobus islandicus M.16.27 ACP56531.1 C3N334  
 M164_0933   Sulfolobus islandicus M.16.4 ACR41546.1 C4KG32  
 M164_2319   Sulfolobus islandicus M.16.4 ACR42918.1 C4KKQ6  
 M164_2625   Sulfolobus islandicus M.16.4 ACR43217.1 C4KEV4  
 SiRe_2202   Sulfolobus islandicus REY15A ADX86256.1    
 SiRe_0792   Sulfolobus islandicus REY15A ADX84873.1    
 SiRe_2531   Sulfolobus islandicus REY15A ADX86576.1    
 YG5714_0710   Sulfolobus islandicus Y.G.57.14 ACP45000.1 C3NBL5  
 YG5714_2457   Sulfolobus islandicus Y.G.57.14 ACP46699.1 C3NAA6  
 YG5714_2812   Sulfolobus islandicus Y.G.57.14 ACP47031.1 C3NCC5  
 YN1551_0454   Sulfolobus islandicus Y.N.15.51 ACP47613.1 C3NL99  
 YN1551_2495   Sulfolobus islandicus Y.N.15.51 ACP49446.1 C3NKX3  
 YN1551_3001   Sulfolobus islandicus Y.N.15.51 ACP49888.1 C3NFF4  
 Ssol_0489   Sulfolobus solfataricus 98/2 ACX90768.1 D0KPC4  
 Ssol_2754   Sulfolobus solfataricus 98/2 ACX92838.1 D0KPT4  
 Ssol98_010100007941   Sulfolobus solfataricus 98/2 AET42959.1    
 SULC_0818   Sulfolobus solfataricus 98/2 SULC AKA75881.1    
 SULC_0479   Sulfolobus solfataricus 98/2 SULC AKA75583.1    
 SULC_2772   Sulfolobus solfataricus 98/2 SULC AKA77531.1    
 SSOP1_2077   Sulfolobus solfataricus P1 SAI85631.1    
 SSOP1_2797   Sulfolobus solfataricus P1 SAI86351.1    
 SSOP1_1470 (fragment)   Sulfolobus solfataricus P1 SAI85024.1    
 SSOP1_1468 (fragment)   Sulfolobus solfataricus P1 SAI85022.1    
 SSOP1_3134   Sulfolobus solfataricus P1 SAI86688.1    
 SSO2674   Sulfolobus solfataricus P2 AAK42792.1
NP_344002.1
Q97VF2  
 aryl β-glucosidase/β-xylosidase (SSO1353) 3.2.1.21
3.2.1.37
Sulfolobus solfataricus P2 AAK41589.1
NP_342799.1
Q97YG8  
 SSO1948   Sulfolobus solfataricus P2 AAK42141.1
NP_343351.1
Q97X09  
 bifunctional β-glucosidase / β-N-acetylglucosaminidase (sso3039;SSO3039) 3.2.1.21
3.2.1.52
Sulfolobus solfataricus P2 AAK43141.1
NP_344351.1
Q97UH8  
 SULA_0818   Sulfolobus solfataricus SULA AKA78573.1    
 SULA_2774   Sulfolobus solfataricus SULA AKA80221.1    
 SULA_0479   Sulfolobus solfataricus SULA AKA78276.1    
 SULB_2775   Sulfolobus solfataricus SULB AKA74835.1    
 SULB_0820   Sulfolobus solfataricus SULB AKA73183.1    
 SULB_0481   Sulfolobus solfataricus SULB AKA72884.1    
 BFU36_08980   Sulfolobus sp. A20 AOL16816.1    
 BFU36_08975   Sulfolobus sp. A20 AOL16815.1    
 BFU36_07500   Sulfolobus sp. A20 AOL16565.1    
 ST2526   Sulfolobus tokodaii str. 7 BAB67640.1
NP_378531.1
Q96XI7  
 ST2609   Sulfolobus tokodaii str. 7 BAB67724.1
NP_378615.1
Q96XA4  
 ST0868   Sulfolobus tokodaii str. 7 BAB65880.1
NP_376771.1
Q973N2  
 ST2529   Sulfolobus tokodaii str. 7 BAB67642.1
NP_378533.1
Q96XI5  
 TUZN_0057   Thermoproteus uzoniensis 768-20 AEA11562.1    
 TUZN_0133   Thermoproteus uzoniensis 768-20 AEA11634.1    
 TUZN_1447   Thermoproteus uzoniensis 768-20 AEA12920.1    
Bacteria
Protein Name EC#OrganismGenBank UniprotPDB/3D
 PACID_30230   Acidipropionibacterium acidipropionici ATCC 4875 AFV90788.1    
