Activities in Family	peptidoglycan lytic transglycosylase (EC 3.2.1.-)
Mechanism	Retaining
Catalytic Nucleophile/Base	carbonyl oxygen of C-2 acetamido group of substrate (inferred)
Catalytic Proton Donor	Glu (experimental)
Note	Corresponds to family 3 of the peptidoglycan lytic transglycosylases described by N.T. Blackburn and A.J. Clarke (2001) J. Mol. Evol. 52, 78-84
External resources	CAZypedia;
Statistics	GenBank accession (9494); Uniprot accession (767); PDB accession (13); 3D entries (3); cryst (0)

Bacteria
Protein Name	EC#	Organism	GenBank	Uniprot	PDB/3D Carbohydrate Ligands Resolution (Å)
lytic murein transglycosylase B (MltB;b2701;Slt35)	4.2.2.n1	Escherichia coli str. K-12 substr. MG1655	AAB60060.1 AAC75743.1 AIZ90258.1 ALI39582.1 AMC95626.1 AVI52882.1 AYG18309.1 NP_417181.1	P41052	1D0K[A] β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-α-D-GlcpNAc β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-β-D-GlcpNAc 2.02 1D0L[A] β-D-GlcpNAc4SO3-(1-1)-<non_carb> 1.97 1D0M[A] β-D-GlcpNAc-(1-4)-α-D-GlcpNAc β-D-GlcpNAc4SO3-(1-1)-<non_carb> 2.47 1LTM[A] 1.70 1QDR[A] 2.10 1QDT[A] 2.10 1QUS[A] 1.70 1QUT[A] β-D-GlcpNAc 2.44
soluble lytic transglycosylase (SltB1;PA4001)		Pseudomonas aeruginosa PAO1	AAG07388.1		4ANR[A] 1.84 5O8X[A,B] 2.50
exo-lytic transglycosylase (SltB3;PA3992)	4.2.2.n1	Pseudomonas aeruginosa PAO1	AAG07379.1		5ANZ[A] 1.61 5AO7[A] β-D-GlcpNAc 2.09 5AO8[A] β-D-GlcpNAc β-D-GlcpNAc-(1-4)[<non_carb>-(1-3)]-β-D-GlcpNAc-(1-1)-methyl 2.09
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