 A8L58_09520   Acidipropionibacterium acidipropionici F3E8 AOZ46896.1    
 BWX38_07895   Acidipropionibacterium acidipropionici WSH1105 APZ09187.1    
 LuPra_00826   Acidobacteria bacterium DSM 100886 AMY07652.1    
 SAMN04489714_0911   Actinomyces radingae DSM 9169 SDT92117.1    
 SAMN04489717_3198   Actinopolymorpha singaporensis DSM 22024 SDS59678.1    
 SAMN04489717_3461   Actinopolymorpha singaporensis DSM 22024 SDS67253.1    
 APS56_09745   Algibacter alginicilyticus HZ22 ALJ05385.1    
 APS56_09795   Algibacter alginicilyticus HZ22 ALJ05392.1    
 APS56_05990   Algibacter alginicilyticus HZ22 ALJ04711.1    
 APS56_09805   Algibacter alginicilyticus HZ22 ALJ05394.1    
 Anacy_0939   Anabaena cylindrica PCC 7122 AFZ56515.1    
 ANA_C11968   Anabaena sp. 90 AFW94720.1    
 AA650_20430   Anabaena sp. wa102 ALB42504.1    
 NIES21_21590   Anabaenopsis circularis NIES-21 BAY16333.1    
 SAMN00777080_3520   Aquiflexum balticum DSM 16537 SMD44884.1    
 NIES39_J00300   Arthrospira platensis NIES-39 BAI91082.1 D4ZTG7  
 ARTHRO_12102   Arthrospira sp. PCC 8005 CDM94428.1    
 NIES50_23140   Aulosira laxa NIES-50 BAZ73748.1    
 CGC64_09735   Bacteroides caccae ATCC 43185 ASM66199.1    
 BcellWH2_01901   Bacteroides cellulosilyticus WH2 ALJ59152.1    
 BT_2908; BT2908   Bacteroides thetaiotaomicron VPI-5482 AAO78014.1    
 Bgl1 / BuBGL1   Bacteroides uniformis ZL1 AGU13697.1    
 Bcav_1712   Beutenbergia cavernae DSM 12333 ACQ79968.1 C5C455  
 CLDAP_33410   Caldilinea aerophila DSM 14535 = NBRC 104270 BAM01381.1    
 NIES22_42230   Calothrix brevissima NIES-22 BAY64129.1    
 NIES267_64070   Calothrix parasitica NIES-267 BAY86896.1    
 IJ00_13570   Calothrix sp. 336/3 AKG22153.1    
 NIES2098_43790   Calothrix sp. NIES-2098 BAY11199.1    
 NIES2100_61040   Calothrix sp. NIES-2100 BAY26290.1    
 NIES3974_29430   Calothrix sp. NIES-3974 BAZ06285.1    
 NIES4071_47990   Calothrix sp. NIES-4071 BAZ12965.1    
 NIES4101_32630   Calothrix sp. NIES-4101 BAZ37342.1    
 NIES4105_47930   Calothrix sp. NIES-4105 BAZ59111.1    
 Cal6303_3031   Calothrix sp. PCC 6303 AFZ01978.1    
 Cal7507_1645   Calothrix sp. PCC 7507 AFY32103.1    
 UCYN_12530   Candidatus Atelocyanobacterium thalassa isolate ALOHA ADB95919.1 D3ER19  
 Acid345_1688   Candidatus Koribacter versatilis Ellin345 ABF40689.1 Q1IR11  
 Acid_5570 (possible fragment)   Candidatus Solibacter usitatus Ellin6076 ABJ86517.1 Q01UZ8  
 Cha6605_5854   Chamaesiphon minutus PCC 6605 AFY96705.1    
 NIES4102_14870   Chondrocystis sp. NIES-4102 BAZ44477.1    
 Chro_5008   Chroococcidiopsis thermalis PCC 7203 AFY90385.1    
 CCALI_00294   Chthonomonas calidirosea T49 CCW34131.1    
 CCALI_00937   Chthonomonas calidirosea T49 CCW34759.1    
 Cwoe_3979   Conexibacter woesei DSM 14684 ADB52396.1 D3F3N1  
 Cri9333_4001   Crinalium epipsammum PCC 9333 AFZ14808.1    
 Cyan10605_1813   Cyanobacterium aponinum PCC 10605 AFZ53915.1    
 ETSB_0214   cyanobacterium endosymbiont of Epithemia turgida isolate ETSB Lake Yunoko BAP17101.1    
 RGRSB_0164   cyanobacterium endosymbiont of Rhopalodia gibberula BBA78783.1    
 Cyast_1832   Cyanobacterium stanieri PCC 7202 AFZ47788.1    
 Cyagr_1248   Cyanobium gracile PCC 6307 AFY28426.1    
 CBM981_2723   Cyanobium sp. NIES-981 SBO44422.1    
 cce_1609   Cyanothece sp. ATCC 51142 ACB50959.1 B1WXX2  
 PCC7424_0277   Cyanothece sp. PCC 7424 ACK68745.1 B7KAS3  
 Cyan7425_4519   Cyanothece sp. PCC 7425 ACL46829.1 B8HKI5  
 Cyan7822_1532   Cyanothece sp. PCC 7822 ADN13525.1 E0U5D5  
 PCC8801_2201   Cyanothece sp. PCC 8801 ACK66229.1 B7K082  
 Cyan8802_2263   Cyanothece sp. PCC 8802 ACV01142.1 C7QL95  
 NIES4074_17350   Cylindrospermum sp. NIES-4074 BAZ29293.1    
 Cylst_5355   Cylindrospermum stagnale PCC 7417 AFZ27380.1    
 NIES806_29300   Dolichospermum compactum NIES-806 BAZ86714.1    
 Fisuc_2704 / FSU_3272   Fibrobacter succinogenes subsp. succinogenes S85 ACX76287.1
ADL24607.1
C9RN35  
 OP10G_0381   Fimbriimonas ginsengisoli Gsoil 348 AIE83749.1    
 OP10G_2213   Fimbriimonas ginsengisoli Gsoil 348 AIE85581.1    
 OP10G_2213   Fimbriimonas ginsengisoli Gsoil 348 AIE85581.1    
 OP10G_1031   Fimbriimonas ginsengisoli Gsoil 348 AIE84399.1    
 ORF   Fischerella sp. MV11 ACN96073.1 E1U3R6  
 FIS3754_35550   Fischerella sp. NIES-3754 BAU07622.1    
 NIES4106_31610   Fischerella sp. NIES-4106 BAZ68399.1    
 D770_23945   Flammeovirgaceae bacterium 311 AHM63034.1    
 Franean1_4431   Frankia sp. EAN1pec ABW13810.1    
 NIES3275_45030   Fremyella diplosiphon NIES-3275 BAY92467.1    
 GEI7407_0159   Geitlerinema sp. PCC 7407 AFY64664.1    
 GM3708_1952   Geminocystis sp. NIES-3708 BAQ61546.1    
 GM3709_374   Geminocystis sp. NIES-3709 BAQ63609.1    
 GKIL_1460   Gloeobacter kilaueensis JS1 AGY57706.1    
 gll2460   Gloeobacter violaceus PCC 7421 BAC90401.1
NP_925406.1
Q7NHS5  
 Glo7428_0799   Gloeocapsa sp. PCC 7428 AFZ29383.1    
 AciX8_2245   Granulicella mallensis MP5ACTX8 AEU36563.1    
 Halhy_3646   Haliscomenobacter hydrossis DSM 1100 AEE51498.1    
 XM38_017100 (fragment)   Halomicronema hongdechloris C2206 ASC70763.1    
 Haur_0301   Herpetosiphon aurantiacus DSM 785 ABX02953.1 A9B7I0  
 SAMN04488563_5679 (fragment)   Jiangella alkaliphila DSM 45079 SDU77985.1    
 SAMN04488563_6101   Jiangella alkaliphila DSM 45079 SDU79988.1    
 SAMN04488563_6101   Jiangella alkaliphila DSM 45079 SDU79988.1    
 SAMN04488563_1734   Jiangella alkaliphila DSM 45079 SDU43712.1    
 SAMN04515669_5357   Jiangella sp. DSM 45060 SDT64102.1    
 SAMN04515669_1409   Jiangella sp. DSM 45060 SDS57727.1    
 SAMN04515683_2183   Leifsonia sp. 157MF SDK05958.1    
 SAMN04515690_3222   Leifsonia sp. 197AMF SDH59568.1    
 SAMN04515684_0566   Leifsonia sp. 466MF SDI79564.1    
 SAMN04515685_2168   Leifsonia sp. 467MF SEN24114.1    
 SAMN04515686_2768   Leifsonia sp. 509MF SDN83076.1    
 SAMN04515691_0798   Leifsonia sp. 98AMF SFL85784.1    
 LBDG_34680   Leptolyngbya boryana dg5 BAS63859.1    
 LBWT_34680   Leptolyngbya boryana IAM M-101 BAS57511.1    
 NIES2135_31240   Leptolyngbya boryana NIES-2135 BAY56293.1    
 LEP3755_60800   Leptolyngbya sp. NIES-3755 BAU15521.1    
 O77CONTIG1_01465   Leptolyngbya sp. O-77 BAU41653.1    
 Lepto7376_3439   Leptolyngbya sp. PCC 7376 AFY39644.1    
 VV02_05335 (fragment)   Luteipulveratus mongoliensis MN07-A0370 AKU18658.1    
 Mahau_0633   Mahella australiensis 50-1 BON AEE95836.1    
 Mic7113_0652   Microcoleus sp. PCC 7113 AFZ16565.1    
 amyaer_0299   Microcystis aeruginosa NIES-2481 AOC51050.1    
 MYAER_0300   Microcystis aeruginosa NIES-2549 AKE62662.1    
 MAE_08410   Microcystis aeruginosa NIES-843 BAG00663.1 B0JQK4  
 IPF_2113   Microcystis aeruginosa PCC 7806 CAO87856.1 A8YKF8  
 BH695_0738   Microcystis aeruginosa PCC 7806SL ARI80019.1    
 VL20_1029   Microcystis panniformis FACHB-1757 AKV66216.1    
 SAMN04489812_3983   Microlunatus soli DSM 21800 SDT05860.1    
 SAMN04489812_1189   Microlunatus soli DSM 21800 SDS20123.1    
 SAMN04489812_1189   Microlunatus soli DSM 21800 SDS20123.1    
 SAMN04489812_0996   Microlunatus soli DSM 21800 SDS13736.1    
 BJP36_31125   Moorea producens JHB AOY83708.1    
 BJP34_06730   Moorea producens PAL-8-15-08-1 AOW99186.1    
 A8C56_13025   Niabella ginsenosidivorans BS26 ANH83907.1    
 NIASO_00560   Niabella soli DSM 19437 AHF14094.1    
 NIASO_02420   Niabella soli DSM 19437 AHF17144.1    
 NSP_7870   Nodularia spumigena CCY9414 AHJ27135.1    
 Aazo_0722   Nostoc azollae 0708 ADI63175.1 D7E1E8  
 NIES2107_69730   Nostoc carneum NIES-2107 BAY35062.1    
 NIES25_33620   Nostoc linckia NIES-25 BAY76904.1    
 Npun_R1544   Nostoc punctiforme PCC 73102 ACC80233.1 B2J0L6  
 NIES2111_18210   Nostoc sp. NIES-2111 BAY37483.1    
 NOS3756_37230   Nostoc sp. NIES-3756 BAT54750.1    
 NIES4103_52170   Nostoc sp. NIES-4103 BAZ52553.1    
 Nos7107_4501   Nostoc sp. PCC 7107 AFY45032.1    
 alr2816   Nostoc sp. PCC 7120 BAB74515.1
AAC38131.1
NP_486856.1
Q8YTA7  
 Nos7524_0082   Nostoc sp. PCC 7524 AFY46008.1    
 BZZ01_24880   Nostocales cyanobacterium HT-58-2 ARV61428.1    
 Oscil6304_0341   Oscillatoria acuminata PCC 6304 AFY80092.1    
 Osc7112_2098   Oscillatoria nigro-viridis PCC 7112 AFZ06567.1    
 SAMN05444162_4848   Paenibacillaceae bacterium GAS479 SDT53873.1    
 IJ21_12280   Paenibacillus sp. 32O-W ALS26632.1    
 SY83_05190   Paenibacillus swuensis DY6 ANE45793.1    
 SY83_13550   Paenibacillus swuensis DY6 ANE47116.1    
 BDI_3128   Parabacteroides distasonis ATCC 8503 ABR44834.1    
 BFS30_02825   Pedobacter steynii DX4 AOM76191.1    
 PEIBARAKI_0037   Petrimonas sp. IBARAKI BBA13910.1    
 PEIBARAKI_0037   Petrimonas sp. IBARAKI BBA13910.1    
 L21SP3_02126   Phycisphaerae bacterium L21-RPul-D3 AQQ10297.1    
 SMSP2_01474 (fragment)   Phycisphaerae bacterium SM-Chi-D1 AQQ71109.1    
 SMSP2_01473 (fragment)   Phycisphaerae bacterium SM-Chi-D1 AQQ71108.1    
 STSP2_02935   Phycisphaerae bacterium ST-NAGAB-D1 AQT69739.1    
 STSP2_02935   Phycisphaerae bacterium ST-NAGAB-D1 AQT69739.1    
 STSP1_00623   Phycisphaerae bacterium ST-PulAB-D4 ARN56247.1    
 VT85_07875   Planctomyces sp. SH-PL62 AMV37336.1    
 Ple7327_0005   Pleurocapsa sp. PCC 7327 AFY75497.1    
 SAMN05216503_0018   Polaribacter sp. KT25b SDR65405.1    
 P9303_19251   Prochlorococcus marinus str. MIT 9303 ABM78667.1 A2CB07  
 PMT0373   Prochlorococcus marinus str. MIT 9313 CAE20548.1
NP_894206.1
Q7V8H4  
 PSM36_0013   Proteiniphilum saccharofermentans SCD18849.1    
 PSM36_0013   Proteiniphilum saccharofermentans SCD18849.1    
 PSM36_0013   Proteiniphilum saccharofermentans SCD18849.1    
 PSM36_0013   Proteiniphilum saccharofermentans SCD18849.1    
 NIES932_14340   Raphidiopsis curvata NIES-932 BAZ89949.1    
 Riv7116_0388   Rivularia sp. PCC 7116 AFY52992.1    
 Runsl_3226   Runella slithyformis DSM 19594 AEI49603.1    
 SAMD00079811_23730   Scytonema sp. HK-05 NIES-2130 BAY44771.1    
 NIES4073_72720   Scytonema sp. NIES-4073 BAZ26366.1    
 sce4410   Sorangium cellulosum So ce56 CAN94573.1 A9F3D8  
 NIES73_32610   Sphaerospermopsis kisseleviana NIES-73 BAZ81991.1    
 CA265_11430   Sphingobacteriaceae bacterium GW460-11-11-14-LB5 ARS40229.1    
 Sph21_0609   Sphingobacterium sp. 21 ADZ77188.1    
 BV902_20485   Sphingobacterium sp. B29 APU99892.1    
 Slin_6449   Spirosoma linguale DSM 74 ADB42406.1 D2QUC4  
 Sta7437_4348   Stanieria cyanosphaera PCC 7437 AFZ37817.1    
 STA3757_39000   Stanieria sp. NIES-3757 BAU66495.1    
 AA958_30985   Streptomyces sp. CNQ-509 AKH85906.1    
 AA958_10995   Streptomyces sp. CNQ-509 AKH82667.1    
 syc0686_c   Synechococcus elongatus PCC 6301 BAD78876.1 Q5N493  
 Synpcc7942_0854   Synechococcus elongatus PCC 7942 ABB56884.1 Q31PY5  
 sync_0818   Synechococcus sp. CC9311 ABI45792.1 Q0IBZ0  
 Syncc9605_0920   Synechococcus sp. CC9605 ABB34682.1 Q3AL50  
 Syncc9902_1489   Synechococcus sp. CC9902 ABB26447.1 Q3AVE4  
 KR100_11500   Synechococcus sp. KORDI-100 AII43980.1    
 KR52_12350   Synechococcus sp. KORDI-52 AII49921.1    
 NIES970_25530   Synechococcus sp. NIES-970 BAW97599.1    
 Syn6312_1443   Synechococcus sp. PCC 6312 AFY60612.1    
 SYNPCC7002_A2862   Synechococcus sp. PCC 7002 ACB00830.1 B1XNC0  
 AWQ21_14395   Synechococcus sp. PCC 7003 ANV85435.1    
 AWQ22_14635   Synechococcus sp. PCC 7117 ANV88590.1    
 S7335_4075   Synechococcus sp. PCC 7335 EDX86371.1 B4WMW2  
 AWQ24_14570   Synechococcus sp. PCC 8807 ANV91745.1    
 SynRCC307_1749 (fragment)   Synechococcus sp. RCC307 CAK28652.1 A5GUU3  
 SynRCC307_1748 (fragment)   Synechococcus sp. RCC307 CAK28651.1 A5GUU2  
 RS9916_32457   Synechococcus sp. RS9916 EAU74317.1 Q05XA3  
 BM449_11850   Synechococcus sp. SynAce01 APD48808.1    
 M744_12475   Synechococcus sp. UTEX 2973 AJD58588.1    
 SynWH7803_1695   Synechococcus sp. WH 7803 CAK24121.1 A5GMF6  
 WB44_01490   Synechococcus sp. WH 8020 AKN60016.1    
 SYNW1593   Synechococcus sp. WH 8102 CAE08108.1
NP_897686.1
Q7U5V0  
 SynWH8103_01804   Synechococcus sp. WH 8103 CRY92529.1    
 Syncc8109_1822   Synechococcus sp. WH 8109 AHF64174.1    
 D082_22130   Synechocystis sp. PCC 6714 AIE74741.1    
 sll1775   Synechocystis sp. PCC 6803 BAA17664.1
AGF51352.1
ALJ67362.1
BAK49836.1
NP_440984.1
P73619  
 SYNGTI_1088 (Sll1775)   Synechocystis sp. PCC 6803 substr. GT-I BAL28835.1    
 SYNPCCN_1087 (Sll1775)   Synechocystis sp. PCC 6803 substr. PCC-N BAL32004.1    
 SYNPCCP_1087 (Sll1775)   Synechocystis sp. PCC 6803 substr. PCC-P BAL35173.1    
 AciPR4_0477   Terriglobus saanensis SP1PR4 ADV81312.1 E1N0R3  
 AciPR4_4219   Terriglobus saanensis SP1PR4 ADV84964.1 E1N2D0  
 BW730_09520   Tessaracoccus sp. NSG39 AQP47693.1    
 β-glucosidase (TxGH116;Thexy_2211) 3.2.1.21
3.2.1.45
Thermoanaerobacterium xylanolyticum LX-11 AEF18218.1   5BVU[A]
5BX2[A]
5BX3[A]
5BX4[A]
5BX5[A]
5FJS[A,B]
5NCX[A]
5NPF[A]
5O0S[A]
 Tter_0211   Thermobaculum terrenum ATCC BAA-798 ACZ41133.1 D1CDX7  
 Tter_2468   Thermobaculum terrenum ATCC BAA-798 ACZ43361.1 D1CHZ0  
 THTE_0963   Thermogutta terrifontis R1 ASV73565.1    
 THTE_0963   Thermogutta terrifontis R1 ASV73565.1    
 THTE_2430   Thermogutta terrifontis R1 ASV75032.1    
 tlr0193   Thermosynechococcus elongatus BP-1 BAC07746.1
NP_680984.1
Q8DMC7  
 NK55_01065   Thermosynechococcus sp. NK55a AHB87592.1    
 NIES2134_12360   Thermosynechococcus vulcanus NIES-2134 BAY51927.1    
 NIES37_63430   Tolypothrix tenuis PCC 7101 NIES-37 BAZ02331.1    
 TREAZ_3166 (fragment)   Treponema azotonutricium ZAS-9 AEF82991.1    
 Tery_3568   Trichodesmium erythraeum IMS101 ABG52652.1 Q10YM2  
 Ava_1096   Trichormus variabilis ATCC 29413 ABA20720.1 Q3ME66  
 NIES23_12260   Trichormus variabilis NIES-23 BAY68440.1    
 K08M4_42380   Vibrio alginolyticus K08M4 ARP40890.1    
 A134_21270   Vibrio crassostreae 9CS106 ANP78873.1    
 AL536_04035   Vibrio fluvialis ATCC 33809 AMF92653.1    
 BSQ33_16595   Vibrio gazogenes ATCC 43942 ASA57394.1    
 VS_II1384   Vibrio tasmaniensis LGP32 CAV27494.1 B7VTD0  
 AXE80_02935   Wenyingzhuangia fucanilytica CZ1127 ANW95304.1    
 AXE80_03285   Wenyingzhuangia fucanilytica CZ1127 ANW95366.1    
 AXE80_02925   Wenyingzhuangia fucanilytica CZ1127 ANW95302.1    
 AXE80_03295   Wenyingzhuangia fucanilytica CZ1127 ANW97415.1    
 AXE80_03420   Wenyingzhuangia fucanilytica CZ1127 ANW95383.1    
 BA177_04520   Woeseia oceani XK5 ANO50576.1    
 zobellia_454   Zobellia galactanivorans DsiJT CAZ94527.1    
 zobellia_456   Zobellia galactanivorans DsiJT CAZ94529.1    
Eukaryota
Protein Name EC#OrganismGenBank UniprotPDB/3D
 AaeL_AAEL001478   Aedes aegypti LIVERPOOL EAT47379.1 Q17L47  
 At3g24180   Arabidopsis thaliana BAE99039.1
AAL38843.1
AEE76868.1
AEE76869.1
BAB01359.1
NP_001030757.1
NP_189060.2
Q8VZ08  
 At5g49900   Arabidopsis thaliana AAQ65174.1
AAO00842.1
AED95869.1
ANM69564.1
ANM69565.1
BAA97011.1
BAE99037.1
BAH19567.1
NP_199801.2
Q8GUI9  
 At4g10060/T5L19.190   Arabidopsis thaliana NP_192744.3
AAN46866.1
AEE82834.1
ANM67377.1
CAB39630.1
CAB78129.1
F4JLJ2  
 At1g33700   Arabidopsis thaliana NP_174631.2
AAF97289.1
AAO42222.1
AEE31614.1
AEE31615.1
ANM58169.1
ANM58170.1
NP_001031135.1
F4HR96  
 ORF   Ascaris suum ADY40283.1    
 ORF (fragment)   Ascaris suum ADY41606.1    
 ORF (fragment)   Ascaris suum ADY41918.1    
 CBG08749   Caenorhabditis briggsae CAE64133.1 A8X7A9  
 CBG10433   Caenorhabditis briggsae CAE65467.1    
 Y105E8A.10a / Y105E8A.10b / Y105E8A.10c   Caenorhabditis elegans Bristol N2 CAD21661.1
CAC48128.1
CAH04764.1
NP_001021680.1
NP_001021681.1
NP_001021682.1
Q8WQB2  
 R08F11.1 (frameshift)   Caenorhabditis elegans Bristol N2 AAB54243.1
CCD72306.1
CCD72306.2
NP_504047.1
O01893  
 ORF   Callorhinchus milii AFO96150.1    
 ORF (fragment)   Capsella grandiflora ADG37970.1 D6PNN8  
 ORF (fragment)   Capsella grandiflora ADG37971.1 D6PNN9  
 ORF (fragment)   Capsella grandiflora ADG37974.1 D6PNP2  
 ORF (fragment)   Capsella grandiflora ADG38504.1 D6PQ72  
 ORF (fragment)   Capsella grandiflora AEN83322.1    
 ORF (fragment)   Capsella rubella AEN81036.1    
 ORF (fragment)   Capsella rubella AEN81041.1    
 ORF (fragment)   Capsella rubella AEN82035.1    
 ORF (fragment)   Capsella rubella AEN83325.1    
 LOC100187229   Ciona intestinalis XP_002127036.1    
 bile acid β-glucosidase (fragment)   Ctenopharyngodon idella ACF57667.1 B5AFK6  
 ORF (fragment)   Dendrobium nobile ADC68237.1 D3Y115  
 DDB_G0292446   Dictyostelium discoideum AX4 EAL61202.1    
 Dbus_chr2Lg2029   Drosophila busckii ALC39944.1    
 Dmel_CG33090 (CG33090)   Drosophila melanogaster AAO41192.2
AAL13692.1
ABC86280.1
ACH92150.1
ADC53514.1
AHN54440.1
AHN54441.1
AHN54442.1
NP_788055.2
B5RIG1
Q7KT91
 
 acid β-glucosidase 2 / β-glucosylceramidase 2 (Gba2) (ER;non-lysosomal;bile) 3.2.1.45 Homo sapiens NP_065995.1
AAG44660.1
AAH11363.1
BAB13431.1
BAB55430.1
BAG59862.1
BAH12232.1
CAC83792.1
CAD38976.1
CAI10981.1
CAI10982.1
CAI10983.1
EAW58346.1
EAW58347.1
EAW58348.1
EAW58349.1
D3DRP2
Q5TCV6
Q9HCG7
 
 predicted protein (fragment)   Hordeum vulgare subsp. vulgare BAJ97391.1    
 ORF (Gba2)   Ictalurus punctatus AHH37418.1    
 ORF (fragment)   Lolium perenne AFA26156.1    
 non-lysosomal glucosylceramidase (Gba2)   Macaca mulatta AFE66625.1
AFI35128.1
   
 MICPUN_55788   Micromonas commoda sp. RCC299 ACO61507.1 C1DYY0  
 MICPUCDRAFT_48400   Micromonas pusilla CCMP1545 EEH53657.1 C1N2V6  
 acid β-glucosidase 2 / glucosylceramidase 2 (Gba2;Kiaa1605) (non-lysosomal;cytosolic;bile) 3.2.1.45 Mus musculus CAM17042.1
AAH56935.1
BAC40785.1
BAD32491.1
CAM17043.1
NP_766280.1
Q69ZF3
Q6PGM3
 
 mCG_19285 (Gba2) (fragment)   Mus musculus mixed EDL02463.1    
 mCG_19285 (Gba2)   Mus musculus mixed EDL02461.1    
 mCG_19285 (Gba2) (fragment)   Mus musculus mixed EDL02462.1    
 ORF (fragment)   Musca domestica ALHF AFP63561.1    
 glucosidase, beta 2, partial (fragment)   Mustela putorius furo AER98955.1    
 β-glucosidase 2, partial (fragment)   Mustela putorius furo AER98954.1    
 β-glucosidase 2, partial (fragment)   Mustela putorius furo AER98956.1    
 ORF (fragment)   Neslia paniculata ADG37976.1 D6PNP4  
 ORF (fragment)   Neslia paniculata ADG38508.1 D6PQ76  
 OsI_25831   Oryza sativa Indica Group EEC81952.1 B8B5P4  
 OsI_34005   Oryza sativa Indica Group EEC67156.1 B8BHF7  
 OsI_024930 (fragments)   Oryza sativa Indica Group EAZ03698.1    
 OsI_032861   Oryza sativa Indica Group EAY78902.1    
 OsI_034437   Oryza sativa Indica Group EAY80478.1    
 OsI_026592 (fragment)   Oryza sativa Indica Group EAZ05360.1    
 OsJ_24071   Oryza sativa Japonica Group EEE67087.1
BAT01281.1
B9FX00  
 OsJ_31868   Oryza sativa Japonica Group EEE51125.1 B9G678  
 Os08g0111200   Oryza sativa Japonica Group BAF22739.1
BAD09496.1
BAD09542.1
BAG92914.1
BAT03507.1
BAT03508.1
EAZ41282.1
NP_001060825.1
Q6ZC53  
 Os07g0444000 (fragment)   Oryza sativa Japonica Group BAF21443.1
NP_001059529.1
Q0D6T0  
 Os10g0473400   Oryza sativa Japonica Group BAF26747.1
AAG16864.1
AAL31035.1
AAP54244.2
BAG90602.1
BAT11271.1
BAT11272.1
EAZ16400.1
NP_001064833.1
Q7XDG7  
 Os11g0242100   Oryza sativa Japonica Group BAF27951.1
AAX95400.1
ABA92328.1
BAG93831.1
BAT13385.1
EAZ17950.1
NP_001067588.1
Q2R859  
 OsJ_023125 (fragments)   Oryza sativa Japonica Group EAZ39642.1 A3BJA3  
 Gba2   Pan troglodytes XP_001167923.1
BAK63646.1
XP_520565.1
   
 ORF (fragment)   Phaseolus vulgaris AGV54567.1    
 PHYPADRAFT_122471   Physcomitrella patens subsp. patens EDQ75122.1 A9S119  
 PHYPADRAFT_189506   Physcomitrella patens subsp. patens EDQ64036.1 A9SXS9  
 glucosylceramidase 2 (Gba2)   Rattus norvegicus AAH88200.1
EDL98757.1
Q5M868  
 Smp_155750.1   Schistosoma mansoni Puerto Rico CAZ33749.1
CAZ33750.1
CCD79501.1
CCD79502.1
C4QE81  
 SRAE_1000207300   Strongyloides ratti ED321 Heterogonic CEF63815.1    
 GSTEN:00035263:G:001 (fragment)   Tetraodon nigroviridis CAG12815.1 Q4RFL7  
 VIGAN_08128200 (Vigan.08g128200)   Vigna angularis var. angularis BAT94661.1    
 VIGAN_01552300 (Vigan.01g552300)   Vigna angularis var. angularis BAT77410.1    
 GSVIVT00035303001   Vitis vinifera CAO46877.1 A7QC94  
 GSVIVT00021808001   Vitis vinifera CAO16273.1 A7PPW2  
 GSVIVT00020494001   Vitis vinifera CAO71587.1 A7NXU8  
 VITISV_019326 (possible fragment)   Vitis vinifera CAN61187.1 A5BBB7  
 Loc100249401   Vitis vinifera XP_002285674.1    
 VITISV_016690 (possible fragment)   Vitis vinifera CAN61857.1 A5BW60  
 Unknown (protein for IMAGE:7678184) (fragment)   Xenopus tropicalis AAI60640.1 B1H1K5  
 unknown (fragment)   Zea mays ACG47878.1    
 unknown (probable fragment)   Zea mays B73 ACL53681.1
ACN33233.1
B8A0I2  
unclassified
Protein Name EC#OrganismGenBank UniprotPDB/3D
 BN138_999   termite gut metagenome CCO21811.1    
 HGMM_F51E10C08   uncultured prokaryote BAL57596.1    
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